Displaying drugs 126 - 150 of 13651 in total
Bexagliflozin
Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor.[A256408,A256413,L44758] Similar to other SGLT2 inhibitors, bexagliflozin contains three basic moieties: glucose, two benzene rings and a methylene bridge. SGLT2 is responsible for 60% to 90% of renal glucose re-uptake, and unlike other isoforms such as SGLT1, SGLT2 is...
Approved
Investigational
Matched Synonyms: … (2S,3R,4R,5S,6R)-2-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro ... D-glucitol, 1,5-anhydro-1-C-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-, (1s)- …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-(4-chloro-3-{[4-(2-cyclopropoxyethoxy)phenyl]methyl}phenyl)-6-(hydroxymethyl)oxane …
Matched Description: … Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor. ... other SGLT2 inhibitors, bexagliflozin contains three basic moieties: glucose, two benzene rings and a ... L44758] In January 2023, bexagliflozin was approved by the FDA for the treatment of adults with type 2 …
Matched Categories: … Diabetes Mellitus, Type 2, drug therapy ... Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-(4-chloro-3-{[4-(2-cyclopropoxyethoxy)phenyl]methyl}phenyl)-6-(hydroxymethyl)oxane …
Matched Description: … Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor. ... other SGLT2 inhibitors, bexagliflozin contains three basic moieties: glucose, two benzene rings and a ... L44758] In January 2023, bexagliflozin was approved by the FDA for the treatment of adults with type 2 …
Matched Categories: … Diabetes Mellitus, Type 2, drug therapy ... Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors …
Ciclopirox
Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. In particular, the agent is especially effective in treating Tinea versicolor.
Approved
Investigational
Matched Synonyms: … 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone …
Matched Iupac: … 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one …
Matched Description: … Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a …
Matched Salts cas: … 41621-49-2 …
Matched Mixtures name: … Ciclopirox 0.77% / Salicylic Acid 2% ... Ciclopirox Olamine 1% / Salicylic Acid 2% …
Matched Iupac: … 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one …
Matched Description: … Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a …
Matched Salts cas: … 41621-49-2 …
Matched Mixtures name: … Ciclopirox 0.77% / Salicylic Acid 2% ... Ciclopirox Olamine 1% / Salicylic Acid 2% …
Betaine
Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Synonyms: … 2-(Trimethylammonio)Acetate ... 2-trimethylammonioacetate ... 2-N,N,N-trimethylammonio acetate …
Matched Iupac: … 2-(trimethylazaniumyl)acetate …
Matched Description: … It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating ... Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. …
Matched Iupac: … 2-(trimethylazaniumyl)acetate …
Matched Description: … It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating ... Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. …
Raloxifene
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Synonyms: … (2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone …
Matched Iupac: … 2-(4-hydroxyphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]benzoyl}-1-benzothiophen-6-ol …
Matched Description: … Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic ... from [estradiol], raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a ... However, it has a negligible effect on altering the development and progression of breast cancer itself …
Matched Iupac: … 2-(4-hydroxyphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]benzoyl}-1-benzothiophen-6-ol …
Matched Description: … Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic ... from [estradiol], raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a ... However, it has a negligible effect on altering the development and progression of breast cancer itself …
Sertindole
Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. It is a phenylindole derivative used in the treatment of schizophrenia. It was first marketed in 1996 in several European countries before being withdrawn two years later because of...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one …
Matched Iupac: … 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one …
Matched Description: … It is a phenylindole derivative used in the treatment of schizophrenia. ... Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one …
Matched Description: … It is a phenylindole derivative used in the treatment of schizophrenia. ... Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
L-Lactic acid
Approved
Experimental
Matched Synonyms: … (S)-2-hydroxypropanoic acid ... (S)-2-hydroxypropionic acid …
Matched Iupac: … (2S)-2-hydroxypropanoic acid …
Matched Mixtures name: … Prismasol 2 …
Matched Iupac: … (2S)-2-hydroxypropanoic acid …
Matched Mixtures name: … Prismasol 2 …
Ceforanide
Ceforanide is administered parenterally. It has a longer elimination half-life than any currently available cephalosporin. Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms. Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to...
Approved
Matched Synonyms: … -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[[2-[2-(aminomethyl)phenyl]acetyl]amino]-3-[[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl] ... 7β-[2-(aminomethyl)phenyl]acetamido-3-{[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl-3,4-didehydrocepham …
Matched Iupac: … }methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-{2-[2-(aminomethyl)phenyl]acetamido}-3-({[1-(carboxymethyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl …
Matched Description: … It has a longer elimination half-life than any currently available cephalosporin. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … }methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-{2-[2-(aminomethyl)phenyl]acetamido}-3-({[1-(carboxymethyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl …
Matched Description: … It has a longer elimination half-life than any currently available cephalosporin. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Gemeprost
Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the cervix before surgical abortion. It is available as vaginal suppositories and also used in combination with the antiprogestin and mifepristone for termination of 1st- and 2nd-trimester pregnancy . It is not FDA-approved but available in...
