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Displaying drugs 201 - 225 of 14564 in total
Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by...
Approved
Illicit
Matched Iupac: … 12-chloro-9-(2-fluorophenyl)-3-methyl-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,8,11,13- …
Matched Description: … [L45098] In late 2018, the intramuscular preparation was approved by the FDA for the treatment of status ... [A257153] Midazolam is considered a schedule IV drug in the United States due to the low potential for ... [L45098] In May 2019, the nasal spray of midazolam was approved for the acute treatment of distinctive …
Matched Products: … N/a ... Midazolam Accord 1 mg/ml Injektions-/Infusionslösung in einer Fertigspritze ... Midazolam in Sodium Chloride …
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … stability of F508del-mutated CFTR proteins, preventing misfolding and resulting in increased processing ... , or delta-F508 (ΔF508), in which a deletion in the amino acid phenylalanine at position 508 results ... Mutations in the CFTR gene result in altered production, misfolding, or function of the CFTR protein …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Risankizumab is a fully humanized IgG1 monoclonal antibody (mAb) directed against interleukin 23 (IL-23). It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019. Risankizumab is used to treat plaque psoriasis, psoriatic arthritis, and Crohn's disease.[L39885,L44191,L44231] Risankizumab...
Approved
Investigational
Matched Description: … the US, and Europe in April 2019. ... [L39885] It gained its first global approval in Japan in March 2019, followed by approval in Canada, ... Risankizumab is a fully humanized IgG1 monoclonal antibody (mAb) directed against interleukin 23 (IL- …
Matched Products: … Skyrizi 150 mg/ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 1 ADET ... SKYRİZİ 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... Skyrizi 75 mg solution for injection in pre-filled syringe …
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Approved
Investigational
Vet approved
Matched Synonyms: … (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid ... 1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid ... 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid …
Matched Iupac: … 2-{1,8-diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl}acetic acid …
Matched Description: … It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. ... Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic …
Tegafur-uracil is an anti-tumor compound containing tegafur (1-(2-tetrahydrofuryl)-5-fluorouracil) and uracil in a molar ratio of 1:4. It was developed as an anti-cancer therapy by Taiho Pharmaceutical Co Ltd. It is approved in different countries but it is not yet approved by the FDA, Health Canada or EMA.
Approved
Investigational
Matched Iupac: … 1,2,3,4-tetrahydropyrimidine-2,4-dione; 5-fluoro-1-(oxolan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … uracil in a molar ratio of 1:4. ... [A32073] It is approved in different countries but it is not yet approved by the FDA, Health Canada or ... It was developed as an anti-cancer therapy by Taiho Pharmaceutical Co Ltd. …
Kaolin is a layered silicate mineral. Kaolin is used in ceramics, medicine, coated paper, as a food additive, in toothpaste, as a light diffusing material in white incandescent light bulbs, and in cosmetics. Until the early 1990s it was the active substance of anti-diarrhoea medicine Kaopectate.
Approved
Matched Description: … Until the early 1990s it was the active substance of anti-diarrhoea medicine Kaopectate. ... Kaolin is used in ceramics, medicine, coated paper, as a food additive, in toothpaste, as a light diffusing ... Kaolin is a layered silicate mineral. …
Matched Mixtures name: … Kaolin Mixture W Pectin Nf
Matched Products: … Sonatural The Pure Pore Tensing Carbonic Bubble Pop Clay Mask …
Icatibant is a synthetic decapeptide with 5 nonproteinogenic amino acid antagonist targeting the B2 receptors with a similar affinity to bradykinin. It is resistant to bradykinin-cleaving enzyme degradation and has a potency of 2-3 times higher than earlier B2 receptors antagonists, thus representing a new class of medication.[A4017,A263041] It was...
Approved
Investigational
Matched Description: … [A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a ... , controlled clinical trials known as FAST 1, 2, and 3, where a median time to almost complete symptom ... , thus demonstrating bradykinin involvement in the disease pathophysiology. …
Matched Categories: … Drugs Used in Hereditary Angioedema …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... İKTU 30 MG/3 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle. Calcium Gluconate Injection,...
Approved
Vet approved
Matched Synonyms: … D-gluconic acid, calcium salt (2:1) …
Matched Description: … Each 10 mL of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate ... It can also be taken by mouth but is not recommended by injection into a muscle. ... Calcium saccharate provides 6% of the total calcium and stabilizes the supersaturated solution of calcium …
Matched Products: … Calcium Gluconate in Sodium Chloride ... 2% Calcium Gluconate In Sodium Chloride Injection …
Potassium hydroxide, also known as lye is an inorganic compound with the chemical formula KOH. Also commonly referred to as caustic potash, it is a potent base that is marketed in several forms including pellets, flakes, and powders. It is used in various chemical, industrial and manufacturing applications. Potassium hydroxide...
