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Displaying drugs 201 - 225 of 9190 in total

Oteseconazole

Oteseconazole is an azole metalloenzyme inhibitor that targets fungal CYP51. CYP51, also known as 14α demethylase, participates in the formation of ergosterol, a compound that plays a vital role in the integrity of cell membranes.[L41635,A247020] By binding and inhibiting CYP51, oteseconazole is active against most microorganisms associated with recurrent vulvovaginal...
Approved
Investigational
Matched Synonyms: … (R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin …
Matched Iupac: … (2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,3,4-tetrazol-1-yl)-1-{5-[4-(2,2,2-trifluoroethoxy) …

Urea

A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Approved
Investigational
Matched Mixtures name: … Ciclopirox 3% / Itraconazole 5% / Urea 20% ... Psoricare Crm 3% ... Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% …
Matched Products: … Bare 20 ... Urea 20 ... CARMED 20 …

Cladribine

Cladribine is a purine analogue or a chlorinated derivative of adenine that causes apoptosis of B and T lymphocytes. Cladribine was first approved in the United States in 1993 initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell leukemia....
Approved
Investigational
Matched Synonyms: … (2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol …
Matched Iupac: … (2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol …

Pasireotide

Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Iupac: … 3S,6R,9S,12S,15S,19R,20aS)-9-(4-aminobutyl)-15-benzyl-12-{[4-(benzyloxy)phenyl]methyl}-6-[(1H-indol-3- ... yl)methyl]-1,4,7,10,13,16-hexaoxo-3-phenyl-icosahydropyrrolo[1,2-a]1,4,7,10,13,16-hexaazacyclooctadecan …
Matched Products: … SIGNIFOR 0.3 MG/1 ML ENJEKSIYONLUK ÇÖZELTI ,3 AMPUL ... SIGNIFOR® LAR 20 MG ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …

Leucovorin

Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin) is the 5-formyl derivative of tetrahydrofolic acid, a necessary co-factor in the body. Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the...
Approved
Matched Mixtures name: … KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 20 FLK. …
Matched Products: … NYRIN INJECTION 3 mg/ml ... KALSIYUM FOLINAT EBEWE 30 MG/3 ML ENJEKTABL ÇÖZELTİ İÇEREN AMPUL, 5 ADET ... KALSİFOSİN 200 MG/20 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …

Somatostatin

Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where...
Approved
Investigational
Matched Iupac: … 13,25,28-tribenzyl-31-(carbamoylmethyl)-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-[(1H-indol-3- …
Matched Products: … STILAMIN 3000 FOR INJECTION 3 mg/ampoule ... SOMATOSAN 3 MG IV INFUZYON ICIN 1 AMPUL ... Somatin 3 mg - Pulver zur Herstellung einer Infusionslösung …

Ceftizoxime

A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Synonyms: … syn-7-(2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid …

Spiramycin

Spiramycin is a primarily bacteriostatic macrolide antimicrobial agent with activity against Gram-positive cocci and rods, Gram-negative cocci and also Legionellae, mycoplasmas, chlamydiae, some types of spirochetes, Toxoplasma gondii and Cryptosporidium. Spiramycin is a 16-membered ring macrolide discovered in 1952 as a product of Streptomyces ambofaciens that has been available in...
Approved
Matched Iupac: … )-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy}-4-(dimethylamino)-3- …
Matched Mixtures name: … Stomorgyl 20 Tablet …
Matched Products: … ESPIRAMICINA 3 M.U.I. TABLETA RECUBIERTA ... ROVAGYL 3 MIU FILM KAPLI TABLET, 14 ADET ... ROVAGYL 3 MIU FILM KAPLI TABLET, 10 ADET …

Clotrimazole

This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Mixtures name: … KADEFUNGIN 3 ... KADEFUNGIN 3 ... CANESTEN GYN 3 …
Matched Products: … CANESTEN %1 KREM, 20 G ... CANDID - V 3 ... KADEFUNGIN 3 …

Dextrose, unspecified form

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Vet approved
Matched Mixtures name: … Additive Solution Formula 3 As-3 ... Potassium Chloride 20 Meq In 5% Dextrose ... As-3 …
Matched Products: … 20% Dextrose Injection USP ... 20% Dextrose Injection, USP ... %20 DEKSTROZ VAC.500 ML(SETLI) …

Diethylstilbestrol

A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed) The FDA withdrew its...
Approved
Investigational
Withdrawn
Matched Synonyms: … (E)-3,4-bis(4-hydroxyphenyl)-3-hexene …
Matched Iupac: … 4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol …

Ephedrine

Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons,...
Approved
Matched Salts cas: … 1405-94-3 …
Matched Products: … EFEDRIN ARSAN TABLET, 20 ADET ... Ephedrinhydrochlorid Aguettant 3 mg/ml Injektionslösung in Fertigspritze …

Carteolol

A beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.
Approved
Matched Iupac: … 5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydroquinolin-2-one …
Matched Products: … CARTEOL LP %1 UZUN ETKILI GOZ DAMLASI, 3 ML ... CARTEOL LP %2 UZUN ETKILI GOZ DAMLASI, 3 ML …

