Displaying drugs 1276 - 1300 of 6835 in total
Retapamulin
Retapamulin, marketed by GlaxoSmithKline as the ointment Altabax, is an antibiotic for skin infections like impetigo. It was approved by the FDA in April 2007.
Approved
Matched Iupac: … (1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxotricyclo[5.4.3.0^{1,8}]tetradecan …
Isotretinoin
Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the...
Approved
Matched Iupac: … (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Products: … ISOFACE 5 MG ... Ciscutan 5 mg - Kapseln ... ORATANE CAPSULE 5 mg …
Matched Products: … ISOFACE 5 MG ... Ciscutan 5 mg - Kapseln ... ORATANE CAPSULE 5 mg …
Mifepristone
Mifepristone is a progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing syndrome....
Approved
Investigational
Human papillomavirus type 33 L1 capsid protein antigen
Human papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 33. The vaccine is prepared from the purified...
Approved
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Human papillomavirus type 6 L1 capsid protein antigen
Human papillomavirus type 6 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Human papillomavirus type 16 L1 capsid protein antigen
Human papillomavirus type 16 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Dezocine
Dezocine is a partial opiate drug and is used for pain management. Dezocine is a very effective alternative to fentanyl when administered during outpatient laparoscopy, although is associated with an increased incidence of postoperative nausea.
Approved
Investigational
Zileuton
Leukotrienes are substances that induce numerous biological effects including augmentation of neutrophil and eosinophil migration, neutrophil and monocyte aggregation, leukocyte adhesion, increased capillary permeability, and smooth muscle contraction. These effects contribute to inflammation, edema, mucus secretion, and bronchoconstriction in the airways of asthmatic patients. Zileuton relieves such symptoms through its...
Approved
Investigational
Withdrawn
Matched Description: … Both the R(+) and S(-) enantiomers are pharmacologically active as 5-lipoxygenase inhibitors in in vitro ... Zileuton relieves such symptoms through its selective inhibition of 5-lipoxygenase, the enzyme that catalyzes …
Ibritumomab tiuxetan
Indium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and...
Approved
Investigational
Populus alba pollen
Populus alba pollen is the pollen of the Populus alba plant. Populus alba pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 9 Tree Mix …
Sulfacetamide
An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Mixtures name: … Sulfacet-R ... Sulfacet R Lotion ... Se 10-5 Ss …
Sitagliptin
Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256]. The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255]....
Approved
Investigational
Matched Salts cas: … 654671-77-9 …
Matched Mixtures name: … SIPTATINMET R …
Matched Products: … İVOBRA 5 MG FİLM KAPLI TABLET, 56 ADET …
Matched Mixtures name: … SIPTATINMET R …
Matched Products: … İVOBRA 5 MG FİLM KAPLI TABLET, 56 ADET …
Fluvastatin
Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It...
Approved
Matched Description: … Fluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. …
Tofersen
Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational
Matched Synonyms: … RA-SP-T-SP-A-SP-M5C-SP-A-SP-T-SP-T-SP-T-SP-M5C-SP-T-SP-A-SP-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))R …
Carya ovata pollen
Carya ovata pollen is the pollen of the Carya ovata plant. Carya ovata pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 9 Tree Mix …
Platanus occidentalis pollen
Platanus occidentalis pollen is the pollen of the Platanus occidentalis plant. Platanus occidentalis pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 9 Tree Mix …
Rofecoxib
Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Products: … ARTROX 12..5 MG TABLETAS …
Poloxamer 188
Poloxamer 188 (P188) is a nonionic block linear copolymer that exhibits rheologic, anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models . Composed of two hydrophilic side-chains attached to a hydrophobic center core , its average molecular weight is 8400 Daltons. P188 was originally approved by the FDA in...
Approved
Investigational
Dexamethasone acetate
Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is structurally similar to other corticosteroids such as hydrocortisone and prednisolone. Dexamethasone acetate has largely been replaced by dexamethasone phosphate and...
Approved
Investigational
Vet approved
Matched Description: … In a June 16 2020 press release highlighting early results of a clinical trial, Randomized Evaluation …
Ibrexafungerp
Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection.[A235384,L34349] It was developed out of a need to treat fungal infections that may have become resistant to echinocandins or azole...
Approved
Investigational
Matched Synonyms: … 15R)-15-((2R)- 2-AMINO-2,3,3-TRIMETHYLBUTOXY)-1,6A,8,10A-TETRAMETHYL-8- ((2R)-3-METHYLBUTAN-2-YL)-14-(5- …
Matched Iupac: … ,21R)-21-[(2R)-2-amino-2,3,3-trimethylbutoxy]-5,7,10,15-tetramethyl-7-[(2R)-3-methylbutan-2-yl]-20-[5- …
Matched Iupac: … ,21R)-21-[(2R)-2-amino-2,3,3-trimethylbutoxy]-5,7,10,15-tetramethyl-7-[(2R)-3-methylbutan-2-yl]-20-[5- …
Mitomycin
Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of Streptomyces caespitosus.[L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. Few other antibiotics have been...
Approved
Matched Iupac: … 7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.0^{2,7}.0^{4,6}]trideca-1(9) …
Matched Description: … resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 …
Matched Products: … MUTAMYCIN ©INYECTABLE 5 MG. …
Matched Description: … resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 …
Matched Products: … MUTAMYCIN ©INYECTABLE 5 MG. …
Zinc phenolsulfonate
Approved
Experimental
Matched Mixtures name: … Racord Two No 9 ... Sil Trax Plus No 9 …
Fludrocortisone
Fludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to aldosterone, the body's primary endogenous mineralocorticoid, and is structurally analogous to cortisol, differing only by a fluorine atom at the 9-position of the steroid structure...
Approved
Investigational
Matched Description: … mineralocorticoid, and is structurally analogous to [cortisol], differing only by a fluorine atom at the 9- …
Fingolimod
Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. It was developed by Novartis and initially approved by the FDA in 2010. Fingolimod was also...
Approved
Investigational
Streptococcus pneumoniae type 9v capsular polysaccharide antigen
Streptococcus pneumoniae type 9v capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 9v of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Mixtures name: … Pneumococcal Polysaccharide Conjugate Vaccine (Adsorbed) (10-Valent) SUSPENSION FOR INJECTION (MULTIDOSE - 5 …
Displaying drugs 1276 - 1300 of 6835 in total