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Displaying drugs 1801 - 1825 of 14984 in total

Eladocagene exuparvovec

Eladocagene exuparvovec is a recombinant adeno-associated virus-2 (AAV2)-based gene therapy that expresses human aromatic L-amino acid decarboxylase (AADC), and it is used to treat AADC deficiency, a fatal and rare genetic disorder that causes severe disability in pediatric patients.[L43642,L43672] Patients with AADC have mutations in the dopa decarboxylase (DDC) gene...
Approved
Investigational
Matched Description: … recombinant adeno-associated virus-2 (AAV2)-based gene therapy that expresses human aromatic L-amino acid ... decarboxylase (AADC), and it is used to treat AADC deficiency, a fatal and rare genetic disorder that ... neurotransmitter production, decrease neurotransmitter catabolism via monoamine oxidase (MAO) inhibition and …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Pentagastrin

A synthetic pentapeptide that mimics the actions of endogenous gastrin when given parenterally. It works by stimulating the secretion of gastric acid, pepsin, and intrinsic factor. It has also been used as a diagnostic aid.
Approved
Matched Iupac: … yl)propanamido]-4-(methylsulfanyl)butanamido]-3-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}propanoic acid …
Matched Description: … It works by stimulating the secretion of gastric acid, pepsin, and intrinsic factor. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Sebelipase alfa

The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption secondary...
Approved
Investigational
Matched Description: … The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism ... It was first approved by both the FDA and EMA in 2015 and is marketed under the brand name Kanuma (Alexion ... of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Olipudase alfa

Olipudase alfa is recombinant human acid sphingomyelinase. It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease. ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency...
Approved
Investigational
Matched Description: … [A251590] It is the first and only enzyme replacement therapy in the world for the treatment of Acid ... Olipudase alfa is recombinant human acid sphingomyelinase. ... a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency in acid …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Cetrimonium

Cetrimonium is a quaternary ammonium cation whose salts are used as antiseptics.
Approved
Matched Mixtures name: … Dermoplex Bite and Sting Cream ... NW BENZALKONIUM AND CETRIMIDE CREAM …
Matched Categories: … Antiseptics and Disinfectants …

Fluoxymesterone

An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Approved
Illicit
Matched Description: … anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Fluocinonide

A topical glucocorticoid used in the treatment of eczema.
Approved
Investigational
Matched Mixtures name: … Fluocinonide 0.05% / Hyaluronic Acid Sodium Salt 0.5% / Niacinamide 4% …
Matched Categories: … fluocinonide and antibiotics ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Inosine pranobex

Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.
Approved
Matched Iupac: … tris((2R)-1-(dimethylamino)propan-2-ol); tris(4-acetamidobenzoic acid); 9-[(2R,3R,4S,5R)-3,4-dihydroxy …
Matched Description: … and dimethylaminoisopropanol used as an antiviral drug. ... Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Cantharidin

Cantharidin is a naturally occurring odorless, colorless fatty substance of the terpenoid class that is produced as an oral fluid in the alimentary canal of the male blister beetle.[A32891, A32892] For its natural purpose, the male blister beetle secretes and presents the cantharidin to a female beetle as a copulatory...
Approved
Investigational
Matched Description: … genitourinary tracts, along with electrolyte and renal function disturbance in humans and animals [A32891 ... [A32891, A32892] For its natural purpose, the male blister beetle secretes and presents the cantharidin ... effectiveness at treating topical skin conditions like warts than other commonly available vesicant and …
Matched Mixtures name: … Cantharidin 1% / Podophyllum Resin 5% / Salicylic Acid 30% …

Podophyllin

Podophyllin is a resin extracted from the roots of Podophyllum peltatum (American mandrake) and Podophyllum emodi, which contains numerous compounds, amongst which is podophyllin (as well as the drug podophyllotoxin). Podophyllin is the principal active component. Podophyllin arrests mitosis in metaphase.
Approved
Matched Iupac: … 7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-2H,5H,6H,7H,8H-naphtho[2,3-d][1,3]dioxole-6-carboxylic acid …
Matched Description: … Podophyllin is a resin extracted from the roots of _Podophyllum peltatum_ (American mandrake) and _Podophyllum …
Matched Mixtures name: … Cantharidin 1% / Podophyllum Resin 5% / Salicylic Acid 30% …
Matched Categories: … Skin and Mucous Membrane Agents …

