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Displaying drugs 176 - 200 of 375 in total
Acemetacin
Acemetacin is a carboxymethyl ester of indometacin. It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity is thought to be mainly through its active metabolite indomethacin. In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin. It was developed by...
Approved
Investigational
Matched Iupac: … 2-({2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl}oxy)acetic acid …
Matched Description: … Merck and Company in Germany as an attempt to provide a safer drug but other than the amelioration on ... the gastrointestinal effects, the metabolism of acetamicin led to the formation of indomethacin and …
Matched Categories: … Non COX-2 selective NSAIDS ... Heterocyclic Compounds, 2-Ring ... Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Description: … Merck and Company in Germany as an attempt to provide a safer drug but other than the amelioration on ... the gastrointestinal effects, the metabolism of acetamicin led to the formation of indomethacin and …
Matched Categories: … Non COX-2 selective NSAIDS ... Heterocyclic Compounds, 2-Ring ... Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Lornoxicam
Lornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. Lornoxicam is approved for use in Japan.
Approved
Investigational
Matched Iupac: … 6-chloro-4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1λ⁶-thieno[2,3-e][1,2]thiazine-3-carboxamide …
Matched Description: … new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and …
Matched Categories: … Non COX-2 selective NSAIDS ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … XEFO 8 MG 2 ML FLAKON, 1 ADET …
Matched Description: … new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and …
Matched Categories: … Non COX-2 selective NSAIDS ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … XEFO 8 MG 2 ML FLAKON, 1 ADET …
Amorolfine
Amorolfine or amorolfin, is a morpholine antifungal drug that inhibits the fungal enzymes D14 reductase and D7-D8 isomerase. This inhibition affects fungal sterol synthesis pathways, depleting ergosterol and causing ignosterol to accumulate in the fungal cytoplasmic cell membranes. Amorolfine is marketed as Curanail, Loceryl, Locetar, and Odenil. It is available...
Approved
Investigational
Matched Iupac: … (2R,6S)-2,6-dimethyl-4-(2-{[4-(2-methylbutan-2-yl)phenyl]methyl}propyl)morpholine …
Matched Description: … It is available in the form of a 5% amorolfine nail lacquer used to treat onychomycosis (fungal infection ... of the toe- and fingernails). ... Amorolfine is marketed as Curanail, Loceryl, Locetar, and Odenil. …
Matched Description: … It is available in the form of a 5% amorolfine nail lacquer used to treat onychomycosis (fungal infection ... of the toe- and fingernails). ... Amorolfine is marketed as Curanail, Loceryl, Locetar, and Odenil. …
Metyrapone
An inhibitor of the enzyme steroid 11-beta-monooxygenase. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.
Approved
Investigational
Matched Iupac: … 2-methyl-1,2-bis(pyridin-3-yl)propan-1-one …
Lutetium Lu 177 dotatate
A 177Lu-labeled somatostatin analog peptide, Lutetium Lu 177 dotatate belongs to an emerging form of treatments called Peptide Receptor Radionuclide Therapy (PRRT), which involves targeting tumours with molecules carrying radioactive particles that bind to specific receptors expressed by the tumour. Lutetium Lu 177 dotatate may also be referred to as...
Approved
Investigational
Matched Iupac: … 2-hydroxypropyl]carbamoyl}-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl ... }methyl)-7,10-bis(carboxylatomethyl)-1,4,7,10-tetraazacyclododecan-1-yl]acetate ... (177Lu)lutetium(3+) 2-[4-({[(1R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(1S,2R)-1-carboxy- ... ]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]carbamoyl}-2-phenylethyl]carbamoyl …
Matched Description: … A 177Lu-labeled somatostatin analog peptide, Lutetium Lu 177 dotatate belongs to an emerging form of ... Targeting pancreas and other parts of the gastrointestinal tract such as the intestines and colon, neuroendocrine ... tumors may commonly metastasize to metastasize to the mesentery, peritoneum, and liver [A31697]. …
Matched Categories: … Indicators and Reagents ... Somatostatin and Analogues ... Amino Acids, Peptides, and Proteins …
Matched Description: … A 177Lu-labeled somatostatin analog peptide, Lutetium Lu 177 dotatate belongs to an emerging form of ... Targeting pancreas and other parts of the gastrointestinal tract such as the intestines and colon, neuroendocrine ... tumors may commonly metastasize to metastasize to the mesentery, peritoneum, and liver [A31697]. …
Matched Categories: … Indicators and Reagents ... Somatostatin and Analogues ... Amino Acids, Peptides, and Proteins …
Rizatriptan
Rizatriptan is a second-generation triptan and a selective 5-HT1B and 5-HT1D receptor agonist. Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film formulations.
