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Displaying drugs 11476 - 11500 of 12930 in total
Phenethyl Isothiocyanate
Phenethyl Isothiocyanate has been used in trials studying the prevention and treatment of Leukemia, Lung Cancer, Tobacco Use Disorder, and Lymphoproliferative Disorders.
Investigational
Matched Iupac: … (2-isothiocyanatoethyl)benzene …
PPI-1019
Apan (PPI-1019) is developed by Praecis Pharmaceuticals to treat Alzheimer's Disease.
Investigational
Matched Iupac: … -2-phenylethyl]carbamoyl}-2-methylpropyl]-4-methyl-2-(methylamino)pentanamide ... (2R)-N-[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-carbamoyl-3-methylbutyl]carbamoyl}-2-phenylethyl]carbamoyl} …
Glesatinib
Investigational
Matched Iupac: … 3-(3-fluoro-4-{[2-(5-{[(2-methoxyethyl)amino]methyl}pyridin-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl ... )-1-[2-(4-fluorophenyl)acetyl]thiourea …
Olinciguat
Olinciguat is under investigation in clinical trial NCT03892499 (A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator, Olinciguat (IW-1701), in Healthy Volunteers).
Investigational
Matched Iupac: … (2R)-3-[(5-fluoro-2-{1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)-1H-pyrazol-3-yl}pyrimidin-4-yl)amino ... ]-2-hydroxy-2-(trifluoromethyl)propanamide …
Methylmalonic Acid
A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA. [PubChem]
Experimental
Matched Iupac: … 2-methylpropanedioic acid …
Freselestat
Experimental
Investigational
Matched Iupac: … -1-hydroxy-3-methylbutan-2-yl]acetamide ... 2-(5-amino-6-oxo-2-phenyl-1,6-dihydropyrimidin-1-yl)-N-[(1R,2R)-1-(5-tert-butyl-1,3,4-oxadiazol-2-yl) …
Biricodar
The pipecolinate derivative biricodar (VX-710) is a clinically applicable modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1).
Investigational
Matched Iupac: … 1,7-bis(pyridin-3-yl)heptan-4-yl (2S)-1-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxylate …
Cardarine
Cardarine (GW-501516) is a peroxisome proliferator-activator receptor-delta agonist for the potential treatment of dyslipidemia. Cardarine has been investigated for the treatment of Obesity, Lipid Disorders, and Cardiovascular Disease.
Investigational
Matched Iupac: … 2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}acetic …
Avasimibe
Investigational
Matched Iupac: … 1-({[2,6-bis(propan-2-yl)phenoxy]sulfonyl}amino)-2-[2,4,6-tris(propan-2-yl)phenyl]ethan-1-one …
Matched Salts cas: … 166518-61-2 …
Matched Salts cas: … 166518-61-2 …
Piroxicam cinnamate
Experimental
Matched Iupac: … 2-methyl-1,1-dioxo-3-[(pyridin-2-yl)carbamoyl]-2H-1lambda6,2-benzothiazin-4-yl (2E)-3-phenylprop-2-enoate …
Hydroxyethylpromethazine
Experimental
Matched Iupac: … (2-hydroxyethyl)dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]azanium …
Moxalactam (hydrolyzed)
Experimental
Matched Iupac: … (2R)-2-{carboxy[(2S)-2-carboxy-2-(4-hydroxyphenyl)acetamido]methoxymethyl}-5-methylidene-5,6-dihydro- ... 2H-1,3-oxazine-4-carboxylic acid …
Rociletinib
Rociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer.
Investigational
Matched Iupac: … N-{3-[(2-{[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino}-5-(trifluoromethyl)pyrimidin-4-yl)amino] ... phenyl}prop-2-enamide …
Epelsiban
Epelsiban has been investigated for the treatment of Premature Ejaculation.
Investigational
Matched Iupac: … -4-yl)-2-oxoethyl]piperazine-2,5-dione ... (3R,6R)-6-[(2S)-butan-2-yl]-3-(2,3-dihydro-1H-inden-2-yl)-1-[(1R)-1-(2,6-dimethylpyridin-3-yl)-2-(morpholin …
Diethylthiambutene
Experimental
Illicit
Matched Iupac: … [4,4-bis(thiophen-2-yl)but-3-en-2-yl]diethylamine …
Benfluorex
Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. It was patented and manufactured by a French pharmaceutical company Servier. The European Medicines Agency (EMA) recommended withdrawing all benfluorex containing medicines on 18 December 2009. This recommendation was based on the risks (especially fenfluramine-like cardiovascular side-effects)...
Investigational
Withdrawn
Matched Iupac: … 2-({1-[3-(trifluoromethyl)phenyl]propan-2-yl}amino)ethyl benzoate …
Matched Salts cas: … 23642-66-2 …
Matched Salts cas: … 23642-66-2 …
Perfluoro tert-butylcyclohexane
Oxycyte has been used in trials studying the treatment of Traumatic Brain Injury.
Investigational
Matched Iupac: … 1,1,2,2,3,3,4,4,5,5,6-undecafluoro-6-[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]cyclohexane …
Alagebrium
Alagebrium has been investigated for the treatment and prevention of Aging, Heart Failure, Physical Activity, Diabetic Nephropathy, and Cardiovascular Disease, among others.
Investigational
Matched Iupac: … 4,5-dimethyl-3-(2-oxo-2-phenylethyl)-1,3-thiazol-3-ium …
Aspartyl-alanyl-diketopiperazine
Aspartyl-alanyl-diketopiperazine is under investigation in clinical trial NCT03349645 (An Open Label Extension Study to Assess the Safety of Long-Term Treatment With Ampion for Severe OA of the Knee).
Investigational
Matched Iupac: … 2-[(2S,5S)-5-methyl-3,6-dioxopiperazin-2-yl]acetic acid …
Lavendustin A
Experimental
Matched Iupac: … 5-{[(2,5-dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino}-2-hydroxybenzoic acid …
Furethidine
Experimental
Illicit
Matched Iupac: … ethyl 1-{2-[(oxolan-2-yl)methoxy]ethyl}-4-phenylpiperidine-4-carboxylate …
Displaying drugs 11476 - 11500 of 12930 in total