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Displaying drugs 1601 - 1625 of 1920 in total

Alogliptin

Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Description: … Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (> …
Matched Mixtures name: … Alogliptin and Metformin Hydrochloride ... Alogliptin and Pioglitazone ... Alogliptin and Metformin Hydrochloride …
Matched Categories: … Protease Inhibitors ... Alimentary Tract and Metabolism ... metformin and alogliptin ... pioglitazone and alogliptin ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Nesina 25mg Film-Coated Tablet ... Nesina 6.25mg Film-Coated Tablet ... Nesina 12.5mg Film-Coated Tablet …

Ramelteon

Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.
Approved
Investigational
Matched Description: … Ramelteon has not been shown to produce dependence and has shown no potential for abuse. …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … RAMELDA 8 MG FILM KAPLI TABLET,30 ADET ... RAMELDA 8 MG FILM KAPLI TABLET,10 ADET ... ROZEREST 8 MG FİLM KAPLI TABLET, 10 ADET …

Lorlatinib

Lorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer which was first approved by the US FDA in November of 2018. It was subsequently approved by the EMA in 2019 for the treatment of select patients with previously treated advanced ALK-positive...
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … LORVIQUA FILM-COATED TABLET 25MG ... LORVIQUA FILM-COATED TABLET 100MG ... Lorviqua 25 mg Film-Coated Tablets …

Bosutinib

Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine ... BCR-ABL inhibitors like bosutinib inhibit most resistance-conferring BCR-ABL mutations except V299L and ... hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … BOSULİF 500 MG FİLM KAPLI TABLET, 28 ADET ... BOSULİF 500 MG FİLM KAPLI TABLET, 30 ADET ... BOSULİF 100 MG FİLM KAPLI TABLET, 28 ADET …

Ribociclib

Ribociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6). These proteins, when over-activated, can enable cancer cells to grow and divide too quickly. Targeting CDK4/6 with enhanced precision may play...
Approved
Investigational
Matched Description: … These proteins, when over-activated, can enable cancer cells to grow and divide too quickly. ... called cyclin-dependent kinase 4 and 6 (CDK4/6). ... cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression of cancer by inhibiting two proteins …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … KISQALI FILM-COATED TABLET 200MG ... Kryxana 200mg Film-coated Tablets ... VALAMOR 200 MG FİLM KAPLI TABLET, 63 ADET …

Letermovir

Letermovir recieved approval from the FDA on November 8th, 2017 for use in prophylaxis of cytomegalovirus (CMV) infection in allogeneic hematopoietic stem cell transplant patients. It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors. Letermovir has recieved both priority and orphan drug status...
Approved
Investigational
Matched Description: … [A31290] Letermovir has recieved both priority and orphan drug status from the FDA. …
Matched Products: … PREVYMIS FILM COATED TABLET 240MG ... PREVYMIS FILM COATED TABLET 480MG ... PREVYMIS 240MG FILM-COATED TABLET …

Nalmefene

Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Description: … [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist …
Matched Products: … SELINCRO 18MG FILM KAPLI TABLET ,42 TABLET ... SELINCRO 18MG FILM KAPLI TABLET ,7 TABLET ... SELINCRO 18MG FILM KAPLI TABLET ,TABLET, 28 ADET …

Sultamicillin

Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).
Approved
Investigational
Matched Description: … Pneumonia and Chronic Obstructive Pulmonary Disease (COPD). ... Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated …
Matched Categories: … Sulfur Compounds …
Matched Products: … AMPISID 750 MG FILM TABLET, 10 ADET ... AMPİSİD 375 MG FİLM TABLET, 10 ADET ... DEVASID 375 MG FILM TABLET, 20 ADET …

Indapamide

The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. Treatment for hypertension should include a number of lifestyle changes (ie. reduced...
Approved
Matched Description: … The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor ... [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts ... Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension and …
Matched Mixtures name: … BIPRETERAX 10 MG/2.5 MG FİLM KAPLI TABLET, 30 ADET ... TRIPLIXAM FILM COATED TABLET 10 mg/ 2.5 mg/ 5 mg ... BIPRETERAX 5 MG/1,25 MG FILM KAPLI TABLET, 30 ADET …
Matched Categories: … Sulfur Compounds ... Sodium Chloride Symporter Inhibitors ... Genito Urinary System and Sex Hormones ... perindopril, amlodipine and indapamide ... rosuvastatin, perindopril and indapamide …
Matched Products: … FLUPAMID 2.5 MG FİLM TABLET, 30 TABLET ... FLUBEST 2,5 MG FILM KAPLI TABLET, 20 ADET ... FLUDIN 2.5 MG FILM TABLET, 20 ADET …