Chlortetracycline

Chlortetracycline is a tetracycline antibiotic, and historically the first member of this class to be identified. It was discovered in 1945 by the scientist, Benjamin Minge Duggar, working at Lederle Laboratories under the supervision of Yellapragada Subbarow. He discovered that this antibiotic was the product of an actinomycete strain he...
Approved
Investigational
Vet approved
Matched Salts cas: … 57122-99-3 …
Matched Products: … Aureomycin Ont 3% ... Aureomycin - Ont Top 3% …

Piretanide

Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of other aromatically bonded functional groups.
Approved
Matched Iupac: … 4-phenoxy-3-(pyrrolidin-1-yl)-5-sulfamoylbenzoic acid …
Matched Products: … ARELIX MITE 3 ... PIRETANID 3 1A PHARMA …

Betamethasone

Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Approved
Vet approved
Matched Salts cas: … 5593-20-4 …
Matched Mixtures name: … Fusicutan 20 mg/g + 1 mg/g Creme ... Fucibet Lipid 20 mg/g + 1 mg/g Creme ... FUCICORT 20 MG/G + 1 MG/G KREM, 30 G …
Matched Products: … BEKORTEN GÖZ POMADI, 3 G ... NOVOVATE LOSYON, 20 ML ... BETNOVATE LOSYON, 20 ML …

Cariprazine

Cariprazine is an atypical antipsychotic agent and a piperazine derivative that was first developed in Hungary. It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT1A receptors and as an antagonist at serotonin 5-HT2A receptors. Cariprazine has been investigated in a variety of psychiatric disorders,...
Approved
Investigational
Matched Products: … รีกิลา 3 ม.ก. ... REAGİLA 3 MG SERT KAPSÜL, 28 ADET ... REAGİLA 3 MG SERT KAPSÜL, 30 ADET …

Ornithine

Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine. L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.
Approved
Nutraceutical
Matched Products: … Hepa-Merz 3 g Granulat ... HEPAMONIA 3 G GRANÜL, 30 ADET ... HEPA-ORNİTAT 3 G GRANÜL, 30 ADET …

Dexamethasone

Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Mixtures name: … Rheumesser 3 ml - Ampullen ... DEXAVITAL TOBRAMICIDADEXAMETASONA(3 MG+1MG)/ML ... NETILDEX GOZ DAMLASI %0,1 DEKSAMETAZON + %0,3 NETILMISIN 0,3 ML × 20 ADET …
Matched Products: … DEKORT 4 MG TABLET, 20 ADET ... DEKORT 8 MG TABLET, 20 ADET ... KORDEXA 4 MG TABLET, 20 ADET …

Erdafitinib

In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for patients with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing...
Approved
Investigational
Matched Iupac: … N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-{2-[(propan-2-yl)amino]ethyl}quinoxalin-6-amine …
Matched Products: … BALVERSA 3 MG FİLM KAPLI TABLET, 56 ADET ... BALVERSA 3 MG FİLM KAPLI TABLET, 84 ADET …

Frovatriptan

Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
Approved
Investigational
Matched Iupac: … (3R)-3-(methylamino)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamide …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … NEWART 2.5 MG TABLET, 3 ADET ... MIGREX 2.5 MG FILM TABLET, 3 ADET …

Zinc sulfate

Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Approved
Investigational
Matched Salts cas: … 7446-20-0 …
Matched Mixtures name: … Visine for Allergy 3 Symptom Relief ... FERROZINC KAPSUL, 20 ADET ... IROZINC KAPSÜL ,20 KAPSÜL …
Matched Products: … RZ-20 ... ZINKIT 20 ... ZINK 20 AAA PHARMA DRAGEES …

Mepolizumab

Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically defined as absolute eosinophil levels of 1500/mm3 or more) is associated with a spectrum of diseases, including severe asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and hypereosinophilic syndrome (HES). The pathogenesis of eosinophilia is complex, but IL-5 is recognized as...
Approved
Investigational
Matched Description: … responses, and prolonged hypereosinophilia (typically defined as absolute eosinophil levels of 1500/mm3< …
Matched Products: … NUCALA 100 MG SUBKUTAN ENJEKSİYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ, 3 ADET ... NUCALA 100 MG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 3 ADET …

Nirogacestat

Nirogacestat is a small-molecule gamma-secretase inhibitor that was investigated as a potential treatment for desmoid tumors. Desmoid tumors are typically characterized by aberrant activation in Notch signaling. Interaction between the notch receptors and their ligands activates proteolytic cleavage by gamma-secretase; therefore, the inhibition of gamma-secretase can potentially inhibit Notch signaling...
Approved
Investigational
Matched Description: … treatment of desmoid tumors, and the final approval was based on positive results obtained in the Phase 3 …

alpha-Tocopherol acetate

Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Matched Description: … IU) females = 5 mg (7.5 IU) in ages 7-12 months, males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 …
Matched Mixtures name: … Folcaps Omega-3 ... PNV Tabs 20-1 ... Vitamin A (100,000 Iu) and Vitamin E (20 Iu) Oral Liquid Preparation …
Matched Products: … EVIGEN AMPUL, 3 ADET ... ENJEKSIYON IÇIN ÇÖZELTI IÇEREN AMPUL ,3 AMPUL ... EVİGEN 300 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 3 ADET …
Displaying drugs 201 - 225 of 9190 in total