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Displaying drugs 2276 - 2300 of 15476 in total
One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Approved
Investigational
Vet approved
Matched Description: … combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and
Matched Categories: … sulfadiazine and tetroxoprim ... Sulfonamides and trimethoprim ... sulfadiazine and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Chronic kidney disease (CKD) is a progressive and irreversible disease that represents a significant burden for both the individual and healthcare system at large. Currently available treatments for end-stage renal disease are limited to dialysis and renal transplantation, with the former associated with significant costs and lower quality of life.[A225836,A225916]...
Approved
Investigational
Matched Description: … burden for both the individual and healthcare system at large. ... Chronic kidney disease (CKD) is a progressive and irreversible disease that represents a significant ... transplantation, with the former associated with significant costs and lower quality of life. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Darvadstrocel is a suspension of expanded human allogeneic adipose-derived mesenchymal stem cells extracted from the subdermal adipose tissue of healthy donors via liposuction. Darvadstrocel was first approved by the European Commission on March 23, 2018, under the brand name Alofisel. It is indicated for the treatment of complex perianal fistulas...
Approved
Experimental
Matched Description: … and enhance tissue repair in perianal fistulas. ... may be associated with complex presentations and symptoms. ... Perianal fistula is a common manifestation of Crohn’s disease and is often difficult to manage, as it …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Approved
Investigational
Vet approved
Matched Categories: … Piperazine and Derivatives ... Antiparasitic Products, Insecticides and Repellents …
Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of other aromatically bonded functional groups.
Approved
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Sulfadimethoxine is a sulfonamide antibiotic. Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved in some countries for use in humans. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic...
Approved
Vet approved
Withdrawn
Matched Description: … Sulfadimethoxine is approved in Russia for use in humans, including children, and has been successfully ... Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and
Matched Categories: … Sulfonamides and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.
Approved
Malathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment of head lice. Malathion is an irreversible cholinesterase inhibitor and has low human toxicity.
Approved
Investigational
Matched Description: … Malathion is an irreversible cholinesterase inhibitor and has low human toxicity. …
Matched Categories: … Scabicides, Insecticides and Repellents ... Antiparasitic Products, Insecticides and Repellents …
An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed)
Approved
Investigational
Vet approved
Matched Description: … It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. ... An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. …
Rapacuronium was withdrawn in 2001 in many countries due to risk of fatal bronchospasm.
Approved
Withdrawn
Nandrolone decanoate, also known as nandrolone caprinate, is an alkylated anabolic steroid indicated in the management of anemia of renal insufficiency and as an adjunct therapy in the treatment of senile and postmenopausal osteoporosis.[A233789,A233849,L32564,L9464] The process for creating esters of nandrolone was patented in Spain in 1959 and in 1960,...
Approved
Illicit
Matched Iupac: … (1S,3aS,3bR,9aR,9bS,11aS)-11a-methyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta …
Matched Description: … nandrolone and other esters. ... as an adjunct therapy in the treatment of senile and postmenopausal osteoporosis. ... caprinate, is an alkylated anabolic steroid indicated in the management of anemia of renal insufficiency and
Matched Categories: … Nandrolone and esters ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders and may be considered...
Approved
Matched Iupac: … 4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-(2-{6,6-dimethylbicyclo[3.1.1]heptan-2-yl}ethoxy)ethyl]morpholin …
Matched Description: … It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility ... disorders [A19697] and may be considered as effective first-lline therapy for patients with irritable …
Matched Categories: … Alimentary Tract and Metabolism ... Calcium-Regulating Hormones and Agents …
Colfosceril palmitate is a synthetic pulmonary surfactant administered in infants with respiratory distress syndrome. It was part of the first generation of commercially available artificial surfactants. It was developed by Burroughs Wellcome and it was FDA approved on August 6, 1990. Nowadays colfosceril palmitate is under the state of canceled...
