Displaying drugs 1776 - 1800 of 2865 in total
2,6-anhydro-3-deoxy-3-fluoronononic acid
Experimental
Matched Synonyms: … 3-deoxy-3-fluoro-D-erythro-α-L-manno-non-2-ulopyranosonic acid …
Matched Name: … 2,6-anhydro-3-deoxy-3-fluoronononic acid …
Matched Iupac: … (2R,3R,4R,5R,6S)-3-fluoro-2,4,5-trihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
Matched Name: … 2,6-anhydro-3-deoxy-3-fluoronononic acid …
Matched Iupac: … (2R,3R,4R,5R,6S)-3-fluoro-2,4,5-trihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
COTI-2
Investigational
Matched Synonyms: … 1-piperazinecarbothioic acid, 4-(2-pyridinyl)-, 2-(6,7-dihydro-8(5h)-quinolinylidene)hydrazide …
Valopicitabine
The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Synonyms: … 2'-C-methylcytidine 3'-O-L-valinyl ester …
Matched Description: … This blocks viral production of HCV RNA and thus viral replication. [from NCI] ... upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and ... The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … This blocks viral production of HCV RNA and thus viral replication. [from NCI] ... upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and ... The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Pravastatin
Pravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. This drug was developed by Sankyo Co. Ltd.; however, the first approved...
Approved
Matched Synonyms: … Pravastatin acid ... 8S,8aR)-6-hydroxy-2-methyl-8-{[(S)-2-methylbutyryl]oxy}-1,2,6,7,8,8a-hexahydro-1-naphthyl]heptanoic acid …
Matched Iupac: … methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid …
Matched Description: … Pravastatin is the 6-alpha-hydroxy acid form of [mevastatin]. ... It was the first statin administered as the active form and not as a prodrug. ... Ltd.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved …
Matched Categories: … pravastatin and acetylsalicylic acid ... pravastatin and ezetimibe ... pravastatin and fenofibrate ... pravastatin, ezetimibe and fenofibrate …
Matched Iupac: … methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid …
Matched Description: … Pravastatin is the 6-alpha-hydroxy acid form of [mevastatin]. ... It was the first statin administered as the active form and not as a prodrug. ... Ltd.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved …
Matched Categories: … pravastatin and acetylsalicylic acid ... pravastatin and ezetimibe ... pravastatin and fenofibrate ... pravastatin, ezetimibe and fenofibrate …
Lymecycline
Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy. Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK...
Approved
Investigational
Matched Synonyms: … Tetracycline-L-methylene lysine ... 5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamido)methyl)lysine …
Matched Iupac: … methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracen-2-yl]formamido}methyl)amino]-2-aminohexanoic acid …
Matched Description: … Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and ... has been proven a cost-effective alternative to treatment with [minocycline] with comparable safety and ... It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. …
Matched Iupac: … methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracen-2-yl]formamido}methyl)amino]-2-aminohexanoic acid …
Matched Description: … Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and ... has been proven a cost-effective alternative to treatment with [minocycline] with comparable safety and ... It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. …
Nifedipine
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Description: … developed with slower onsets and longer durations of action. ... [A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature ... [A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been …
Matched Categories: … Beta blocking agents and calcium channel blockers ... Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... atenolol and nifedipine ... nifedipine and diuretics …
Matched Products: … NIFEDIPIN ACIS 10MG RETARD ... NIFEDIPIN ACIS 20MG RETARD …
Matched Categories: … Beta blocking agents and calcium channel blockers ... Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... atenolol and nifedipine ... nifedipine and diuretics …
Matched Products: … NIFEDIPIN ACIS 10MG RETARD ... NIFEDIPIN ACIS 20MG RETARD …
Ralinepag
Ralinepag has been used in trials studying the treatment of Pulmonary Arterial Hypertension.
