Displaying drugs 1151 - 1175 of 2011 in total
Sevasemten
Sevasemten is under investigation in clinical trial NCT05291091 (Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)).
Investigational
Matched Synonyms: … 2-[(5-fluoropyridin-3-yl)methyl]-6-[2-(2,2,2- trifluoroethoxy)pyrimidin-5-yl]pyridazin-3(2H)-one …
AZD2066
Investigational
Matched Synonyms: … Pyridine, 4-(5-((1r)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4h-1,2,4-triazol-3-yl)- …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
FDL169
Investigational
Matched Synonyms: … 2-(7-ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2(1H)-yl)-N-methyl-N-(2-methylbenzo(D)oxazol-6-yl)acetamide ... 2-(7-ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2(1H)-yl)-N-methyl-N-(2-methylbenzo[D]oxazol-6-yl)acetamide …
Matched Iupac: … 2-[7-ethoxy-4-(3-fluorophenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-methyl-N-(2-methyl-1,3-benzoxazol- …
Matched Iupac: … 2-[7-ethoxy-4-(3-fluorophenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-methyl-N-(2-methyl-1,3-benzoxazol- …
BTZ-043
Investigational
Matched Synonyms: … 2-((2s)-2-methyl-1,4-dioxa-8-azaspiro(4.5)decan-8-yl)-8-nitro-6-trifluoromethyl-4h-1,3-benzothiazin-4 ... 4h-1,3-benzothiazin-4-one, 2-((2s)-2-methyl-1,4-dioxa-8-azaspiro(4.5)dec-8-yl)-8-nitro-6-(trifluoromethyl …
Matched Iupac: … 2-[(2S)-2-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin …
Matched Iupac: … 2-[(2S)-2-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin …
Promethazine
Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171]
Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Synonyms: … (2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine ... N-(2'-dimethylamino-2'-methyl)ethylphenothiazine …
Matched Description: … allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and …
Matched Mixtures name: … Meperidine Hcl and Promethazine Hcl ... Promethazine Hydrochloride and Codeine Phosphate ... Promethazine HCl and Codeine Phosphate …
Matched Categories: … prednisolone and promethazine ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Description: … allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and …
Matched Mixtures name: … Meperidine Hcl and Promethazine Hcl ... Promethazine Hydrochloride and Codeine Phosphate ... Promethazine HCl and Codeine Phosphate …
Matched Categories: … prednisolone and promethazine ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Fluoxymesterone
An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Approved
Illicit
Matched Synonyms: … 17α-Methyl-9α-fluoro-11β-hydroxytesterone ... 11β,17β-Dihydroxy-9α-fluoro-17α-methyl-4-androster-3-one …
Matched Description: … anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Losartan
Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Synonyms: … (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol ... 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole …
Matched Iupac: … (2-butyl-4-chloro-1-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol …
Matched Description: … available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and ... [L7423,L7426] Patients taking losartan should have their renal function and potassium levels monitored …
Matched Mixtures name: … Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide …
Matched Categories: … losartan and diuretics ... losartan and amlodipine ... Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Matched Iupac: … (2-butyl-4-chloro-1-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol …
Matched Description: … available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and ... [L7423,L7426] Patients taking losartan should have their renal function and potassium levels monitored …
