Displaying drugs 1801 - 1825 of 3201 in total
Quizartinib
Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug developed specifically targeting FLT3, as other agents with FLT3 inhibition activities were investigated with other targets in mind. Additionally, quizartinib also demonstrates inhibitory activity toward FLT3 with internal tandem duplication (ITD), although...
Approved
Investigational
Brexpiprazole
Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM). It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. Although it is structurally similar to aripiprazole, brexpiprazole has different binding affinities for dopamine and serotonin receptors. Compared...
Approved
Investigational
Bosutinib
Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Pitavastatin
Pitavastatin, also known as the brand name product Livalo, is a lipid-lowering drug belonging to the statin class of medications. By inhibiting the endogenous production of cholesterol within the liver, statins lower abnormal cholesterol and lipid levels and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively...
Approved
Acetyl sulfisoxazole
Sulfisoxazole acetyl is an ester of sulfisoxazole, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme, dihydropteroate synthase, preventing the incorporation of PABA into dihydrofolic acid, which is the precursor of folic acid. This process causes...
Approved
Vet approved
Abametapir
Abametapir is a novel pediculicidal metalloproteinase inhibitor used to treat infestations of head lice. The life cycle of head lice (Pediculus capitis) is approximately 30 days, seven to twelve of which are spent as eggs laid on hair shafts near the scalp. Topical pediculicides generally lack adequate ovicidal activity, including...
Approved
Investigational
Irbesartan
Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.[L7456,L7459] It can also be used as part of a combination product with hydrochlorothiazide for patients not well controlled or not expected to be well controlled on monotherapy. Unlike angiotensin converting enzyme inhibitors, ARBs are not associated...
Approved
Investigational
Ceftolozane
Ceftolozane is a semi-synthetic broad-spectrum fifth generation cephalosporin. It was approved by the FDA in 2014 for use in combination with Tazobactam for the treatment of serious infections, such as intra-abdominal infections and complicated urinary tract infections. The manufacturer of this drug is Cubist Pharmaceuticals. Most recently, in June 2019,...
Approved
Investigational
Triclosan
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items...
Approved
Investigational
Matched Products: … KURSEPT %19 + %1 DERİ ÇÖZELTİSİ, 50 G …
Dextromethorphan
Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Salts cas: … 125-69-9 …
Matched Mixtures name: … VICKS VAPODRY SURUP, 60 ML …
Matched Mixtures name: … VICKS VAPODRY SURUP, 60 ML …
Polysorbate 60
Experimental
Matched International brands: … Tween 60 …
Matched Synonyms: … Polisorbato 60 ... Polysorbata 60 ... Polysorbate 60 …
Matched Name: … Polysorbate 60 …
Matched Synonyms: … Polisorbato 60 ... Polysorbata 60 ... Polysorbate 60 …
Matched Name: … Polysorbate 60 …
9-Aminophenanthrene
Experimental
Matched Synonyms: … 9-phenanthrenamine ... 9-phenanthrylamine ... phenanthren-9-amine …
Matched Name: … 9-Aminophenanthrene …
Matched Iupac: … phenanthren-9-amine …
Matched Name: … 9-Aminophenanthrene …
Matched Iupac: … phenanthren-9-amine …
Cobalt Co-60
Cobalt Co-60 is under investigation in clinical trial NCT02891083 (Adjuvant Therapies or Surgery Alone for High Risk pN0 Esophageal Cancer).
Investigational
Matched Name: … Cobalt Co-60 …
Matched Description: … Cobalt Co-60 is under investigation in clinical trial NCT02891083 (Adjuvant Therapies or Surgery Alone …
Matched Description: … Cobalt Co-60 is under investigation in clinical trial NCT02891083 (Adjuvant Therapies or Surgery Alone …
N-9-Methoxynonyldeoxynojirimycin
Investigational
Matched Synonyms: … 3,4,5-piperidinetriol, 2-(hydroxymethyl)-1-(9-methoxynonyl)-, (2r,3r,4r,5s)- …
Matched Name: … N-9-Methoxynonyldeoxynojirimycin …
Matched Iupac: … (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(9-methoxynonyl)piperidine-3,4,5-triol …
Matched Salts name: … N-9-Methoxynonyldeoxynojirimycin hydrochloride …
Matched Name: … N-9-Methoxynonyldeoxynojirimycin …
Matched Iupac: … (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(9-methoxynonyl)piperidine-3,4,5-triol …
Matched Salts name: … N-9-Methoxynonyldeoxynojirimycin hydrochloride …
9(S)-HODE
Experimental
Matched Synonyms: … (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid …
Matched Name: … 9(S)-HODE …
Matched Iupac: … (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid …
Matched Name: … 9(S)-HODE …
Matched Iupac: … (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid …
S-9-(2-hydroxypropyl)adenine
Experimental
Matched Synonyms: … 9-Hydroxypropyladenine, S-Isomer …
Matched Name: … S-9-(2-hydroxypropyl)adenine …
Matched Iupac: … (2S)-1-(6-amino-9H-purin-9-yl)propan-2-ol …
Matched Name: … S-9-(2-hydroxypropyl)adenine …
Matched Iupac: … (2S)-1-(6-amino-9H-purin-9-yl)propan-2-ol …
R-9-(2-hydroxypropyl)adenine
Experimental
Matched Synonyms: … 9-Hydroxypropyladenine, R-Isomer …
Matched Name: … R-9-(2-hydroxypropyl)adenine …
Matched Iupac: … (2R)-1-(6-amino-9H-purin-9-yl)propan-2-ol …
Matched Name: … R-9-(2-hydroxypropyl)adenine …
Matched Iupac: … (2R)-1-(6-amino-9H-purin-9-yl)propan-2-ol …
AN-9
Pivaloyloxymethyl butyrate (AN-9), an acyloxyalkyl ester prodrug of butyric acid (BA), exhibited low toxicity and significant anticancer activity in vitro and in vivo. It shows greater potency than BA at inducing malignant cell differentiation and tumor growth inhibition and has demonstrated more favorable toxicological, pharmacological, and pharmaceutical properties than BA...
Investigational
Matched Name: … AN-9 …
Matched Description: … Pivaloyloxymethyl butyrate (AN-9), an acyloxyalkyl ester prodrug of butyric acid (BA), exhibited low …
Matched Description: … Pivaloyloxymethyl butyrate (AN-9), an acyloxyalkyl ester prodrug of butyric acid (BA), exhibited low …
9-Methylguanine
Experimental
Matched Name: … 9-Methylguanine …
Matched Iupac: … 2-amino-9-methyl-6,9-dihydro-1H-purin-6-one …
Matched Iupac: … 2-amino-9-methyl-6,9-dihydro-1H-purin-6-one …
9-aminocamptothecin
Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
Investigational
Matched Name: … 9-aminocamptothecin …
Displaying drugs 1801 - 1825 of 3201 in total