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Displaying drugs 1926 - 1950 of 15179 in total

Meningococcal polysaccharide vaccine group Y

Meningococcal group Y polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup Y. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup Y.
Approved
Experimental
Investigational
Matched Description: … *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia ... Meningococcal group Y polysaccharide is group-specific polysaccharide antigens extracted and purified …
Matched Mixtures name: … Menveo Powder and Solution for Solution for Injection ... NIMENRIX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Nimenrix Powder and Solvent for Solution for Injection …

Thrombin alfa

Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human thrombin. Thrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically...
Approved
Matched Description: … Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human ... that is proteolytically converted to a two-chain active form (using a protein derived from snakes) and ... The purification process includes solvent-detergent treatment and nano-filtration steps dedicated to …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …

Prednisolone

Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Description: … glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Sex Hormones and Insulins ... prednisolone and mydriatics ... abiraterone and prednisolone …

Ouabain

A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase.
Approved
Matched Description: … gratus and other plants of the Apocynaceae; used like digitalis. ... A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus …

Sacubitril

Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. It was approved by the FDA after being given the status of priority review for on July 7, 2015....
Approved
Matched Iupac: … 3-{[(2S,4R)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoic acid …
Matched Description: … such as angiotensin I and II, endothelin-1 and peptide amyloid beta-protein. ... ANP and BNP are released under atrial and ventricle stress, which activate downstream receptors leading ... to vasodilation, natriuresis and diuresis. …
Matched Categories: … valsartan and sacubitril ... Amino Acids, Peptides, and Proteins …

Mannitol

Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a...
Approved
Investigational
Matched Description: … As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure ... or sugar alcohol, in fruits and vegetables. ... cerebrospinal fluid, into interstitial fluid and plasma. …
Matched Mixtures name: … INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion) ... TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND ... (Saving Platelets) with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) and …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Cough and Cold Preparations ... Blood Substitutes and Perfusion Solutions …

Vancomycin

Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of...
Approved
Matched Iupac: … }.0^{34,39}]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid …
Matched Description: … kidneys and the inner ear. ... It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to ... liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Cavia porcellus dander

Cavia porcellus dander allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Animal Allergens, Guinea Pig Hair and Dander ... Animal Allergens, Guinea Pig Hair and Dander …

Adenine

A purine base and a fundamental unit of adenine nucleotides.
Approved
Nutraceutical
Matched Description: … A purine base and a fundamental unit of adenine nucleotides. …
Matched Mixtures name: … TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND ... (Saving Platelets) with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) and ... Removing Platelets) with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND …

Tiotropium

Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma.[A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.[A180163,L7084,L7087,L7090,L7093] Tiotropium is more specific for the subset of muscarinic receptors commonly found in the...
Approved
Matched Description: … antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and ... Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and …
Matched Categories: … olodaterol and tiotropium bromide ... formoterol and tiotropium bromide …

Oat

Oat allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Aveeno Moisturizing Shower and Bath Oil ... Aveeno Moisturizing Shower and Bath Oil …

Palbociclib

Palbociclib is a piperazine pyridopyrimidine that acts in the cell cycle machinery. It is a second generation cyclin-dependent kinase inhibitor selected from a group of pyridopyrimidine compounds due to its favorable physical and pharmaceutical properties. Palbociclib was developed by Pfizer Inc after the discovery that identified the cyclin-dependent kinases as...
Approved
Investigational
Matched Description: … electronic health records demonstrating safety and clinical efficacy. ... inhibitor[A176798] selected from a group of pyridopyrimidine compounds due to its favorable physical and ... on March 2015 for the treatment of HR-positive, HER2-negative advanced or metastatic breast cancer and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Stannous chloride

Stannous chloride is used as a source of tin in radiopharmaceutical kits. Tin reduces technetium-99m, the active radiological agent, allowing it to form a complex with phosphate-containing moeities . These complexes localize primarily in bone (40-50%) and infracted myocardium (0.01-0.02%/g of tissue) allowing for imaging of areas of altered osteogenesis...
Approved
Matched Description: … These complexes localize primarily in bone (40-50%) and infracted myocardium (0.01-0.02%/g of tissue) …
Matched Mixtures name: … Multivitamins and Minerals Tablets ... Spectrum Performa Multivitamins and Minerals Tablets …