Cilazapril

Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and...
Approved
Matched Description: … It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries ... Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. …
Matched Mixtures name: … ACEPRIX PLUS 5 MG/12.5 MG FILM TABLET, 30 ADET ... İNHİBACE PLUS 5 MG/12,5 MG FILM KAPLI TABLET, 28 ADET …
Matched Categories: … ACE Inhibitors and Diuretics ... cilazapril and diuretics ... Protease Inhibitors …
Matched Products: … ACEPRIX 1 MG FILM TABLET, 30 ADET ... ACEPRIX 5 MG FILM TABLET, 30 ADET ... ACEPRIX 2.5 MG FILM TABLET, 30 ADET …

Rilpivirine

Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine derivative. The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance...
Approved
Matched Description: … [A31329] The internal conformational flexibility of rilpivirine and the plasticity of it interacting ... [A31331] Rilpivirine was developed by Tilbotec, Inc. and FDA approved on May 20, 2011. ... binding site gives it a very high potency and reduces the chance of resistance compared to other NNRTI's …
Matched Mixtures name: … COMPLERA FILM-COATED TABLET 200MG/25MG/300MG ... ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 90 ADET ... ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 30 ADET …
Matched Categories: … dolutegravir and rilpivirine ... emtricitabine, tenofovir disoproxil and rilpivirine ... emtricitabine, tenofovir alafenamide and rilpivirine …
Matched Products: … EDURANT FILM-COATED TABLET 25 MG ... Edurant 25mg film-coated tablet ... EDURANT 25 MG FILM KAPLI TABLET, 30 ADET …

Ponatinib

Ponatinib is a novel Bcr-Abl tyrosine kinase inhibitor that is especially effective against the T315I mutation for the treatment of chronic myeloid leukemia. FDA approved on December 14, 2012.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … ICLUSIG FILM-COATED TABLET 45 MG ... ICLUSIG FILM-COATED TABLET 15 MG ... ICLUSIG 15 MG FILM-COATED TABLETS …

(3S)-Tetrahydro-3-furanyl {(2S,3S)-4-[(2S,4R)-4-{(1S,2R)-2-[(S)-amino(hydroxy)methoxy]-2,3-dihydro-1H-inden-1-yl}-2-benzyl-3-oxo-2-pyrrolidinyl]-3-hydroxy-1-phenyl-2-butanyl}carbamate

Experimental
Matched Name: … hydroxy)methoxy]-2,3-dihydro-1H-inden-1-yl}-2-benzyl-3-oxo-2-pyrrolidinyl]-3-hydroxy-1-phenyl-2-butanyl}carbamate …
Matched Iupac: … hydroxy)methoxy]-2,3-dihydro-1H-inden-1-yl]-2-benzyl-3-oxopyrrolidin-2-yl]-3-hydroxy-1-phenylbutan-2-yl}carbamate …

Metformin

Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Description: … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management ... It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and ... [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval …
Matched Mixtures name: … PREKO 15/850 MG FILM TABLET, 60 ADET ... PREKO 15/850 MG FILM TABLET, 30 ADET ... PREKO 15/850 MG FILM TABLET, 90 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and ertugliflozin ... metformin and gemigliptin ... metformin and sulfonylureas ... metformin and linagliptin …
Matched Products: … METVEL 850 MG FILM KAPLI TABLET, 50 FILM KAPLI TABLET ... METVEL 850 MG FILM KAPLI TABLET, 100 FILM KAPLI TABLET ... METVEL 1000 MG FILM KAPLI TABLET , 100 FILM KAPLI TABLET …

Sibeprenlimab

Sibeprenlimab is under investigation in clinical trial NCT05248659 (Phase 2/3 Open-label Trial of Sibeprenlimab in the Treatment of Immunoglobulin a Nephropathy).
Investigational
Matched Synonyms: … Immunoglobulin g2, anti-(human proliferation-inducing ligand protein) (human monoclonal vis649 .gamma …

Fimasartan

Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the...
Investigational
Matched Description: … is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and ... Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the brand …
Matched Mixtures name: … ARAHKOR - PRE …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... fimasartan and diuretics ... Angiotensin II receptor blockers (ARBs) and diuretics ... fimasartan and amlodipine ... rosuvastatin and fimasartan …
Matched Products: … Kanarb Film-Coated Tablets 60mg ... Kanarb Film-Coated Tablets 120mg ... KANARB®PLUS FILM COATED TABLETS 60 MG/12.5 MG …