Approved
Matched Synonyms: … N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine …
Matched Iupac: … dimethyl(2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Description: … Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT1B and 5-HT1D receptor ... [L46018] Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Iupac: … dimethyl(2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Description: … Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT1B and 5-HT1D receptor ... [L46018] Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Ritonavir
Ritonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. Although it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimens with low-dose ritonavir and other protease inhibitors. It is now more commonly used as a...
Approved
Investigational
Matched Iupac: … (1,3-thiazol-5-yl)methyl N-[(2S,3S,5S)-3-hydroxy-5-[(2S)-3-methyl-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol ... -4-yl]methyl})carbamoyl]amino}butanamido]-1,6-diphenylhexan-2-yl]carbamate …
Matched Description: … drugs to treat coronavirus disease 2019 (COVID-19) in patients at risk for progressing into a severe form ... While ritonavir is not an active antiviral agent against hepatitis C virus (HCV) infection, it is added ... indicated in combination with Ribavirin for the treatment of patients with genotype 4 chronic hepatitis C …
Matched Mixtures name: … Lopinavir and Ritonavir ... Lopinavir and ritonavir ... Lopinavir and ritonavir …
Matched Categories: … Treatments for Hepatitis C ... lopinavir and ritonavir ... darunavir and ritonavir ... atazanavir and ritonavir ... nirmatrelvir and ritonavir …
Matched Description: … drugs to treat coronavirus disease 2019 (COVID-19) in patients at risk for progressing into a severe form ... While ritonavir is not an active antiviral agent against hepatitis C virus (HCV) infection, it is added ... indicated in combination with Ribavirin for the treatment of patients with genotype 4 chronic hepatitis C …
Matched Mixtures name: … Lopinavir and Ritonavir ... Lopinavir and ritonavir ... Lopinavir and ritonavir …
Matched Categories: … Treatments for Hepatitis C ... lopinavir and ritonavir ... darunavir and ritonavir ... atazanavir and ritonavir ... nirmatrelvir and ritonavir …
Sucralfate
Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia . It is considered a cytoprotective agent, protecting cells in...
Approved
Matched Iupac: … ]oxolan-2-yl]oxy}-4,5-bis({[(dihydroxyalumanyl)oxy]sulfonyl}oxy)-2-[({[(dihydroxyalumanyl)oxy]sulfonyl ... }oxy)methyl]oxan-3-yl]oxy}sulfonyl)oxy]alumanediol alumanetriol hydrate ... 4R,5R)-3,4-bis({[(dihydroxyalumanyl)oxy]sulfonyl}oxy)-2,5-bis[({[(dihydroxyalumanyl)oxy]sulfonyl}oxy)methyl …
Matched Description: … It was approved by the FDA 1982 in tablet form, and in 1994 for the suspension form [L6073, L6076]. ... It is sold under many brands and is available in both tablet and suspension forms. ... Sucralfate has been shown to be a well-tolerated and safe drug. …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Description: … It was approved by the FDA 1982 in tablet form, and in 1994 for the suspension form [L6073, L6076]. ... It is sold under many brands and is available in both tablet and suspension forms. ... Sucralfate has been shown to be a well-tolerated and safe drug. …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Pibrentasvir
Pibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets the the viral RNA replication and viron assembly. In combination with DB13879, pibrentastiv is a useful therapy for patients who experienced therapeutic failure from other NS5A inhibitors. In cell cultures, the emergence of amino...