Approved
Withdrawn
Matched Synonyms: … 16,16-Dimethyl-trans-delta-2-PGE1 methyl ester ... 16,16-Dimethyl-trans-delta(sup 2)-prostaglandin E1 methyl ester …
Matched Iupac: … hept-2-enoate ... methyl (2E)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4,4-dimethyloct-1-en-1-yl]-5-oxocyclopentyl] …
Matched Description: … Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the …
Matched Iupac: … hept-2-enoate ... methyl (2E)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4,4-dimethyloct-1-en-1-yl]-5-oxocyclopentyl] …
Matched Description: … Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the …
Darunavir
Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Synonyms: … N-((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-benzylpropyl)((1S,2R,5R)-4,6 ... -dioxabicyclo(3.3.0)oct-2-yloxy)carboxamide ... (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N1-isobutylsulfanilamido …
Matched Iupac: … ]-1-phenylbutan-2-yl]carbamate ... (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido …
Matched Description: … [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible ... Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] ... [L9227] As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard …
Matched Iupac: … ]-1-phenylbutan-2-yl]carbamate ... (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido …
Matched Description: … [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible ... Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] ... [L9227] As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard …
Moxonidine
Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Synonyms: … ]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid ... (2R,4R)-1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8- quinolinyl)sulfonyl …
Matched Iupac: … 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine …
Matched Description: … Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists …
Matched Iupac: … 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine …
Matched Description: … Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists …
Phentolamine
Phentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. While initially introduced to the market for the treatment of hypertension, this clinical use was halted due to cardiovascular and gastrointestinal adverse effects with the prolonged use of large oral doses of phentolamine.[A261781, A261786] It has several therapeutic uses, including...
Approved
Matched Synonyms: … 2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazoline ... 3-((4,5-DIHYDRO-1H-IMIDAZOL-2-YLMETHYL)(4-METHYLPHENYL)AMINO)PHENOL …
Matched Iupac: … 3-{[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino}phenol …
Matched Description: … Phentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. …
Matched Iupac: … 3-{[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino}phenol …
Matched Description: … Phentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. …
Linagliptin
Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes . Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding . Linagliptin was approved by...
Approved
Matched Synonyms: … (R)-8-(3-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methylquinazolin-2-ylmethyl)-3,7-dihydro-purine …
Matched Iupac: … 8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,3,6,7 …
Matched Description: … Linagliptin was approved by the FDA on May 2, 2011[L9557]. ... Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes ... Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,3,6,7 …
Matched Description: … Linagliptin was approved by the FDA on May 2, 2011[L9557]. ... Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes ... Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Clavulanic acid
Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Synonyms: … (Z)-(2R,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid …
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin …
Matched Mixtures name: … AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S ... AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S ... AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin …
Matched Mixtures name: … AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S ... AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S ... AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Sevoflurane
Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996....
Approved
Vet approved
Matched Synonyms: … 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane …
Matched Iupac: … 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane …
Matched Description: … [L42340] It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition ... Unlike other volatile anesthetics, sevoflurane has a pleasant odor and does not irritate the airway. ... [A249910] Therefore, it can be used for inhalational induction in adults and children for a wide variety …
Matched Iupac: … 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane …
Matched Description: … [L42340] It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition ... Unlike other volatile anesthetics, sevoflurane has a pleasant odor and does not irritate the airway. ... [A249910] Therefore, it can be used for inhalational induction in adults and children for a wide variety …
Tigecycline
Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005.
Approved
Matched Synonyms: … -3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide ... (4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro …
Matched Iupac: … -dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide ... (4S,4aS,5aR,12aS)-9-[2-(tert-butylamino)acetamido]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11 …
Matched Description: … Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil …
Matched Products: … TIGECLIN ® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE. ... TIGECICLINA 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... TIGEVITAE® 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Matched Iupac: … -dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide ... (4S,4aS,5aR,12aS)-9-[2-(tert-butylamino)acetamido]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11 …
Matched Description: … Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil …
Matched Products: … TIGECLIN ® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE. ... TIGECICLINA 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... TIGEVITAE® 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Indigotindisulfonic acid
Indigotindisulfonic acid is a blue-colored dye with a variety of uses.[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. This compound is an acid-base indicator and is used in the production of food colorants and pH tests. Indigotindisulfonic acid is used in...
