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Displaying drugs 1351 - 1375 of 1940 in total

Alprazolam

Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.[L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.[L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose to avoid withdrawal symptoms. Alprazolam's adverse...
Approved
Illicit
Investigational
Matched Synonyms: … 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Matched Description: … of the drug which may lead to coma and death. ... Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. ... ketoconazole and itraconazole. …
Matched Mixtures name: … Sentrazolam AM …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives ... Hydrocarbons, Cyclic ... Drugs that are Mainly Renally Excreted …
Matched Products: … Apo-alpraz ... Apo-alpraz Ts ... ABAXON AP 1MG …

Carba-nicotinamide-adenine-dinucleotide

Experimental
Matched Name: … Carba-nicotinamide-adenine-dinucleotide …
Matched Iupac: … )oxy](hydroxy)phosphoryl}oxy)methyl]-2,3-dihydroxycyclopentyl]-3-carbamoyl-1lambda5-pyridin-1-ylium ... 2S,3R,4R)-4-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl …

Stearic acid

Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. It is a waxy solid.
Approved
Experimental
Matched Description: … vegetable fats and oils. ... octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and ... It is a waxy solid. …
Matched Mixtures name: … Sha-lem …
Matched Products: … Dr.g A-clear Foam …

Hyaluronidase

Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. The action of hyaluronidase was first described in 1936, and named in 1939. Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective...
Approved
Matched Description: … Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered ... fluids, drugs, and contrast agents. ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Matched Products: … POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION PARA ADMINISTRACIÓN OFTALMICA …

House dust

House dust allergenic extract is used in allergenic testing.
Approved
Matched Products: … A. Dust ... AP House Dust Mix ... Center-AL - House Dust …

Vecuronium

Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other...
Approved
Investigational
Matched Iupac: … ,8S,9aS,9bS,11aS)-1,7-bis(acetyloxy)-9a,11a-dimethyl-8-(piperidin-1-yl)-hexadecahydro-1H-cyclopenta[a] …
Matched Description: … Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination ... as well as its short duration of action and easy reversibility provide advantages over, or alternatives ... A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. …
Matched Products: … BROCURIX 10 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... BROMURO DE VECURONIO 4 MG/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …

Aclerastide

Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic.
Investigational
Matched Synonyms: … ASP-ARG-NLE-TYR-ILE-HIS-PRO ... NorLeu3-A(1-7) ... NorLeu3-Angiotensin(1-7) [NorLeu3-A(1-7)] …
Matched Description: … Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Zolpidem

Zolpidem, also known as Ambien, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. It is aimed for use in patients with difficulties initiating sleep. This drug decreases the time to fall asleep (sleep latency), increases the...
Approved
Matched Synonyms: … N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamide …
Matched Iupac: … N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide …
Matched Description: … low risk of drug withdrawal, drug dependence, and drug tolerance [A175426]. ... It is available in both immediate acting and extended release forms [FDA label], [F3802]. ... This drug decreases the time to fall asleep (sleep latency), increases the duration of sleep, and decreases …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics ... GABA-A Receptor Agonists ... gamma-Aminobutyric Acid A Receptor Positive Modulator …
Matched Products: … ZOLPIDEM AL 5MG ... Apo-zolpidem ODT ... ZOLPIDEM AL 10MG …

Secnidazole

Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Description: … Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa ... to form a radical anion, thereby damaging and killing the target pathogen. ... improved oral absorption and a longer terminal elimination half-life than other drugs in this class. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... azithromycin, fluconazole and secnidazole …
Matched Products: … SECNICHEN POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL ... SECNIDAZOL PPS (POLVO PARA RECONSTITUIR A SUSPENSIÓN) ... SECNIPEN 750 MG POLVO PARA RECOSTRUIR A SUSPENSION ORAL …

Light green SF yellowish

Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in histological applications and other labratory settings, and usually exists as a disodium salt. The maximum absorption of light green SF...
Approved
Experimental
Matched Synonyms: … A F Green No.2 ... Acid Green A ... A.F. Green No. 2 …
Matched Description: … It is used in histological applications and other labratory settings, and usually exists as a disodium ... which are possibly due to low durability of the dye and increased tendency of the dye to fade. ... solution which is widely used as a counterstain. …

Azafenidin

Azafenidin is under investigation in clinical trial NCT01726582 (Pancreas Cancer: Molecular Profiling as a Guide to Therapy Before and After Surgery ("Personalized Medicine")).
Investigational
Matched Synonyms: … 2-(2,4-dichloro-5-(2-propynyloxy)phenyl)-5,6,7,8-tetrahydro-1,2,4-triazolo(4,3-a)pyridin-3(2h)-one ... 2-(2,4-dichloro-5-prop-2-ynyloxyphenyl)-5,6,7,8-tetrahydro-1,2,4-triazolo(4,3-a)pyridin-3(2h)-one …
Matched Description: … a Guide to Therapy Before and After Surgery ("Personalized Medicine")). ... Azafenidin is under investigation in clinical trial NCT01726582 (Pancreas Cancer: Molecular Profiling as …

Permethrin

A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Approved
Investigational
Matched Description: … A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. ... It is a yellow to light orange-brown, low melt-ing solid or viscous liquid. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides ... Scabicides, Insecticides and Repellents ... Hydrocarbons, Cyclic ... Drugs that are Mainly Renally Excreted …
Matched Products: … A Scabs ... A-LICES LOTION 1%w/w …

