Displaying drugs 1801 - 1825 of 2972 in total
Trofinetide
Trofinetide is a novel synthetic analog of glypromate, also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor 1 (IGF-1). Trofinetide was approved by the FDA on March 10, 2023, for the treatment of Rett syndrome,[L45718,L45748] which is an X-linked...
Approved
Investigational
Matched Synonyms: … glycyl-L-2-methylprolyl-L-glutamic acid …
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidin-2-yl]formamido}pentanedioic acid …
Matched Description: … glypromate], also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and ... [A258438] Trofinetide is believed to work by reducing inflammation and apoptosis of neurons. ... L45748] which is an X-linked neurodevelopmental disorder characterized by a range of cognitive, motor, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidin-2-yl]formamido}pentanedioic acid …
Matched Description: … glypromate], also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and ... [A258438] Trofinetide is believed to work by reducing inflammation and apoptosis of neurons. ... L45748] which is an X-linked neurodevelopmental disorder characterized by a range of cognitive, motor, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Ammonium lactate
Ammonium lactate is the ammonium salt of lactic acid.
Approved
Matched Synonyms: … Lactic acid ammonium salt …
Matched Description: … Ammonium lactate is the ammonium salt of lactic acid. …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids ... alpha-Hydroxy Acid …
Matched Description: … Ammonium lactate is the ammonium salt of lactic acid. …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids ... alpha-Hydroxy Acid …
CXA-10
CXA-10 is under investigation in clinical trial NCT03422510 (FIRSTx - A Study of Oral CXA-10 in Primary Focal Segmental Glomerulosclerosis (FSGS)).
Investigational
Matched Synonyms: … 10-nitro-9(E)-octadec-9-enoic acid …
Matched Iupac: … (9E)-10-nitrooctadec-9-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Matched Iupac: … (9E)-10-nitrooctadec-9-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Psoralen
Investigational
Matched Synonyms: … 6-hydroxy-5-benzofuranacrylic acid .delta.-lactone …
Matched Categories: … Indicators and Reagents …
Matched Categories: … Indicators and Reagents …
Vinylglycine
Vinylglycine is an irreversible inhibitor of aspartate aminotransferase.
Experimental
Matched Synonyms: … (2S)-2-amino-3-butenoic acid …
Matched Iupac: … (2S)-2-aminobut-3-enoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … (2S)-2-aminobut-3-enoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
(2R,3R)-2,3-Dihydroxy-4-oxo-4-(propylamino)butanoic acid
Experimental
Matched Synonyms: … N-Propyl-tartramic acid …
Matched Name: … (2R,3R)-2,3-Dihydroxy-4-oxo-4-(propylamino)butanoic acid …
Matched Iupac: … (2R,3R)-2,3-dihydroxy-3-(propylcarbamoyl)propanoic acid …
Matched Name: … (2R,3R)-2,3-Dihydroxy-4-oxo-4-(propylamino)butanoic acid …
Matched Iupac: … (2R,3R)-2,3-dihydroxy-3-(propylcarbamoyl)propanoic acid …
Glypromate
Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 which inhibits caspase III dependent apoptosis, for the potential treatment of neurodegenerative diseases by IV infusion. In December 2008, the company discontinued further development of the drug after it failed to show an observable effect.
Investigational
Matched Synonyms: … Glycyl-prolyl-glutamic acid …
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}pentanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}pentanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Thrombomodulin Alfa
Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism.
Approved
Investigational
Matched Synonyms: … Thrombomodulin (human 498-amino acid fragment) …
Matched Description: … Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). ... It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential ... treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). ... It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential ... treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ascorbyl glucoside
Experimental
Matched Synonyms: … Ascorbic acid 2-O-glucoside …
Matched Categories: … Sugar Acids ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Categories: … Sugar Acids ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids …
Methyl salicylate 2-ethylbutyrate
Experimental
Matched Synonyms: … Salicylic acid, methyl ester, 2-ethylbutyrate …
Recombinant human highly phosphorylated acid alpha-glucosidase
Investigational
Matched Synonyms: … Recombinant human highly phosphorylated acid alpha-glucosidase …
Matched Name: … Recombinant human highly phosphorylated acid alpha-glucosidase …
Matched Name: … Recombinant human highly phosphorylated acid alpha-glucosidase …
Cyclopentolate
A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Approved
Matched International brands: … Bell Pentolate …
Matched Synonyms: … 1-hydroxy-α-phenylcyclopentaneacetic acid 2-(dimethylamino)ethyl ester ... α-(1-hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester ... 2-phenyl-2-(1-hydroxycyclopentyl)ethanoic acid β-(dimethylamino)ethyl ester …
Matched Categories: … Mydriatics and Cycloplegics ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Synonyms: … 1-hydroxy-α-phenylcyclopentaneacetic acid 2-(dimethylamino)ethyl ester ... α-(1-hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester ... 2-phenyl-2-(1-hydroxycyclopentyl)ethanoic acid β-(dimethylamino)ethyl ester …
Matched Categories: … Mydriatics and Cycloplegics ... Acids, Carbocyclic ... Carboxylic Acids …
Cytidine-5'-Monophosphate
A pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase.
