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Displaying drugs 2001 - 2025 of 2717 in total
Experimental
Matched Name: … Cmp-2-Keto-3-Deoxy-Octulosonic Acid
Matched Iupac: … (2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl ... )oxy]-6-[(1R)-1,2-dihydroxyethyl]-4,5-dihydroxyoxane-2-carboxylic acid
Experimental
Matched Name: … DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID
Experimental
Matched Name: … 5-[2-(TRIFLUOROMETHYL)PHENYL]-2-FUROIC ACID
Matched Iupac: … 5-[2-(trifluoromethyl)phenyl]furan-2-carboxylic acid
Experimental
Matched Name: … (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid
Matched Iupac: … (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid
Experimental
Matched Name: … 4-(2-HYDROXY-4-FLUOROPHENYLTHIO)-BUTYLPHOSPHONIC ACID
Matched Iupac: … [(1E)-4-[(5-fluoro-2-hydroxyphenyl)sulfanyl]but-1-en-1-yl]phosphonic acid
Experimental
Matched Name: … 1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID
Matched Iupac: … 1-phenyl-1H-pyrazole-4-carboxylic acid
Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
Approved
Investigational
Matched Synonyms: … 6β-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanic acid ... oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Iupac: … carbonyl)amino]-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Description: … It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and
A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Approved
Matched Synonyms: … 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and
Matched Categories: … norfloxacin and tinidazole ... norfloxacin and metronidazole ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … RENORF® TABLETAS POR 400 MG …
Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
Experimental
Withdrawn
Matched Synonyms: … (5-(4-fluorobenzoyl)-1H-benzimidazole-2-yl)carbamic acid methyl ester …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Acids, Acyclic ... Carboxylic Acids
Pelacarsen is under investigation in clinical trial NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo(a)-lrx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease).
Investigational
Matched Synonyms: … Isis-681257 (galnac3--conjugated aso targeting human lipoprotein (a)) free acid
Matched Description: … NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo(a)-lrx) in Participants With Hyperlipoproteinemia(a) and
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Iloprost is an analog of prostacyclin (PGI2; epoprostenol), an endogenous prostanoid mainly produced in the vascular endothelium. It is more stable than prostacyclin, which is short-lived. Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately 53:47. It is a potent vasodilator with reported...
Approved
Investigational
Matched Synonyms: … Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen-2(1H)-ylidene]pentanoic acid ... PENTANOIC ACID, 5-((3AS,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-((1E,3S)-3-HYDROXY-4-METHYL-1-OCTEN-6-YNYL)- ... )-hexahydro-5-hydroxy-4-[(E)-(3S,4RS)­ 3-hydroxy-4-methyl-1-octen-6-ynyl]-Δ2(1H),Δ-pentalenevaleric acid
Matched Iupac: … 6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2-ylidene]pentanoic acid
Matched Description: … [A263326] Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately ... [A263316] Iloprost is available as an inhaled solution and intravenous formulations. ... It is used to treat pulmonary arterial hypertension (PAH) [L50146] and frostbites.[L50151] …
Matched Categories: … Blood and Blood Forming Organs ... Fatty Acids ... Fatty Acids, Unsaturated …
Investigational
Matched Synonyms: … (1s,4r,5r,7s)-3, 4-dibenzyl-2-oxo-6, 8-dioxa-3-azabicyclo (3.2.1) octane-7-carboxylic acid ... 3, 4-dibenzyl-2-oxo-6, 8-dioxa-3-azabicyclo (3.2.1) octane-7-carboxylic acid, (1s,4r,5r,7s)- ... 6,8-dioxa-3-azabicyclo(3.2.1)octane-7-carboxylic acid, 2-oxo-3,4-bis(phenylmethyl)-, (1s,4r,5r,7s)- …
Matched Iupac: … (1S,4R,5R,7S)-3,4-dibenzyl-2-oxo-6,8-dioxa-3-azabicyclo[3.2.1]octane-7-carboxylic acid
Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Synonyms: … 6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid ... 4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid ... 4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda6-thieno[2,3-b]thiopyran-2-sulfonic acid amide …
Matched Description: … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA ... and other systemic adverse effects. ... ) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide HCl and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Investigational
Matched Synonyms: … (1,1'-biphenyl)-4-carboxylic acid, 2'-((1r)-1-((2r)-3-((2-(4-chloro-3-fluorophenyl)-1,1-dimethylethyl ... fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)ethyl)-3-methyl(1,1'-biphenyl)-4-carboxylic acid ... fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropyl)oxy)ethyl)-3-methyl-1,1'-biphenyl-4-carboxylic acid
Matched Iupac: … fluorophenyl)-2-methylpropan-2-yl]amino}-2-hydroxypropoxy]ethyl]-3-methyl-[1,1'-biphenyl]-4-carboxylic acid
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Approved
Vet approved
Matched Description: … An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … REDEXA ® DEXMEDETOMIDINA 100 MCG /ML POR 2 ML …
Experimental
Matched Synonyms: … (S)-α-amino-4-hydroxy-3,6-dioxo-1,4-cyclohexadiene-1-propanoic acid
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3,6-dioxocyclohexa-1,4-dien-1-yl)propanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic acid
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid
Matched Description: … sodium ions across cell membranes of the lungs, pancreas, and other organs. ... with CF worldwide, is known as F508del-CFTR, or delta-F508 (ΔF508), in which a deletion in the amino acid ... dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and
Matched Categories: … ivacaftor and lumacaftor …
Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central nervous system and peripherally in the gastrointestinal system. Agonism of peripheral...
