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Displaying drugs 1926 - 1950 of 1952 in total

Hydromorphone

Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Description: … the absence of a double bond between the carbon 7 and 8. ... hydrochloride was developed by Fresenius Kabi USA and FDA approved in 1984. ... hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and …
Matched Categories: … hydromorphone and naloxone ... hydromorphone and antispasmodics ... Semi-synthetic Opioids …
Matched Products: … Hydromorphone Hp Forte Injection ... Hydromorphone Hydrochloride Injection Hp Forte …

Levothyroxine

Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Description: … produce sufficient quantities of the thyroid hormones T4 (tetraiodothyronine or thyroxine) and ... hypothyroidism begin to develop such as fatigue, increased heart rate, depression[A179620], dry skin and ... hair, muscle cramps, constipation, weight gain, memory impairment, and poor tolerance to cold temperatures …
Matched Mixtures name: … Combithyrex forte - Tabletten ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... levothyroxine sodium and iodine compounds …
Matched Products: … Levothyroxine Sodium for Injection ... LEVOTHYROXINE SODIUM FOR INJECTION 500 mcg/vial …

Ketoconazole

Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Iupac: … 1-[4-(4-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin …
Matched Description: … [FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol ... [A181802,T116] Ketoconazole was first approved in an oral formulation for systemic use by the FDA in ... Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal …
Matched Categories: … Steroid Synthesis Inhibitors ... Sex Hormones and Insulins ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … FAZOL FORTE SHAMPOO ... FAZOL® FORTE HERBAL SHAMPOO …

Epinephrine

Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been...
Approved
Vet approved
Matched Description: … Epinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal ... , and subcutaneous injection. ... Many new products/biosimilars and dosage routes have been approved under various names over the last …
Matched Mixtures name: … Ultacan Forte ... Citanest Forte ... Lignospan Forte …
Matched Categories: … epinephrine and other drugs for obstructive airway diseases ... Phenols ... Adrenergic and Dopaminergic Agents ... Alpha-and Beta-adrenergic Agonists ... Antiglaucoma Preparations and Miotics …
Matched Products: … ARTINIBSA 4% WITH EPINEPHRINE SOLUTION FOR INJECTION 1:100000 …

Mannitol

Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a...
Approved
Investigational
Matched Description: … pulmonary symptoms associated with cystic fibrosis in adult patients and is currently marketed for this ... or sugar alcohol, in fruits and vegetables. ... As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure …
Matched Mixtures name: … INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion) ... TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND ... (Saving Platelets) with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) and …
Matched Categories: … Drugs for Constipation ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Cough and Cold Preparations …
Matched Products: … Braun Mannitol 20% Solution for Infusion …

Verapamil

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and ... angina,[L8791] and was the first calcium channel antagonist to be introduced into therapy in the early ... of the non-dihydropyridine class of calcium channel blockers, which includes drugs like [diltiazem] and …
Matched Mixtures name: … TARKA FORTE 240/4 FILM TABLET, 28 ADET ... VERAPIN FORTE 240MG/4MG FILM TABLET,28 ADET ... Trandolapril and Verapamil Hydrochloride …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Verapamil and analogues ... trandolapril and verapamil ... Antihypertensive Agents Indicated for Hypertension …
Matched Products: … Isocor 2.5 mg/mL solution for injection or infusion …

Butylscopolamine

Butylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent. It is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic activity in the digestive system. It is also effective at preventing bladder spasms. It is not a pain medication in the normal sense, since it...
Approved
Investigational
Vet approved
Matched Description: … It is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic ... the normal sense, since it does not directly affect pain, but rather works to prevent painful cramps and …
Matched Mixtures name: … COLFEM FORTE TABLETAS ... LABINPINA FORTE 10/500 MG TABLETAS CUBIERTAS ( HIOSCINA N- BUTILBROMURO + ACETAMINOFEN ) …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... butylscopolamine and analgesics ... Drugs for Functional Gastrointestinal Disorders …
Matched Products: … Fucon Solution for Injection 20mg/ml …

Ambroxol

Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the...
Approved
Investigational
Matched Description: … It stimulates synthesis and release of surfactant by type II pneumocytes. ... in providing protection against infection and irritating agents. ... The substance is a mucoactive drug with several properties including secretolytic and secretomotoric …
Matched Categories: … Cough and Cold Preparations ... clenbuterol and ambroxol ... Adrenergics for Systemic Use ... Drugs for Obstructive Airway Diseases …
Matched Products: … MUCERA FORTE ... SILOPECT FORTE …

Baclofen

Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Description: … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence ... used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … OREN FORTE TABLETAS …

Morphine

Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Description: … [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk ... strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and ... [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids …
Matched Categories: … morphine and antispasmodics …
Matched Products: … Morphine Forte ... Morphine Extra-forte …

Ursodeoxycholic acid

Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational
Matched Description: … [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary ... [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by ... [A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional …
Matched Categories: … Alimentary Tract and Metabolism ... Bile acids and derivatives ... Bile Acids and Salts ... Bile and Liver Therapy ... Cholagogues and Choleretics …
Matched Products: … Urso Forte …

Allopurinol

Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals . Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Description: … This disease has been well-documented in historical medical records and appears in the biographies of ... enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and ... It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [ …
Matched Products: … MEDIURIC FORTE …

