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Displaying drugs 2101 - 2125 of 3016 in total
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Description: … Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... It has a significant impact on both the physical and social functioning of affected individuals. …
Matched Products: … MARAK
Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Matched Description: … [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as …
Matched Mixtures name: … Oxycodone-acet ... Oxycodone/acet ... Nu-oxycodone/acet
Matched Categories: … oxycodone and acetylsalicylic acid ... oxycodone and naloxone ... oxycodone and naltrexone ... oxycodone and ibuprofen ... oxycodone and paracetamol …
Matched Products: … OXYCODON-HCL-ACINO 10MG ... OXYCODON-HCL-ACINO 20MG ... OXYCODON-HCL-ACINO 40MG …
Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched Synonyms: … 11α,15α-dihydroxy-9-oxo-13-trans-prostenoic acid ... (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid
Matched Iupac: … 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid
Matched Description: … intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and ... This drug causes vasodilation by directly affecting vascular and ductus arteriosus (DA) smooth muscle …
Matched Categories: … Genito Urinary System and Sex Hormones ... Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
Experimental
Matched Synonyms: … 1H-Indeb5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]cyclohexanecarboxylic acid ... indan-5-yloxycarbonyl)-3-(2-methoxy-ethoxy)-propyl]-cyclopentanecarbonyl}-amino)-cyclohexanecarboxylic acid
Matched Iupac: … 1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentaneamido}cyclohexane-1-carboxylic acid
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Synonyms: … syn-7-(2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid ... Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Iupac: … 1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … of both aerobic and anaerobic gram-positive and gram-negative organisms. ... It has few side effects and is reported to be safe and effective in aged patients and in patients with ... The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range …
Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid ... 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. ... It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. ... Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. …
A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.
Experimental
Matched Synonyms: … (R)-2-Amino-3-(p-hydroxyphenyl)propionic acid
Matched Iupac: … (2R)-2-amino-3-(4-hydroxyphenyl)propanoic acid
Matched Description: … It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. ... A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. …
Approved
Investigational
Matched Synonyms: … Sulfuric acid, dipotassium salt …
Matched Mixtures name: … Multiple Vitamins and Minerals Capsules ... Sodium Sulfate, Potassium Sulfate and Magnesium Sulfate ... Sodium Sulfate, Potassium Sulfate and Magnesium Sulfate …
Matched Categories: … Sulfur Acids ... Sulfuric Acids
Investigational
Matched Synonyms: … 5-(3,5-Dimethyl-4-hydroxybenzylamino)-3-(4-morpholin-4-yl-phenylamino)-1H-pyrazole-4-carboxylic acid
Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). Additionally, it has been employed for the prophylaxis of UTIs prior to surgery as well.
Approved
Investigational
Matched Synonyms: … (±)-1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid ... 1,4-Dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
Matched Iupac: … 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and
Perenostobart is an alpha-CD39 IgG4 monoclonal antibody.
Investigational
Matched Synonyms: … ectonucleoside triphosphate diphosphohydrolase 1, NTPDase-1, ATPDase, SPG64, CD39)], Homo sapiens monoclonal antibody
Matched Description: … Perenostobart is an alpha-CD39 IgG4 monoclonal antibody. …
Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize. Beta-blockers quickly became popular in clinical use and where subsequently investigated for...
Approved
Matched Description: … use in myocardial infarction, arrhythmias, and hypertension during the 1960s. ... [A178429] Beta-blockers quickly became popular in clinical use and where subsequently investigated for ... Atenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and
Matched Mixtures name: … Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone …
Matched Categories: … Beta Blocking Agents and Thiazides ... Beta blocking agents and calcium channel blockers ... atenolol and nifedipine ... atenolol and thiazides ... Beta Blocking Agents, Selective, and Thiazides …
Matched Products: … Mar-atenolol ... ALONET 50 TABLET 50 mg (REVISED FORMULA) ... ALONET 100 TABLET 100 mg (REVISED FORMULA) …
Experimental
Matched Synonyms: … 2-Amino-4-(guanidinooxy)butyric acid
Matched Iupac: … (2S)-2-amino-4-(carbamimidamidooxy)butanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Experimental
Matched Synonyms: … 5-{2-fluoro-5-[3-(3-hydroxy-2-methoxycarbonyl-phenoxy)-propenyl]-phenyl}-isoxazole-3-carboxylic acid
Matched Name: … Fluoro-5-{(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]-1-propen-1-yl}phenyl)-1,2-oxazole-3-carboxylic acid
Matched Iupac: … fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]prop-1-en-1-yl]phenyl}-1,2-oxazole-3-carboxylic acid
N-Formylmethionine is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.