Approved
Investigational
Matched Iupac: … methyl N-[(2S,3R)-1-[(2S)-2-{5-[(2R,5R)-1-{3,5-difluoro-4-[4-(4-fluorophenyl)piperidin-1-yl]phenyl}-5 ... -{6-fluoro-2-[(2S)-1-[(2S,3R)-3-methoxy-2-[(methoxycarbonyl)amino]butanoyl]pyrrolidin-2-yl]-1H-1,3-benzodiazol ... -5-yl}pyrrolidin-2-yl]-6-fluoro-1H-1,3-benzodiazol-2-yl}pyrrolidin-1-yl]-3-methoxy-1-oxobutan-2-yl]carbamate …
Matched Description: … Pibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets ... Hepatitis C viral infection often leads to decreased liver function and subsequent liver failure, causing ... fixed-dose combination therapy was FDA-approved in August 2017 to treat adults with chronic hepatitis C …
Matched Categories: … glecaprevir and pibrentasvir ... Heterocyclic Compounds, 2-Ring ... Treatments for Hepatitis C ... Hepatitis C Virus NS5A Inhibitor …
Matched Description: … Pibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets ... Hepatitis C viral infection often leads to decreased liver function and subsequent liver failure, causing ... fixed-dose combination therapy was FDA-approved in August 2017 to treat adults with chronic hepatitis C …
Matched Categories: … glecaprevir and pibrentasvir ... Heterocyclic Compounds, 2-Ring ... Treatments for Hepatitis C ... Hepatitis C Virus NS5A Inhibitor …
Letrozole
Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Approved
Investigational
Matched Iupac: … 4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl)methyl]benzonitrile …
Matched Description: … ], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. ... [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … ], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. ... [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Doxycycline
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and...
Approved
Investigational
Vet approved
Matched Iupac: … 6,11,12a-octahydrotetracene-2-carboxamide ... (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a, …
Matched Description: … It is also used to treat acne and malaria.[A251730] ... [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Description: … It is also used to treat acne and malaria.[A251730] ... [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Alpelisib
Alpelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potent antitumor activity. It works by selectively inhibiting class I PI3K p110α , which is the catalytic subunit of PI3K, a lipid kinase that plays a role in various biological processes, including proliferation, survival, differentiation, and metabolism. Alpelisib was designed to target...
Approved
Investigational
Matched Iupac: … (2S)-N1-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine …
Matched Description: … indicated for the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 ... Alpelisib is marketed under the trade name Piqray and is available as oral tablets. ... that plays a role in various biological processes, including proliferation, survival, differentiation, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … indicated for the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 ... Alpelisib is marketed under the trade name Piqray and is available as oral tablets. ... that plays a role in various biological processes, including proliferation, survival, differentiation, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Estradiol
Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams.[L11485,L11488,L11491,...
Approved
Investigational
Vet approved
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-1,7 …
Matched Description: … [DB00977] (EE) is a synthetic form of estradiol commonly used as the estrogenic component of most combination ... therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and ... forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and …
Matched Mixtures name: … Estradiol and Progesterone ... Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Androgens and Estrogens ... Antiandrogens and Estrogens ... etynodiol and estrogen ... dienogest and estrogen …
Matched Products: … VIPLEN 2 MG ... POSTMENOP 2 MG ... ESTROFEM TABLET 2 mg …
Matched Description: … [DB00977] (EE) is a synthetic form of estradiol commonly used as the estrogenic component of most combination ... therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and ... forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and …
Matched Mixtures name: … Estradiol and Progesterone ... Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Androgens and Estrogens ... Antiandrogens and Estrogens ... etynodiol and estrogen ... dienogest and estrogen …
Matched Products: … VIPLEN 2 MG ... POSTMENOP 2 MG ... ESTROFEM TABLET 2 mg …
Daclatasvir
Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. It is marketed under the name DAKLINZA and is contained in daily oral tablets as the hydrochloride salt form . Hepatitis C is an infectious liver disease...
