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Displaying drugs 12051 - 12075 of 14039 in total
Lysergic acid diethylamide
Debate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by experimental evidence. Some say HPPD is a manifestation of post-traumatic stress disorder, not related to the direct action of LSD...
Illicit
Investigational
Withdrawn
Matched Iupac: … (4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene …
Matched Categories: … Serotonin 5-HT2 Receptor Agonists …
Matched Categories: … Serotonin 5-HT2 Receptor Agonists …
Tetrodotoxin
An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order tetraodontiformes, which are eaten. The toxin causes paresthesia and paralysis through interference with neuromuscular conduction. Tetrodotoxin is being investigated by Wex Pharmaceuticals for the treatment of chronic and breakthrough pain in advanced cancer patients as...
Investigational
Matched Iupac: … 7,11}.0^{1,6}]tetradec-3-en-4-ium-9-olate ... (11S,13S)-3-amino-5,12,13,14-tetrahydroxy-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1^{ …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Felbinac
Experimental
Matched Iupac: … 2-{[1,1'-biphenyl]-4-yl}acetic acid …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Categories: … Non COX-2 selective NSAIDS …
Tofisopam
Tofisopam (marketed under brand names Emandaxin and Grandaxin) is a 2,3-benzodiazepine drug which is a benzodiazepine derivative. In contrast to classical 1,4-benzodiazepines, the compound does not bind to the benzodiazepine binding site of the gamma-aminobutyric acid receptor and its psychopharmacological profile differs from such compounds. Although Tofisopam is not approved...
Experimental
Matched Iupac: … 1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Piperine
Bioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders.
Investigational
Matched Iupac: … (2E,4E)-5-(2H-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Bamifylline
Bamifylline is a selective A1 adenosine receptor antagonist.
Experimental
Matched Iupac: … 8-benzyl-7-{2-[ethyl(2-hydroxyethyl)amino]ethyl}-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cepharanthine
Investigational
Matched Iupac: … {4,8}.0^{31,35}.0^{14,39}]nonatriaconta-1(34),3,8,10(39),16,18,21,23,25(36),31(35),32,37-dodecaene ... dimethoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.2^{16,19}.1^{3,10}.1^{21,25}.0^ …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Algenpantucel-L
Investigational
TSHA-101
Investigational
S-P-Nitrobenzyloxycarbonylglutathione
Experimental
Matched Name: … S-P-Nitrobenzyloxycarbonylglutathione …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-({hydroxy[(4-nitrophenyl)methoxy]methyl}sulfanyl …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-({hydroxy[(4-nitrophenyl)methoxy]methyl}sulfanyl …
Methylenedioxyethamphetamine
Experimental
Illicit
Matched Iupac: … [1-(2H-1,3-benzodioxol-5-yl)propan-2-yl](ethyl)amine …
Maduramicin
Maduramicin is an antiprotozoal agent used in veterinary medicine as prophylaxis against coccidiosis. It is a naturally occurring compound which was first isolated from the actinomycete, Actinomadura rubra.
Vet approved
Matched Iupac: … 2-[(2R,3S,4S,5R,6S)-6-[(1R)-1-[(2S,5R,7S,8R,9S)-2-[(2S,2'R,3'S,5R,5'R)-3'-{[(2R,4S,5S,6S)-4,5-dimethoxy ... ]-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]ethyl]-2-hydroxy-4,5-dimethoxy-3-methyloxan ... -6-methyloxan-2-yl]oxy}-5'-[(2S,3S,5R,6S)-6-hydroxy-3,5,6-trimethyloxan-2-yl]-2-methyl-[2,2'-bioxolane ... -2-yl]acetic acid amine …
Dexpramipexole
Dexpramipexole is under investigation in clinical trial NCT01511029 (Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate)).