Approved
Investigational
Matched Synonyms: … 2,6-dimethyl-L-phenylalanyl)[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino}methyl)-2-methoxybenzoic acid
Matched Iupac: … 2,6-dimethylphenyl)-N-[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]propanamido]methyl}-2-methoxybenzoic acid
Matched Description: … The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central ... Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid ... nervous system and peripherally in the gastrointestinal system. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the...
Approved
Matched Synonyms: … Pyroguaiac acid
Matched Description: … Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. ... Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. ... Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma. …
Gemfibrozil is a fibric acid agent, similar to clofibrate, used to treat Type IIb, IV, and V hyperlipidemias.[A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications. Gemfibrozil was granted FDA approval on 21...
Approved
Matched Synonyms: … 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid
Matched Iupac: … 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid
Matched Description: … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias ... responded adequately to weight loss, diet, exercise, and other medications. ... [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not …
Matched Categories: … Drug-Related Side Effects and Adverse Reactions ... Metabolic Side Effects of Drugs and Substances ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids
Investigational
Matched Synonyms: … chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)-4-pyrimidinyl)-2,8-diazaspiro(4.5)decane-3-carboxylic acid ... 2,8-diazaspiro(4.5)decane-3-carboxylic acid, 8-(2-amino-6-((1r)-1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2 ... chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-2,8-diazaspiro(4.5)decane-3-carboxylic acid
Matched Iupac: … -[1,1'-biphenyl]-2-yl}-2,2,2-trifluoroethoxy]pyrimidin-4-yl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid
Phytochlorin is under investigation in clinical trial NCT06311890 (Study to Evaluate the Efficacy, Safety and Tolerability of Photodynamic Therapy(pdt) With Chlorin-e6 in Treating Moderate to Severe Acne).
Investigational
Matched Synonyms: … 2-porphinepropionic acid, 18-carboxy-20-(carboxymethyl)-13-ethyl-2.beta.,3-dihydro-3.beta.,7,12,17-tetramethyl ... 21h,23h-porphine-2-propanoic acid, 18-carboxy-20-(carboxymethyl)-8-ethenyl-13-ethyl-2,3-dihydro-3,7,12,17 ... 21h,23h-porphine-7-propanoic acid, 3-carboxy-5-(carboxymethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17 …
Matched Description: … Phytochlorin is under investigation in clinical trial NCT06311890 (Study to Evaluate the Efficacy, Safety and
Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Synonyms: … (L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid ... (R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid
Matched Iupac: … )-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic acid
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Investigational
Matched Synonyms: … methyl(propyl)carbamoyl)oxy)methyl)-1h-1,2,3-triazol-4-yl)pyridin-3-yl)oxy)cyclohexane-1-carboxylic acid ... Cyclohexanecarboxylic acid, 3-((2-methyl-6-(1-methyl-5-((((methylpropylamino)carbonyl)oxy)methyl)-1h- …
Matched Iupac: … methyl(propyl)carbamoyl]oxy}methyl)-1H-1,2,3-triazol-4-yl]pyridin-3-yl}oxy)cyclohexane-1-carboxylic acid
Investigational
Matched Synonyms: … Synthetic Signal Peptide Of Human Mucin-1 (Amino Acids 1-21) …
Displaying drugs 2001 - 2025 of 2717 in total