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Displaying drugs 1676 - 1700 of 2451 in total
Enrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use. Due to the identification of fluoroquinolone-resistant strains of Campylobacter, in September 2005, the FDA withdrew the approval of enrofloxacin for its use in water to treat...
Vet approved
Matched Categories: … Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) …
The active metabolite of the prodrug quinapril.
Experimental
Matched Categories: … Enzyme Inhibitors ... Protease Inhibitors ... Angiotensin-Converting Enzyme Inhibitors
Interferon alfa-2c is under investigation in clinical trial NCT00485563 (A Phase II Study of EC17 (Folate-hapten Conjugate) in Patients With Progressive Metastatic Renal Cell Carcinoma).
Investigational
Matched Categories: … Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) …
Silibinin is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin and others. Silibinin is presented as a mixture of two diastereomers, silybin A and silybin B, which are found in an approximately equimolar...
Experimental
Investigational
Matched Categories: … UGT1A1 Inhibitors ... OATP1B3 inhibitors ... OAT1/SLC22A6 inhibitors ... OATP1B1/SLCO1B1 Inhibitors ... Organic Anion Transporting Polypeptide 2B1 Inhibitors
A synthetic fluoroquinolone (FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
Experimental
Matched Categories: … OCT2 Inhibitors
Investigational
Matched Categories: … Topoisomerase Inhibitors
AZD1480 has been used in trials studying the treatment of Solid Malignancies, Post-Polycythaemia Vera, Primary Myelofibrosis (PMF), and Essential Thrombocythaemia Myelofibrosis.
Investigational
Matched Categories: … Janus Kinase 2, antagonists & inhibitors ... Janus Kinases, antagonists & inhibitors
Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Investigational
Matched Categories: … Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) …
Investigational
Matched Categories: … Enzyme Inhibitors ... Poly(ADP-ribose) Polymerase Inhibitors
Parsaclisib is under investigation in clinical trial NCT03126019 (An Open-Label Study of Parsaclisib in Relapsed or Refractory Follicular Lymphoma (CITADEL-203)).
Investigational
Matched Categories: … Protein Kinase Inhibitors ... Phosphatidylinositol-3-kinase (Pi3K) inhibitors
Experimental
Matched Categories: … Enzyme Inhibitors ... Monoamine Oxidase Inhibitors ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
99mTc-Ciprofloxacin is a new formulation of ciprofloxacin (INFECTON), being investigated as a radioimaging agent for the potential diagnosis of infection, including fever of unknown origin, osteomyelitis, wound infection, abdominal abscess, pneumonia, appendicitis and tuberculosis. INFECTON combines the widely used antibiotic, ciprofloxacin, with Technetium ((99m)Tc), the most commonly used radioisotope in...
Investigational
Matched Categories: … Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP1A2 Inhibitors (strong) …
Simendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure).
Investigational
Matched Categories: … Enzyme Inhibitors ... Phosphodiesterase Inhibitors ... Phosphodiesterase 3 Inhibitors
Polmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Localized Primary Osteoarthritis of Hip, and Localized Primary Osteoarthritis of Knee.
Investigational
Matched Categories: … COX-2 Inhibitors ... Cyclooxygenase Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Lobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
Investigational
Matched Categories: … Enzyme Inhibitors ... Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors
Experimental
Matched Categories: … Enzyme Inhibitors ... Histone Deacetylase Inhibitors
A potent inhibitor of membrane metalloendopeptidase (enkephalinase). Thiorphan potentiates morphine-induced analgesia and attenuates naloxone-precipitated withdrawal symptoms.
Experimental
Matched Categories: … Enzyme Inhibitors ... Protease Inhibitors
IPI-493 has been used in trials studying the treatment of Advanced Malignancies.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors ... Protein-Serine-Threonine Kinases, antagonists & inhibitors
Delpazolid (LCB01-0371) is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Synthesis Inhibitors
Distigmine is a parasympathomimetic agent with a longer duration of action and enhanced drug accumulation compared to DB00545 and DB01400. It is an anticholinergic drug and long-acting reversible carbamate cholinesterase inhibitor that binds directly and competitively to the agonist binding sites of muscurinic receptors. Distigmine is available in several countries...
Experimental
Matched Categories: … Enzyme Inhibitors ... Cholinesterase Inhibitors
Imetelstat is under investigation in clinical trial NCT01916187 (Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastoma).
Investigational
Matched Categories: … Enzyme Inhibitors ... Telomerase, antagonists & inhibitors
Branebrutinib is under investigation in clinical trial NCT02705989 (Safety, Tolerability and Relative Bioavailability Study of BMS-986195 in Healthy Subjects).
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors
Alflutinib is under investigation in clinical trial NCT03452592 (Efficacy and Safety of Alflutinib in Locally Advanced or Metastatic Non-small Cell Lung Cancer Patients With T790M).
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors
Nedisertib is under investigation in clinical trial NCT03770689 (Study of M3814 in Combination With Capecitabine and Radiotherapy in Rectal Cancer).
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors
Tofisopam (marketed under brand names Emandaxin and Grandaxin) is a 2,3-benzodiazepine drug which is a benzodiazepine derivative. In contrast to classical 1,4-benzodiazepines, the compound does not bind to the benzodiazepine binding site of the gamma-aminobutyric acid receptor and its psychopharmacological profile differs from such compounds. Although Tofisopam is not approved...
Experimental
Matched Categories: … Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Displaying drugs 1676 - 1700 of 2451 in total