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Displaying drugs 1576 - 1600 of 1858 in total

Galsulfase

Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate...
Approved
Investigational
Matched Description: … enzyme activity and is conserved in all members of the sulfatase enzyme family. ... The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation ... sites, four of which carry a bis mannose-6-phosphate manose7 oligosaccharide for specific cellular recognition …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Chondroitinases and Chondroitin Lyases …
Matched Products: … Naglazyme Concentrated Solution for Intravenous Infusion 1mg/1ml …

Technetium Tc-99m albumin colloid

Approved
Experimental
Matched Products: … Pulmolite, Kit for the Preparation of Technetium Tc99m Albumin Aggregated …

Dupilumab

Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and ... immunological reactions in several atopic or allergic conditions, such as eczema, allergic reaction, and ... dermatitis, asthma as an add-on maintenance treatment, chronic rhinosinusitis with nasal polyposis, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Agents for Dermatitis, Excluding Corticosteroids …
Matched Products: … Dupixent 300 mg Solution for Injection in Pre-filled Syringe ... Dupixent 200mg Solution for Injection in Pre-Filled Syringe ... DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml …

Carvedilol

Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.[L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.[L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as...
Approved
Investigational
Matched Description: … , and the R(+) enantiomer is an alpha-1 adrenoceptor blocker. ... Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker ... [L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension …
Matched Salts name: … Carvedilol phosphate …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Alpha and Beta Blocking Agents ... carvedilol and ivabradine ... Antihypertensive Agents Indicated for Hypertension ... Calcium Channel Blockers …
Matched Products: … Carvedilol Phosphate …

Edaravone

Edaravone is a free radical scavenger and neuroprotective agent with antioxidant properties. It has three tautomers. Edaravone works to scavenge reactive oxygen species, which have been implicated in neurological disorders, such as amyotrophic lateral sclerosis (ALS) and cerebral ischemia.[A19140,L44007,A254257] The intravenous formulation of edaravone was first approved in Japan in...
Approved
Investigational
Matched Description: … Medicinal Products for Human Use (CHMP) for a long-term study demonstrating the long-term efficacy and ... [L44007] It was later approved for the treatment of amyotrophic lateral sclerosis (ALS) in Japan and ... Edaravone is a free radical scavenger and neuroprotective agent with antioxidant properties. …
Matched Products: … RADICAVA™ IV Concentrate Solution for Infusion 30mg/20mL …

Arsenic trioxide

Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous...
Approved
Investigational
Matched Description: … The enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Arsenic Trioxide for Injection ... Teva-arsenic Trioxide for Injection ... Arsenic Trioxide Solution for Injection …

Clostridium botulinum

Experimental
Matched Products: … DYSPORT FOR INJECTION 300u/vial ... DYSPORT FOR INJECTION 500 u/vial ... NEURONOX LYOPHILIZED POWDER FOR INJECTION 100 UNITS/VIAL …

Hepatitis B immune globulin

Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines. According to the Centers for Disease Control...
Approved
Investigational
Matched Description: … The preparation is tested for absence of HIV, HCV, herpes virus, and reovirus. ... According to the Centers for Disease Control and Prevention (CDC), the hepatitis B vaccine was the first ... During the process, viruses are deactivated, and in the final steps, solvents used in the preparation …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use …
Matched Products: … Niuliva Solution For Infusion 250 I.U./ml ... HEPATECT CP SOLUTION FOR INFUSION 50 IU/ML ... ZUTECTRA SOLUTION FOR INJECTION 500 IU/ML …

Nifuroxazide

Experimental
Matched Mixtures name: … METRO FORT …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … DIAFURYL FORT 200 MG KAPSÜL, 16 ADET ... DIAFURYL FORT 200 MG KAPSÜL, 24 ADET …

Technetium Tc-99m sestamibi

Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile (MIBI) ligands, hence the name sesta (6) MIBI.. Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by...
Approved
Investigational
Matched Description: … for: 1) detecting coronary artery disease by localizing myocardial ischemia (reversible defects) and ... infarction (non-reversible defects); and 2) evaluating myocardial function and developing information ... intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by the myocardium, parathyroid, and …
Matched Categories: … Indicators and Reagents …
Matched Products: … Kit for the Preparation of Technetium Tc99m Sestamibi …

Nefopam

Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation.
Approved
Investigational
Matched Description: … Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. ... Nefopam has been investigated for the prevention of Kidney Transplantation. …
Matched Products: … ACUPAN SOLUTION FOR INJECTION 20MG/2ML …

