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Displaying drugs 1551 - 1575 of 1789 in total
Polymyxin B was discovered in the 1940s . They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes . Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. All gram-positive bacteria, fungi, and the gram-negative cocci,...
Approved
Vet approved
Matched Description: … Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic ... It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused ... Polymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line …
Matched Mixtures name: … DEXAMETASONA SODIO FOSFATO+ POLIMIXINA B SULFATO + NEOMICINA SULFATOSOLUCION OFTALMICA ... NEOMICINA SULFATO 3.5 MG + DEXAMATASONA SODIO FOSFATO 1.3MG + POLIMIXINA B SULFATO 6.600U.I / ML SOLUCION ... DEXAMETASONA SODIO FOSFATO 1.3 MG/ML. SOLUCIÓN OFTÁLMICA ESTÉRIL. …
Matched Salts name: … Polymyxin B sulfate
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Ophthalmological and Otological Preparations ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Polymyxin B for Injection USP ... POLY-MxB for Injection U.S.P. 500,000 Units (Lyophilized) …
A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched Iupac: … (10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin
Matched Description: … Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... Etoposide acts primarily in the G2 and S phases of the cell cycle. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. …
Matched Salts name: … Etoposide phosphate
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … MYLAN ETOPOSIDE CONCENTRATE FOR SOLUTION FOR INJECTION 20MG/ML ... ETOPOSIDE CONCENTRATE FOR SOLUTION FOR INJECTION 20mg/ml ... SEDOL - Etoposide Concentrate for Solution for Infusion 20 mg/ml …
Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, rilpivirine.[A227668,L31188,L31193] Early research into cabotegravir showed it had lower oral bioavailability than dolutegravir, which resulted in the development of long acting monthly intramuscular injection formulation for cabotegravir.[A227668,L31193] Cabotegravir was granted FDA approval on...
Approved
Investigational
Matched Description: … dosing every two months on February 01, 2022 [L40084] and without the need for an oral lead-in period ... A227668] which resulted in the development of long acting monthly intramuscular injection formulation for ... While previously administered once monthly only, this combination product was granted FDA approval for
Matched Salts name: … Cabotegravir sodium
Matched Categories: … Antivirals for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Apretude 600mg Prolonged-release suspension for injection …
Approved
Matched Products: … Pandemic Influenza Vaccine H5N1 Baxter Suspension for Injection …
Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Description: … pain relief and adjunctive to an anaesthetic. ... causes respiratory depression and analgesia. ... a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and
Matched Categories: … Hypnotics and Sedatives ... Fentanyl and fentanyl analogues …
Matched Products: … Remifentanil Reig Jofre 5mg Powder for Concentrate for Solution for Injection or Infusion ... Remifentanil for Injection ... ULTIVA FOR INJECTION 1 mg/vial …
Gadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine, and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions with abnormal vascularity or those thought to disrupt the normal blood-brain barrier.[A263076,A263081,L49871] It was 1 of the 3 macrocyclic gadolinium-based contrast agents (GBCAs)...
Approved
Investigational
Matched Description: … Gadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine, and ... A263076] Initially approved by the FDA in 1992, gadoteridol received additional approval in 2020 for
Matched Products: … ProHance 279.3 mg/ml solution for injection …
Imidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.
Investigational
Matched Description: … Imidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant. …
Matched Products: … PRILIUM 150MG POWDER FOR ORAL SOLUTION …
An antisense oligonucleotide that induces survival motor neuron (SMN) protein expression, it was approved by the U.S. FDA in December, 2016 as Spinraza for the treatment of children and adults with spinal muscular atrophy (SMA). It is adminstrated as direct intrathecal injection.
Approved
Investigational
Matched Description: … FDA in December, 2016 as Spinraza for the treatment of children and adults with spinal muscular atrophy …
Matched Salts name: … Nusinersen sodium
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Spinraza 12 mg Solution for Injection …
Brolucizumab, also known as RTH258 or ESBA1008, is a monoclonal antibody indicated to treat neovascular age related macular degeneration. Brolucizumab was granted FDA approval in October 2019.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Pagenax 120mg/ml Solution For Injection …
Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for use in...
Approved
Matched Description: … Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for ... biological activity of endogenous LH; an acute rise of LH, or LH surge, in females triggers ovulation and
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
Matched Products: … LUVERIS FOR INJECTION 75 iu/vial (Revised formula) …
Verteporfin, marketed as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers: CL-315555 and CL-315585. It is used as a photosensitizer in photodynamic therapy to eliminate abnormal blood vessels in wet form macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red...
Approved
Investigational
Matched Description: … as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers: [CL-315555] and ... Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light ... wavelength of 693 nm in the presence of oxygen, produces highly reactive short-lived singlet oxygen and
Matched Products: … VISUDYNE FOR INJECTION 15 mg/vial …
Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.
