Did you mean 1,3 205 2?
Displaying drugs 11851 - 11875 of 13379 in total
Glypromate
Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 which inhibits caspase III dependent apoptosis, for the potential treatment of neurodegenerative diseases by IV infusion. In December 2008, the company discontinued further development of the drug after it failed to show an observable effect.
Investigational
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}pentanedioic acid …
Matched Description: … (glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 …
Matched Description: … (glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 …
Lobaplatin
Lobaplatin has been used in trials studying the treatment of Breast Cancer, Hepatocellular Carcinoma, and Lobaplatin and Gemcitabine in Combination, Second-line Treatments on Advanced Osteosarcoma.
Investigational
Matched Iupac: … platinum(2+) 1-[(1R,2R)-2-(aminomethyl)cyclobutyl]methanamine (2S)-2-oxidopropanoate …
Chlorbenzoxamine
Experimental
Matched Iupac: … 1-{2-[(2-chlorophenyl)(phenyl)methoxy]ethyl}-4-[(2-methylphenyl)methyl]piperazine …
Pargeverine
Experimental
Matched Iupac: … 2-(dimethylamino)ethyl 2,2-diphenyl-2-(prop-2-yn-1-yloxy)acetate …
Matched Salts cas: … 2765-97-1 …
Matched Salts cas: … 2765-97-1 …
Filorexant
Filorexant has been used in trials studying the prevention and treatment of Migraine, Headache, Polysomnography, Diabetic Neuropathy, Painful, and Major Depressive Disorder, Recurrent.
Investigational
Matched Iupac: … 2-{2-[(2R,5R)-5-{[(5-fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidine-1-carbonyl]-4-methylphenyl}pyrimidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Trimazosin
Trimazosin is a sympatholytic alpha blocker.
Experimental
Matched Iupac: … 2-hydroxy-2-methylpropyl 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate …
Matched Categories: … Peripheral alpha-1 blockers ... Heterocyclic Compounds, 1-Ring ... Adrenergic alpha-1 Receptor Antagonists …
Matched Categories: … Peripheral alpha-1 blockers ... Heterocyclic Compounds, 1-Ring ... Adrenergic alpha-1 Receptor Antagonists …
Rigosertib
Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others.
Investigational
Matched Iupac: … 2-[(2-methoxy-5-{[(E)-2-(2,4,6-trimethoxyphenyl)ethenesulfonyl]methyl}phenyl)amino]acetic acid …
Etrumadenant
Investigational
Matched Iupac: … 3-[2-amino-6-(1-{[6-(2-hydroxypropan-2-yl)pyridin-2-yl]methyl}-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl]- ... 2-methylbenzonitrile …
GS-9191
GS-9191 is under investigation in clinical trial NCT00499967 (Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts).
Investigational
Matched Iupac: … )-1-oxo-3-phenylpropan-2-yl]amino})phosphoryl]amino}-3-phenylpropanoate ... 2-methylpropyl (2S)-2-{[({2-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]ethoxy}methyl)({[(2S)-1-(2-methylpropoxy …
Teverelix
A synthetic decapeptide, water-soluble Gonadotropin-releasing hormone antagonist. It has reached phase II clinical trials.
Investigational
Matched Iupac: … -1-oxo-6-[(propan-2-yl)amino]hexan-2-yl]carbamoyl}-3-methylbutyl]-2-[(2S)-2-[(2S)-2-[(2R)-2-[(2R)-3-( ... (2R)-6-(carbamoylamino)-N-[(1S)-1-{[(2S)-1-[(2S)-2-{[(1R)-1-carbamoylethyl]carbamoyl}pyrrolidin-1-yl] ... 4-chlorophenyl)-2-[(2R)-2-acetamido-3-(naphthalen-2-yl)propanamido]propanamido]-3-(pyridin-3-yl)propanamido ... ]-3-hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]hexanamide …
Mibampator
Mibampator has been used in trials studying the treatment of Alzheimer's Disease.
Investigational
Matched Iupac: … N-[(2R)-2-[4'-(2-methanesulfonamidoethyl)-[1,1'-biphenyl]-4-yl]propyl]propane-2-sulfonamide …
Pexiganan
Pexiganan is under investigation in clinical trial NCT01594762 (Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers).
