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Displaying drugs 126 - 150 of 2871 in total
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Description: … the pupil,[L9413] and induce local vasoconstriction. ... Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate …
Matched Mixtures name: … Up and Up Nighttime Flu and Severe Cold and Cough ... Tylenol Sinus and Allergy Severe ... Up and Up Flu and Severe Cold and Cough Relief …
Matched Categories: … Monoamine Oxidase A Substrates ... Adrenergic and Dopaminergic Agents ... Mydriatics and Cycloplegics ... Decongestants and Antiallergics ... phenylephrine and ketorolac …
Matched Products: … CareOne Cold and Sinus ... Up and Up Sinus PE ... Up and Up nasal decongestant PE …
Chenopodium album pollen is the pollen of the Chenopodium album plant. Chenopodium album pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Lamb Quarters Chenopodium album ... Pollens - Weeds and Garden Plants, Lambs Quarters Chenopodium album …
Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Investigational
Matched Synonyms: … telomerase reverse transcriptase (hTERT) and IRES, respectively. ... -5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and ... A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human …
Approved
Experimental
Matched Mixtures name: … Tommie Copper Sport ... Tommie Copper Pain Relief Roller ... Tommie Copper Pain Relief Roller …
Matched Products: … Arthritis and Joint Pain Relief Thayers ... Weeks and Leo Medicated Vaporizing Steam ... Soothe and Move Pain Relief Cream …
Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows ... It is available as immediate- and extended-release formulations. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Fluids and Secretions ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection ... BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG …
Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhibitors.
Approved
Investigational
Matched Description: … It is used to control bleeding in hemophilia A and B patients with inhibitors. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … FEIBA (Factor VIII Inhibitor Bypassing Activity) 25U/ml Powder and solvent for solution for infusion ... FEIBA (Factor VIII Inhibitor Bypassing Activity) 50U/ml Powder and solvent for solution for infusion …
Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved
Matched Description: … It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. ... acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … FIBRYGA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... Fibryga 1g Powder and Solvent for Solution for Injection or Infusion …
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched Description: … This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of ... Esomeprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid ... DDAH inhibition causes a consequent accumulation of the nitric oxide synthase inhibitor asymmetric dimethylarginie …
Matched Mixtures name: … Naproxen and esomeprazole magnesium ... Naproxen and esomeprazole magnesium ... Naproxen and Esomeprazole Magnesium …
Matched Categories: … Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products …
Matched Products: … Foster and Thrive Acid Reducer ... Acid Reducer ... Harris Teeter Acid Reducer …
TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Investigational
Matched Synonyms: … Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), Rapamycin and
Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and deodorant agent. It works by physically blocking eccrine sweat gland ducts .
Approved
Matched Description: … Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and
Matched Mixtures name: … Lactovit DEODORANT AND ANTIPERSPIRANT INVISIBLE ANTISTAIN …
Matched Products: … Fraicheur Verveine Antiperspirant and Deodorant Roll-ON ... Fraicheur The Vert Antiperspirant and Deodorant Roll-ON ... Cyzone Blue and Blue for Him …
Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Synonyms: … 4-aminobenzoic acid ethyl ester …
Matched Description: … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and
Matched Mixtures name: … Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride …
Matched Categories: … Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid
Matched Products: … Alpha-Caine Topical Anesthetic ... Sting and Bite ... Bite and Sting relief …
Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell ... The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, …
Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Description: … [A18903,A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover …
Matched Mixtures name: … Clease and Treat ... Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit ... Erythromycin and Benzoyl Peroxide …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … AKNEFUG OXID WASH ... AKNEFUG-OXID MILD 3% ... AKNEFUG-OXID MILD 5% …
Approved
Experimental
Matched Products: … Dr.g Lock and More Nourishing Mask ... Dr.g Lock and More Sensi Calming Mask ... PLAY and JOY Cologne Maca Extra Hot Lubricant PJ-LBS201-35EU …
Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. It was first patented in 1957 and received its initial US approval in 1986.
