Displaying drugs 201 - 225 of 9336 in total
Anileridine
Anileridine is a synthetic opioid and strong analgesic medication. It is a narcotic pain reliever used to treat moderate to severe pain. Narcotic analgesics act in the central nervous system (CNS) to relieve pain. Some of their side effects are also caused by actions in the CNS.
Approved
Illicit
Tretinoin
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Matched Description: … [A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism. …
Yohimbine
A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Approved
Investigational
Vet approved
Matched Description: … It is also alleged to be an aphrodisiac. …
Matched Categories: … Antidepressive Agents …
Matched Categories: … Antidepressive Agents …
Halcinonide
Halcinonide is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, and is distributed as a cream and ointment. Halcinonide is marketed under the brand name Halog® by Ranbaxy Laboratories Inc. Research suggests that clobetasol propionate demonstrates superior pharmacologic efficacy in the treatment of...
Approved
Investigational
Withdrawn
Matched Categories: … Corticosteroids, Very Potent (Group IV) …
Deoxycholic acid
Deoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that tissue. In April 2015, deoxycholic acid was approved by the FDA for the treatment submental fat to improve...
Approved
Matched Description: … It is marketed under the brand name Kybella by Kythera Biopharma and is the first pharmacological agent ... In April 2015, deoxycholic acid was approved by the FDA for the treatment submental fat to improve aesthetic …
Matched Categories: … Cytolytic Agent …
Matched Categories: … Cytolytic Agent …
Ubidecarenone
Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. The ubidecarenone is...
Approved
Investigational
Nutraceutical
Matched Description: … From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number ... [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant …
Trametinib
Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 inhibitor.[A258298,A258293] It was first approved by the FDA in May 2013 for the treatment of melanoma. It was later approved by Health Canada on July 18, 2013 and by the European Commission on June 30, 2014. Trametinib...
Approved
Matched Description: … Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) ... [A258298,A258293] It was first approved by the FDA in May 2013 for the treatment of melanoma. ... [L45583] Trametinib is currently approved to treat a variety of cancers with BRAF mutations, such as …
Anakinra
Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino acid residues. Unlike native human IL-1Ra, anakinra has an additional methionine residue at the amino terminus. This drug binds to the IL-1 receptor, competing with and inhibiting the activity of IL-1 alpha and beta. Anakinra is...
Approved
Investigational
Matched Description: … On November 14, 2001, it was approved by the FDA for the treatment of rheumatoid arthritis. ... It was later approved for the treatment of NOMID and DIRA on December 21, 2012, and December 18, 2020 ... Unlike native human IL-1Ra, anakinra has an additional methionine residue at the amino terminus. …
Iodixanol
Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.
Approved
Matched Description: … Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography …
Matched Categories: … Radiographic Contrast Agent …
Matched Categories: … Radiographic Contrast Agent …
Daunorubicin
A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Approved
Maprotiline
Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used...
Approved
Investigational
Matched Categories: … Antidepressive Agents ... Antidepressive Agents, Tetracyclic ... Antidepressive Agents, Second-Generation ... Antidepressive Agents Indicated for Depression …
Nalidixic acid
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched Description: … It is an inhibitor of the A subunit of bacterial DNA gyrase. ... Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum …
Palbociclib
Palbociclib is a piperazine pyridopyrimidine that acts in the cell cycle machinery. It is a second generation cyclin-dependent kinase inhibitor selected from a group of pyridopyrimidine compounds due to its favorable physical and pharmaceutical properties. Palbociclib was developed by Pfizer Inc after the discovery that identified the cyclin-dependent kinases as...
Approved
Investigational
Matched Description: … [L5867] It was originally FDA approved on March 2015 for the treatment of HR-positive, HER2-negative ... It is a second generation cyclin-dependent kinase inhibitor[A176798] selected from a group of pyridopyrimidine …
Cupric oxide
Cupric oxide, or copper (II) oxide, is an inorganic compound with the chemical formula CuO. Cupric oxide is used as a precursor in many copper-containing products such as wood preservatives and ceramics. Cupric oxide may be found in over-the-counter vitamin-mineral supplements as a source of DB09130. The mean daily dietary...
