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Displaying drugs 1176 - 1200 of 1382 in total

Leflunomide

Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Approved
Investigational
Matched Description: … Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. ... belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …
Matched Products: … LEFLUNOMID 1A PHARMA 10MG ... LEFLUNOMID 1A PHARMA 20MG …

Timolol

Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the FDA in 1978. This drug is marketed by several manufacturers...
Approved
Matched Description: … of conditions such as open-angle glaucoma and hypertension. ... [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management …
Matched Mixtures name: … KATALJİN BUHARLAŞAN MERHEM, 12,5 G ... Bimatoprost/Timolol 1A Pharma 0,3 mg/ml + 5 mg/ml - Augentropfen, Lösung ... Dorzolamid + Timolol 1A Pharma 20 mg/ml + 5 mg/ml - Augentropfen, Lösung …
Matched Categories: … timolol and thiazides ... Antiglaucoma Preparations and Miotics ... Beta Blocking Agents and Thiazides ... timolol, thiazides and other diuretics ... Beta Blocking Agents, Non-Selective, and Thiazides …
Matched Products: … TIMOLOL 0.1% AT 1A PHARMA ... TIMOLOL 0.5% AT 1A PHARMA ... TIMOLOL 0.25% AT 1A PHARMA …

Ambroxol

Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the...
Approved
Investigational
Matched Description: … in providing protection against infection and irritating agents. ... It stimulates synthesis and release of surfactant by type II pneumocytes. ... The substance is a mucoactive drug with several properties including secretolytic and secretomotoric …
Matched Categories: … Cough and Cold Preparations ... clenbuterol and ambroxol …
Matched Products: … AMBROXOL 30 TAB 1A PHARMA ... AMBROXOL 15 SAFT 1A PHARMA ... AMBROXOL 30 SAFT 1A PHARMA …

Dental Mesenchymal Pulp Stem Cells

Dental pulp is a soft, connective tissue present in the dental crown of both third molar and first premolar teeth. Dental pulp stem cells (DPSCs) exhibit fibro-blast like plasticity and adherent properties. They are harvested through surgical extraction of wisdom teeth from adults; this procedure is favoured as it is...
Investigational
Matched Synonyms: … Allogenic Human Dental Pulp Stem Cells …
Matched Description: … DPSCs can remain stable in media once extracted, and have a high proliferation and regeneration capacity ... DPSCs have multiple properties, and express surface antigens like CD90, CD29, and CD105 but not CD14 ... Dental pulp is a soft, connective tissue present in the dental crown of both third molar and first premolar …

TOL-101

Investigational
Matched Synonyms: … Murine IgM monoclonal antibody specific for the human alpha, beta T cell receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins …

RGX-121

RGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the central nervous system.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus (AAV) vector of serotype 9 expressing human iduronate …
Matched Name: … RGX-121 …
Matched Description: … RGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the …

Tisotumab vedotin

Tisotumab vedotin is a tissue factor-directed antibody-drug conjugate (ADC) comprised of an anti-tissue factor (TF) human IgG1-kappa antibody conjugated to monomethyl auristatin E (MMAE), a microtubule-disrupting agent, via a protease-cleavable valine-citrulline linker. Each monoclonal antibody molecule carries an average of four MMAE molecules. Tisotumab vedotin is the first TF-directed ADC...
Approved
Matched Synonyms: … HuMax-TF-ADC …
Matched Description: … vedotin is a tissue factor-directed antibody-drug conjugate (ADC) comprised of an anti-tissue factor (TF) human ... head and neck cancers. ... tumor-associated angiogenesis, progression, and metastasis for tumor survival. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Metoprolol

Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Description: … widely prescribed in the Netherlands, New Zealand, and the US. ... Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives ... [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is …
Matched Mixtures name: … METOPROLOLSUC 1A PL95/12.5 ... METOPROLOLSUC 1A PL95/12.5 ... METOPROLOLSUC 1A PL95/12.5 …
Matched Categories: … Beta Blocking Agents and Thiazides ... metoprolol and felodipine ... metoprolol and ivabradine ... metoprolol and thiazides ... metoprolol and amlodipine …
Matched Products: … OPEMOL XR 12.5 MG FILM KAPLI TABLET ,20 ADET ... METOPROLOL 50 1A PHARMA ... METOPROLOL 100 1A PHARMA …

Reveglucosidase alfa

Investigational
Matched Synonyms: … Des-(2-7)-human insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal …

Solifenacin

Solifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency. It has a long duration of action as it is usually taken once daily. Solifenacin was granted FDA approval on 19 November 2004.
Approved
Matched Description: … muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and …
Matched Categories: … tamsulosin and solifenacin ... Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … SOLIFENACIN 1A PHARMA 5MG ... SOLIFENACIN 1A PHARMA 10MG ... Solifenacin 1A Pharma 5 mg - Filmtabletten …