Approved
Investigational
Matched Iupac: … methyl N-[(2S)-1-[(2S)-2-[5-(4'-{2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl]pyrrolidin ... -2-yl]-1H-imidazol-5-yl}-[1,1'-biphenyl]-4-yl)-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan- ... 2-yl]carbamate …
Matched Description: … form . ... Hepatitis C is an infectious liver disease caused by infection with Hepatitis C Virus (HCV). ... Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment …
Matched Categories: … Hepatitis C Virus NS5A Inhibitor ... Amino Acids, Peptides, and Proteins ... daclatasvir, asunaprevir and beclabuvir …
Matched Description: … form . ... Hepatitis C is an infectious liver disease caused by infection with Hepatitis C Virus (HCV). ... Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment …
Matched Categories: … Hepatitis C Virus NS5A Inhibitor ... Amino Acids, Peptides, and Proteins ... daclatasvir, asunaprevir and beclabuvir …
Levomenthol
Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Synonyms: … (1R-(1-α,2-β,5-α))-5-methyl-2-(1-methylethyl)cyclohexanol ... (1alpha,2beta,5alpha)-5-methyl-2(1-methylethyl)cyclohexanol ... (-)-Menthol …
Matched Iupac: … (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol …
Matched Description: … -)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration ... Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used ... Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils …
Matched Mixtures name: … Axpain Methyl Salicylate Gel ... Axpain Methyl Salicylate Cream ... JASIMENTH C PASTILLES …
Matched Categories: … Basic Lotions and Liniments ... Herbs and Natural Products ... Antipruritics and Local Anesthetics ... Other Cold and Cough Preparations …
Matched Products: … Obus Form Therapeutic Ice Gel ... Musle and Joint ... Performance and Recovery …
Matched Iupac: … (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol …
Matched Description: … -)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration ... Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used ... Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils …
Matched Mixtures name: … Axpain Methyl Salicylate Gel ... Axpain Methyl Salicylate Cream ... JASIMENTH C PASTILLES …
Matched Categories: … Basic Lotions and Liniments ... Herbs and Natural Products ... Antipruritics and Local Anesthetics ... Other Cold and Cough Preparations …
Matched Products: … Obus Form Therapeutic Ice Gel ... Musle and Joint ... Performance and Recovery …
Tiludronic acid
Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to etidronic acid and clodronic acid.[A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone....
Approved
Investigational
Vet approved
Matched Iupac: … {[(4-chlorophenyl)sulfanyl](phosphono)methyl}phosphonic acid …
Matched Description: … thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to [etidronic acid] and ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization …
Matched Description: … thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to [etidronic acid] and ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization …
Acyclovir
Acyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis.[L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. Acyclovir was granted FDA...
Approved
Matched Iupac: … 2-amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one …
Matched Description: … analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and ... L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and …
Matched Categories: … MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring ... Acyclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … AKLOVIR %5 KREM, 2 G ... ASIVIRAL %5 KREM, 2 GR ... ZOVIRAX %5 KREM, 2 G …
Matched Description: … analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and ... L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and …
Matched Categories: … MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring ... Acyclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … AKLOVIR %5 KREM, 2 G ... ASIVIRAL %5 KREM, 2 GR ... ZOVIRAX %5 KREM, 2 G …
Spironolactone
Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … [A178192] It promotes sodium and water excretion and potassium retention. ... It binds to mineralocorticoid receptors and functions as aldosterone antagonists. ... [L44602] Off-label uses of spironolactone include hirsutism, female pattern hair loss, and adult acne …
Matched Mixtures name: … Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% / Tretinoin 0.05% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% / Tretinoin 0.025% …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Mixtures name: … Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% / Tretinoin 0.05% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% / Tretinoin 0.025% …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Oxymorphone
An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia (From Martindale, The Extra Pharmacopoeia,...
Approved
Investigational
Vet approved
Matched Iupac: … (1S,5R,13R,17S)-10,17-dihydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Description: … An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough ... 2017, FDA requested Endo Pharmaceuticals to remove the medication from the market due to opioid misuse and …
Matched Description: … An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough ... 2017, FDA requested Endo Pharmaceuticals to remove the medication from the market due to opioid misuse and …
Telotristat ethyl
Telotristat ethyl is a prodrug of telotristat that was approved by the FDA in March 2017 as Xermelo. It was previously referred to as telotristat etiprate, the hippurate salt form; however, the FDA recommends the use of the name of the neutral form rather than that of the salt.[A252937, A252942]...
