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Displaying drugs 151 - 175 of 284 in total
Enzalutamide is an androgen receptor (AR) inhibitor for the treatment of castration-resistant prostate cancer (CRPC), both metastatic and non-metastatic. It is a second-generation antiandrogen agent that the FDA approved on August 31, 2012.[L40639, A252667] Although androgen deprivation therapy (ADT) is the first-line treatment of prostate cancer and remission can be...
Approved
Nelfinavir is a potent HIV-1 protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children. Nelfinavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.
Approved
Icatibant is a synthetic decapeptide with 5 nonproteinogenic amino acid antagonist targeting the B2 receptors with a similar affinity to bradykinin. It is resistant to bradykinin-cleaving enzyme degradation and has a potency of 2-3 times higher than earlier B2 receptors antagonists, thus representing a new class of medication.[A4017,A263041] It was...
Approved
Investigational
Pitavastatin, also known as the brand name product Livalo, is a lipid-lowering drug belonging to the statin class of medications. By inhibiting the endogenous production of cholesterol within the liver, statins lower abnormal cholesterol and lipid levels and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively...
Approved
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein, CD52. The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and complementarity-determining regions from a...
Approved
Investigational
Lorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer which was first approved by the US FDA in November of 2018. It was subsequently approved by the EMA in 2019 for the treatment of select patients with previously treated advanced ALK-positive...
Approved
Investigational
Aluminum (Al), also spelled aluminum, chemical element, a lightweight, silvery-white metal of main Group 13 (IIIa, or boron group) of the periodic table . It is a chemical agent used in water purification, the pH regulation of garden soil, and other commercial or industrial applications. Medically, it is primarily used...
Approved
Etrasimod is a synthetic next-generation selective Sphingosine 1-phosphate (S1P) receptor modulator that targets the S1P1,4,5 with no detectable activity on S1P2 and S1P3 receptors. S1P receptors are membrane-derived lysophospholipid signaling molecules that are involved in the sequestration of circulating peripheral lymphocytes in lymph nodes. Therefore, S1P receptor modulators like etrasimod...
Approved
Zuranolone is a neuroactive steroid that acts as a positive allosteric modulator of the GABAA receptors. Unlike other more common GABAA positive allosteric modulators on the market like benzodiazepines, zuranolone can modulate both synaptic and extrasynaptic GABAA conductance due to binding to a non-benzodiazepine site on the receptor.[A260776,A260786] Zuranolone was...
Approved
Experimental
Zinc oxide is an inorganic compound used in a number of manufacturing processes. It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes. It occurs naturally as the mineral zincite, but most zinc oxide is produced...
Approved
Matched Products: … Whole Body Organic Sunscreen …
Also known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other...
Approved
Investigational
Matched Mixtures name: … Queens Rose Whole In One Sunblock …
Pisum sativum whole allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Garden pea whole ... Pisum album whole ... Pisum arvense whole
Matched Name: … Pisum sativum whole
Matched Description: … Pisum sativum whole allergenic extract is used in allergenic testing. …
Lactuca sativa whole allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Lettuce whole ... Garden lettuce whole ... Lactuca crispa whole
Matched Name: … Lactuca sativa whole
Matched Description: … Lactuca sativa whole allergenic extract is used in allergenic testing. …
Rumex crispus whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Sour Dock Whole ... Curled Dock Whole ... Curly Dock Whole
Matched Name: … Rumex crispus whole
Matched Description: … Rumex crispus whole is a plant/plant extract used in some OTC (over-the-counter) products. …
Pinus sylvestris pollen is the pollen of the Pinus sylvestris plant. Pinus sylvestris pollen is mainly used in allergenic testing.
Approved
Matched Name: … Pinus sylvestris pollen …
Matched Description: … Pinus sylvestris pollen is the pollen of the Pinus sylvestris plant. ... Pinus sylvestris pollen is mainly used in allergenic testing. …
Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Synonyms: … Bacopa Whole ... Brahmi Whole ... Gotu Kola Whole
Sarracenia purpurea, commonly known as the purple pitcher plant, northern pitcher plant, turtle socks, or side-saddle flower, is a perennial carnivorous plant in the family Sarraceniaceae. Sarracenia purpurea attract and trap insects within their pitchers, or fused leaves, to consume nitrogen during the digestion process . It is widely distributed...
Approved
Experimental
Matched Synonyms: … Pitcherplant whole ... Frog's-britches whole ... Huntsman's-horns whole
Approved
Matched Synonyms: … Bacillus tetani whole ... Clostridium tetani whole
Camponotus pennsylvanicus allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Black carpenter ant whole ... Camponotus pennsylvanicus whole
Absidia capillata allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Absidia capillata whole
Cow milk allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Milk,whole dry ... Bos taurus milk whole
Matched Products: … Food - Dairy Products, Milk, Whole Cow …
Mycogone nigra allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Mycogone nigra whole
Fusarium oxysporum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Fusarium oxysporum whole
Usnea barbata is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Usnea Barbata Whole
Displaying drugs 151 - 175 of 284 in total