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Displaying drugs 101 - 125 of 9336 in total

Deferiprone

Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired....
Approved
Matched Description: … Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload ... FDA approved on October 14, 2011. …

Testosterone enanthate

Testosterone enanthate is an esterified variant of testosterone that comes as an injectable compound with a slow-release rate. This slow release is achieved by the presence of the enanthate ester functional group attached to the testosterone molecule. This testosterone derivative was first approved on December 24, 1953. In 2017, about...
Approved
Matched Description: … Testosterone enanthate is an esterified variant of testosterone that comes as an injectable compound ... This slow release is achieved by the presence of the enanthate ester functional group attached to the ... As recent as 1 October 2018, the US FDA approved Antares Pharma Inc.' …

Adenosine phosphate

Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.
Approved
Investigational
Nutraceutical
Withdrawn
Matched Description: … Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified ... the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an …

Resorcinol

Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses, and warts. It exerts a keratolytic activity. Resorcinol works...
Approved
Matched Description: … It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin …

Luliconazole

Luliconazole is a topical antifungal agent that acts by unknown mechanisms but is postulated to involve altering the synthesis of fungi cell membranes. It was approved by the FDA (USA) in November 2013 and is marketed under the brand name Luzu. Luliconazole is also approved in Japan.
Approved
Matched Description: … Luliconazole is a topical antifungal agent that acts by unknown mechanisms but is postulated to involve ... Luliconazole is also approved in Japan. ... It was approved by the FDA (USA) in November 2013 and is marketed under the brand name Luzu. …

Protamine sulfate

Since it's earliest discovery in salmon rine sperm heads in the late 1800's to its formal introduction via US FDA approval in 1939, protamine sulfate has occupied an important therapeutic niche as perhaps the only viable option for reversing the anticoagulant effect of heparin use for over 77 years [A174778,...
Approved
Matched Description: … The agent elicits this heparin reversal predominantly via the formation of an inactive complex between ... late 1800's to its formal introduction via US FDA approval in 1939, protamine sulfate has occupied an ... sulfate use is clinically considered, careful consideration must be given as to whether the use of the agent …
Matched Categories: … Heparin Reversal Agent …

Mitoxantrone

An anthracenedione-derived antineoplastic agent.
Approved
Investigational
Matched Description: … An anthracenedione-derived antineoplastic agent. …

Eucalyptus oil

Eucalyptus oil is a distilled oil derived from the leaves of the tree Eucalyptus. It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on the immune response. It is also shown to exhibit antibacterial activity against some bacterial species and cough suppressant actions....
Approved

Anagrelide

Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms. It is an oral imidazoquinazoline that was first approved for use in the US in 1997. It appears to carry a better response rate than other thrombocythemia treatments (e.g....
Approved
Matched Description: … [L14153] It is an oral imidazoquinazoline that was first approved for use in the US in 1997. ... Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat …

Timolol

Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the FDA in 1978. This drug is marketed by several manufacturers...
Approved
Matched Description: … [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management ... [L6727] Timolol was first approved by the FDA in 1978. ... Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular …

Vanillyl butyl ether

Vanillyl butyl ether is an ether of monohydroxybenzoic acid. It is added to food products as a flavoring agent. It is also present in cosmetics and personal care products as a fragrance ingredient, oral care agent, hair conditioning agent, and warming or cooling agent.
Approved
Matched Description: … Vanillyl butyl ether is an ether of monohydroxybenzoic acid. ... , hair conditioning agent, and warming or cooling agent. ... It is added to food products as a flavoring agent. …

Gadofosveset trisodium

Gadofosveset trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA), which is a non-invasive way of imaging blood vessels. The agent allows for the vascular system to be imaged more clearly by the MRA. In this way, gadofosveset trisodium is used to help diagnose certain disorders of the...
Approved
Matched Description: … Gadofosveset trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA) ... The agent allows for the vascular system to be imaged more clearly by the MRA. …
Matched Categories: … Paramagnetic Contrast Agent ... Gadolinium-based Contrast Agent …

Radium Ra 223 dichloride

Radium Ra 223 Dichloride is a radiopharmaceutical containing the radioisotope radium-223 that emits short range but high linear energy alpha particles. As a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas of high bone turnover as seen in bone metastases. It was...
Approved
Investigational
Matched Description: … It was first approved by the FDA in May 2013 and is currently marketed under the brand name Xofigo, which …
Matched Categories: … Radioactive alpha-Particle Emitting Therapeutic Agent …