Investigational
Matched Iupac: … )-5-amino-1-carbamoylpentyl]carbamoyl}pentyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-methylbutyl]carbamoyl ... )-2-(2-aminoacetamido)-3-methylpentanamido]acetamido}hexanamido]-3-phenylpropanamido]-4-methylpentanamido ... (2S)-6-amino-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-5-amino-1-{[(1S,2S)-1-{[(1S)-1-{[(1S)-5-amino-1-{[(1S ... ]hexanamido]hexanamido]propanamido]hexanamido]hexanamido]-3-phenylpropanamido]acetamido}hexanamide ... -2-[(2S)-6-amino-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-{2-[(2S,3S …
Seltorexant
Seltorexant is under investigation in clinical trial NCT03494907 (A Study to Evaluate the Effects of Single-dose Seltorexant on Electrocardiogram Intervals in Healthy Adult Participants).
Investigational
Matched Iupac: … 2-[(3aR,6aS)-5-[2-fluoro-6-(2H-1,2,3-triazol-2-yl)benzoyl]-octahydropyrrolo[3,4-c]pyrrol-2-yl]-4,6-dimethylpyrimidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
HSD-016
Hsd 016 is under investigation in clinical trial NCT00838461 (Study Evaluating the Safety, Pharmacokinetics (PK), and Pharmacodynamices (PD) of HSD-016).
Investigational
Matched Iupac: … (2R)-1,1,1-trifluoro-2-(3-{[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl]sulfonyl ... }phenyl)propan-2-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Melagatran
Experimental
Matched Iupac: … 2-{[(1R)-2-[(2S)-2-{[(4-carbamimidoylphenyl)methyl]carbamoyl}azetidin-1-yl]-1-cyclohexyl-2-oxoethyl]amino …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Thiorphan
A potent inhibitor of membrane metalloendopeptidase (enkephalinase). Thiorphan potentiates morphine-induced analgesia and attenuates naloxone-precipitated withdrawal symptoms.
Experimental
Matched Iupac: … 2-[(2S)-2-benzyl-3-sulfanylpropanamido]acetic acid …
Zinc citrate
Zinc citrate is a zinc salt of citric acid. It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral administration .
Investigational
Matched Iupac: … trizinc(2+) ion bis(2-hydroxypropane-1,2,3-tricarboxylate) …
Matched Salts cas: … 178326-57-3 …
Matched Salts cas: … 178326-57-3 …
Clofibride
Experimental
Matched Iupac: … 3-(dimethylcarbamoyl)propyl 2-(4-chlorophenoxy)-2-methylpropanoate …
Acetylcysteine magnesium
Experimental
Matched Iupac: … magnesium(2+) bis((2R)-2-acetamido-3-sulfanylpropanoate) …
Perfosfamide
Perfosfamide has been used in trials studying the treatment of Lymphoma, Neuroblastoma, and Multiple Myeloma and Plasma Cell Neoplasm.
Investigational
Matched Iupac: … (2R,4R)-2-[bis(2-chloroethyl)amino]-4-hydroperoxy-1,3,2lambda5-oxazaphosphinan-2-one …
Iproclozide
Iproclozide is an irreversible and selective hydrazine class based monoamine oxidase inhibitor (MAOI). Although it was employed as an antidepressant for a time, the fact that the agent is capable of causing fulminant hepatitis and that its use has been documented as the cause for at least three reported fatalities...
Withdrawn
Matched Iupac: … 2-(4-chlorophenoxy)-N'-(propan-2-yl)acetohydrazide …
Pro-Pro-Thr-Val-Pro-Thr-Arg
Investigational
Matched Iupac: … (2S)-5-carbamimidamido-2-[(2S,3R)-3-hydroxy-2-{[(2S)-1-[(2S)-2-[(2S,3R)-3-hydroxy-2-{[(2S)-1-[(2S)-pyrrolidine ... -2-carbonyl]pyrrolidin-2-yl]formamido}butanamido]-3-methylbutanoyl]pyrrolidin-2-yl]formamido}butanamido …
Quinacrine mustard
Experimental
Matched Iupac: … N-{5-[bis(2-chloroethyl)amino]pentan-2-yl}-6-chloro-2-methoxyacridin-9-amine …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
N-ACETYL-L-PHENYLALANYL-4-[DIFLUORO(PHOSPHONO)METHYL]-L-PHENYLALANINAMIDE
Experimental
Matched Iupac: … ({4-[(2S)-2-carbamoyl-2-[(2S)-2-acetamido-3-phenylpropanamido]ethyl]phenyl}difluoromethyl)phosphonic …
Fominoben
Fominoben is an antitussive agent.
Experimental
Withdrawn
Matched Iupac: … N-[3-chloro-2-({methyl[2-(morpholin-4-yl)-2-oxoethyl]amino}methyl)phenyl]benzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 11851 - 11875 of 13379 in total