Approved
Investigational
Matched Synonyms: … FD&C Blue #2 ... 2-(1,3-Dihydro-3-oxo-5-sulpho-2H-indol-2-ylidene)-3-oxoindoline-5-sulphonic acid …
Matched Description: … Indigotindisulfonic acid is a blue-colored dye with a variety of uses. ... Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Compounds used in a research, industrial, or household setting …
Matched Description: … Indigotindisulfonic acid is a blue-colored dye with a variety of uses. ... Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Compounds used in a research, industrial, or household setting …
Methionine
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Synonyms: … L-a-Amino-g-methylthiobutyric acid ... (S)-2-amino-4-(methylthio)butanoic acid ... (S)-2-amino-4-(methylthio)butyric acid …
Matched Iupac: … (2S)-2-amino-4-(methylsulfanyl)butanoic acid …
Matched Description: … It is a chelating agent for heavy metals. ... A sulfur containing essential amino acid that is important in many body functions. …
Matched Mixtures name: … AMINOMIX 2 NOVUM 1000 ML ... AMINOMIX 2 NOVUM 1500 ML ... AMINOMIX 2 NOVUM 2000 ML …
Matched Iupac: … (2S)-2-amino-4-(methylsulfanyl)butanoic acid …
Matched Description: … It is a chelating agent for heavy metals. ... A sulfur containing essential amino acid that is important in many body functions. …
Matched Mixtures name: … AMINOMIX 2 NOVUM 1000 ML ... AMINOMIX 2 NOVUM 1500 ML ... AMINOMIX 2 NOVUM 2000 ML …
Terbinafine
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Synonyms: … (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine ... (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine …
Matched Iupac: … [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine …
Matched Description: … Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. …
Matched Mixtures name: … Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Iupac: … [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine …
Matched Description: … Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. …
Matched Mixtures name: … Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Nifedipine
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Synonyms: … 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsäuredimethylester …
Matched Iupac: … 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar …
Matched Products: … ANHITEN-A …
Matched Iupac: … 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar …
Matched Products: … ANHITEN-A …
Bisacodyl
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700]
Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Synonyms: … Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester) …
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate …
Matched Description: … bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2- ... Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional ... A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a …
Matched Products: … Lax-A Go ... Feen-A-mint - Ect 5mg …
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate …
Matched Description: … bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2- ... Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional ... A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a …
Matched Products: … Lax-A Go ... Feen-A-mint - Ect 5mg …
Nomifensine
Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal...
Approved
Withdrawn
Matched Synonyms: … 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine ... 8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline …
Matched Iupac: … 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine …
Matched Description: … FDA published a notice of its determination that Merital capsules were removed from the market for safety …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine …
Matched Description: … FDA published a notice of its determination that Merital capsules were removed from the market for safety …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ergotamine
A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Approved
Matched Synonyms: … (5'α)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trione ... 12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione ... 12'-Hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergotaman-3',6',18-trione …
Matched Iupac: … (4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}] …
Matched Description: … A vasoconstrictor found in ergot of Central Europe. …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … (4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}] …
Matched Description: … A vasoconstrictor found in ergot of Central Europe. …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Methimazole
Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive options such as surgery or radioactive iodine therapy are inappropriate.[L8336,L8339]...
Approved
Matched Synonyms: … 1-Methylimidazole-2(3H)-thione …
Matched Iupac: … 1-methyl-2,3-dihydro-1H-imidazole-2-thione …
Matched Description: … Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones. ... [L8336,L8339] On a weight basis, methimazole is 10 times more potent than the other major antithyroid ... hepatotoxicity carried by the latter,[A184757] with propylthiouracil being preferred in pregnancy due to a …
Matched Iupac: … 1-methyl-2,3-dihydro-1H-imidazole-2-thione …
Matched Description: … Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones. ... [L8336,L8339] On a weight basis, methimazole is 10 times more potent than the other major antithyroid ... hepatotoxicity carried by the latter,[A184757] with propylthiouracil being preferred in pregnancy due to a …
N-acetyltyrosine
N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. DB00135 is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a...
Approved
Matched Synonyms: … Melanowhite-A ... (2s)-2-acetylamino-3-(4-hydroxyphenyl)propanoic acid ... (+)-(2s)-2-(acetylamino)-3-(4-hydroxyphenyl)propanoic acid …
Matched Iupac: … (2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid …
Matched Description: … [DB00135] is a non-essential amino acid with a polar side group. ... N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor ... It is typically administered as a source of nutritional support where oral nutrition is inadequate or …
Matched Iupac: … (2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid …
Matched Description: … [DB00135] is a non-essential amino acid with a polar side group. ... N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor ... It is typically administered as a source of nutritional support where oral nutrition is inadequate or …
Cinnamyl alcohol
Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon. Due to the low levels found in cinnamon, cinnamyl alcohol is usually supplied as DB14184 within commercial products.
Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% . Sensitivity...
Approved
Experimental
Matched Synonyms: … (2E)-3-phenylprop-2-en-1-ol …
Matched Iupac: … (2E)-3-phenylprop-2-en-1-ol …
Matched Description: … Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% [A34266 ... Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon. ... Sensitivity to cinnamyl alcohol may be identified with a clinical patch test. …
Matched Iupac: … (2E)-3-phenylprop-2-en-1-ol …
Matched Description: … Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% [A34266 ... Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon. ... Sensitivity to cinnamyl alcohol may be identified with a clinical patch test. …
Displaying drugs 126 - 150 of 13651 in total