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Displaying drugs 126 - 150 of 8055 in total
CD22 is a lineage-restricted B-cell antigen that is expressed solely in on B-chronic lymphocytic leukemia, hairy cell leukemia, acute lymphocytic leukemiathe and Burkitt's lymphoma. The predecessor of Moxetumab pasudotox (MxP), named BL22, was first created based on the antibody RFB4 which specifically binds to CD22. This antibody was used to...
Approved
Investigational
Matched Description: … [A38864] MxP appears as an improved form of BL22 by the mutation of the Fv region and the antibody ... The predecessor of Moxetumab pasudotox (MxP), named BL22, was first created based on the antibody RFB4 ... was developed by Astra Zeneca and FDA approved on September 13, 2018, after being granted the status of
Matched Categories: … CD22 (Clusters of Differentiation 22) inhibitors …
Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.[A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than nonionic iodinated contrast agents. Approved by the FDA...
Approved
Investigational
Matched Description: … agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of ... [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than …
Matched Categories: … Diagnostic Uses of Chemicals …
A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
Approved
Matched Description: … A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic …
Matched Categories: … Diagnostic Uses of Chemicals …
Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …
Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Approved
Withdrawn
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Bazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. It is approved in the...
Approved
Investigational
Matched Description: … their takeover of Wyeth Pharmaceuticals. ... prevention (not treatment) of postmenopausal osteoporosis. ... generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of
Matched Categories: … Sex Hormones and Modulators of the Genital System …
A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Approved
Matched Description: … A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma. …
Matched Categories: … combinations of sulfonamides …
Iopamidol is a contrast agent developed by Bracco with nonionic, low-osmolar properties.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …
A narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …
Mangafodipir is a contrast agent used as a diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver and pancreas. This drug is made up of paramagnetic manganese (II) ions combined with the chelating agent fodipir (dipyridoxyl diphosphate, DPDP). Manganese absorption into the tissues that...
Approved
Investigational
Withdrawn
Matched Description: … Enhanced contrast by mangafodipir improves visualization and detection of lesions of the liver formed ... diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of ... This drug is made up of paramagnetic manganese (II) ions combined with the chelating agent _fodipir_ …
Matched Categories: … Diagnostic Uses of Chemicals …
An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Approved
Matched Description: … The sodium salt of the drug is better tolerated than the free acid. …
Matched Categories: … Drugs for Treatment of Tuberculosis …
Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Approved
Vet approved
Matched Description: … Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum …
Matched Categories: … combinations of penicillins …
Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues. Iodine has a high atomic density, which gives it the ability to attenuate X-rays. The intravascular administration of iodine compounds, such as ioversol, enhances...
Approved
Matched Description: … of internal structures. ... between vessels in the path of the flow of the contrast medium and normal tissue, allowing the visualization ... tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of
Matched Categories: … Diagnostic Uses of Chemicals …
Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is considered...
Approved
Investigational
Matched Description: … the potency of [morphine]. ... a lower-risk opioid option for the treatment of moderate to severe pain. ... Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms …
Matched Mixtures name: … Harvest Of Values All B Complex Tab ... Herbs of Gold B Complex Plus Softgel …
Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. More specifically, folic acid is required by the body for the synthesis of purines, pyrimidines, and methionine before incorporation into DNA...
Approved
Nutraceutical
Vet approved
Matched Description: … This results in a deficiency of coenzymes and a resultant buildup of toxic substances that are responsible ... , and erythropoiesis, and plays a protective factor in the development of cancer. ... Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential …
Matched Mixtures name: … Harvest Of Values All B Complex Tab ... Herbs of Gold B Complex Plus Softgel …
A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
Approved
Investigational
Withdrawn
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Lisdexamfetamine is a prodrug of dextroamphetamine, a central nervous system stimulant known as d-amphetamine, covalently attached to the naturally occurring amino acid L-lysine. Lisdexamfetamine is the first chemically formulated prodrug stimulant and was first approved by the FDA in April 2008. It was also approved by Health Canada in February...
Approved
Investigational
Matched Description: … Lisdexamfetamine is a prodrug of [dextroamphetamine], a central nervous system stimulant known as d-amphetamine …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Approved
Illicit
Matched Description: … Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with …
Matched Categories: … combinations of barbiturates …
Nomegestrol is an ingredient in the EMA-authorised product Zoely.
Approved
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Pentetreotide has been used in trials studying the diagnosis of Cushing's syndrome.
Approved
Investigational
Matched Description: … Pentetreotide has been used in trials studying the diagnosis of Cushing's syndrome. …
Matched Categories: … Diagnostic Uses of Chemicals …
Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Description: … Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of ... It functions by preventing resorption of bone[FDA Label][A959]. …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
Approved
Matched Description: … [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. ... Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram ... actively dampens the activity of escitalopram rather than existing simply as an inactive enantiomer. …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Approved
Investigational
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Displaying drugs 126 - 150 of 8055 in total