Osimertinib

Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...
Approved
Matched Description: … where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing and ... Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs ... [A7927] More specifically, deletions around the LREA motif in exon 19 and exon 21 L858R point mutations …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … Tagrisso Film-Coated Tablet 40mg ... Tagrisso Film-Coated Tablet 80mg ... TAGRİSSO 40 MG FİLM KAPLI TABLET …

Gilteritinib

Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group. It is a pyrazinecarboxamide derivative that showed high selectivity to FLT3 preventing the c-Kit -driven myelosuppression observed in other...
Approved
Investigational
Matched Description: … is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and ... [A40044] Gilteritinib was developed by Astellas Pharma and FDA approved on November 28, 2018. ... This drug was approved after being designed as an orphan drug with a fast track and priority review status …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … XOSPATA® FILM-COATED TABLETS 40MG ... Xospata 40mg Film Coated Tablets ... XOSPATA 40 MG FİLM KAPLI TABLET, 84 ADET …

Trimetazidine

Trimetazidine is a piperazine derivative indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies. Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s.[A233255,A233260] Acidic conditions, caused by anaerobic metabolism and fatty acid oxidation, in response...
Approved
Investigational
Matched Description: … to myocardial ischemia, activate sodium-hydrogen and sodium-calcium antiport systems. ... [A233255,A233260] Acidic conditions, caused by anaerobic metabolism and fatty acid oxidation, in response ... [A233215] The increased intracellular calcium decreases contractility. …
Matched Products: … SITOREL MR 35 MG DEĞIŞTIRILMIŞ SALIMLI FILM TABLET,FILM TABLET, 60 ADET ... SITOREL 20 MG FILM TABLET, 60 ADET ... VASOFIX 20 MG FILM TABLET, 60 ADET …

Archexin

Investigational
Matched Synonyms: … 5'-DG-DC-T-DG-DC-DA-T-DG-DA-T-DC-T-DC-DC-T-T-DG-DG-DC-DG-3', SODIUM PHOSPHOTHIOATE …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Valaciclovir

Valaciclovir (valacyclovir), also known as Valtrex, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline . Valacyclovir is the L-valine ester of aciclovir. It...
Approved
Investigational
Matched Description: … Valaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and ... It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. ... This class of drugs forms an important part of hepatitis, HIV, and cytomegalovirus drug regimens [A175900 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acyclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … VIROMED 500 MG FILM TABLET,10 ADET ... VIROMED 500 MG FILM TABLET,42 ADET ... VIROMED 1000 MG FILM TABLET,21 TABLET …

Varenicline

Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full...
Approved
Investigational
Matched Description: … Chantix, has been associated with seizures and that some patients who drink while taking the drug may ... In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. ... Food and Drug Administration warned that Varenicline, in the form of Pfizer Inc's quit-smoking drug, …
Matched Mixtures name: … CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 1 MG FILM KAPLI TABLET, 11 VE 14 ADET …
Matched Products: … CHAMPIX 0.5MG FILM-COATED TABLETS ... CHAMPIX 1.0MG FILM-COATED TABLETS ... CHAMPIX 1 MG FILM KAPLI TABLET, 28 ADET …

Acyclovir

Acyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis.[L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. Acyclovir was granted FDA...
Approved
Matched Description: … analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and ... L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and …
Matched Salts name: … Acyclovir sodium …
Matched Categories: … Acyclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … Acyclovir Sodium ... Acyclovir Sodium Injection ... Acyclovir Sodium for Injection …

Sertindole

Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. It is a phenylindole derivative used in the treatment of schizophrenia. It was first marketed in 1996 in several European countries before being withdrawn two years later because of...
Approved
Investigational
Withdrawn
Matched Description: … It has once again been approved and should soon be available on the French and Australian market. …
Matched Products: … SERDOLECT 4 MG FILM KAPLI TABLET, 30 ADET ... SERDOLECT 12 MG FILM KAPLI TABLET, 28 ADET ... SERDOLECT 16 MG FILM KAPLI TABLET, 28 ADET …

Desloratadine

Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Approved
Investigational
Matched Description: … Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral ... Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter …
Matched Mixtures name: … LORCLAST 5 MG/10 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 30 ADET ... DESMONT 5/10 MG 90 FILM KAPLI TABLET ... AIRCOMB 5/10 MG FILM KAPLI TABLET, 30 ADET …
Matched Categories: … Loratadine and derivatives …
Matched Products: … AXIVOL 5 MG FILM TABLET, 10 ADET ... AXIVOL 5 MG FILM TABLET, 30 ADET ... DESADYNE 5 MG FILM TABLET, 30 ADET …
Displaying drugs 1601 - 1625 of 1920 in total