Estradiol

Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams.[L11485,L11488,L11491,...
Approved
Investigational
Vet approved
Matched Description: … [DB00977] (EE) is a synthetic form of estradiol commonly used as the estrogenic component of most combination ... , sprays, gels, and creams. ... reduced estrogen, such as vulvovaginal atrophy and hot flashes. …
Matched Mixtures name: … Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate …
Matched Categories: … Hormonal Contraceptives for Systemic Use ... Androgens and Estrogens ... Antiandrogens and Estrogens ... Pituitary and Hypothalamic Hormones and Analogues ... etynodiol and estrogen …
Matched Products: … CLIMARA FORTE 7.8 MG/25 CM2 TRANSDERMAL FLASTER, 4 ADET …

Prednisolone

Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Description: … , anti-neoplastic, and vasoconstrictive effects. ... Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Corticosteroids for Systemic Use ... Corticosteroids for Systemic Use, Plain ... Corticosteroids for Local Oral Treatment ... Alimentary Tract and Metabolism …
Matched Products: … NORSOL % 1 FORTE GÖZ KULAK DAMLASI, ÇÖZELTİ, 5 ML …

Telmisartan

Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Mixtures name: … CORDIAX D FORTE COMPRIMIDOS ... SYNTHESIS CORDIAX D ... SYNTHESIS CORDIAX® D COMPRIMIDOS …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension ... Angiotensin II receptor blockers (ARBs) and diuretics ... telmisartan and amlodipine ... telmisartan and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Matched Products: … Semintra 4mg/ml Oral Solution for Cats …

Terbinafine

Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues ... Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. ... [A1279] Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Systemic Use ... Antifungals for Dermatological Use …
Matched Products: … Lamisil AT for Jock Itch …

Cyanocobalamin

Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched Description: … This vitamin is produced naturally by bacteria [A175276], and is necessary for DNA synthesis and cellular ... Vitamin B12 has many forms, including the cyano-, methyl-, deoxyadenosyl- and hydroxy-cobalamin forms ... The _cyano_ form, is the most widely used form in supplements and prescription drugs [A175255], [FDA …
Matched Mixtures name: … Multivitamins and Minerals for Men ... Multivitamins and Minerals for Women ... Luna Vitamin and Mineral Bar for Women …
Matched Categories: … Blood and Blood Forming Organs ... Diet, Food, and Nutrition ... Vitamin B12 and Folic Acid ... iron, vitamin B12 and folic acid …
Matched Products: … VITAMIN B12 FORTE HEV INJ …

Tamsulosin

Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.[Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy.[Label] Antagonism of these receptors leads to relaxation of smooth muscle in...
Approved
Investigational
Matched Description: … [Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. ... Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect ... in the prostate and bladder, where these receptors are most common. …
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones ... tamsulosin and tadalafil ... tamsulosin and dutasteride ... tamsulosin and solifenacin ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … TAMSIN FORTE, Tamsulosin Hydrochloride 0.4mg Prolonged Release Tablets …

Losartan

Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Description: … available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and ... [L7423,L7426] Patients taking losartan should have their renal function and potassium levels monitored ... [L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated …
Matched Mixtures name: … HYZAAR® FORTE 100 / 25MG ... TENSARTAN HCT FORTE 100/25 ... HYZAAR FORTE TABLET 100/25 mg …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... losartan and diuretics ... losartan and amlodipine ... Antihypertensive Agents Indicated for Hypertension …
Matched Products: … HILOS FORT 100 MG FILM TABLET, 28 ADET …

Risperidone

Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). Schizophrenia and...
Approved
Investigational
Matched Description: … mental health conditions including schizophrenia and bipolar disorder. ... D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways and mesocortical ... Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and …
Matched Products: … RISPERDAL CONSTA FOR INJECTION 25 mg/vial ... RISPERDAL CONSTA FOR INJECTION 37.5 mg/vial …

Bromhexine

Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as...
Approved
Matched Description: … [A233240] Recently, bromhexine and its metabolite [ambroxol] have garnered interest for the potential ... and reducing cough. ... It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … DISOL FORTE ELIXIR 8 MG/5ML …

Buprenorphine

Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Description: … duration of action and relief from pain or withdrawal symptoms for upwards of 24-36 hours. ... used for the treatment of severe pain. ... Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist …
Matched Mixtures name: … Buprenorphine HCl and Naloxone HCl ... Buprenorphine and Naloxone ... Buprenorphine and Naloxone …
Matched Products: … TEMGESIC FORTE SUBLI 0.4MG …

Sildenafil

In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Description: … effective treatment for erectile dysfunction and since its formal approval for medical use in the public ... it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth …
Matched Products: … Sildenafil for Oral Suspension …

Venlafaxine

Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and...
Approved
Matched Description: … , and panic disorder in Canada for many years. ... headaches,[A413,A177229] for reduction of vasomotor symptoms associated with menopause,[A177238] and ... Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Antidepressive Agents Indicated for Depression …
Matched Products: … VENLEX FORTE XR CAPSULES 150MG …

Valsartan

Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Description: … and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of ... Valsartan is commonly used for the management of hypertension, heart failure, and Type 2 Diabetes-associated ... [A174124,A173869] Valsartan was initially approved in 1996 in Europe for the treatment of hypertension …
Matched Mixtures name: … CODIOVAN FORTE 160/25MG ... COTAREG FORTE 160MG/25MG ... CODIOVAN FORTE 160MG/25MG …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension ... Angiotensin II Antagonists and Diuretics ... Angiotensin II Antagonists and Calcium Channel Blockers ... valsartan and nebivolol ... valsartan and diuretics …
Matched Products: … DIOVAN 320MG FORTE FILMTAB …
Displaying drugs 1926 - 1950 of 1952 in total