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Displaying drugs 101 - 125 of 14348 in total

Calcifediol

The major circulating metabolite of vitamin D3 (cholecalciferol). It is produced in the liver and is the best indicator of the body's vitamin D stores. It is effective in the treatment of rickets and osteomalacia, both in azotemic and non-azotemic patients. Calcifediol also has mineralizing properties.
Approved
Nutraceutical
Matched Description: … It is effective in the treatment of rickets and osteomalacia, both in azotemic and non-azotemic patients ... It is produced in the liver and is the best indicator of the body's vitamin D stores. …
Matched Categories: … Diet, Food, and Nutrition ... Vitamin D and Analogues ... Alimentary Tract and Metabolism ... Sex Hormones and Insulins …

Methylprednisolone

Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives ... Ophthalmological and Otological Preparations …

Testosterone enanthate

Testosterone enanthate is an esterified variant of testosterone that comes as an injectable compound with a slow-release rate. This slow release is achieved by the presence of the enanthate ester functional group attached to the testosterone molecule. This testosterone derivative was first approved on December 24, 1953. In 2017, about...
Approved
Matched Description: … The majority of the prescriptions written were for injectable (66%) and topical (32%) testosterone products ... therapy, this innovative formulation removes transfer concerns commonly associated with testosterone gels and …
Matched Categories: … Testosterone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Desogestrel

Desogestrel, a prodrug, is a third generation progestogen and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada. It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological...
Approved
Matched Description: … family which was largely used in Europe before being approved in the US and Canada. ... Desogestrel, a prodrug, is a third generation progestogen[A176315] and hence, a member of the gonane ... [A176339] It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent …
Matched Mixtures name: … Desogestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Desogestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Desogestrel and Ethinyl Estradiol …
Matched Categories: … desogestrel and estrogen ... desogestrel and ethinylestradiol ... desogestrel and ethinylestradiol ... Genito Urinary System and Sex Hormones ... Combination Contraceptives (with Estrogen and derivatives) …

Benazepril

Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor .
Approved
Investigational
Matched Description: … Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and …
Matched Mixtures name: … Benazepril and Hydrochlorothiazide ... Benazepril and Hydrochlorothiazide ... Benazepril and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Diuretics ... benazepril and diuretics ... benazepril and amlodipine ... ACE Inhibitors and Calcium Channel Blockers …

Triamterene

Triamterene (2,4,7-triamino-6-phenylpteridine) is a potassium-sparing diuretic that is used in the management of hypertension. It works by promoting the excretion of sodium ions and water while decreasing the potassium excretion in the distal part of the nephron in the kidneys by working on the lumenal side. Since it acts on...
Approved
Matched Description: … Triamterene is a weak antagonist of folic acid, and a photosensitizing drug. ... [L6163] Triamterene was approved by the Food and Drug Administration in the U.S. in 1964. ... is approved for use with other diuretics to enhance diuretic and potassium-sparing effects. …
Matched Mixtures name: … Triamterene and Hydrochlorothiazide ... Triamterene and Hydrochlorothiazide ... Triamterene and Hydrochlorothiazide …

Diphenoxylate

A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. This medication is classified as a Schedule V under the Controlled Substances Act...
Approved
Illicit
Matched Description: … Its unesterified metabolite difenoxin has similar properties and is used similarly. ... Administration (FDA) and the DEA in the United States when used in preparations. ... This medication is classified as a Schedule V under the Controlled Substances Act by the Food and Drug …
Matched Mixtures name: … Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hcl and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate …
Matched Categories: … Alimentary Tract and Metabolism …

Piperacillin

Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Approved
Matched Mixtures name: … Piperacillin and Tazobactam ... Piperacillin and Tazobactam ... Piperacillin and Tazobactam …

Dextroamphetamine

Dextroamphetamine is the dextrorotatory enantiomer of amphetamine . Dextroamphetamine was approved by the FDA in 2001 for the treatment of attention deficit hyperactivity disorder[L6010,Label].
Approved
Illicit
Matched Mixtures name: … Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine ... Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine ... Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …

Atropine

Atropine is an alkaloid originally synthesized from Atropa belladonna. It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active.[A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. Oral atropine is only available...
Approved
Vet approved
Matched Description: … , subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. ... It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active ... [A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous …
Matched Mixtures name: … Diphenoxylate Hcl and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate …
Matched Categories: … pralidoxime and atropine ... Alimentary Tract and Metabolism ... atropine and psycholeptics ... Mydriatics and Cycloplegics ... Belladonna and Derivatives, Plain …

Triprolidine

First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.
Approved
Matched Description: … It is a component of cough and cold medicines. It may cause drowsiness. ... First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. …
Matched Mixtures name: … and Flu Clear and Cool ... Mucus DM Fast Max Day Cold and Flu and Night Cold and Flu ... Mucinex Fast-Max Cold and Flu and Mucinex NightShift Cold and Flu …

Amoxicillin

Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … Amoxicillin and clavulanate potassium ... Amoxicillin and clavulanate potassium ... Amoxicillin and clavulanate potassium …
Matched Categories: … Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... omeprazole, amoxicillin and rifabutin ... omeprazole, amoxicillin and metronidazole ... vonoprazan, amoxicillin and clarithromycin …