Experimental
Matched Synonyms: … Cytidylic acid …
Matched Iupac: … 2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … 2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Sulfate ion
Experimental
Investigational
Matched Synonyms: … Sulfuric acid ion(2-) …
Matched Categories: … Sulfur Acids ... Sulfuric Acids …
Matched Categories: … Sulfur Acids ... Sulfuric Acids …
Amfenac
Experimental
Matched Synonyms: … (2-Amino-3-benzoylphenyl)acetic acid …
Matched Iupac: … 2-(2-amino-3-benzoylphenyl)acetic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Iupac: … 2-(2-amino-3-benzoylphenyl)acetic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Sodium perchlorate
Experimental
Matched Synonyms: … Perchloric acid, sodium salt …
Matched Categories: … Acids ... Acids, Noncarboxylic …
Matched Categories: … Acids ... Acids, Noncarboxylic …
(1-Hydroxy-2-oxopiperidin-3-yl)phosphonic acid
Investigational
Matched Synonyms: … Phosphonic acid, p-(1-hydroxy-2-oxo-3-piperidinyl)- …
Matched Name: … (1-Hydroxy-2-oxopiperidin-3-yl)phosphonic acid …
Matched Iupac: … (1-hydroxy-2-oxopiperidin-3-yl)phosphonic acid …
Matched Name: … (1-Hydroxy-2-oxopiperidin-3-yl)phosphonic acid …
Matched Iupac: … (1-hydroxy-2-oxopiperidin-3-yl)phosphonic acid …
Crisdesalazine
Investigational
Matched Synonyms: … 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)benzoic acid ... Benzoic acid, 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)- …
Matched Iupac: … 2-hydroxy-5-({2-[4-(trifluoromethyl)phenyl]ethyl}amino)benzoic acid …
Matched Iupac: … 2-hydroxy-5-({2-[4-(trifluoromethyl)phenyl]ethyl}amino)benzoic acid …
{[2-Amino-4-oxo-6,7-di(sulfanyl-κS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum
Experimental
Matched Name: … 6,7-di(sulfanyl-κS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate …
Matched Iupac: … 13-molybdatetracyclo[8.7.0.0^{3,8}.0^{11,15}]heptadeca-3(8),4,11(15)-trien-16-yl]methoxy}phosphonic acid …
Matched Iupac: … 13-molybdatetracyclo[8.7.0.0^{3,8}.0^{11,15}]heptadeca-3(8),4,11(15)-trien-16-yl]methoxy}phosphonic acid …
Bexarotene
Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Approved
Investigational
Matched Synonyms: … 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid ... p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid ... 4-[1-(5,6,7,8,-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphtalenyl)ethenyl]benzoic acid …
Matched Iupac: … 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid …
Matched Description: … It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid …
Matched Description: … It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Carbapenem
Investigational
Matched Synonyms: … (5r)-carbapenem-3-carboxylic acid ... (5r)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid ... 1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 7-oxo-, (5r)- …
Balsalazide
Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK.
The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt.
Balsalazide works by deliverying mesalazine...
Approved
Investigational
Matched Synonyms: … (E)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid ... 5-[4-(2-carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid ... (E)-5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid …
Matched Iupac: … 5-[(1E)-2-{4-[(2-carboxyethyl)carbamoyl]phenyl}diazen-1-yl]-2-hydroxybenzoic acid …
Matched Description: … It is sold under the name "Colazal" in the US and "Colazide" in the UK. ... Mesalazine is also known as 5-aminosalicylic acid, or 5-ASA. ... The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids ... Aminosalicylic Acids …
Matched Iupac: … 5-[(1E)-2-{4-[(2-carboxyethyl)carbamoyl]phenyl}diazen-1-yl]-2-hydroxybenzoic acid …
Matched Description: … It is sold under the name "Colazal" in the US and "Colazide" in the UK. ... Mesalazine is also known as 5-aminosalicylic acid, or 5-ASA. ... The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids ... Aminosalicylic Acids …
VK-0214
Investigational
Matched Synonyms: … (((4-(3-benzyl-4-hydroxybenzyl)-3,5-dimethylphenyl)oxy)methyl)phosphonic acid ... ((4-(3-benzyl-4-hydroxybenzyl)-3,5-dimethylphenoxy)methyl)phosphonic acid ... Phosphonic acid, p-((4-((4-hydroxy-3-(phenylmethyl)phenyl)methyl)-3,5-dimethylphenoxy)methyl)- …
Matched Iupac: … ({4-[(3-benzyl-4-hydroxyphenyl)methyl]-3,5-dimethylphenoxy}methyl)phosphonic acid …
Matched Iupac: … ({4-[(3-benzyl-4-hydroxyphenyl)methyl]-3,5-dimethylphenoxy}methyl)phosphonic acid …
2,3-Dihydroxy-Benzoic Acid
Experimental
Matched Name: … 2,3-Dihydroxy-Benzoic Acid …
Matched Iupac: … 2,3-dihydroxybenzoic acid …
Matched Iupac: … 2,3-dihydroxybenzoic acid …
2-Tridecanoyloxy-Pentadecanoic Acid
Experimental
Matched Name: … 2-Tridecanoyloxy-Pentadecanoic Acid …
Matched Iupac: … (3S)-3-(tridecanoyloxy)pentadecanoic acid …
Matched Iupac: … (3S)-3-(tridecanoyloxy)pentadecanoic acid …
Displaying drugs 1801 - 1825 of 2972 in total