Approved
Matched Description: … by the FDA, based upon the observance of several good manufacturing practice conditions of use. ... Recently, it has been studied for efficacy and tolerability in the treatment of warts. ... Medically, potassium hydroxide (KOH) is widely used in the wet mount preparation of various clinical …
Matched Mixtures name: … Aminomix 1 Novum - Infusionslösung ... Kalium-L-malat "Fresenius" 1 molar - Infusionszusatz - Ampullen ... NUTRIFLEX PERI IN 2000ML TWIN-FLEX …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … MIRACLE WATER 3 in 1
C1 Esterase Inhibitor (Human) is composed of purified endogenous complement component-1 esterase inhibitor (hC1INH) isolated from human plasma. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways.[L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a...
Approved
Matched Description: … ), a human genetic disorder caused by a shortage of C1 inhibitor activity that results in an overreaction ... The disease is characterized by acute attacks of painful, and in some cases, fatal swelling of several ... C1 Esterase Inhibitor (Human) is composed of purified endogenous complement component-1 esterase inhibitor …
Matched Categories: … Drugs Used in Hereditary Angioedema …
Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness preceding suicide.[L5596,A175462] On March 5, 2019, the nasal spray drug, esketamine, also known as Spravato (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression. Esketamine is the s-enantiomer of Ketamine. Ketamine...
Approved
Investigational
Matched Iupac: … (2S)-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one …
Matched Description: … The FDA approved ketamine (Ketalar) in 1970. ... Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness ... The intranasal route of administration for this drug allows for easy administration and a fast onset …
Matched Products: … Eskelan 25 mg/ml-Injektions-/Infusionslösung in Ampullen ... Eskelan 25 mg/ml-Injektionslösung in Durchstechflaschen ... Eskelan 5 mg/ml-Injektionslösung in Durchstechflaschen …
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Approved
Matched Description: … Produced in E. coli, no carbohydrates, MW=18.5kD …
Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.[A260746, L47556] Lotilaner consists of two enantiomers: the S-enantiomer is active in vivo, while the R-enantiomer is...
Approved
Vet approved
Matched Description: … Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. ... The active ingredient found in drug products of lotilaner is the S-enantiomer. ... [A260741] On July 25, 2023, lotilaner was approved by the FDA for the treatment of Demodex blepharitis …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Avena sativa flowering top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Avena sativa flowering top is a plant/plant extract used in some OTC (over-the-counter) products. …
Tegafur (INN, BAN, USAN) is a prodrug of DB00544 (5-FU), an antineoplastic agent used as the treatment of various cancers such as advanced gastric and colorectal cancers. It is a pyrimidine analogue used in combination therapies as an active chemotherapeutic agent in conjunction with DB09257 and DB03209, or along with...
Approved
Investigational
Matched International brands: … S-1 ... TS-1 ... NKS-1 T …
Matched Synonyms: … 1-(2-Tetrahydrofuryl)-5-fluorouracil …
Matched Iupac: … 5-fluoro-1-(oxolan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … by blocking the enzyme responsible for its degradation, or serves to limit the toxicity of 5-FU by ensuring ... Tegafur is usually given in combination with other drugs that enhance the bioavailability of the 5-FU ... Tegafur (INN, BAN, USAN) is a prodrug of [DB00544] (5-FU), an antineoplastic agent used as the treatment …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Dimercaprol is a traditional chelating agent developed by British biochemists at Oxford University during World War II. It was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning. In addition, it has in the past...