Approved
Matched Synonyms: … Acide tranéxamique ... Tranexamic acid ... Tranexmic acid
Matched Name: … Tranexamic acid
Matched Iupac: … (1r,4r)-4-(aminomethyl)cyclohexane-1-carboxylic acid
Matched Description: … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and ... It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent ... [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … Tranexamic acid ... Tranexamic Acid ... TRANEXAMIC ACID
AB-201 is a CAR-NK cell therapy targeted against HER2. It is under investigation for the treatment of HER2-positive cancers, including breast and gastric carcinomas.
Investigational
Matched Synonyms: … allogeneic cord blood-derived NK cells that have been genetically modified to express a HER2-directed CAR and
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …
OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …
Approved
Investigational
Matched Synonyms: … Acetic acid, zinc salt ... Zinc acetato ... Zinc(II) acetate
Matched Name: … Zinc acetate
Matched Iupac: … zinc(2+) diacetate …
Matched Mixtures name: … Diphenhydramine HCI and Zinc Acetate ... Diphenhydramine HCl and Zinc Acetate ... Diphenhydramine HCl and Zinc Acetate
Matched Salts name: … Zinc acetate dihydrate …
Matched Categories: … zinc acetate ... Acids, Acyclic ... Carboxylic Acids ... Acetates ... Alimentary Tract and Metabolism …
Matched Products: … Halls Zinc Defense …
Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and tablet-based products are available.[L14021, L14024, L14027,...
Approved
Investigational
Vet approved
Matched Description: … [A203636] It is widely used to treat mucosal yeast infections, including both oral and vaginal infections ... although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and ... [A203636, A203639] Miconazole was first synthesized in 1969 and first granted FDA approval on January …
Matched Mixtures name: … Up and Up Miconazole 1 ... Up and Up Miconazole 1 ... Up and Up Miconazole 1 …
Matched Categories: … 14-alpha Demethylase Inhibitors ... Antiinfectives and Antiseptics for Local Oral Treatment ... Imidazole and Triazole Derivatives ... Vaginal Creams, Foams, and Jellies ... Genito Urinary System and Sex Hormones …
Matched Products: … MICONAZOL ACIS CREME ... Up and Up Miconazole 7 ... Soothe And Cool Treat …
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Description: … drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and
Matched Mixtures name: … Up and Up Cold and Sinus ... Up and Up allergy and congestion relief ... Up and Up Sinus and Cold D …
Matched Categories: … Alpha-and Beta-adrenergic Agonists ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Up and Up Suphedrine ... UP AND UP nasal decongestant ... Up and Up 12 Hour Nasal Decongestant …
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY, BISPECIFIC ... -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND
Matched Description: … arm comprising a heavy and light chain. ... It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each ... Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Description: … During exercise, the plasma allantoin concentration rapidly increases about two fold and remains elevated ... More specifically, allantoin is a diureide of glyoxylic acid that is produced from uric acid. ... Allantoin is a substance that is endogenous to the human body and also found as a normal component of …
Matched Mixtures name: … Essential Solution Hyaluronic Acid Mask Sheet ... Aspiera Wound Care and Antiseptic ... Aspiera Wound Care and Antiseptic …
Matched Categories: … Basic Ointments and Protectants ... Herbs and Natural Products …
Matched Products: … Atobos Centella and Wash ... Healing Foot and Leg Balm ... Original Power Whitening and Lineless Ampoule …
Investigational
Matched Synonyms: … engager antibody with a single chain fc moiety that binds to b cell maturation antigen surface receptor and
Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Description: … Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules ... [A190978] The most common preparations of PEGs include PEG 3350 and PEG 400. ... [A190975] Molecular weights of PEGs vary by time of the polymerization process and the molecular weight …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... PEG-3350 and Electrolytes ... HalfLytely and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up Powderlax ... Polyethylene Glycol 3350 and Electrolytes ... Berkley and Jensen Clearlax …
Displaying drugs 126 - 150 of 2871 in total