Brilliant blue G

Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of the eye during ophthalmic procedures.[A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries that require high levels of visual accuracy. Brilliant blue G, like its name, imparts...
Approved
Matched Description: … It was approved by the FDA for ophthalmic use on December 20, 2019.[L10830] ... Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) …
Matched Categories: … Disclosing Agent …

Eravacycline

Eravacycline, known as Xerava by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic of the tetracycline class with activity against clinically significant gram-negative, gram-positive aerobic, and facultative bacteria. This includes most of those bacteria resistant to cephalosporins, fluoroquinolones, β-lactam/β-lactamase inhibitors, multidrug-resistant strains, and carbapenem-resistant Enterobacteriaceae, and the majority of anaerobic...
Approved
Investigational
Matched Description: … It was first approved by the FDA on August 27, 2018 [L4540]. …

Galactose

Galactose has been used in trials studying the treatment and diagnosis of Hepatitis C, Hepatic Cancer, Wilsons Disease, Diabetic Macular Oedema, and Focal Segmental Glomerulosclerosis, among others. There are even proposals for its use in accelerating senescence in mice, rats, and Drosophila, for its association with ovarian cancer, or even...
Approved
Investigational
Matched Description: … predominantly used as a pathway to generate glucose fuel for the human body, galactose is involved as an …

Tacrine

A centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. Tacrine has been discontinued for the United States market.
Approved
Investigational
Withdrawn

Benzalkonium

Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. Benzalkonium is more commonly contained in consumer products in its salt form, benzalkonium chloride [FDA Label]. This salt is used in a great variety of international pharmaceutical products such...
Approved
Investigational
Matched Description: … agent [L1806]. ... is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent ... When used as an ingredient in antiseptic and disinfectant products however, it is an active antimicrobial …
Matched Products: … Youke an ... BZK Agent Sanitizer ... Antiseptic Hand Sanitizer Alcohol Free Valencia Group …

Chloroxylenol

Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Description: … Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin …

Streptokinase

Streptokinase, is a sterile, purified preparation of a bacterial protein elaborated by group C (beta) -hemolytic streptococci.
Approved
Investigational
Matched Description: … Streptokinase, is a sterile, purified preparation of a bacterial protein elaborated by group C (beta) …

Ioversol

Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues. Iodine has a high atomic density, which gives it the ability to attenuate X-rays. The intravascular administration of iodine compounds, such as ioversol, enhances...
Approved
Matched Description: … [L41780] Ioversol is a highly hydrophilic agent considered to be generally safe[L41790]; however, serious ... [L41780] Ioversol was approved by the FDA in 1989 and is currently indicated for computed tomographic …
Matched Categories: … Radiographic Contrast Agent …

Tofacitinib

Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate....
Approved
Investigational
Matched Description: … Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling ... It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately …

Futibatinib

Futibatinib is an inhibitor of Fibroblast Growth Factor receptor (FGFR), which comprises a group of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and survival. FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated FGFR signalling pathways are observed...
Approved
Investigational
Matched Description: … Futibatinib is an inhibitor of Fibroblast Growth Factor receptor (FGFR), which comprises a group of receptor ... [A253193,A253198] As a novel inhibitor of FGFR, futibatinib was first approved by the FDA in September …

Olutasidenib

Olutasidenib (FT-2102) is a selective and potent isocitrate dehydrogenase-1 (IDH1) inhibitor approved by the FDA in December 2022.[L44256,L44261] It is indicated for the treatment of relapsed or refractory acute myeloid leukemia (AML) in patients with a susceptible IDH1 mutation as determined by an FDA-approved test. IDH1 mutations are common in...
Approved
Investigational
Matched Description: … FDA-approved test. ... refractory acute myeloid leukemia (AML) in patients with a susceptible IDH1 mutation as determined by an ... intrahepatic cholangiocarcinoma, chondrosarcoma, and myelodysplastic syndromes (MDS), and they lead to an …

Nicotinamide

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Description: … An important compound functioning as a component of the coenzyme NAD. …
Matched Mixtures name: … Kanga-B Vitamin B Group + C …
Matched Products: … An Adc Sp Intensive Moisture Essence …
Displaying drugs 101 - 125 of 9336 in total