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Displaying drugs 2051 - 2075 of 9055 in total
Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus. It was first introduced in 1984 and is available in various countries including Canada and the U.S. According to the 2018 Clinical Practice...
Approved
Investigational
Matched Synonyms: … 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea ... N-{4-[β-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea …
Matched Iupac: … N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-5-methylpyrazine-2-carboxamide …
Matched Description: … second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 ... cells for their therapeutic effectiveness, sulfonylureas are more commonly used for early-stage type 2
Approved
Experimental
Matched Synonyms: … 1,2-Distearoyl-sn-glycero-3-phosphocholine …
Matched Iupac: … (2-{[2,3-bis(octadecanoyloxy)propyl phosphonato]oxy}ethyl)trimethylazanium …
Lauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression. Lauric acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can be treated with various solutes and used to determine their molecular masses.
Approved
Experimental
Matched Synonyms: … C12:0
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric...
Approved
Investigational
Matched Synonyms: … N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4,5-trimethoxybenzamide …
Matched Iupac: … N-({4-[2-(dimethylamino)ethoxy]phenyl}methyl)-3,4,5-trimethoxybenzamide …
Matched Salts cas: … 554-92-7
Matched Products: … VOMET 2 ML 200 MG 6 AMPUL ... VOSELMIT 200 MG 2 ML 6 AMPUL ... EMEDUR 200 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 50 ADET …
Approved
Experimental
Testosterone propionate is a slower-releasing anabolic steroid with a short half-life. It is a synthetic androstane steroid derivative of testosterone in the form of 17β propionate ester of testosterone. Testosterone propionate was developed initially by Watson labs, and FDA approved on February 5, 1974. Currently, this drug has been discontinued...
Approved
Investigational
Vet approved
Withdrawn
Matched Iupac: … (1S,3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta …
Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).
Approved
Matched Synonyms: … 1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol ... (±)-4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate ... 4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate …
Matched Iupac: … 2-[(2,2-dimethylpropanoyl)oxy]-5-[1-hydroxy-2-(methylamino)ethyl]phenyl 2,2-dimethylpropanoate …
Matched Categories: … Adrenergic beta-3 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic beta-2 Receptor Agonists …
A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.
Approved
Investigational
Matched Synonyms: … 1,4-Dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycin XIV ... 4-Deoxo-3,4-(2-spiro(N-isobutyl-4-piperidyl)-2,5-dihydro-1H-imidazo)-rifamycin S …
Matched Iupac: … methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1^{4,7}.0^{5,31}.0^{26,30 ... 12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2- …
Onasemnogene abeparvovec is an adeno-associated virus vector-based gene therapy that has been approved by the FDA in May 2019 for the treatment of infant patients (less than 2 years of age) with spinal muscular atrophy (SMA) and a specific mutation in the survival motor neuron 1 (SMN1) gene. SMA is...
Approved
Matched Description: … therapy that has been approved by the FDA in May 2019 for the treatment of infant patients (less than 2
Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It may also be found in some Cepacol sore throat spray products.
Approved
Matched Synonyms: … 2-(1-piperidyl)ethyl p-butoxyphenyl ketone ... 3-piperidino-4'-butoxypropiophenone ... 4'-butoxy-3-piperidinopropiophenone …
Matched Iupac: … 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one …
Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Synonyms: … (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol ... 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole …
Matched Iupac: … (2-butyl-4-chloro-1-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol …
Matched Categories: … Angiotensin 2 Receptor Blocker ... Angiotensin II Type 2 Receptor Blockers …
Matched Products: … ARA 2
Nadolol is a nonselective beta adrenal receptor blocker that is used to lower blood pressure.[L7922,L7925] Nonselective beta adrenal receptor blockers may no longer be first line in the treatment of hypertension as newer generations of beta adrenal receptor blockers have higher selectivity and offer better rates of adverse effects. Nadolol...
Approved
Matched Iupac: … (2R,3S)-5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol …
Matched Categories: … MATE 2 Substrates …
Polyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 g/mol. It is a clear viscous liquid at room temperature with non-volatile, stable properties . Polyethylene glycols are widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries. They...
Approved
Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications.[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the...
Approved
Investigational
Vet approved
Matched Iupac: … 3-[(2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethylpyrrolidin-1-ium …
Abametapir is a novel pediculicidal metalloproteinase inhibitor used to treat infestations of head lice. The life cycle of head lice (Pediculus capitis) is approximately 30 days, seven to twelve of which are spent as eggs laid on hair shafts near the scalp. Topical pediculicides generally lack adequate ovicidal activity, including...
Approved
Investigational
Matched Description: … including standard-of-care treatments such as [permethrin], and many require a second administration 7- …
Pentafluoropropane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).
Approved
Investigational
A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Mixtures name: … 7 Select Hemorrhoidal Original Strength ... CARMEX Multi-Symptom 3 in 1 COLD Sore treatment External Analgesic Skin Protectant …
Matched Products: … PROVON Perineal Skin Protectant with 60% Petrolatum …
Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis.[A253942,L43752] The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood. It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor...
Approved
Investigational
Matched Synonyms: … (E)-But-2-enedioic acid dimethyl ester …
Matched Iupac: … 1,4-dimethyl (2E)-but-2-enedioate …
Matched Description: … -like 2 (Nrf2) pathway that is activated in response to oxidative stress. ... active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2) …
A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Synonyms: … 2-Diethylaminoethyl p-aminobenzoate ... 4-aminobenzoic acid 2-diethylaminoethyl ester ... p-Aminobenzoic acid 2-diethylaminoethyl ester …
Matched Iupac: … 2-(diethylamino)ethyl 4-aminobenzoate …
Matched Salts cas: … 6192-92-3 ... 54812-66-7
Matched Products: … Novocain Liq 2% ... PROCANOL LOTION 2% ... VERSENIKCAINA® 2% …
Approved
Matched Synonyms: … Phosphoric acid, sodium salt (1:2) …
Matched Salts cas: … 10028-24-7
Matched Mixtures name: … Phoxillum B22k4/0 ... Aminosyn II 7% M In 10% Dextrose(dual Chamber) …
Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been...
Approved
Vet approved
Matched Synonyms: … 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol …
Matched Iupac: … 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol …
Matched Salts cas: … 51-42-3 ... 55-31-2
Matched Mixtures name: … Zone 2 ... NEWCAINA 2% ... ไลเคน- เอ 2% …
Matched Categories: … Adrenergic beta-3 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic beta-2 Receptor Agonists …
Matched Products: … Gingi-pak Max Z-twist No 3 ... Gingi-pak Max Soft-twist No 3 ... Gingi-pak Max 2-ply …
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Iupac: … }.0^{4,7}]heptadec-13-en-2-yl benzoate ... (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy ... -3-phenylpropanoyl]oxy}-1,9,12-trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^{3,10 …
Matched Products: … TAXESPIRA® 20 MG / 2 ML ... LILDOCEX 40 MG/ ML (80 MG/2 ML) ... DOCETAXEL 80 MG / 2 ML SOLUCION INYECTABLE …
Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor (G-CSF) analog produced by recombinant DNA technology. It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in E. Coli. Human...
Approved
Matched Description: … L36325] Filgrastim-sndz was approved on March 6, 2015 [L40768] and filgrastim-ayow was approved on March 2, …
Matched Products: … FRAVEN 30 MIU/0,5 ML IV INFUZYON/SC ENJEKSIYON ICIN COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR, 3 ADET …
Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure prophylaxis against rabies.
Approved
Displaying drugs 2051 - 2075 of 9055 in total