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Displaying drugs 1426 - 1450 of 1797 in total

Bortezomib D-mannitol

Approved
Matched Products: … Bortezomib for Injection ... Bortezomib for Injection Sdz …

Tedizolid

Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Investigational
Matched Description: … Pharmaceuticals as tedizolid phosphate (SIVEXTRO®). ... Tedizolid is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI ... This product is currently available as both an oral tablet and as a powder for intravenous injection. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … SIVEXTRO LYOPHILIZED POWDER FOR SOLUTION FOR INFUSION 200MG PER VIAL …

Terlipressin

Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor. It is a prodrug of lypressin, or lysine vasopressin. Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor. As a potent vasopressor, terlipressin has been...
Approved
Investigational
Matched Description: … Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for ... [L43217] As a potent vasopressor, terlipressin has been investigated in various shock states and conditions ... [A2601, A2602, A2603, A2604, A2605] It was also studied in hepatorenal syndrome (HRS) and variceal bleeding …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Insulins ... Vasopressin and Analogues …
Matched Products: … GLYPRESSIN FOR INJECTION 1 mg/vial ... GLYPRESSIN 1mg/8.5ml solution for injection ... GLYPRESSIN solution for injection, 1 mg/8.5 ml …

Agalsidase alfa

Agalsidase alfa is a recombinant human α-galactosidase A similar to agalsidase beta. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa,...
Approved
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Products: … REPLAGAL CONCENTRATE FOR SOLUTION FOR INFUSION 1 MG/ML …

2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid

Experimental
Matched Name: … 2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid …

Technetium Tc-99m medronate

Technetium (99mTc) medronic acid is a pharmaceutical product used in nuclear medicine imaging. It is composed of a technetium ion complexed with medronic acid, a type of bisphosphonate. Like other bisphosphonates used in the treatment of osteoporosis, medronic acid binds to the hydroxyapatite crystals within bone, and in this way...
Approved
Matched Iupac: … (⁹⁸Tc)technetium(4+) ion dihydrate (phosphonatomethyl)phosphonate …
Matched Description: … used in the treatment of osteoporosis, medronic acid binds to the hydroxyapatite crystals within bone, and ... in this way localizes the drug to bone for delineation of areas of altered osteogenesis. …
Matched Categories: … Indicators and Reagents …
Matched Products: … Kit for the Preparation of Technetium Tc 99M Medronate ... Kit for the Preparation of Technetium Tc 99m Medronate …

Tetrofosmin

Tetrofosmin was developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds. It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. Tetrofosmin is part of the group of diphosphines. Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.
Approved
Matched Products: … MYOVIEW POWDER FOR INJECTION ... MYOVIEW FOR INJECTION 0.23 mg/vial …

Antithymocyte immunoglobulin (rabbit)

Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of...
Approved
Matched Description: … Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Fluids and Secretions ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Thymoglobuline 5mg/ml Powder for concentrate for solution for infusion …

Inclisiran

Inclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 (PCSK9), which is a serine protease that regulates plasma low-density lipoprotein cholesterol (LDL-C) levels. By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and plasma...
Approved
Investigational
Matched Description: … inclisiran as the first and only approved siRNA for the treatment of adults with primary hypercholesterolemia ... RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and ... plasma LDL-C levels offers an additional benefit of reducing the risk of cardiovascular disease (CVD) and …
Matched Salts name: … Inclisiran sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Hypolipidemic Agents Indicated for Hyperlipidemia ... Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia …
Matched Products: … LEQVIO SOLUTION FOR INJECTION IN PREFILLED SYRINGE 284 MG/1.5 ML ... Sybrava 284mg/1.5ml Solution for Injection in Pre-filled Syringe …

Etanercept

Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Description: … [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region ... variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … ENBREL FOR INJECTION 25 mg/vial ... Enbrel Solution for Injection in a Pre-filled Pen 50mg ... Enbrel Solution for Injection in a Pre-filled Syringe 50mg …

Rituximab

Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Matched Description: … sequences and human constant region sequences [A40017], [FDA label]. ... chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and ... The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region …
Matched Categories: … Amino Acids, Peptides, and Proteins ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … Mabthera Concentrate for Solution for Infusion 100mg/10ml ... TRUXIMA® CONCENTRATE FOR SOLUTION FOR INFUSION 10MG/ML ... MABTHERA CONCENTRATE FOR SOLUTION FOR INFUSION 500 mg/50ml …

Ramucirumab

Ramucirumab is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability,...
Approved
Investigational
Matched Description: … VEGFR stimulation also mediates downstream signalling required for angiogenesis and is postulated to ... , and migration of human endothelial cells. ... By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … CYRAMZA CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/10ML ... CYRAMZA CONCENTRATE FOR SOLUTION FOR INFUSION 500MG/50ML ... Cyramza 100mg/10ml concentrate for solution for infusion …

Ustekinumab

Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses. It was generated via recombinant human IL-12 immunization of human Ig (hu-Ig) transgenic mice. It is a targeted biologic disease-modifying anti-rheumatic drug (bDMARDs) that...
Approved
Investigational
Matched Description: … was first approved for the treatment of adult patients with moderate to severe plaque psoriasis and ... [L9392] The dosing regimen for ustekinumab is based on the patient's weight and there are intravenous ... Ustekinumab is currently the first and only approved biologic therapy for ulcerative colitis that targets …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Biologics for psoriasis treatment ... Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents …
Matched Products: … STELARA CONCENTRATE FOR SOLUTION FOR INFUSION 130MG/26ML ... STELARA 130mg/26mL Concentrate for Solution for Infusion ... Solution for Injection 90mg/1ml …

