Displaying drugs 1601 - 1625 of 2919 in total
Aminopterin
Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment of pediatric leukemia. In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment...
Investigational
Withdrawn
Matched Synonyms: … 4-aminofolic acid ... 4-aminopteroylglutamic acid ... N-(4-(((2,4-diamino-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid …
Matched Iupac: … (2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid …
Matched Description: … Clinicians need to be aware of the characteristic teratologic effects of aminopterin and methotrexate ... Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the …
Matched Categories: … Folic Acid Antagonists …
Matched Iupac: … (2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid …
Matched Description: … Clinicians need to be aware of the characteristic teratologic effects of aminopterin and methotrexate ... Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the …
Matched Categories: … Folic Acid Antagonists …
3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid
Experimental
Matched Synonyms: … 3-deoxy-α-D-manno-oct-2-ulopyranosonic acid ... α-2-keto-3-deoxyoctulosonic acid pyranose …
Matched Name: … 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid …
Matched Iupac: … (2R,4R,5R,6R)-6-[(1R)-1,2-dihydroxyethyl]-2,4,5-trihydroxyoxane-2-carboxylic acid …
Matched Name: … 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid …
Matched Iupac: … (2R,4R,5R,6R)-6-[(1R)-1,2-dihydroxyethyl]-2,4,5-trihydroxyoxane-2-carboxylic acid …
alpha,beta-Dehydroaminobutyric acid
Experimental
Matched Synonyms: … (Z)-2-aminobutenoic acid ... (2Z)-2-aminobut-2-enoic acid …
Matched Name: … alpha,beta-Dehydroaminobutyric acid …
Matched Iupac: … (2Z)-2-aminobut-2-enoic acid …
Matched Name: … alpha,beta-Dehydroaminobutyric acid …
Matched Iupac: … (2Z)-2-aminobut-2-enoic acid …
Hydroxyurea
Hydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928. It was first approved by the FDA in 1998 for the treatment of sickle cell anemia in adults. Although clinical evidence on the efficacy of hydroxyurea in certain conditions exists, hydroxyurea...
Approved
Matched Synonyms: … Carbamohydroxamic acid ... Carbamohydroximic acid …
Matched Description: … adherence, the need for therapeutic monitoring, and serious side effects of secondary cancer and birth ... conditions exists, hydroxyurea is used sparingly in clinical settings, largely due to lack of knowledge and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Matched Description: … adherence, the need for therapeutic monitoring, and serious side effects of secondary cancer and birth ... conditions exists, hydroxyurea is used sparingly in clinical settings, largely due to lack of knowledge and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Cefalotin
Cefalotin is a cephalosporin antibiotic.
Approved
Investigational
Vet approved
Matched Synonyms: … 7-(2-Thienylacetamido)cephalosporanic acid ... 7-(2'-thienylacetamido)cephalosporanic acid ... 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid …
Matched Iupac: … acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Sulfur Compounds …
Matched Iupac: … acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Sulfur Compounds …
9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid
Experimental
Matched Name: … 9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid …
Matched Iupac: … 9-hydroxy-8-methoxy-6-nitro-2H-phenanthro[3,4-d][1,3]dioxole-5-carboxylic acid …
Matched Iupac: … 9-hydroxy-8-methoxy-6-nitro-2H-phenanthro[3,4-d][1,3]dioxole-5-carboxylic acid …
1,8-Di-Hydroxy-4-Nitro-Anthraquinone
Experimental
Matched Name: … 1,8-Di-Hydroxy-4-Nitro-Anthraquinone …
Matched Iupac: … 4,5-dihydroxy-1-nitro-9,10-dihydroanthracene-9,10-dione …
Matched Iupac: … 4,5-dihydroxy-1-nitro-9,10-dihydroanthracene-9,10-dione …
Bromfenac
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … 2-amino-3-(4-bromobenzoyl)benzeneacetic acid ... [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid …
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid …
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid …
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Doranidazole
Investigational
Matched Synonyms: … 1,2,4-butanetriol, 3-((2-nitro-1h-imidazol-1-yl)methoxy)-, (2r,3s)-rel- …
Matched Iupac: … (2R,3S)-3-[(2-nitro-1H-imidazol-1-yl)methoxy]butane-1,2,4-triol …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nitro Compounds …
Matched Iupac: … (2R,3S)-3-[(2-nitro-1H-imidazol-1-yl)methoxy]butane-1,2,4-triol …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nitro Compounds …
Isoniazid
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Synonyms: … Isonicotinic acid hydrazide ... Pyridine-4-carboxylic acid hydrazide …
Matched Categories: … Acids, Heterocyclic ... Isonicotinic Acids ... Fatty Acid Synthesis Inhibitors ... ethambutol and isoniazid ... rifampicin and isoniazid …
Matched Categories: … Acids, Heterocyclic ... Isonicotinic Acids ... Fatty Acid Synthesis Inhibitors ... ethambutol and isoniazid ... rifampicin and isoniazid …
Felbamate
Felbamate is an anticonvulsant drug used in the treatment of epilepsy. In particular, in the adult patient population, it can be employed to treat partial seizures (with and without generalization). Alternatively, it is used to treat partial and generalized seizures associated with Lennox-Gastaut syndrome in children. It has a weak...