Investigational
Matched Synonyms: … 2-{[(1r,4r)-4-(((4-chlorophenyl)(phenyl)carbamoyloxy)methyl)cyclohexy]methoxy} acetic acid …
Matched Iupac: … 2-{[(1r,4r)-4-({[(4-chlorophenyl)(phenyl)carbamoyl]oxy}methyl)cyclohexyl]methoxy}acetic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … 2-{[(1r,4r)-4-({[(4-chlorophenyl)(phenyl)carbamoyl]oxy}methyl)cyclohexyl]methoxy}acetic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Indralin
Investigational
Matched Synonyms: … 2-thiophenecarboxylic acid, 5-((1e)-2-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-propen ... 1e)-2-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-propen-1-yl)-2-thiophenecarboxylic acid …
Matched Iupac: … 1E)-2-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]thiophene-2-carboxylic acid …
Matched Categories: … Receptors, Retinoic Acid, agonists …
Matched Iupac: … 1E)-2-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]thiophene-2-carboxylic acid …
Matched Categories: … Receptors, Retinoic Acid, agonists …
Telmisartan
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Synonyms: … 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid ... 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid ... 4'-((4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid …
Matched Iupac: … methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}-[1,1'-biphenyl]-2-carboxylic acid …
Matched Mixtures name: … Telmisartan and Hydrochlorothiazide ... Telmisartan and Hydrochlorothiazide ... Telmisartan and Hydrochlorothiazide …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... telmisartan and amlodipine ... telmisartan and diuretics ... rosuvastatin and telmisartan …
Matched Iupac: … methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}-[1,1'-biphenyl]-2-carboxylic acid …
Matched Mixtures name: … Telmisartan and Hydrochlorothiazide ... Telmisartan and Hydrochlorothiazide ... Telmisartan and Hydrochlorothiazide …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... telmisartan and amlodipine ... telmisartan and diuretics ... rosuvastatin and telmisartan …
Cinchocaine
A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
Approved
Vet approved
Matched Synonyms: … α-butyloxycinchonic acid-γ-diethylethylenediamine ... α-butyloxycinchoninic acid diethylethylenediamide ... 2-butoxyquinoline-4-carboxylic acid diethylaminoethylamide …
Matched Description: … It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is …
Matched Categories: … Analgesics and Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antipruritics and Local Anesthetics ... Increased Histamine Release …
Matched Description: … It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is …
Matched Categories: … Analgesics and Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antipruritics and Local Anesthetics ... Increased Histamine Release …
Eprosartan
Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Approved
Matched Synonyms: … (E)-2-butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acid ... (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid ... (E)-α{[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazole-5-yl]methylene}-2-thiopheneproprionic acid …
Matched Iupac: … ({2-butyl-5-[(1E)-2-carboxy-2-[(thiophen-2-yl)methyl]eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid …
Matched Description: … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and diuretics ... eprosartan and diuretics ... Acids, Acyclic ... Carboxylic Acids …
Matched Iupac: … ({2-butyl-5-[(1E)-2-carboxy-2-[(thiophen-2-yl)methyl]eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid …
Matched Description: … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and diuretics ... eprosartan and diuretics ... Acids, Acyclic ... Carboxylic Acids …
Fluciclovine (18F)
Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. It presents excellent diagnostic properties to be used in positron emission tomography (PET) imaging. The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid transporter without incorporating in the metabolism within the...
Approved
Matched Synonyms: … (1R,3R)-1-amino-3(18F)fluorocyclobutane-1-carboxylic acid ... Anti-1-amino-3-(18F)fluorocyclobutane-1-carboxylic acid …
Matched Iupac: … (1r,3r)-1-amino-3-(¹⁸F)fluorocyclobutane-1-carboxylic acid …
Matched Description: … Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. ... [A31385] Fluciclovine was developed by Blue Earth Diagnostics, Ltd. and FDA approved in May 27, 2016. ... [A31384] The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid …
Matched Iupac: … (1r,3r)-1-amino-3-(¹⁸F)fluorocyclobutane-1-carboxylic acid …
Matched Description: … Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. ... [A31385] Fluciclovine was developed by Blue Earth Diagnostics, Ltd. and FDA approved in May 27, 2016. ... [A31384] The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid …
Lixisenatide
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Approved
Matched Synonyms: … des-38-proline-exendine-4 (Heloderma suspectum)-(1-39)-peptidylpenta-L-lysyl-L-lysinamide …
Matched Description: … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU. …
Matched Mixtures name: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin glargine and lixisenatide …
Matched Description: … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU. …
Matched Mixtures name: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin glargine and lixisenatide …
Itepekimab
Itepekimab is under investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-il-33 Mab) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)).
