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Displaying drugs 1251 - 1275 of 1607 in total
A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Approved
Vet approved
Matched Description: … A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of …
Matched Mixtures name: … L-OMBRIX-DUET ... L-OMBRIX-DUET …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Products: … L-OMBRIX …
Investigational
Matched Synonyms: … DNA (synthetic vaccinia virus strain MVA human papillomavirus-targeted) …
Investigational
Matched Synonyms: … Endoplasmin (human tumor rejection antigen 1) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Chimeric M-T412 (human-murine) IgG monoclonal anti-CD4 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
INZ-701 is an enzyme replacement therapy under development with the intention to be used for the treatment of calcification disorders of the circulatory system, bones, and kidneys.
Investigational
Matched Synonyms: … Recombinant human ectonucleotide pyrophosphatase/phosphodiesterase 1 fused to the Fc fragment of IGG1 …
Matched Description: … intention to be used for the treatment of calcification disorders of the circulatory system, bones, and
PRX-ASL is an intracellular enzyme replacement therapy designed to replace the missing or defective enzyme in patients with argininosuccinate lyase deficiency.
Investigational
Matched Synonyms: … Modified messenger ribonucleic acid encoding human argininosuccinate lyase enzyme encapsulated into lipid …
Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant region (IgG2-Fc).[A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).
Investigational
Matched Synonyms: … RECOMBINANT HUMAN INTERLEUKIN-22 IGG2-FC ... F-652 (RECOMBINANT FUSION PROTEIN CONSISTING OF TWO HUMAN INTERLEUKIN-22 (IL-22) MOLECULES LINKED TO …
Matched Description: … recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Experimental
Matched Synonyms: … α-L-Fuc-(1→2)-β-D-Gal-(1→3)-β-D-GlcNAc ... alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-beta-D-GlcpNAc …
Matched Name: … Human blood group H type 1 trisaccharide …
Investigational
Matched Name: … Human autologous bone marrow derived osteoblastic cells …
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor) ... Human Factor XIII (A2) homodimer (allele F13A*1B), recombinant DNA origin …
Matched Description: … then isolated, the human form is isolated from pooled human plasma. ... ) include [DB12909], which is a purified endogenous (human) form of coagulation factor XIII. ... and maintenance of hemostasis [A18581]. …
Matched Categories: … Blood and Blood Forming Organs …
Experimental
Matched Synonyms: … 6-hydroxy-L-norleucine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … N2-Acetyl-N-[(2S)-5-chloro-3-oxo-1-phenyl-2-pentanyl]-L-alaninamide …
Matched Name: … (2S) N-acetyl-L-alanyl-αL-phenylalanyl-chloroethylketone …
Racemetyrosine is under investigation in clinical trial NCT03512756 (A Randomized Phase 2/3 Multi-center Study of SM-88 in Patients With Metastatic Pancreatic Cancer).
Investigational
Matched Synonyms: … D,L-metyrosine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. Since glatiramer acetate is a heterogeneous drug, there is limited information about its physicochemical properties. Originally, glatiramer acetate was designed as a...
Approved
Investigational
Matched Synonyms: … (T,G)-A-L
Matched Description: … [A248870] Along with [human interferon beta], [teriflunomide], and [dimethyl fumarate], glatiramer acetate ... , and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. ... Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.
Approved
Matched Synonyms: … L-Gulitol …
Matched Description: … It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for ... Sorbitol occurs naturally and is also produced synthetically from glucose. …
Matched Mixtures name: … Cleanse Gut And Colon ... INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion) …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Diet, Food, and Nutrition ... Indicators and Reagents ... Blood Substitutes and Perfusion Solutions …
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Synonyms: … (8S-cis)-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy ... 3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside …
Matched Description: … Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. ... [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain ... generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … RIBODOXO L 10 ... RIBODOXO L 50 …
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Synonyms: … L-noradrenaline ... L-Norepinephrine …
Matched Description: … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... It is also found in plants and is used pharmacologically as a sympathomimetic. ... Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse …
Matched Categories: … Epinephrine and similars ... Adrenergic and Dopaminergic Agents ... Alpha-and Beta-adrenergic Agonists …
Matched Products: … Levophed Liq IV 1.0mg/ml …
Experimental
Matched Name: … N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ALANINE …
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (226-PROLINE), ANTI-(HUMAN MANNAN-BINDING LECTIN-ASSOCIATED SERINE PROTEASE 2) (HUMAN ... MONOCLONAL OMS721 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL OMS721 .LAMBDA. ... MANNAN-BINDING LECTIN SERINE PROTEASE 2 (MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASE 2, EC=3.4.21.104) HUMAN
Matched Description: … uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … 4R-Fluoro-N6-ethanimidoyl-L-lysine …
Experimental
Matched Name: … D-phenylalanyl-N-benzyl-L-prolinamide …
Experimental
Matched Name: … GLYCYLALANYL-N-2-NAPHTHYL-L-PROLINEAMIDE …
A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.
Experimental
Matched Synonyms: … L-tyrosyl-3-mercapto-D-valylglycyl-L-phenylalanyl-3-mercapto-D-valine, cyclic (2-5)-disulfide …
Matched Description: … peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dezamizumab is under investigation in clinical trial NCT03417830 (Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging).
Investigational
Matched Synonyms: … recombinant monoclonal antibody to human serum amyloid P component ... ), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL GSK2398852 LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN G1, ANTI-(SERUM AMYLOID P PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL GSK2398852 HEAVY CHAIN …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 27) (human monoclonal SRF388 γ1-chain), disulfide with human
Displaying drugs 1251 - 1275 of 1607 in total