Dexamethasone

Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Description: … dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and ... L10701] Developed in 1957, it is structurally similar to other corticosteroids like [hydrocortisone] and ... Dexamethasone reduced deaths by approximately one third in patients requiring ventilation and by one …
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Dexamethasone ... Neomycin and Polymyxin B Sulfates and Dexamethasone ... Neomycin and Polymyxin B Sulfates and Dexamethasone …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... dexamethasone and antibiotics ... dexamethasone and antiinfectives ... dexamethasone and antiinfectives …

Neomycin

Neomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of Streptomyces fradiae. Neomycin is a complex comprised of three components, neomycin A, B, and C. Neomycin B, also known as framycetin, is the most active component of the complex and neomycin C is the isomer...
Approved
Vet approved
Matched Description: … [A175042] Neomycin is active against both gram-positive and gram-negative organisms and mediates its ... [L11979] Neomycin is a complex comprised of three components, neomycin A, B, and C. ... preparations for use in the treatment of inflammatory conditions and infections in the eye. …
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Bacitracin Zinc ... Neomycin and Polymyxin B Sulfates and Dexamethasone ... Neomycin and Polymyxin B Sulfates and Hydrocortisone …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Ophthalmological and Otological Preparations ... Antiinfectives and Antiseptics for Local Oral Treatment …

Tramadol

Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is considered...
Approved
Investigational
Matched Description: … of and response to pain. ... such as [duloxetine] and [venlafaxine]. ... ) that is structurally related to [codeine] and [morphine]. …
Matched Mixtures name: … Tramadol HCl and Acetaminophen ... Tramadol Hydrochloride and Acetaminophen ... Tramadol Hydrochloride and Acetaminophen …
Matched Categories: … tramadol and celecoxib ... tramadol and paracetamol ... tramadol and dexketoprofen …

Ampicillin

Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Approved
Vet approved
Matched Mixtures name: … Ampicillin and Sulbactam ... Ampicillin and Sulbactam ... Ampicillin and Sulbactam …

Atenolol

Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize. Beta-blockers quickly became popular in clinical use and where subsequently investigated for...
Approved
Matched Description: … use in myocardial infarction, arrhythmias, and hypertension during the 1960s. ... [A178429] Beta-blockers quickly became popular in clinical use and where subsequently investigated for ... widely prescribed beta blockers, evidence suggests atenolol may not significantly reduce mortality, and …
Matched Mixtures name: … Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone …
Matched Categories: … atenolol and thiazides ... atenolol and nifedipine ... atenolol and other diuretics ... Beta Blocking Agents and Thiazides ... atenolol, thiazides and other diuretics …

Esterified estrogens

Esterified estrogens contain a mixture of estrogenic substances; the principle component is estrone. Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90%. Esterified estrogens are a man-made mixture of estrogens that are used to treat symptoms of...
Approved
Matched Description: … It is being also for the prevention and treatment of osteoporosis. ... Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that …
Matched Mixtures name: … Esterified Estrogens and Methyltestosterone ... Esterified Estrogens and Methyltestosterone ... Esterified Estrogens and Methyltestosterone …

Promethazine

Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171] Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Description: … allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and …
Matched Mixtures name: … Meperidine Hcl and Promethazine Hcl ... Promethazine HCl and Codeine Phosphate ... Promethazine Hydrochloride and Codeine Phosphate …
Matched Categories: … prednisolone and promethazine ... Miscellaneous Anxiolytics Sedatives and Hypnotics …

Antipyrine

An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Approved
Investigational
Matched Description: … An analgesic and antipyretic that has been given by mouth and as ear drops. …
Matched Mixtures name: … Antipyrine and Benzocaine ... Antipyrine and Benzocaine ... Antipyrine and Benzocaine …
Matched Categories: … Analgesics and Anesthetics …

Sulbactam

Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.
Approved
Matched Description: … Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. …
Matched Mixtures name: … Ampicillin and Sulbactam ... Ampicillin and Sulbactam ... Ampicillin and Sulbactam …

Chlorthalidone

Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule...
Approved
Matched Description: … Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management ... effect is under debate, however, it is thought that increased diuresis results in decreased plasma and ... Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through …
Matched Mixtures name: … Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone …
Matched Categories: … chlortalidone and potassium ... chlortalidone and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …

Fosinopril

Fosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and...
Approved
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and ... to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and …
Matched Mixtures name: … Fosinopril Sodium and Hydrochlorothiazide ... Fosinopril Sodium and Hydrochlorothiazide ... Fosinopril Sodium and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Diuretics ... fosinopril and diuretics ... Amino Acids, Peptides, and Proteins …

Prilocaine

A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Mixtures name: … Lidocaine and Prilocaine ... Lidocaine and Prilocaine ... Lidocaine and Prilocaine …

Tenofovir disoproxil

Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (nRTIs). This drug is prescribed in combination with other drugs for the management of HIV infection as well as for...
Approved
Investigational
Matched Mixtures name: … Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Tenofovir and prodrugs ... lamivudine and tenofovir disoproxil ... tenofovir disoproxil and emtricitabine ... lamivudine, tenofovir disoproxil and efavirenz ... lamivudine, tenofovir disoproxil and doravirine …
Displaying drugs 101 - 125 of 14348 in total