Pegloticase

Pegloticase is a porcine recombinant PEGylated uricase indicated for the treatment of chronic gout in adult patients that do not respond to other types of therapies. Pegloticase has a similar activity to rasburicase, an enzyme that metabolizes uric acid to allantoin. In gout patients treated with pegloticase, the conversion of...
Approved
Investigational
Matched Description: … uric acid concentrations. ... of pegloticase and methotrexate. ... In gout patients treated with pegloticase, the conversion of uric acid to allantoin leads to lower plasma …
Matched Categories: … Enzymes and Coenzymes ... Uric Acid-specific Enzyme …

Coagulation factor X human

Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and children (aged 12 years and above) with hereditary Factor X deficiency. However its use is limited in the perioperative setting for the management of bleeding in major surgery in patients with moderate and severe...
Approved
Investigational
Matched Description: … children (aged 12 years and above) with hereditary Factor X deficiency. ... Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and ... the perioperative setting for the management of bleeding in major surgery in patients with moderate and …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …

Pregnenolone

A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.
Approved
Experimental
Matched Description: … A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. ... Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Fluocinolone acetonide

Fluocinolone acetonide, with the formula 6-alpha, 9-alpha-difluoro-16-alpha, 17 alpha-acetonide, is a corticosteroid that presents a high lipophilicity. It has been used extensively in dermatological preparations and it has also been investigated thoroughly for its use in implantable corticosteroid devices. This type of device containing fluocinolone acetonide was developed by Taro...
Approved
Investigational
Vet approved
Matched Description: … [T357] It has been used extensively in dermatological preparations and it has also been investigated ... [T358] This type of device containing fluocinolone acetonide was developed by Taro Pharmaceuticals and …
Matched Mixtures name: … Ciprofloxacin and Fluocinolone Acetonide ... Ciprofloxacin and Fluocinolone Acetonide …
Matched Categories: … fluocinolone acetonide and antiseptics ... fluocinolone acetonide and antibiotics ... fluocinolone acetonide and antiinfectives ... fluocinolone acetonide and antiinfectives ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Equus caballus skin

Equus caballus skin allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Horse Hair and Dander …

Oryctolagus cuniculus skin

Oryctolagus cuniculus skin or pelt is used in allergenic testing.
Approved
Matched Mixtures name: … Rabbit Hair and Epithelia …

Pralidoxime

Pralidoxime is an antidote to organophosphate pesticides and chemicals. Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme. If given within 24 hours,after organophosphate exposure, pralidoxime reactivates the enzyme cholinesterase by cleaving the phosphate-ester bond formed between the organophosphate and acetylcholinesterase.
Approved
Vet approved
Matched Description: … Pralidoxime is an antidote to organophosphate pesticides and chemicals. ... reactivates the enzyme cholinesterase by cleaving the phosphate-ester bond formed between the organophosphate and …
Matched Mixtures name: … ATNAA atropine and pralidoxime chloride Auto-Injector …
Matched Categories: … pralidoxime and atropine …

Bromodiphenhydramine

Bromodiphenhydramine is an ethanolamine antihistamine with antimicrobial property. Bromodiphenhydramine is used in the control of cutaneous allergies. Ethanolamine antihistamines produce marked sedation in most patients.
Approved
Matched Mixtures name: … Diphenhydramine HCI and Zinc Acetate …

Canis lupus familiaris skin

Canis lupus familiaris skin allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Dog Hair and Epithelia …

Human adenovirus e serotype 4 strain cl-68578 antigen

Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine.
Approved
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …

Adenovirus type 7 vaccine live

Approved
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …

Apis mellifera venom

Apis mellifera venom is an extract of Apis mellifera venom. Apis mellifera venom is used in allergenic testing.
Approved
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Bee Venom Wart And Tags Removal Treatment …
Matched Categories: … Bee and Wasp Venom …

Diethylamino hydroxybenzoyl hexyl benzoate

Diethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage, diethylamino hydroxybenzoyl hexyl benzoate is an oil-soluble UV filter that may be incorporated in the oil phase of...
Approved
Matched Description: … U.S., South America, Mexico, Japan and Taiwan. ... Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic ... Diethylamino hydroxybenzoyl hexyl benzoate was approved in Europe in 2005, and is also marketed in the …
Matched Mixtures name: … Kiehls Activated Sun Protector Sunscreen SPF 50 For Face and Body For All Skin Types ... Kiehls Activated Sun Protector Sunscreen SPF 30 For Face and Body For All Skin Types …

Proparacaine

Proparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
Approved
Vet approved
Matched Mixtures name: … Fluorescein Sodium and Proparacaine Hydrochloride …

Procaterol

A long-acting beta-2-adrenergic receptor agonist. It is a potent bronchodilator that may be administered orally or by aerosol inhalation.
Approved
Investigational
Displaying drugs 1801 - 1825 of 14984 in total