Approved
Matched International brands: … Bal In Oil Injection …
Matched Synonyms: … 2,3-dimercapto-1-propanol ... 2,3-mercaptopropan-1-ol ... 2,3-dimercaptol-1-propanol …
Matched Iupac: … 2,3-disulfanylpropan-1-ol …
Matched Description: … In addition, it has in the past been used for the treatment of Wilson's disease, a genetic disorder in ... Dimercaprol has toxic potential, and its use may be followed by a variety of adverse effects. ... Dimercaprol is a traditional chelating agent developed by British biochemists at Oxford University during …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … BAL in Oil ... Bal In Oil 3ml Ampules/10 …
One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Approved
Matched Description: … Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating ... One of the catecholamine neurotransmitters in the brain. ... A family of receptors (receptors, dopamine) mediate its action. …
Matched Mixtures name: … Dopamine Hydrochloride in Dextrose ... Dopamine Hydrochloride in Dextrose ... Dopamine Hydrochloride in Dextrose …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Selective Beta 1-adrenergic Agonists ... Monoamine Oxidase A Substrates …
Matched Products: … Dopamine Hci In 5% Dextrose ... Dopamine Hydrochloride in Dextrose ... MULTİFLEX DOPASEL 800 MCG/ML IV İNFÜZYON İÇİN ÇÖZELTİ, 1 ADET …
Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Approved
Investigational
Matched Iupac: … 4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl)methyl]benzonitrile …
Matched Description: … Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the ... literature in 1990. ... [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … SOLESTRASA-IN
Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Synonyms: … (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b ... (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido( …
Matched Iupac: … ,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1( …
Matched Description: … Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction ... [L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. ... a longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Drugs Used in Erectile Dysfunction ... Drugs Used in Benign Prostatic Hypertrophy …
Matched Products: … N/A
Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and apoptosis of cancer cells,...
Approved
Investigational
Matched Synonyms: … N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide ... [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid …
Matched Iupac: … [(1R)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid …
Matched Description: … by the FDA under the trade name VELCADE. ... [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome ... [L14180] However, multiple mechanisms may be involved in the anticancer activity of bortezomib. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …
Matched Products: … BORTECADE 1 ... Bortirel 1 mg IV Enjeksiyonluk Çözelti Hazırlamak İçin Toz, 1 ADET ... PORIX® 3.5 POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief...
Approved
Investigational
Matched Description: … [A180172] Nitroglycerin is used in a variety of different conditions, including angina pectoris due ... [A249965] Originally used to dynamite, its antianginal effects were identified in the late 1860s after ... [L38369] that was first discovered in 1847. …
Matched Mixtures name: … Nitroglycerin In 5% Dextrose Inj.-400mcg/ml ... Nitroglycerin In 5% Dextrose Inj.-200mcg/ml ... Nitroglycerin In 5% Dextrose Inj.-100mcg/ml …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Vasodilators Used in Cardiac Diseases …
Matched Products: … Nitroglycerin in Dextrose ... Nitroglycerin In Dextrose ... NITRONAL 1 MG/1 ML IV INFUZYON ICIN SOLUSYON ICEREN AMPUL, 5 ML 10 ADET …
Mecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in that both drugs contain recombinant DNA origin insulin-like growth factor 1 (IGF-1). Mecasermin rinfabate however,...
Approved
Matched Description: … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in ... patients with GH gene deletion who have developed antibodies to growth hormone (GH)[A176020]. ... In 2007 Insmed withdrew their application for a marketing authorization with The European Medicines Agency …
Methylephedrine is a sympathomimetic amine that appears in various over-the-counter cough and cold medications throughout the world , , . The abuse of methylephedrine-containing medications has been reported in Japan. Methylephedrine is not legally available in the United States, but has been identified in cases of drug abuse .
Approved
Matched Iupac: … (1R,2S)-2-(dimethylamino)-1-phenylpropan-1-ol …
Matched Description: … Methylephedrine is a sympathomimetic amine that appears in various over-the-counter cough and cold medications ... The abuse of methylephedrine-containing medications has been reported in Japan. ... Methylephedrine is not legally available in the United States, but has been identified in cases of drug …
Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of interaction with sodium channels. Lacosamide was first approved by the European Commission in August 2008 and was later...
Approved
Matched Synonyms: … (R)-LACOSAMIDE 1
Matched Description: … by the FDA in October 2008. ... As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated ... [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved …
Matched Mixtures name: … ELEPSİ 50 MG+100 MG TEDAVİYE BAŞLAMA PAKETİ, 42 ADET ... ELEPSİ 50 MG+100 MG TEDAVİYE BAŞLAMA PAKETİ, 42 ADET …
Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant to other osteoperosis therapies . Romosozumab prevents bone resorption and induces the formation of bone though it is associated...
Approved
Investigational
Matched Description: … Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal ... Romosozumab is marketed in the United States by Amgen under the brand name Evinity[L5921]. ... In a comparison study of post menopausal women with osteoporosis and a past fracture, romosozumab for …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 ML ... EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105MG/1.17ML …
Displaying drugs 201 - 225 of 14564 in total