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Displaying drugs 101 - 125 of 655 in total

Potassium acetate

Approved
Investigational
Matched Mixtures name: … Normosol-M and Dextrose ... Plasma-lyte 56 and Dextrose ... Normosol-M and Dextrose …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …

Calcipotriol

Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Approved
Matched Mixtures name: … Calcipotriene 0.005% / Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 2% ... Calcipotriene and Betamethasone Dipropionate ... Calcipotriene and Betamethasone Dipropionate …
Matched Categories: … Vitamin D and Analogues ... Skin and Mucous Membrane Agents …

Methenamine

Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Approved
Vet approved
Matched Description: … for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid …
Matched Mixtures name: … Methenamine and Sodium Salicylate ... Methenamine and Sodium Salicylate (nsaid) ... Disinfectant(Model III)Sanitizer Hand And Surface …
Matched Categories: … sodium salicylate and methenamine ... Genito Urinary System and Sex Hormones …

Finasteride

Finasteride is a synthetic 4-azasteroid compound and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). It works in a similar fashion as dutasteride, which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. Finasteride is an orally active drug...
Approved
Matched Description: … Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase ... [L6244] Finasteride is commonly marketed under the brand names Propecia and Proscar to be used aloneo ... first approved by the FDA in 1992 for the treatment of benign prostatic hyperplasia to improve symptoms and …
Matched Mixtures name: … Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% ... Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% / Tretinoin 0.025% …
Matched Categories: … doxazosin and finasteride ... alfuzosin and finasteride ... finasteride and tadalafil ... Skin and Mucous Membrane Agents ... Genito Urinary System and Sex Hormones …

Betamethasone phosphate

Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible betamethasone to agonize glucocorticoid receptors. Betamethasone provides greater anti-inflammatory activity than prednisolone with less sodium and water retention. Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.
Approved
Vet approved
Matched Iupac: … 1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethoxy}phosphonic acid …
Matched Description: … and water retention. ... [L11994] Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.[L11994] ... [L11994] Betamethasone provides greater anti-inflammatory activity than [prednisolone] with less sodium …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Ceftriaxone

Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Iupac: … tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … meninges[A215582], eyes[A215647], and inner ear[A215627]. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the ... Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins …
Matched Salts name: … Ceftriaxone sodium …
Matched Products: … Ceftriaxone and Dextrose ... Ceftriaxone Sodium ... CEFTRIAXONE SODIUM …

Novobiocin

Novobiocin is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189) Novobiocin sodium, a salt form of novobiocin, was initially approved in September 1964...
Approved
Investigational
Vet approved
Withdrawn
Matched Description: … Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. ... (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189) Novobiocin sodium, a salt form ... of novobiocin, was initially approved in September 1964 and was indicated for the treatment of serious …
Matched Salts name: … Novobiocin sodium …
Matched Categories: … Nucleic Acid Synthesis Inhibitors …

Treprostinil

Treprostinil is a stable tricyclic analogue of prostacyclin that promotes the vasodilation of pulmonary and systemic arterial vascular beds and the inhibition of platelet aggregation.[L41855,L41860,L41865] It reduces symptoms in patients with pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease.[L41855,L41860] The first agent approved for the treatment...
Approved
Investigational
Matched Iupac: … 9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H,2H,3H,3aH,4H,9H,9aH-cyclopenta[b]naphthalen-5-yl]oxy}acetic acid …
Matched Description: … systemic arterial vascular beds and the inhibition of platelet aggregation. ... is a stable tricyclic analogue of prostacyclin[A248770] that promotes the vasodilation of pulmonary and ... [L41855,L41860,L41865] It reduces symptoms in patients with pulmonary arterial hypertension (PAH) and …
Matched Salts name: … Treprostinil sodium …
Matched Categories: … Blood and Blood Forming Organs …

Procainamide

A derivative of procaine with less CNS action.
Approved
Matched Categories: … Benzamides and benzamide derivatives ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …

Hydrochlorothiazide

Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459] Hydrochlorothiazide was granted FDA...
Approved
Vet approved
Matched Description: … [A185138] It is indicated to treat edema and hypertension. ... [A185138] Many combination products are available containing hydrochlorothiazide and angiotensin converting …
Matched Mixtures name: … Fosinopril Sodium and Hydrochlorothiazide ... Fosinopril Sodium and Hydrochlorothiazide ... Fosinopril Sodium and Hydrochlorothiazide …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... hydrochlorothiazide and potassium ... aliskiren and hydrochlorothiazide ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Losartan Potassium and Hydrochlorothiazide …

Quinethazone

Quinethazone, marketed as Hydromox, is a thiazide diuretic indicated for hypertension. Patients may experience adverse reactions such as dizziness, dry mouth, nausea, and hypokalemia.
Approved
Matched Description: … Patients may experience adverse reactions such as dizziness, dry mouth, nausea, and hypokalemia. …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... quinethazone and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Drospirenone

Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Description: … [L7973] Most recently, it was approved by both Health Canada and the FDA in combination with [Estetrol ... ,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to control acne and ... during the postpartum period, and this should be considered when assessing potential risks of hormonal …
Matched Mixtures name: … Drospirenone and Ethinyl Estradiol ... Drospirenone and Ethinyl Estradiol ... Drospirenone and Ethinyl Estradiol …
Matched Categories: … drospirenone and estetrol ... drospirenone and estrogen ... drospirenone and ethinylestradiol ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …

Riluzole

A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Approved
Investigational
Matched Description: … A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong …
Matched Categories: … Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists …

Flavin mononucleotide

A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.
Approved
Investigational
Matched Iupac: … -{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}phosphonic acid …
Matched Description: … It is the principal form in which RIBOFLAVIN is found in cells and tissues. …
Matched Mixtures name: … Multi Vitamin and Fluoride ... Somarexin and C 1000 ... Multi Vitamin and Fluoride …
Matched Salts name: … Riboflavin 5'-phosphate sodium anhydrous ... Riboflavin sodium phosphate ... Riboflavin-5'-phosphate sodium salt dihydrate …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …

Pregabalin

Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects...
Approved
Investigational
Matched Iupac: … (3S)-3-(aminomethyl)-5-methylhexanoic acid …
Matched Description: … Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter ... [A173995] It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other ... [A187190,L7066] Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Flavin adenine dinucleotide

A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) Flavin adenine dinucleotide is approved for use in Japan under the trade name Adeflavin as an ophthalmic treatment for vitamin B2 deficiency.
Approved
Matched Iupac: … -2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}(hydroxy)phosphoryl)oxy]phosphinic acid …
Matched Description: … ., D-amino acid oxidase and L-amino acid oxidase. ... A condensation product of riboflavin and adenosine diphosphate. …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …

Potassium

Potassium is an essential nutrient, like Calcium and Magnesium. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans. Many conditions and diseases interfere with normal body potassium balance, and underconsumption of potassium is one example. Hypokalemia (low potassium) or hyperkalemia (high potassium)...
Approved
Experimental
Matched Description: … dextrose and sodium chloride. ... [A186928] Many conditions and diseases interfere with normal body potassium balance, and underconsumption ... They are available in an assortment of tablet, injection, and other forms, depending on the setting and …
Matched Mixtures name: … CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET ... Potassium and Iodine Tab ... Revit Multi-vitamins and Minerals …
Matched Categories: … mefruside and potassium ... clopamide and potassium ... clofenamide and potassium ... furosemide and potassium ... quinethazone and potassium …

Trichlormethiazide

A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
Approved
Vet approved
Matched Categories: … Sodium Chloride Symporter Inhibitors ... trichlormethiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... trichlormethiazide and potassium-sparing agents …

Daptomycin

Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Iupac: … carbamoyl}-3-[(2R)-3-carbamoyl-2-[(2S)-2-decanamido-3-(1H-indol-3-yl)propanamido]propanamido]propanoic acid …
Matched Description: … covalently bonded to decanoic acid. ... -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE). ... with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Daptomycin in Sodium Chloride …

Tazobactam

Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. It is combined with Piperacillin and Ceftolozane for the treatment of a variety of bacterial infections. Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved...
Approved
Matched Iupac: … 4,4,7-trioxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections ... ventilator-associated bacterial pneumonia, which are significant causes of morbidity and mortality in ... , ceftolozane-tazobactam was approved by the FDA for treating hospital-acquired bacterial pneumonia and …
Matched Mixtures name: … PIPERACILLIN SODIUM and TAZOBACTAM SODIUM ... PIPERACILLIN SODIUM and TAZOBACTAM SODIUM ... PIPERACILLIN SODIUM and TAZOBACTAM SODIUM …
Matched Salts name: … Tazobactam sodium …

Encainide

All drug products containing encainide hydrochloride. Encainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack. The manufacturer of Enkaid capsules voluntarily withdrew the product from the US market on December 16, 1991.
Approved
Investigational
Withdrawn
Matched Categories: … Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …

Sulfamethazine

A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
Approved
Investigational
Vet approved
Matched Salts name: … Sulfamethazine sodium …
Matched Categories: … Sulfonamides and trimethoprim ... sulfadimidine and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Olsalazine

Olsalazine is an aminosalicylate and a prodrug of mesalamine (5-aminosalicylic acid, 5-ASA). It was first developed for delivering mesalamine to the colon without the use of sulfapyridine. Olsalazine comprises two mesalamine molecules joined by an azo bridge, which is cleaved in the colon. Olsalazine is an anti-inflammatory agent that works...
Approved
Matched Iupac: … 5-[(1E)-2-(3-carboxy-4-hydroxyphenyl)diazen-1-yl]-2-hydroxybenzoic acid …
Matched Description: … Olsalazine is an aminosalicylate and a prodrug of [mesalamine] (5-aminosalicylic acid, 5-ASA). ... , subsequently reducing the production of pro-inflammatory factors like prostaglandin and leukotriene ... [A257078] Olsalazine is an anti-inflammatory agent that works by inhibiting cyclooxygenase and lipoxygenase …
Matched Salts name: … Olsalazine sodium …
Matched Categories: … Alimentary Tract and Metabolism …

Inositol

Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate. These molecules have structural...
Approved
Investigational
Withdrawn
Matched Description: … of corn kernels by precipitation and hydrolysis of crude phytate. ... These molecules have structural similarities to glucose and are involved in cellular signaling. ... Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract …
Matched Mixtures name: … B-complex With Vitamin C, Biotin, Folic Acid ... Niacin 500 Mg and Inositol ... Revit Multi-vitamins and Minerals …
Matched Categories: … Alimentary Tract and Metabolism …

Topiramate

Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Description: … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. ... topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and …
Matched Salts name: … Topiramate sodium …
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
Displaying drugs 101 - 125 of 655 in total