Pyrophosphoric acid

Approved
Experimental
Matched Mixtures name: … Phosphotec …
Matched Salts name: … Sodium pyrophosphate ... Sodium pyrophosphate decahydrate …
Matched Categories: … Phosphate salts …
Matched Products: … TECHNESCAN PYP, KIT FOR RADIOPHARMACEUTICAL PREPARATION, 20MG/VIAL …

Human cytomegalovirus immune globulin

Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of antibody for cytomegalovirus (CMV). It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label]. Cytomegalovirus, a member of the herpes virus family, is ubiquitous the human population, leading to infections which are followed by life-long...
Approved
Matched Description: … CMV infection can lead to a high fever and severe organ-specific damage with significant morbidity and ... antibody for cytomegalovirus (CMV). ... vaginal excretions, semen, breast milk and blood [L2228]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use …
Matched Products: … MEGALOTECT CP SOLUTION FOR INFUSION 100 U/ML …

Fomepizole

Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
Approved
Vet approved
Matched Description: … alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and …
Matched Products: … Fomepizole for Injection …

Ropivacaine

Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Approved
Matched Description: … It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the …
Matched Products: … ROPIVACAINE-AFT SOLUTION FOR INJECTION 1% W/V ... ROPIVACAINE-AFT SOLUTION FOR INFUSION 0.2% W/V ... ROPIVACAINE-AFT SOLUTION FOR INJECTION 0.2% W/V …

Methylnaltrexone

Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. It is also a weak CYP2D6 inhibitor. FDA approved in 2008.
Approved
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Constipation …
Matched Products: … Relistor Solution For Injection 12mg/0.6mL …

Amphotericin B

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While...
Approved
Investigational
Matched Description: … The antibiotic is without effect on bacteria, rickettsiae, and viruses. ... Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and ... Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Antimycotics for Systemic Use …
Matched Products: … AMPHOTRET FOR INJECTION USP 50MG ... Amphotericin B for Injection, USP ... AMBISOME FOR INJECTION 50 mg/vial …

Dactinomycin

A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin...
Approved
Investigational
Matched Description: … It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … DACTINOMYCIN FOR INJECTION 0.5 mg/vial …

Cholestyramine

Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water.
Approved
Investigational
Matched Categories: … Hypolipidemic Agents Indicated for Hyperlipidemia ... Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia …
Matched Products: … Cholestyramine Powder for Suspension ... Cholestyramine for Oral Suspension ... PHL-cholestyramine Powder for Suspension 400gm/can …

Spectinomycin

An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
Approved
Investigational
Vet approved
Matched Description: … It is active against gram-negative bacteria and used for the treatment of gonorrhea. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … TROBICIN FOR INJECTION 2 g/vial …

Peginterferon alfa-2a

Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Description: … 36% for genotype 1 and 59% for genotypes 2-6 after 48 weeks of treatment. ... development of endocrine and autoimmune disorders, retinopathies, cardiovascular and neuropsychiatric ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Treatments for Hepatitis C ... Intercellular Signaling Peptides and Proteins …
Matched Products: … PEGASYS PRE-FILLED SYRINGE FOR INJECTION 180 mcg/0.5 ml ... PEGASYS PRE-FILLED SYRINGE FOR INJECTION 135 mcg/0.5 ml …

Dulaglutide

Dulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and exercise in the management of 2 diabetes (T2DM). Dulaglutide was initially approved by the FDA in 2014, and...
Approved
Investigational
Matched Description: … [A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for ... use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular ... agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Trulicity 1.5mg solution for injection in pre-filled pen ... Trulicity 0.75mg solution for injection in pre-filled pen …

Fosaprepitant

Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Approved
Matched Description: … It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment …
Matched Categories: … Aprepitant and Prodrugs …
Matched Products: … Powder for Solution for Infusion 150mg …

Cloprostenol

Vet approved
Matched Salts name: … Cloprostenol sodium …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Matched Products: … GESTAVET PROST (d-cloprostenol 75 mcg/ml solution for injection) …

2-Acetyl-3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-4-Methyl-5-(4,6,6-Trihydroxy-3,5-Dioxa-4,6-Diphosphahex-1-Yl)Thiazolium Inner Salt P,P'-Dioxide

Experimental
Matched Name: … 5-Pyrimidinyl)Methyl]-4-Methyl-5-(4,6,6-Trihydroxy-3,5-Dioxa-4,6-Diphosphahex-1-Yl)Thiazolium Inner Salt …
Displaying drugs 1576 - 1600 of 1858 in total