Imdevimab

Imdevimab is a monoclonal antibody combined with casirivimab in Regeneron's antibody cocktail known as REGEN-COV2 for the treatment of COVID-19. This drug is a combination of antibodies derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. These antibodies have been formulated to...
Approved
Experimental
Matched Description: … [L39130,L39135] Full safety and efficacy data on imdevimab are not yet available, and further evaluation ... Casirivimab and imdevimab are investigational recombinant human IgG1 monoclonal antibodies that, at this ... authorized emergency approval of REGN-COV2 to treat mild to moderate COVID-19 in patients aged 12 years and …
Matched Mixtures name: … Casirivimab and Imdevimab ... Casirivimab and Imdevimab …
Matched Categories: … casirivimab and imdevimab ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …

Lolium perenne pollen

Lolium perenne pollen is the pollen of the Lolium perenne plant. Lolium perenne pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Standardized and Non-Standardized Inland Grasses ... Mixture of Standardized and Non-Standardized Coastal Grasses ... Mixture of Twenty-Two Standardized and Non-Standardized Grasses …

Arrhenatherum elatius pollen

Arrhenatherum elatius pollen is the pollen of the Arrhenatherum elatius plant. Arrhenatherum elatius pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Standardized and Non-Standardized Coastal Grasses ... Mixture of Twenty-Two Standardized and Non-Standardized Grasses …

Cyd dengue virus serotype 3 live (attenuated) antigen

Approved
Matched Mixtures name: … DENGVAXIA MD, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION ... DENGVAXIA, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION …

Bromus inermis pollen

Bromus inermis pollen is the pollen of the Bromus inermis plant. Bromus inermis pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Standardized and Non-Standardized Inland Grasses ... Mixture of Twenty-Two Standardized and Non-Standardized Grasses …

Epinastine

Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Description: … H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory ... cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and …
Matched Categories: … Acid Reducers ... Decongestants and Antiallergics …

Telaprevir

Telaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Withdrawn
Matched Description: … Subtitutions at amino acid positions 155, 156, or 168 are known to confer resistance. ... into mature proteins like NS4A, NS4B, NS5A and NS5B. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Sipuleucel-T

Sipuleucel-T is a personalized, autologous, cellular immunotherapy. Sipuleucel-T is a therapeutic cancer vaccine for prostate cancer. Sipuleucel-T selectively targets the prostate-specific antigen (PSA) known as prostatic acid phosphatase (PAP) that is expressed in around 95% of prostate cancers. It must be prepared specifically for each patient. In metastatic prostate cancer,...
Approved
Investigational
Matched Description: … Sipuleucel-T selectively targets the prostate-specific antigen (PSA) known as prostatic acid phosphatase ... Food and Drug Administration (FDA) on April 29, 2010, to treat asymptomatic or minimally symptomatic …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Piperonyl butoxide

Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is used for the treatment of head, pubic (crab), and body lice. Piperonyl butoxide is a synergist. It has no pesticidal activity of its own, but acts to increase the activity of pesticides such as...
Approved
Vet approved
Matched Description: … It is used for the treatment of head, pubic (crab), and body lice. ... its own, but acts to increase the activity of pesticides such as carbamates, pyrethrins, pyrethroids, and …
Matched Mixtures name: … Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer ... Weeks and Leo Complete Lice Treatment …

Conjugated estrogens

The conjugated estrogens are noncrystalline mixtures of purified female sex hormones obtained either by its isolation from the urine of pregnant mares or by synthetic generation from vegetal material. Both of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble.[L5605,...
Approved
Matched Description: … 17-beta-dihydroequilenin sulfate, 2% of 17-alpha-estradiolsulfate and 3% of 17-beta-estradiolsulfate ... equilin sulfate, 15% of 17-alpha-dehydroequilenin sulfate, 3% of equilenin sulfate, 5% of 17-alpha and ... However, until 1986 official clinical trials were performed and this product was determined to be effective …
Matched Mixtures name: … Esterified Estrogens and Methyltestosterone ... Esterified Estrogens and Methyltestosterone …
Matched Categories: … Genito Urinary System and Sex Hormones ... conjugated estrogens and bazedoxifene ... Natural and Semisynthetic Estrogens, Plain ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Hydroflumethiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p822)
Approved
Investigational
Withdrawn
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … hydroflumethiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Abarelix

Synthetic decapeptide antagonist to gonadotropin releasing hormone (GnRH). It is marketed by Praecis Pharmaceuticals as Plenaxis. Praecis announced in June 2006 that it was voluntarily withdrawing the drug from the market.
Approved
Investigational
Withdrawn
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormone Antagonists and Related Agents ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 1926 - 1950 of 15179 in total