Investigational
Matched Synonyms: … Immunoglobulin igg4 (230-proline), anti-(human interleukin 33) (human monoclonal regn3500 .gamma.4-chain …
Matched Description: … investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
L-N(omega)-nitroarginine-(4R)-amino-L-proline amide
Experimental
Matched Name: … L-N(omega)-nitroarginine-(4R)-amino-L-proline amide …
N-(dibenzo[b,d]thiophen-3-ylsulfonyl)-L-valine
Experimental
Matched Name: … N-(dibenzo[b,d]thiophen-3-ylsulfonyl)-L-valine …
Matched Iupac: … 3-methyl-2-{8-thiatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,5,9,11-hexaene-5-sulfonamido}butanoic acid …
Matched Iupac: … 3-methyl-2-{8-thiatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,5,9,11-hexaene-5-sulfonamido}butanoic acid …
2-Oxy-4-Hydroxy-5-(2-Hydrazinopyridine)Phenylalanine
Experimental
Matched Name: … 2-Oxy-4-Hydroxy-5-(2-Hydrazinopyridine)Phenylalanine …
Matched Iupac: … -2-amino-3-[(1R)-4-hydroxy-6-oxo-3-[2-(pyridin-2-yl)hydrazin-1-yl]cyclohexa-2,4-dien-1-yl]propanoic acid …
Matched Iupac: … -2-amino-3-[(1R)-4-hydroxy-6-oxo-3-[2-(pyridin-2-yl)hydrazin-1-yl]cyclohexa-2,4-dien-1-yl]propanoic acid …
Fosgemcitabine palabenamide
NUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).
Investigational
Matched Synonyms: … L-ALANINE, N-(2'-DEOXY-2',2'-DIFLUORO-P-PHENYL-5'-CYTIDYLYL)-, PHENYLMETHYL ESTER ... N-[[P(S)]-2'-deoxy-2',2'-difluoro-P-phenyl-5'-cytidylyl]-L-alanine phenylmethyl ester ... L-Alanine, N-[[P(S)]-2'-deoxy-2',2'-difluoro-P-phenyl-5'-cytidylyl]-, phenylmethyl ester …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Aprobarbital
Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects. A primary treatment indicated for the use of aprobarbital was subsequently insomnia. Aprobarbital was never as widely used as more common barbiturate derivatives...
Experimental
Illicit
Matched Synonyms: … 5-allyl-5-isopropylbarbituric acid ... 5-isopropyl-5-allylbarbituric acid …
Matched Description: … It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant ... Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and …
Matched Categories: … Hypnotics and Sedatives …
Matched Description: … It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant ... Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and …
Matched Categories: … Hypnotics and Sedatives …
(S)-AMPA
AMPA is a specific agonist for the AMPA receptor.
Experimental
Matched Synonyms: … (S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid …
Matched Iupac: … (2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl)propanoic acid …
BPH-608
Experimental
Matched Synonyms: … (1-hydroxy-1-phosphono-2-[1,1';3',1'']terphenyl-3-yl-ethyl)-phosphonic acid …
Matched Iupac: … (1-hydroxy-2-{3'-phenyl-[1,1'-biphenyl]-3-yl}-1-phosphonoethyl)phosphonic acid …
Matched Iupac: … (1-hydroxy-2-{3'-phenyl-[1,1'-biphenyl]-3-yl}-1-phosphonoethyl)phosphonic acid …
Tricaprylin
Tricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease.
Investigational
Matched Synonyms: … Caprylic acid triglyceride …
Matched Description: … Tricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
Matched Description: … Tricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
Sodium tartrate
Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and odorless crystals. It is obtained as a byproduct of wine manufacturing. Sodium tartrate is generally recognized as safe (GRAS) as a direct human food ingredient. It acts as an emulsifier and pH...
Approved
Matched Synonyms: … Tartaric acid, disodium salt …
Matched Description: … , and odorless crystals. ... Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless ... It acts as an emulsifier and pH control agent in food products [L2590]. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids …
Matched Description: … , and odorless crystals. ... Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless ... It acts as an emulsifier and pH control agent in food products [L2590]. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids …
Displaying drugs 1776 - 1800 of 2865 in total