Approved
Matched Synonyms: … carbamic acid 2-phenyltrimethylene ester ... Carbamic acid 3-carbamoyloxy-2-phenyl-propyl ester …
Matched Description: … In particular, in the adult patient population, it can be employed to treat partial seizures (with and ... Alternatively, it is used to treat partial and generalized seizures associated with Lennox-Gastaut syndrome …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists …
Matched Description: … In particular, in the adult patient population, it can be employed to treat partial seizures (with and ... Alternatively, it is used to treat partial and generalized seizures associated with Lennox-Gastaut syndrome …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists …
Glycerol 2-phosphate
Experimental
Matched Synonyms: … β-glycerophosphoric acid ... beta-Glycerophosphoric acid …
Matched Iupac: … [(1,3-dihydroxypropan-2-yl)oxy]phosphonic acid …
Matched Iupac: … [(1,3-dihydroxypropan-2-yl)oxy]phosphonic acid …
Magnesium acetate
Approved
Matched Synonyms: … acetic acid magnesium salt ... Acetic acid, magnesium salt (2:1) …
Matched Mixtures name: … Normosol-M and Dextrose ... Normosol-M and Dextrose …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Mixtures name: … Normosol-M and Dextrose ... Normosol-M and Dextrose …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Histidine
An essential amino acid that is required for the production of histamine.
Investigational
Nutraceutical
Matched Synonyms: … (S)-a-Amino-1H-imidazole-4-propanoic acid ... (S)-α-amino-1H-Imidazole-4-propanoic acid ... (S)-alpha-amino-1H-Imidazole-4-propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid …
Matched Description: … An essential amino acid that is required for the production of histamine. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Premasol - sulfite-free (Amino Acid) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Essential ... Proteinogenic Amino Acids …
Matched Iupac: … (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid …
Matched Description: … An essential amino acid that is required for the production of histamine. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Premasol - sulfite-free (Amino Acid) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Essential ... Proteinogenic Amino Acids …
Tranilast
Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. In 1982, it was approved in Japan and South Korea for the management of bronchial asthma. Indications for keloid and hypertrophic scar were added in 1993. It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis...
Investigational
Matched Synonyms: … N-(3,4-Dimethoxycinnamoyl)anthranilic acid …
Matched Iupac: … 2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enamido]benzoic acid …
Matched Description: … Indications for keloid and hypertrophic scar were added in 1993. ... In 1982, it was approved in Japan and South Korea for the management of bronchial asthma. ... It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … 2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enamido]benzoic acid …
Matched Description: … Indications for keloid and hypertrophic scar were added in 1993. ... In 1982, it was approved in Japan and South Korea for the management of bronchial asthma. ... It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Acids, Carbocyclic ... Carboxylic Acids …
Metadoxine
Experimental
Matched Synonyms: … Pyridoxine mixture with Pyrrolidonecarboxylic Acid …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid; 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Amino Acids, Acidic ... Amino Acids …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid; 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Amino Acids, Acidic ... Amino Acids …
YS-ON-001
YS-ON-001 is a combination of an inactivated purified rabies virus (IPRV) and the PIKA adjuvant (Poly I:C, kanamycin and calcium).