Experimental
Matched Synonyms: … (2S)-2-(formylamino)-4-(methylthio)butanoic acid
Matched Iupac: … (2S)-2-formamido-4-(methylsulfanyl)butanoic acid
Matched Description: … This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Sulfur …
Camptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Experimental
Matched Synonyms: … 21,22-Secocamptothecin-21-oic acid lactone …
One of the furans with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.
Experimental
Illicit
Matched Synonyms: … 4-hydroxybutyric acid lactone …
Matched Description: … It is also used as a pharmacological agent and solvent. ... It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate …
Andrographolide (HMPL-004) is a botanical product extracted from a herb that occurs naturally in China. The herb has an extensive history of use in TCM for the treatment of upper respiratory tract infections and other inflammatory and infectious diseases.
Investigational
Matched Synonyms: … 3α,14,15,18-tetrahydroxy-5b,9bH,10a-labda-8(20),12-dien-16-oic acid γ-Lactone …
Matched Description: … other inflammatory and infectious diseases. ... herb has an extensive history of use in TCM for the treatment of upper respiratory tract infections and
EHT 0202 is developed to treat neurodegenerative disorders by ExonHit Therapeutics.
Investigational
Matched Synonyms: … 1H-PYRAZOLO(3,4-B)PYRIDINE-5-CARBOXYLIC ACID, 1-ETHYL-4-((1-METHYLETHYLIDENE)HYDRAZINO)-, ETHYL ESTER …
Matched Categories: … Acids, Heterocyclic ... Nicotinic Acids
Technetium Tc-99m oxidronate, also known as 99mTc-methylene diphosphonate, is a radiopharmaceutical agent. A radiopharmaceutical is defined as a medicinal formulation containing radioisotopes that are used in major clinical areas for diagnosis and/or therapy. The radiopharmaceuticals based on technetium-99m are widely used for diagnostic purposes because 99mTc has a versatile chemistry...
Approved
Matched Synonyms: … Oxidronic acid 99mtc-complex …
Matched Iupac: … [hydroxy(phosphono)methyl]phosphonic acid (⁹⁹Tc)technetium …
Matched Description: … clinical areas for diagnosis and/or therapy. ... [L1140] It was developed by Mallinkrodt nuclear and FDA approved on February 18, 1981. ... radiopharmaceutical is defined as a medicinal formulation containing radioisotopes that are used in major
Matched Categories: … technetium (99mTc) oxidronic acid
SR-9009 is a REV-ERB agonist. SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues .
Experimental
Matched Synonyms: … 1-Pyrrolidinecarboxylic acid, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-, …
Matched Description: … SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent ... cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues [A32628 …
Benzylparaben is used in allergenic testing.
Approved
Experimental
Matched Synonyms: … p-Hydroxybenzoic acid benzyl ester …
Matched Categories: … Hydroxy Acids ... Acids, Carbocyclic ... Carboxylic Acids
Experimental
Matched Synonyms: … 3-[18-(2-Carboxyethyl)-7,12-diethyl-3,8,13,17,23-pentamethylporphyrin-21-id-2-yl]propanoic acid;copper …
Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity .
Approved
Matched Synonyms: … 3-(4-Methoxyphenyl)-2-propenoic acid, 3-methylbutyl ester …
Matched Description: … Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916]. …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Vet approved
Matched Synonyms: … 1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester …
Matched Description: … It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Displaying drugs 2101 - 2125 of 3016 in total