Approved
Investigational
Matched Description: … It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Oxytocin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Insulins …
Matched Products: … DURATOCIN RTS SOLUTION FOR INJECTION 100 MCG/ML ... Pharmidea Carbetocin 100 microgram/ml solution for injection …
Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen species [FDA Label]
Approved
Investigational
Vet approved
Matched Description: … of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and
Matched Mixtures name: … Multivitamins and Minerals for Men ... Multivitamins and Minerals for Women ... Luna Vitamin and Mineral Bar for Women …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … selenase 500 micrograms, solution for injection (50 micrograms/ml) ... selenase ® 100 micrograms, solution for injection (50 micrograms/ml) …
Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Description: … tissues in adult and pediatric patients (2 years of age and older) to detect and visualize areas with ... its chelating properties, and gadolinium (Gd3+). ... disruption of the blood-brain barrier (BBB) and/or abnormal vascularity. …
Matched Products: … DOTAGRAF SOLUTION FOR INJECTION 0.5 MMOL/ML ... CLARISCAN SOLUTION FOR INJECTION IN VIAL 0.5 MMOL/ML ... CLARISCAN SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 0.5 MMOL/ML …
Lipegfilgrastim, previously known as XM22, is a pegylated, recombinant granulocyte colony-stimulating factor (G-CSF) that was synthetized using a highly site-specific glycoPEGylation technology . It is used as an alternate to DB00019 for prophylactic use in cancer patients receiving chemotherapy and at risk for developing chemotherapy-induced neutropenia. Since July 2013, lipegfilgrastim...
Approved
Investigational
Matched Description: … Da for glycylsialic acid and approximately 20,000 Da for PEG [L2449]. ... and at risk for developing chemotherapy-induced neutropenia. ... Severe chemotherapy-induced neutropenia and febrile neutropenia significantly increases the risk for
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … LONQUEX SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 6MG/0.6ML …
Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. It is an active immunization against rabies that can be administered pre- or post-exposure to the rabies virus.
Approved
Investigational
Matched Description: … Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. …
Matched Categories: … Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use …
Matched Products: … Rabipur Lyophilised Powder for Injection …
Sage oil is extracted from sage or Salvia officinalis, the herb commonly used for culinary purposes. Salvia officinalis is a common sage and a member of the genus Salvia, that includes aromatic and perennial plants with flowers. Essential oil has been traditionally used in medicine for the relief of pain...
Nutraceutical
Matched Description: … Essential oil has been traditionally used in medicine for the relief of pain and the treatment of inflammation ... Sage oil is extracted from sage or *Salvia officinalis*, the herb commonly used for culinary purposes ... *Salvia officinalis* is a common sage and a member of the genus *Salvia*, that includes aromatic and
Matched Products: … Storks Synergy for balance of uterus …
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Description: … Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... It has a significant impact on both the physical and social functioning of affected individuals. ... [A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated …
Matched Products: … Betahist Forte Tablets 16mg ... VASOSERC FORT 16 MG TABLET, 60 ADET ... ROTASTIN FORT 16 MG TABLET, 60 ADET …
Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so...
Approved
Matched Description: … It is also used to treat lice infestation of the head and body. ... Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. ... It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides, Insecticides and Repellents …
Matched Products: … SCABİN %25 FORT LİKİT …
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Approved
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … BETAFERON FOR INJECTION 0.25 mg/ml …
Experimental
Matched Name: … (2r)-2-{[Formyl(Hydroxy)Amino]Methyl}Hexanoic Acid …
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment ... [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal ... Levomefolate Calcium Acetylcysteine Mecobalamin Algal …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Antidote for Acetaminophen Overdose …
Matched Products: … SIRAN FORTE ... ANCARE SOLUTION FOR IV INFUSION 100MG/ML ... HIDONAC SOLUTION FOR INFUSION 5 g/25 ml …
Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor (G-CSF) analog produced by recombinant DNA technology. It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in E. Coli. Human...
Approved
Matched Description: … [L40719] It has a number of therapeutic uses, including the management and prevention of infections and ... cell collection and therapy. ... acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Nivestim 120mcg/0.2mL Solution for Injection/Infusion ... Nivestim 480mcg/0.5mL Solution for Injection/ Infusion ... Nivestim 300mcg/0.5mL Solution for Injection/Infusion …
An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and...
Approved
Withdrawn
Matched Description: … [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the ... prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. …
Matched Categories: … Detoxifying Agents for Antineoplastic Treatment …
Matched Products: … Dexrazoxane for Injection …
Oil extracted from olives . Consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic. Used as a source of fatty acids in total parenteral nutrition and as an additive in some cosmetic products [FDA Label].
Approved
Matched Description: … Consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic. ... Used as a source of fatty acids in total parenteral nutrition and as an additive in some cosmetic products …
Matched Mixtures name: … OLIMEL N7E, emulsion for infusion ... OLIMEL N9E, emulsion for infusion ... PERIOLIMEL N4E, emulsion for infusion …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Intensive Treatment Bodyoil for Mommy To Be All Skin …
Displaying drugs 1551 - 1575 of 1789 in total