Matched Mixtures name: … Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide …
Matched Categories: … losartan and diuretics ... losartan and amlodipine ... Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}-METHYL)-BENZOIC ACID
Experimental
Matched Name: … METHYL)-BENZOIC ACID ... 3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}- …
Matched Iupac: … -methylbutyl]sulfamoyl}methyl)benzoic acid ... 3-({[(1R,2R)-1-{[(1S)-3-carbamimidoyl-1-{[(4-carbamimidoylphenyl)methyl]carbamoyl}propyl]carbamoyl}-2 …
Matched Iupac: … -methylbutyl]sulfamoyl}methyl)benzoic acid ... 3-({[(1R,2R)-1-{[(1S)-3-carbamimidoyl-1-{[(4-carbamimidoylphenyl)methyl]carbamoyl}propyl]carbamoyl}-2 …
17alpha-methyl-3beta,17beta-dihydroxyandrost-4-ene
Experimental
Illicit
Matched Name: … 17alpha-methyl-3beta,17beta-dihydroxyandrost-4-ene …
17Alpha-methyl-3beta,17beta-dihydroxy-5alpha-androstane
Experimental
Illicit
Matched Name: … 17Alpha-methyl-3beta,17beta-dihydroxy-5alpha-androstane …
2-amino-8-methyl-4(1H)-quinazolinone
Experimental
Matched Name: … 2-amino-8-methyl-4(1H)-quinazolinone …
Matched Iupac: … 2-amino-8-methyl-1,4-dihydroquinazolin-4-one …
Matched Iupac: … 2-amino-8-methyl-1,4-dihydroquinazolin-4-one …
4-(Aminosulfonyl)-N-[(3,4,5-Trifluorophenyl)Methyl]-Benzamide
Experimental
Matched Name: … 4-(Aminosulfonyl)-N-[(3,4,5-Trifluorophenyl)Methyl]-Benzamide …
Matched Iupac: … 4-sulfamoyl-N-[(3,4,5-trifluorophenyl)methyl]benzamide …
Matched Iupac: … 4-sulfamoyl-N-[(3,4,5-trifluorophenyl)methyl]benzamide …
4-(Aminosulfonyl)-N-[(2,3,4-Trifluorophenyl)Methyl]-Benzamide
Experimental
Matched Name: … 4-(Aminosulfonyl)-N-[(2,3,4-Trifluorophenyl)Methyl]-Benzamide …
Matched Iupac: … 4-sulfamoyl-N-[(2,3,4-trifluorophenyl)methyl]benzamide …
Matched Iupac: … 4-sulfamoyl-N-[(2,3,4-trifluorophenyl)methyl]benzamide …
DERIVATIVE OF AKLANONIC ACID METHYL ESTER (AAME)
Experimental
Matched Name: … DERIVATIVE OF AKLANONIC ACID METHYL ESTER (AAME) …
Matched Iupac: … methyl 2-{3-[(1R,3S)-1,3-dihydroxypentyl]-4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl}acetate …
Matched Iupac: … methyl 2-{3-[(1R,3S)-1,3-dihydroxypentyl]-4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl}acetate …
(3R)-8-(dioxidosulfanyl)-3-methyl-1,2,3,4-tetrahydroquinoline
Experimental
Matched Name: … (3R)-8-(dioxidosulfanyl)-3-methyl-1,2,3,4-tetrahydroquinoline …
Matched Iupac: … (3R)-3-methyl-8-sulfonyl-1,2,3,4-tetrahydroquinoline …
Matched Iupac: … (3R)-3-methyl-8-sulfonyl-1,2,3,4-tetrahydroquinoline …
4-PHOSPHONOOXY-PHENYL-METHYL-[4-PHOSPHONOOXY]BENZEN
Experimental
Matched Name: … 4-PHOSPHONOOXY-PHENYL-METHYL-[4-PHOSPHONOOXY]BENZEN …
Matched Iupac: … (4-{[4-(phosphonooxy)phenyl]methyl}phenoxy)phosphonic acid …
Matched Iupac: … (4-{[4-(phosphonooxy)phenyl]methyl}phenoxy)phosphonic acid …
2-PHENYLAMINO-4-METHYL-5-ACETYL THIAZOLE
Experimental
Matched Name: … 2-PHENYLAMINO-4-METHYL-5-ACETYL THIAZOLE …
Matched Iupac: … 1-[4-methyl-2-(phenylamino)-1,3-thiazol-5-yl]ethan-1-one …
Matched Iupac: … 1-[4-methyl-2-(phenylamino)-1,3-thiazol-5-yl]ethan-1-one …
9-(N-methyl-L-isoleucine)-cyclosporin A
9-(N-methyl-L-isoleucine)-cyclosporin A (NIM811) has been used in trials studying the treatment of Chronic Hepatitis C Genotype-1 Relapse.
Investigational
Matched Name: … 9-(N-methyl-L-isoleucine)-cyclosporin A …
Matched Description: … 9-(N-methyl-L-isoleucine)-cyclosporin A (NIM811) has been used in trials studying the treatment of Chronic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … 9-(N-methyl-L-isoleucine)-cyclosporin A (NIM811) has been used in trials studying the treatment of Chronic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Delpazolid
Delpazolid (LCB01-0371) is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).