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ulapualide A
Experimental
Matched Iupac: … (5S,9S,10S)-11-[(10S,16S,20S,21R,22S,24E)-16-hydroxy-22-methoxy-10,21-dimethyl-12,18-dioxo-3,7,19,27- ... tetraoxa-29,30,31-triazatetracyclo[24.2.1.1^{2,5}.1^{6,9}]hentriaconta-1(28),2(31),4,6(30),8,24,26(29 …
Ozarelix
Ozarelix has been used in trials studying the treatment of Prostate Cancer, Benign Prostatic Hypertrophy, and Benign Prostatic Hyperplasia (BPH).
Investigational
Matched Iupac: … (2R)-N-[(1S)-1-{[(2S)-5-carbamimidamido-1-[(2S)-2-{[(1R)-1-carbamoylethyl]carbamoyl}pyrrolidin-1-yl]- ... )-2-[(2R)-2-acetamido-3-(naphthalen-2-yl)propanamido]propanamido]-3-(pyridin-3-yl)propanamido]-3-hydroxy-N-methylpropanamido ... 1-oxopentan-2-yl]carbamoyl}pentyl]-6-(carbamoylamino)-2-[(2S)-2-[(2S)-2-[(2R)-2-[(2R)-3-(4-chlorophenyl ... ]-3-(4-hydroxyphenyl)propanamido]hexanamide …
N-BENZYLOXYCARBONYL-L-SERINE-BETALACTONE
Experimental
Matched Iupac: … (2S)-2-{[(benzyloxy)carbonyl]amino}propanoic acid …
Brequinar Analog
Experimental
Matched Iupac: … 2-{[1,1'-biphenyl]-4-yl}-6-fluoro-3-methylquinoline-4-carboxylic acid …
Zibotentan
Investigational
Matched Iupac: … N-(3-methoxy-5-methylpyrazin-2-yl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]pyridine-3-sulfonamide …
N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide
N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-l-prolinamide is a solid. This compound belongs to the alpha amino acid amides. These are amide derivatives of alpha amino acids. This medication targets the protein prothrombin.
Experimental
Matched Name: … N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide …
Matched Iupac: … (2S)-N-[(4-carbamimidoylphenyl)methyl]-1-(3-phenylpropanoyl)pyrrolidine-2-carboxamide …
Matched Description: … N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-l-prolinamide is a solid. …
Matched Iupac: … (2S)-N-[(4-carbamimidoylphenyl)methyl]-1-(3-phenylpropanoyl)pyrrolidine-2-carboxamide …
Matched Description: … N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-l-prolinamide is a solid. …
N-DODECANOYL-L-TYROSINE
Experimental
Matched Iupac: … (2S)-2-dodecanamido-3-(4-hydroxyphenyl)propanoic acid …
Adomiparin
Investigational
Astodrimer
Astodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups.
Investigational
Matched Salts cas: … 676271-69-5 …
Rigosertib
Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others.
Investigational
Matched Iupac: … 2-[(2-methoxy-5-{[(E)-2-(2,4,6-trimethoxyphenyl)ethenesulfonyl]methyl}phenyl)amino]acetic acid …
Reltecimod
Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections).
Investigational
Matched Iupac: … (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2R)-2-aminopropanamido]-3-hydroxypropanoyl ... ]pyrrolidin-2-yl]formamido}-4-(methylsulfanyl)butanamido]-4-methylpentanamido]-3-methylbutanamido]propanamido ... ]-3-(4-hydroxyphenyl)propanamido]-3-{[(1R)-1-carboxyethyl]carbamoyl}propanoic acid …
AS-8112
AS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5-HT3. It has been shown to exert potent antiemetic effects in animal studies and has been investigated for potential medical use.
Experimental
Matched Iupac: … 5-bromo-N-[(6R)-1-ethyl-4-methyl-1,4-diazepan-6-yl]-2-methoxy-4-(methylamino)benzamide …
Matched Description: … acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5- …
Matched Description: … acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5- …
Displaying drugs 12051 - 12075 of 14039 in total