Investigational
Matched Synonyms: … Polyinosinic-polycytidylic acid/inactivated rabies virus …
Matched Description: … I:C, kanamycin and calcium). ... YS-ON-001 is a combination of an inactivated purified rabies virus (IPRV) and the PIKA adjuvant (Poly …
Matched Description: … I:C, kanamycin and calcium). ... YS-ON-001 is a combination of an inactivated purified rabies virus (IPRV) and the PIKA adjuvant (Poly …
Alminoprofen
Alminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances.
Experimental
Matched Synonyms: … p-((2-Methylallyl)amino)hydratropic acid ... 2-{4-[(2-methylprop-2-en-1-yl)amino]phenyl}propionic acid ... α-methyl-4-[(2-methyl-2-propenyl)amino]benzeneacetic acid …
Matched Iupac: … 2-{4-[(2-methylprop-2-en-1-yl)amino]phenyl}propanoic acid …
Matched Description: … anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
Matched Iupac: … 2-{4-[(2-methylprop-2-en-1-yl)amino]phenyl}propanoic acid …
Matched Description: … anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
(2S)-2-Methyl-3-phenylpropanoic acid
Experimental
Matched Synonyms: … (S)-2-Benzylpropanoic acid …
Matched Name: … (2S)-2-Methyl-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-methyl-3-phenylpropanoic acid …
Matched Name: … (2S)-2-Methyl-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-methyl-3-phenylpropanoic acid …
Fluorescin
Experimental
Matched Synonyms: … 2-(3,6-dihydroxyxanthen-9-yl)benzoic acid …
Matched Iupac: … 2-(3,6-dihydroxy-9H-xanthen-9-yl)benzoic acid …
Matched Iupac: … 2-(3,6-dihydroxy-9H-xanthen-9-yl)benzoic acid …
Monensin
Monensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds.
Experimental
Vet approved
Matched Synonyms: … Monensic acid …
Matched Iupac: … '-bioxolan]-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-methoxy-2-methylpentanoic acid …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … '-bioxolan]-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-methoxy-2-methylpentanoic acid …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Piroxicam cinnamate
Experimental
Matched Synonyms: … Piroxicam cinnamic acid ester …
Matched Categories: … Sulfur Compounds …
Matched Categories: … Sulfur Compounds …
NCX-1000
NCX-1000 is under investigation in clinical trial NCT00414869 (Preliminary Efficacy and Tolerability of NCX-1000 After Repeated Oral Doses in Patients With Elevated Portal Pressure).
Investigational
Matched Synonyms: … No-ursodeoxycholic acid …
Matched Description: … NCX-1000 is under investigation in clinical trial NCT00414869 (Preliminary Efficacy and Tolerability …
Matched Categories: … Bile Acids and Salts ... Cholic Acids …
Matched Description: … NCX-1000 is under investigation in clinical trial NCT00414869 (Preliminary Efficacy and Tolerability …
Matched Categories: … Bile Acids and Salts ... Cholic Acids …
Treamid
Treamid, also known as bisamide derivative of dicarboxylic acid (BDDA), is a complexing agent that has been found to chelate metal ions, including calcium, copper, iron, magnesium, and zinc. This drug has shown regenerative properties and restoration of the function of various tissues and organs. It is has been investigated...
Investigational
Matched Synonyms: … Bisamide derivative of dicarboxylic acid …
Matched Description: … Treamid, also known as bisamide derivative of dicarboxylic acid (BDDA), is a complexing agent that has ... and organs. ... Pharmacokinetics of Treamid in Healthy Volunteers) and NCT04527354 (Pilot Study to Assess Efficacy and …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Description: … Treamid, also known as bisamide derivative of dicarboxylic acid (BDDA), is a complexing agent that has ... and organs. ... Pharmacokinetics of Treamid in Healthy Volunteers) and NCT04527354 (Pilot Study to Assess Efficacy and …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Podofilox
A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and...
Approved
Matched Synonyms: … Podophyllinic acid lactone …
Matched Description: … and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. ... It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. ... It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Description: … and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. ... It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. ... It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts …
Matched Categories: … Skin and Mucous Membrane Agents …
Displaying drugs 1601 - 1625 of 2919 in total