Vinflunine

Vinflunine is a third-generation member of the vinca alkaloid family with anti-tumour actions. It was first described in 1998 at the Pierre Fabre research center in France. Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death...
Approved
Investigational
Matched Description: … , [DB00570], and [DB00541] [A31975]. ... vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and ... In murine tumors and human tumor xenografts, vinflunine exhibits an antitumor efficacy than [DB00361] …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Javlor Concentrate for Solution for Infusion 25 mg/mL …

Natalizumab

Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Description: … In 2006, the FDA reintroduced the drug to the market for multiple sclerosis. ... [A261326] Natalizumab was further approved by the FDA for the treatment of Crohn's Disease in January …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Tysabri Concentrate for Solution for Infusion 300mg/15ml …

Ropivacaine

Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Approved
Matched Description: … It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the …
Matched Salts name: … Ropivacaine hydrochloride anhydrous …
Matched Products: … ROPIVACAINE-AFT SOLUTION FOR INJECTION 1% W/V ... ROPIVACAINE-AFT SOLUTION FOR INFUSION 0.2% W/V ... ROPIVACAINE-AFT SOLUTION FOR INJECTION 0.2% W/V …

Blinatumomab

Blinatumomab is a BiTE-class (bi-specific T-cell engager) constructed monoclonal antibody formed by the recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through a short peptide linker.[A254836,L44311] CD3 is an antigen expressed on the surface of T-cells, while CD19 is mostly expressed on the surface of...
Approved
Investigational
Matched Description: … promotes tumor cell lysis and apoptosis. ... recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through ... acute lymphoblastic leukemia (ALL) in relapsed and refractory patients. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … BLINCYTO POWDER FOR INFUSION 35 MCG/VIAL ... BLINCYTO (Blinatumomab) for injection 35 mcg/vial …

9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid

Experimental
Matched Name: … 9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid …
Matched Iupac: … 9-hydroxy-8-methoxy-6-nitro-2H-phenanthro[3,4-d][1,3]dioxole-5-carboxylic acid …

3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)quinolin-2(1H)-one

Experimental
Matched Name: … 3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)quinolin-2(1H)-one …

Granisetron

A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Approved
Investigational
Matched Description: … A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant ... for cancer chemotherapy patients. …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … Granisetron Kabi concentrate for solution for infusion 1mg/ml ... KYTRIL FOR INFUSION 1MG/ML ... KYTRIL FOR INFUSION 3 mg/3ml …

Remdesivir

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia and acute respiratory distress syndrome (ARDS); COVID-19 can be fatal. Like other RNA viruses, SARS-CoV-2 depends on an RNA-dependent RNA polymerase...
Approved
Investigational
Matched Description: … the related SARS-CoV and MERS-CoV,[A222398] and has been investigated in multiple COVID-19 clinical ... disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia and ... , A222393] Broad antiviral activity of remdesivir is suggested by its mechanism of action,[A222398] and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Antivirals for Systemic Use …
Matched Products: … COVIFOR (REMDESIVIR FOR INJECTION 100MG/VIAL) ... VEKLURY® LYOPHILIZED POWDER FOR IV INFUSION 100MG/VIAL …

Thyrotropin alfa

Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of...
Approved
Vet approved
Matched Description: … linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites and ... similarity with the alpha subunit of human chorionic gonadotropin (hCG), luteinizing hormone (LH), and ... Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Thyrogen 0.9 mg Powder for Solution for Injection …

Idarucizumab

Idarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its anticoagulant effect. As a direct acting oral anticoagulant (DOAC), one of the risks associated with the use of dabigatran includes bleeding, espeically when...
Approved
Matched Description: … monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and ... Its use is associated with immediate, complete and sustained reversal of the anticoagulant effects of ... Approved under the tradename Praxbind (FDA), idarucizumab is indicated for the emergency treatment of …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … PRAXBIND Solution for Injection/Infusion 50 mg/ml ... PRAXBIND SOLUTION FOR INJECTION/INFUSION 50 MG/ML …

Nivolumab

Nivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation S228P for additional stability and reduced variability. It was developed by Bristol Myers Squibb. Nivolumab was...
Approved
Matched Description: … with the mutation _S228P_ for additional stability and reduced variability. ... [L12129] This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... nivolumab and relatlimab ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … OPDIVO CONCENTRATE FOR SOLUTION FOR INFUSION 10 MG/ML ... NIVOLUMAB BMS CONCENTRATE FOR SOLUTION FOR INFUSION 10MG/ML ... Opdivo 10mg/ml, Concentrate for solution for infusion …

Human immunoglobulin G

Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population....
Approved
Investigational
Matched Description: … Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human ... The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ... IgG subclasses are fully represented in the following proportions: 70.3% IgG1, 24.7% IgG2, 3.1% IgG3, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … GAMMAGARD S/D FOR INJECTION ... -C SOLUTION FOR INFUSION 10% ... OCTAGAM 5% SOLUTION FOR INFUSION …
Displaying drugs 1426 - 1450 of 1797 in total