Tralesinidase alfa

Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Synonyms: … Recombinant human NAGLU-insulin-like growth factor II ... Recombinant human alpha-N-acetylglucosaminidase-insulin-like growth factor-2 …
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

Spironolactone

Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … [A178192] It promotes sodium and water excretion and potassium retention. ... It binds to mineralocorticoid receptors and functions as aldosterone antagonists. ... [L44602] Off-label uses of spironolactone include hirsutism, female pattern hair loss, and adult acne …
Matched Mixtures name: … Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SPIRONOLACTON 1A PHA 50MG ... SPIRONOLACTON 1A PHA 100MG …

alpha-Linolenic acid

Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (9Z,12Z,15Z)-Octadecatrienoic acid ... 9-cis,12-cis,15-cis-octadecatrienoic acid …
Matched Iupac: … (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid …
Matched Description: … It is a component of many common vegetable oils and is important to human nutrition. …

AMT-130

Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 5 encoding a microRNA targeted to human Huntingtin gene …

CypCaps

Investigational
Matched Synonyms: … Cytochrome P450 isoform 2B1 gene transfected human embryonic kidney 293 cells encapsulated in polymeric …

(RP,SP)-O-(2R)-(1-PHENOXYBUT-2-YL)-METHYLPHOSPHONIC ACID CHLORIDE

Experimental
Matched Name: … (RP,SP)-O-(2R)-(1-PHENOXYBUT-2-YL)-METHYLPHOSPHONIC ACID CHLORIDE …

Candesartan cilexetil

Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone...
Approved
Matched Description: … RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and ... an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and ... Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and …
Matched Mixtures name: … CANDESARTAN PL 1A 8/12.5 ... CANDESARTAN PL 1A 8/12.5 ... CANDESARTAN PL 1A 8/12.5 …
Matched Categories: … Angiotensin II Antagonists and Diuretics …
Matched Products: … Candesartan 1A Pharma 4 mg - Tabletten ... Candesartan 1A Pharma 8 mg - Tabletten ... Candesartan 1A Pharma 16 mg - Tabletten …

AGIL-FA

Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype 5 carrying the gene for the human frataxin protein …

Rozrolimupab

Rozrolimupab is a recombinant polyclonal antibody consisting of 25 different anti-Rhesus D (RhD) antibodies to replace existing anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and the prevention of Hemolytic Disease of Newborns (HDN).
Investigational
Matched Synonyms: … Recombinant human antigen-specific polyclonal antibody (pAb) against RhD antigen expressed in Chinese …
Matched Description: … anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

AAV-AIPL

AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human AIPL1 gene. Developed by MeiraGTx, it is being investigated for the treatment of inherited retinal dystrophy due to defects in AIPL1 gene.
Investigational
Matched Synonyms: … adenovirus associated viral vector serotype 8 containing the human AIPL1 gene …
Matched Description: … AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human _AIPL1_ gene. …

PTR-01

Investigational
Matched Synonyms: … Recombinant human collagen alpha-1 (VII) chain homo-trimer (rC7) …

PBFT02

PBFT02 is a non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN gene encoding the protein progranulin.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN gene encoding …
Matched Description: … PBFT02 is a non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN …

Pegvorhyaluronidase alfa

Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Investigational
Matched Synonyms: … PEGylated recombinant human hyaluronidase PH20 ... -METHOXY-, AMIDE WITH HYALURONOGLUCOSAMINIDASE (HUMAN ISOENZYME PH20) ... HUMAN HYALURONIDASE PH-20 (HYALURONOGLUCOSAMINIDASE PH-20, SPERM ADHESION MOLECULE 1, EC 3.2.1.35) PRECURSOR …
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And …
Matched Categories: … Enzymes and Coenzymes …

Obexelimab

Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human CD19 antigen) (human-mus musculus monoclonal XMAB5871 heavy chain), disulfide ... with human-mus musculus monoclonal XMAB5871 light chain, dimer …

Anti-SARS-CoV-2 immunoglobulin

Hyperimmune immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and develop neutralizing antibodies. Anti-coronavirus immunoglobulin is derived from COVID-19 convalescent plasma(https://go.drugbank.com/drugs/DB15692) but contains more SARS-CoV-2 neutralizing antibodies than found in convalescent plasma (https://go.drugbank.com/drugs/DB15692) as the antibodies are highly purified and concentrated.[L27521, L27526]
Investigational
Matched Synonyms: … Anti-COVID-19 hyperimmune globulin (human) ... Human plasma-derived immune-globulin for Coronavirus …
Matched Description: … immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and ... [convalescent plasma](https://go.drugbank.com/drugs/DB15692) as the antibodies are highly purified and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 1176 - 1200 of 1382 in total