Approved
Matched Description: … Cupric oxide, or copper (II) oxide, is an inorganic compound with the chemical formula CuO. …
Xanthinol
Xanthinol is a very potent water-soluble derivative of niacin that can be found in diet supplements. It is also known as xanthinol nicotinate. Xaninthol is known to be a potent vasodilator that can easily pass through the cell membrane and once inside the cell it causes an increase in glucose...
Approved
Withdrawn
Matched Description: … [L1080] It was approved as a drug in 1998 in Canada and nowadays its status is cancelled post marketing ... increase in glucose metabolism resulting in an increased energy. ... potent vasodilator that can easily pass through the cell membrane and once inside the cell it causes an …
Dactylis glomerata pollen
Dactylis glomerata pollen is the pollen of the Dactylis glomerata plant. Dactylis glomerata pollen is mainly used in allergenic testing.
Approved
Lolium perenne pollen
Lolium perenne pollen is the pollen of the Lolium perenne plant. Lolium perenne pollen is mainly used in allergenic testing.
Approved
Anthoxanthum odoratum pollen
Anthoxanthum odoratum pollen is the pollen of the Anthoxanthum odoratum plant. Anthoxanthum odoratum pollen is mainly used in allergenic testing.
Approved
Gentian violet cation
A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
Approved
Cariprazine
Cariprazine is an atypical antipsychotic agent and a piperazine derivative that was first developed in Hungary. It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT1A receptors and as an antagonist at serotonin 5-HT2A receptors. Cariprazine has been investigated in a variety of psychiatric disorders,...
Approved
Investigational
Matched Description: … Cariprazine is an atypical antipsychotic agent and a piperazine derivative that was first developed in ... Cariprazine gained its first global approval in the US in September 2015 [A3941] and was later approved ... partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT1A receptors and as an …
Matched Categories: … Antidepressive Agents …
Matched Categories: … Antidepressive Agents …
Nicorandil
Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. It is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium...
Approved
Investigational
Matched Description: … It is not an approved drug by FDA. ... Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia …
Peramivir
Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B. The development of peramivir has been supported by the US Department of Health and Human Services as part of the government's effort to prepare for a flu pandemic. Being an influenza virus neuraminidase inhibitor, peramivir works by...
Approved
Investigational
Matched Description: … Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B. ... The injectable intravenous formulation of peramivir was approved by the FDA in September 2017 for the ... Being an influenza virus neuraminidase inhibitor, peramivir works by preventing new viruses from emerging …
Umbralisib
Marginal zone lymphoma is a rare, slowly progressing type of non-Hodgkin lymphoma initially treated with rituximab (an anti-CD20 drug), either alone or in combination with chemotherapy. Unfortunately, many patients experience a relapse or develop resistance to these drugs. Treatment options then become limited, and alternate treatments for the lymphoma are...
Approved
Investigational
Withdrawn
Matched Description: … lymphoma is a rare, slowly progressing type of non-Hodgkin lymphoma initially treated with [rituximab] (an ... It was marketed as Ukoniq by TG Therapeutics and has been approved for the treatment of relapsing and …
Lenalidomide
Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. It is a 4-amino-glutamyl analogue of thalidomide and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. However, lenalidomide is much safer and potent than thalidomide, with...
Approved
Matched Description: … imide group. ... [A228708] Available as oral capsules, lenalidomide is approved by the FDA and EU for the treatment of ... Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic …
Diltiazem
Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Description: … , and as an anti-anginal agent [L6289] for the management of cardiovascular conditions such as hypertension ... Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug ... Apart from its main FDA-approved indications, diltiazem has also been used for numerous off-label indications …
Displaying drugs 201 - 225 of 9336 in total