Linaclotide

Linaclotide is a synthetic 14-amino acid cyclic peptide and first-in-class guanylate cyclase-C (G-CC) agonist.[A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide hormones that are endogenous activators of GC-C. It is also a homolog of a heat-stable enterotoxin derived from Escherichia coli, the first natural ligand...
Approved
Matched Synonyms: … GLUTAMYL-L-TYROSYL-L-CYSTEINYL-L-CYSTEINYL-L-ASPARAGINYL-L-PROLYL-L-ALANYL-L-CYSTEINYL-L-THREONYLGLYCYL-L-CYSTEINYL-, CYCLIC …
Matched Description: … Linaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C ... [A260271] It gained EMA and Health Canada approval on November 26, 2012 [L47216] and December 3, 2013 ... [A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Gemcitabine

Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose. As a prodrug, gemcitabine is transformed...
Approved
Matched Description: … Gemcitabine is a nucleoside analog and a chemotherapeutic agent. ... [A233140] Gemcitabine is marketed as Gemzar and it is available as intravenous injection. ... [L32960] The structure, metabolism, and mechanism of action of gemcitabine are similar to [cytarabine …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides ... Drugs that are Mainly Renally Excreted ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … Aj-gemcitabine ... Act Gemcitabine ... PAMIGEN® 200MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIONINYECTABLE …

ABBV-CLS-7262

Investigational
Matched Synonyms: … ({(2S)-1,4-bis[2-(4-chloro-3- fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2- yl}oxy)methyl hydrogen phosphate …
Matched Iupac: … diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2-yl]oxy}methyl hydrogen phosphate …

Rehmannia glutinosa root

Rehmannia glutinosa root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Digitalis Glutinosa Root …
Matched Description: … It is not an approved drug. ... Rehmannia glutinosa root is a plant/plant extract used in some OTC (over-the-counter) products. …

Amino acids

Mixture of amino acids ; used for parenteral nutrition in infants.
Investigational
Matched Mixtures name: … Ari S-Liner …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Blood Substitutes and Perfusion Solutions …
Matched Products: … AMINOACIDI A CATENA RAMIFICATA ... AMINOACIDI A CATENA RAMIFICATA MONICO …

Clarithromycin

Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug...
Approved
Matched Synonyms: … 6-O-methylerythromycin A …
Matched Description: … translation and protein assembly process. ... Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the ... Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration …
Matched Mixtures name: … Lansoprazole, Amoxicillin, and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin …
Matched Categories: … Alimentary Tract and Metabolism ... Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins ... vonoprazan, amoxicillin and clarithromycin ... rabeprazole, amoxicillin and clarithromycin …
Matched Products: … Apo-clarithromycin ... Ava-clarithromycin ... Act Clarithromycin XL …

Iopamidol

Iopamidol is a contrast agent developed by Bracco with nonionic, low-osmolar properties.
Approved
Matched Description: … Iopamidol is a contrast agent developed by Bracco with nonionic, low-osmolar properties. …
Matched Categories: … Hydrocarbons, Cyclic ... Compounds used in a research, industrial, or household setting …
Matched Products: … IODICA …

Tetrabenazine

A drug formerly used as an antipsychotic but now used primarily in the symptomatic treatment of various hyperkinetic disorders. It is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease. FDA approved on August 15, 2008.
Approved
Investigational
Matched Synonyms: … 1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one ... 2-oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine …
Matched Iupac: … 9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-one …
Matched Description: … It is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease ... A drug formerly used as an antipsychotic but now used primarily in the symptomatic treatment of various …
Matched Categories: … Tetrabenazine and isomer …
Matched Products: … Apo-tetrabenazine …

Nitroglycerin

Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief...
Approved
Investigational
Matched Description: … Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent ... [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and ... [A249970] Nitroglycerin causes vasodilation in both arteries and veins. …
Matched Categories: … Nitrates and Nitrites ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Compounds used in a research, industrial, or household setting …
Matched Products: … TOP-NITRO ... Apo-nitroglycerin ... GITRINIL INJECTION 10ML AMP …

Telacebec

Investigational
Matched Synonyms: … 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperdinyl)phenyl)methyl)-imidazo(1,2-a)pyridine ... Imidazo(1,2-a)pyridine-3-carboxamide, 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperidinyl …
Matched Iupac: … 6-chloro-2-ethyl-N-[(4-{4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl}phenyl)methyl]imidazo[1,2-a]pyridine …

DSM-265

DSM265 has been used in trials studying the prevention and treatment of Malaria.
Investigational
Matched Synonyms: … 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin ... 2-(1,1-Difluoroethyl)-5-methyl-N-[4-(pentafluoro-λ6-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7 ... Sulfur, (4-((2-(1,1-difluoroethyl)-5-methyl(1,2,4)triazolo(1,5-a)pyrimidin-7-yl)amino)phenyl)pentafluoro …
Matched Iupac: … 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin …
Matched Description: … DSM265 has been used in trials studying the prevention and treatment of Malaria. …

KUR-113

KUR-113 is an investigational fibrin-based agent containing an N-terminally modified parathyroid hormone fragment. It is being investigated as a bioactive bone graft substitute.
Investigational
Matched Synonyms: … Fibrin-based agent containing a N-terminally modified parathyroid hormone fragment TGplPTH1-34 …
Matched Description: … It is being investigated as a bioactive bone graft substitute. ... KUR-113 is an investigational fibrin-based agent containing an N-terminally modified parathyroid hormone …

Alirocumab

Alirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of diet and statin treatment. It is a human monoclonal antibody part of the family of the PCSK9 inhibitors which...
Approved
Matched Description: … diet and statin treatment. ... FDA approval was contingent on the completion of further clinical trials to better determine efficacy and ... for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … PRALUENT SOLUTION FOR INJECTION IN A PRE-FILLED PEN 75MG/ML ... PRALUENT SOLUTION FOR INJECTION IN A PRE-FILLED PEN 150 MG/ML …
Displaying drugs 1351 - 1375 of 1940 in total