Investigational
Matched Synonyms: … (5R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one ... (5R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin ... 2-oxazolidinone, 3-(4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl)-5-(hydroxymethyl) …
Matched Iupac: … (5R)-3-[3-fluoro-4-(1-methyl-1,4,5,6-tetrahydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin …
Matched Categories: … Protein Synthesis Inhibitors …
Matched Iupac: … (5R)-3-[3-fluoro-4-(1-methyl-1,4,5,6-tetrahydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin …
Matched Categories: … Protein Synthesis Inhibitors …
Morphine
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Synonyms: … (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol ... (5α,6α)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol ... (5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol …
Matched Iupac: … (1S,5R,13R,14S,17R)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15 …
Matched Description: … [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk ... strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and ... [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids …
Matched Categories: … morphine and antispasmodics …
Matched Iupac: … (1S,5R,13R,14S,17R)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15 …
Matched Description: … [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk ... strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and ... [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids …
Matched Categories: … morphine and antispasmodics …
Cefuroxime
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Synonyms: … (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo …
Matched Iupac: … (6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo …
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Matched Iupac: … (6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo …
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
DSM-265
DSM265 has been used in trials studying the prevention and treatment of Malaria.
Investigational
Matched Synonyms: … 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin ... 2-(1,1-Difluoroethyl)-5-methyl-N-[4-(pentafluoro-λ6-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7 ... Sulfur, (4-((2-(1,1-difluoroethyl)-5-methyl(1,2,4)triazolo(1,5-a)pyrimidin-7-yl)amino)phenyl)pentafluoro …
Matched Iupac: … 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin …
Matched Description: … DSM265 has been used in trials studying the prevention and treatment of Malaria. …
Matched Iupac: … 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin …
Matched Description: … DSM265 has been used in trials studying the prevention and treatment of Malaria. …
Berotralstat
Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary angioedema (HAE). It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE. Berotralstat is strictly used to...
Approved
Matched Synonyms: … (+)-1-(3-(aminomethyl) phenyl)-N-(5-((3-cyanophenyl)(cyclopropylmethylamino)methyl)-2-fluorophenyl)-3 ... (R)-1-(3-(aminomethyl) phenyl)-N-(5-((3- cyanophenyl)(cyclopropylmethylamino)methyl)-2-fluorophenyl)- ... 2-[3-(aminomethyl)phenyl]-N-[5-[(R)-(3-cyanophenyl)-(cyclopropylmethylamino)methyl]-2-fluorophenyl]-5 …
Matched Iupac: … 1-[3-(aminomethyl)phenyl]-N-{5-[(R)-(3-cyanophenyl)[(cyclopropylmethyl)amino]methyl]-2-fluorophenyl}- …
Matched Description: … pediatric patients 12 years and older. ... activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and ... [L26661] Berotralstat was approved by the European Commission on April 30, 2021 [L41965] and by Health …
Matched Categories: … Blood and Blood Forming Organs …
Matched Iupac: … 1-[3-(aminomethyl)phenyl]-N-{5-[(R)-(3-cyanophenyl)[(cyclopropylmethyl)amino]methyl]-2-fluorophenyl}- …
Matched Description: … pediatric patients 12 years and older. ... activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and ... [L26661] Berotralstat was approved by the European Commission on April 30, 2021 [L41965] and by Health …
Matched Categories: … Blood and Blood Forming Organs …
Febuxostat
Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout...
Approved
Matched Synonyms: … 2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acid …
Matched Iupac: … 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid …
Matched Description: … Febuxostat works by inhibiting the activity of an enzyme that is responsible for the synthesis of uric ... granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and ... further deposition of uric acid crystal deposition in bones, joints, tissues, and other organs in the …
Matched Iupac: … 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid …
Matched Description: … Febuxostat works by inhibiting the activity of an enzyme that is responsible for the synthesis of uric ... granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and ... further deposition of uric acid crystal deposition in bones, joints, tissues, and other organs in the …
Displaying drugs 1151 - 1175 of 2011 in total