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Displaying drugs 1476 - 1500 of 2943 in total
Platelet lysate is an acellular compound composed of platelet proteins while also being void of cellular debris, thus making the lysate rich with growth factors. It is extracted through lysis of the plasma membrane of platelets. Because white cell antigens are low in prepared lysate, there is a minimized likelihood...
Investigational
Matched Name: … Platelet Lysate
Matched Description: … debris, thus making the lysate rich with growth factors. ... [A220188] It is extracted through lysis of the plasma membrane of platelets. ... Platelet lysate is an acellular compound composed of platelet proteins while also being void of cellular …
Experimental
Matched Synonyms: … bromo-N-hydroxyanilino)-hydroxymethyl]sulfanyl-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid ... L-γ-Glutamyl-S-[(S)-[(4-bromophenyl)(hydroxy)amino](hydroxy)methyl]-L-cysteinylglycine …
Matched Iupac: … bromophenyl)(hydroxy)amino](hydroxy)methyl]sulfanyl}-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins …
A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Approved
Illicit
Matched Synonyms: … 5-ethyl-5-isoamylbarbituric acid ... 5-ethyl-5-isopentylbarbituric acid ... 5-ethyl-5-(3-methylbutyl)barbituric acid
Matched Description: … A barbiturate with hypnotic and sedative properties (but not antianxiety). ... Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with …
Matched Categories: … Hypnotics and Sedatives …
Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide...
Approved
Matched Synonyms: … Glucagon-like peptide II (2-glycine) (human) …
Matched Description: … Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). ... It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Various Alimentary Tract and Metabolism Products …
Approved
Experimental
Matched Synonyms: … 4-hydroxybenzoic acid ethyl ester ... p-hydroxybenzoic acid ethyl ester …
Matched Categories: … Increased Histamine Release ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic.
Investigational
Matched Synonyms: … 1-7-ANGIOTENSIN II, 3-L-NORLEUCINE-5-L-ISOLEUCINE
Matched Iupac: … hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carboxylic acid
Matched Description: … Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in the United Kingdom, United States and Canada as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, and...
Approved
Investigational
Nutraceutical
Matched Synonyms: … 5-hydroxy-L-tryptophan
Matched Iupac: … (2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
Matched Description: … 5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and ... suppressant, and sleep aid, and is also marketed in many European countries for the indication of major ... metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
A cephalorsporin antibiotic that is no longer commonly used.
Approved
Matched Synonyms: … Cephaoglycin acid ... 7-(2-D-alpha-Aminophenylacetamido)cephalosporanic acid ... 7-(D-alpha-Aminophenyl-acetamido)cephalosporanic acid
Matched Iupac: … acetyloxy)methyl]-7-[(2R)-2-amino-2-phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Experimental
Matched Synonyms: … 3-deoxy-α-D-manno-oct-2-ulopyranosonic acid ... α-2-keto-3-deoxyoctulosonic acid pyranose …
Matched Name: … 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid
Matched Iupac: … (2R,4R,5R,6R)-6-[(1R)-1,2-dihydroxyethyl]-2,4,5-trihydroxyoxane-2-carboxylic acid
Experimental
Matched Synonyms: … (Z)-2-aminobutenoic acid ... (2Z)-2-aminobut-2-enoic acid
Matched Name: … alpha,beta-Dehydroaminobutyric acid
Matched Iupac: … (2Z)-2-aminobut-2-enoic acid
Hydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928. It was first approved by the FDA in 1998 for the treatment of sickle cell anemia in adults. Although clinical evidence on the efficacy of hydroxyurea in certain conditions exists, hydroxyurea...
Approved
Matched Synonyms: … Carbamohydroxamic acid ... Carbamohydroximic acid
Matched Description: … adherence, the need for therapeutic monitoring, and serious side effects of secondary cancer and birth ... conditions exists, hydroxyurea is used sparingly in clinical settings, largely due to lack of knowledge and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Cefalotin is a cephalosporin antibiotic.
