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Displaying drugs 101 - 125 of 750 in total
Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Description: … A260621] As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and ... [A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17 ... cabazitaxel can more readily penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION ... JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION) ... Cabazred 60mg/1.5ml Concentrate And Solvent For Solution For Infusion …
Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Approved
Vet approved
Matched Synonyms: … beta-Methasone alcohol
Matched Description: … Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. ... [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally ... [A192444] Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity. …
Matched Mixtures name: … Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... betamethasone and mydriatics ... betamethasone and antiseptics ... betamethasone and antibiotics …
Matched Products: … Betnesol Eye and Ear Drops ... Betnesol Eye and Ear Drops 0.1% ... Pro-lene Glycol Cream - 0.05% …
Aluminum zirconium pentachlorohydrate is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing …
Matched Products: … Skin So Soft Soft and Sensual Anti-Perspirant Deodorant ... Skin So Soft Fresh and Smooth Moisturizing Hair Minimizing Anti-Perspirant Deodorant …
Eurotium amstelodami allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, aspergillus amsterdami …
Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Products: … Seborrheic Dermatitis and Psoriasis ... Seborrheic Dermatitis and Psoriasis Cream …
A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Approved
Investigational
Matched Description: … a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and
Matched Mixtures name: … Histamine DHCl 0.10 Percent and Menthol 2 Percent …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Hand and Wrist Pain Cream ... Australian Dream Hand and Wrist Pain ... MINTED LEAF Odorless Histamine DHCl Pain Relief and Hemp Extract …
Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and used as an expectorant . Since that time the agent has been a combination...
Approved
Investigational
Vet approved
Matched Description: … over-the-counter cough and cold products and is currently a widely available over-the-counter generic ... Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and ... continues to be one of very few - if not perhaps the only drug that is readily available and used as …
Matched Mixtures name: … Bronco Silen-DM ... Goyescas 7 Syrups Alcohol and Sugar Free Cough and Cold ... Up and Up Adult Cough and Cold …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … Up and Up Mucus Relief ... Up and Up mucus relief ... Mucus and Chest Congestion …
DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody and DNA alkylating cross-linking agent pyrrolo [2,1-c][1,4] benzodiazepine dimer ... THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal …
Matched Description: … DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell ... The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, …
TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Investigational
Matched Synonyms: … Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), Rapamycin and
Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal material. It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities, as well as UV-absorbing activity. Colloidal oatmeal...
Approved
Nutraceutical
Matched Description: … Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal ... It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. ... skin irritation and itching due to rashes, eczema, poison ivy, oak, sumac, or insect bites. …
Matched Mixtures name: … Dermavive Shower and Bath Oil …
Matched Products: … Skinfix Calm and Nourish Body ... Bite and Sting Soother ... Dry and Itchy Skin Relief Thayers …
Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Synonyms: … Trolamine salicylate …
Matched Name: … Trolamine salicylate …
Matched Description: … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid ... management of mild to moderate muscular and joint pains. ... temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and
Matched Products: … Up and Up Pain Relief Odorless ... Up and Up Odor-free Pain Relieving Cream ... Trolamine Salicylate …
Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and
Matched Categories: … Amino Acids, Peptides, and Proteins …
The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Matched Description: … and hemophilia A. ... vessel injury and stabilizing procoagulant factor VIII (FVIII). ... It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... von Willebrand factor and coagulation factor VIII in combination …
Matched Products: … IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND 3'-LTR/PO ... AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING ... , SELF-INACTIVATING LENTIVIRUS VECTOR THAT ENCODES HUMAN COLLAGEN TYPE VII ALPHA 1 (COL7A1) UNDER THE …
Matched Description: … It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen …
Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhibitors.
Approved
Investigational
Matched Description: … It is used to control bleeding in hemophilia A and B patients with inhibitors. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … FEIBA (Factor VIII Inhibitor Bypassing Activity) 25U/ml Powder and solvent for solution for infusion ... FEIBA (Factor VIII Inhibitor Bypassing Activity) 50U/ml Powder and solvent for solution for infusion …
Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat. It is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones . Undecylenic acid was...
Approved
Investigational
Matched Description: … relieves itching, burning, and irritation associated with the skin condition. ... isolated from the products of distillation of castor oil in 1877 via pyrolysis of ricinoleic acid, and ... undecylenate is an example of a topical antifungal agent that treats skin infections such as athlete’s foot and
Matched Mixtures name: … Foot and Body Powder ... Fungi Nail Toe and Foot MS ... Fungi Nail Toe and Foot MS …
Matched Products: … Fungi Nail Toe and Foot ... Fungi Nail Toe and Foot Pen ... Hongo Killer Nail and Fungus …
An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.
Experimental
Matched Products: … Tok and Care Sanitizer ... Dfenze HOCL Sanitizer and Disinfectant ... Belson Alcohol Free Hand Saniziter …
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Silver Bullet Suppository ... Up and Up Gentle Laxative …
Corn starch refers to the starch extracted from the corn grain that is commonly used as a food ingredient and chemical additive. Starch is any of a group of polysaccharides of the general formula (C6-H10-O5)n, composed of a long-chain polymer of glucose in the form of amylose and amylopectin. Starch...
Approved
Nutraceutical
Matched Description: … starch refers to the starch extracted from the corn grain that is commonly used as a food ingredient and ... the general formula (C6-H10-O5)n, composed of a long-chain polymer of glucose in the form of amylose and ... Corn starch may be added in some food products as a thickening agent or anti-caking agent, and is sometimes …
Matched Products: … Soothe and Cool Non-Caking Body ... Lotrimin Daily Sweat and Odor Control …
Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Description: … It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does ... approved product by the FDA containing only carbidopa was developed by Amerigens Pharmaceuticals Ltd and
Matched Mixtures name: … Carbidopa and Levodopa ... Carbidopa and Levodopa ... Carbidopa and Levodopa …
Matched Products: … Carbidopa and Levodopa ... Carbidopa and levodopa …
Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for...
Approved
Investigational
Matched Products: … Spy Agent Green Kit for Advanced Imaging Modality (aim) and Pinpoint ... Spy Agent Green Lymphatics Kit for Advanced Imaging Modality (aim) and Pinpoint …
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY, BISPECIFIC ... -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND
Matched Description: … arm comprising a heavy and light chain. ... It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each ... Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Synonyms: … (−)-m-hydroxy-α-(methylaminomethyl)benzyl alcohol
Matched Description: … alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and
Matched Mixtures name: … ALCADOL®GRIPA ... Sildec PE ... Sildec PE DM …
Matched Categories: … Alcohols ... Amino Alcohols ... Adrenergic and Dopaminergic Agents ... Mydriatics and Cycloplegics ... Decongestants and Antiallergics …
Matched Products: … Up and Up Sinus PE ... CareOne Cold and Sinus ... Up and Up nasal decongestant PE …
Investigational
Matched Synonyms: … engager antibody with a single chain fc moiety that binds to b cell maturation antigen surface receptor and
Displaying drugs 101 - 125 of 750 in total