Approved
Investigational
Matched Iupac: … ethyl (2S)-2-amino-3-(4-{2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy …
Matched Description: … , and serotonin. ... FDA recommends the use of the name of the neutral form rather than that of the salt. ... [L43342] It was previously referred to as telotristat etiprate, the hippurate salt form; however, the …
Matched Description: … , and serotonin. ... FDA recommends the use of the name of the neutral form rather than that of the salt. ... [L43342] It was previously referred to as telotristat etiprate, the hippurate salt form; however, the …
Avacopan
Anti-neutrophil cytoplasmic (auto)antibody (ANCA)-associated vasculitis (AAV) is a rare (estimated incidence of 3 cases per 100,000 per year) form of "pauci-immune" systemic small-vessel vasculitis typified by the presence of ANCAs in the serum.[A240249, A240254, A227003] The full spectrum of AAV includes granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), eosinophilic granulomatosis...
Approved
Investigational
Matched Iupac: … (2R,3S)-2-[4-(cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl …
Matched Description: … (ANCA)-associated vasculitis (AAV) is a rare (estimated incidence of 3 cases per 100,000 per year) form ... [A240249, A240254] Despite complex pathophysiology, studies over the past ~2 decades have identified ... fragment C5a and its cognate C5aR receptor in AAV. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … (ANCA)-associated vasculitis (AAV) is a rare (estimated incidence of 3 cases per 100,000 per year) form ... [A240249, A240254] Despite complex pathophysiology, studies over the past ~2 decades have identified ... fragment C5a and its cognate C5aR receptor in AAV. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Rivaroxaban
Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15...
Approved
Matched Iupac: … 5-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl}thiophene-2-carboxamide …
Matched Description: … Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. ... The 15 mg and 20 mg tablet should be taken with food. FDA approved on July 1, 2011. …
Matched Categories: … Blood and Blood Forming Organs ... rivaroxaban and acetylsalicylic acid …
Matched Description: … Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. ... The 15 mg and 20 mg tablet should be taken with food. FDA approved on July 1, 2011. …
Matched Categories: … Blood and Blood Forming Organs ... rivaroxaban and acetylsalicylic acid …
Donepezil
In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Iupac: … 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one …
Matched Description: … Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination ... with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. ... derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Description: … Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination ... with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. ... derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Talazoparib
Talazoparib is an inhibitor of mammalian polyadenosine 5’-diphosphoribose polymerases (PARPs), enzymes responsible for regulating essential cellular functions, such as DNA transcription and DNA repair. Developed by Pfizer, talazoparib was first approved by the FDA in October 2018 and by the EMA in June 2019. It was approved by Health Canada...
Approved
Investigational
Matched Iupac: … (11S,12R)-7-fluoro-11-(4-fluorophenyl)-12-(1-methyl-1H-1,2,4-triazol-5-yl)-2,3,10-triazatricyclo[7.3.1.0 …
Matched Description: … (PARPs), enzymes responsible for regulating essential cellular functions, such as DNA transcription and ... L47236] Developed by Pfizer, talazoparib was first approved by the FDA in October 2018 [A260346] and ... [L47301] Talazoparib is currently used in the treatment of BRCA-mutated breast cancer and HRR-mutated …
Matched Salts cas: … 1373431-65-2 …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … (PARPs), enzymes responsible for regulating essential cellular functions, such as DNA transcription and ... L47236] Developed by Pfizer, talazoparib was first approved by the FDA in October 2018 [A260346] and ... [L47301] Talazoparib is currently used in the treatment of BRCA-mutated breast cancer and HRR-mutated …
Matched Salts cas: … 1373431-65-2 …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Micafungin
Micafungin is an antifungal drug. It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Approved
Investigational
Matched Iupac: … -tetrahydroxy-15-[(1R)-1-hydroxyethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-18-(4-{5-[4-(pentyloxy)phenyl ... {5-[(1S,2S)-2-[(3S,6S,9S,11R,15S,18S,20R,21R,24S,25S,26S)-3-[(1R)-2-carbamoyl-1-hydroxyethyl]-11,20,21,25 ... 3-yl}benzamido)-1,4,7,13,16,22-hexaazatricyclo[22.3.0.0^{9,13}]heptacosan-6-yl]-1,2-dihydroxyethyl]-2- …
Matched Description: … It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting …
Matched Salts cas: … 208538-73-2 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting …
Matched Salts cas: … 208538-73-2 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 176 - 200 of 375 in total