Approved
Investigational
Vet approved
Matched Synonyms: … 7-(2-Thienylacetamido)cephalosporanic acid ... 7-(2'-thienylacetamido)cephalosporanic acid ... 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid
Matched Iupac: … acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Experimental
Matched Synonyms: … 3-Indoxylsulfuric acid ... Indoxyl sulfic acid ... Indoxylsulfuric acid
Matched Iupac: … (1H-indol-3-yl)oxidanesulfonic acid
JAK4D is a first-in-class thyrotropin-releasing hormone (TRH)-based compound.
Investigational
Matched Synonyms: … L-pyroglutamyl-l-asparaginyl-l-prolyl-d-tyrosyl-d-tryptophan amide …
Experimental
Matched Synonyms: … 2-Hydroxy-5-{[(2E)-1-(2-naphthyloxy)-4-oxo-2-buten-2-yl]amino}-L-tyrosine
Matched Name: … 2-Hydroxy-5-({1-[(2-Naphthyloxy)Methyl]-3-Oxoprop-1-Enyl}Amino)Tyrosine
Matched Iupac: … -2-amino-3-(2,4-dihydroxy-5-{[(2E)-1-(naphthalen-2-yloxy)-4-oxobut-2-en-2-yl]amino}phenyl)propanoic acid
Experimental
Matched Name: … L-[(N-Hydroxyamino)Carbonyl]Phenylalanine
Matched Iupac: … (2S)-2-[(hydroxycarbamoyl)amino]-3-phenylpropanoic acid
Experimental
Matched Name: … D-[(N-Hydroxyamino)Carbonyl]Phenylalanine
Matched Iupac: … (2R)-2-[N-hydroxy-(C-hydroxycarbonimidoyl)amino]-3-phenylpropanoic acid
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid ... 2-amino-3-(4-bromobenzoyl)benzeneacetic acid
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Experimental
Matched Synonyms: … L-γ-Glutamyl-S-octyl-D-cysteinylglycine …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-(octylsulfanyl)ethyl]carbamoyl}butanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins …
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Synonyms: … Isonicotinic acid hydrazide ... Pyridine-4-carboxylic acid hydrazide …
Matched Categories: … Acids, Heterocyclic ... Isonicotinic Acids ... Fatty Acid Synthesis Inhibitors ... ethambutol and isoniazid ... rifampicin and isoniazid …
Felbamate is an anticonvulsant drug used in the treatment of epilepsy. In particular, in the adult patient population, it can be employed to treat partial seizures (with and without generalization). Alternatively, it is used to treat partial and generalized seizures associated with Lennox-Gastaut syndrome in children. It has a weak...
Approved
Matched Synonyms: … carbamic acid 2-phenyltrimethylene ester ... Carbamic acid 3-carbamoyloxy-2-phenyl-propyl ester …
Matched Description: … In particular, in the adult patient population, it can be employed to treat partial seizures (with and ... Alternatively, it is used to treat partial and generalized seizures associated with Lennox-Gastaut syndrome …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists …
Experimental
Matched Synonyms: … β-glycerophosphoric acid ... beta-Glycerophosphoric acid
Matched Iupac: … [(1,3-dihydroxypropan-2-yl)oxy]phosphonic acid
Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb. Its sale was discontinued in 2003 in some countries, due to the small possibility of hepatic (liver) injury. Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or even death, with...
Approved
Withdrawn
Matched Description: … Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb ... On May 20, 2004, Bristol-Myers Squibb discontinued the sale of Serzone in the United States. …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … Serzone ... Serzone-5ht2 …
Experimental
Matched Name: … N-BENZOYL-D-ALANINE
Matched Iupac: … (2R)-2-(phenylformamido)propanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Experimental
Matched Name: … [[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTER …
Displaying drugs 1476 - 1500 of 2943 in total