Approved
Investigational
Withdrawn
Matched Description: … [T70] It was developed by Burroughs Wellcome and it was FDA approved on August 6, 1990. ... Colfosceril palmitate is a synthetic pulmonary surfactant administered in infants with respiratory distress …
Moxisylyte, denominated as thymoxamine in the UK, is a specific and orally active α1-adrenergic antagonist. According to the WHO, moxisylyte is approved since 1987 and in the same year, it acquired the denomination of orphan product by the FDA. This drug was developed by the Japanese company Fujirebio and also...
Approved
Investigational
Matched Iupac: … 4-[2-(dimethylamino)ethoxy]-2-methyl-5-(propan-2-yl)phenyl acetate …
Matched Description: … Moxisylyte, denominated as thymoxamine in the UK, is a specific and orally active α1-adrenergic antagonist ... [T45] According to the WHO, moxisylyte is approved since 1987[T91] and in the same year, it acquired ... [L1172] This drug was developed by the Japanese company Fujirebio and also by the American company Iolab …
Matched Categories: … Genito Urinary System and Sex Hormones …
Lycopene is a naturally occurring red carotenoid pigment that is responsible for red to pink colors seen in tomatoes, pink grapefruit, and other foods . Having a chemical formula of C40H56, lycopene is a tetraterpene assembled from eight isoprene units that are solely composed of carbon and hydrogen. Lycopene may...
Approved
Investigational
Matched Description: … red carotenoid pigment that is responsible for red to pink colors seen in tomatoes, pink grapefruit, and ... , lycopene is a tetraterpene assembled from eight isoprene units that are solely composed of carbon and ... classified as a non-provitamin A carotenoid pigment since it lacks a terminal beta-ionone ring [A27242] and
Diacetyl benzoyl lathyrol is an active ingredient in whitening creams. It is also reported to be a skin conditioning agent.
Approved
A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. It is used in commercial drug preparations to solubilize drugs for injection
Approved
Matched Description: … A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. …
Matched Categories: … Indicators and Reagents …
DL-dimyristoylphosphatidylglycerol is a phospholipid used in commercially available pharmaceutical preparations to solubilize drugs for injection.
Approved
Squalene is originally obtained from shark liver oil. It is a natural 30-carbon isoprenoid compound and intermediate metabolite in the synthesis of cholesterol. It is not susceptible to lipid peroxidation and provides skin protection. It is ubiquitously distributed in human tissues where it is transported in serum generally in association...
Approved
Vet approved
Matched Description: … It is not susceptible to lipid peroxidation and provides skin protection. ... It is a natural 30-carbon isoprenoid compound and intermediate metabolite in the synthesis of cholesterol …
Steviolbioside has been used in trials studying the treatment of HIV-1 Infection.
Approved
Investigational
Matched Categories: … Diet, Food, and Nutrition …
Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
Approved
Investigational
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Magnesium silicate is a compound of magnesium oxide and silicon. It is the magnesium salt of silicic acid containing an unspecified amount of water. The molecular formula can be expressed more clearly as MgSiO3.xH2O. It is known as talc and it presents many uses in the cosmetic industry, food industry...
Approved
Matched Description: … [T186] It is known as talc and it presents many uses in the cosmetic industry, food industry and pharmaceutical ... Magnesium silicate is a compound of magnesium oxide and silicon. …
Matched Categories: … Alimentary Tract and Metabolism ... Aluminum and magnesium containing antacids …
Estradiol Dienanthate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol benzoate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-7-(heptanoyloxy)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[ …
Matched Description: … a chance to enter systemic circulation and exert its estrogenic effects [A12102]. ... Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex ... same downstream effects within the body through binding to the Estrogen Receptor (ER) including ERα and
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Lutein is an xanthophyll and one of 600 known naturally occurring carotenoids. Lutein is synthesized only by plants and like other xanthophylls is found in high quantities in green leafy vegetables such as spinach, kale and yellow carrots. In green plants, xanthophylls act to modulate light energy and serve as...
Approved
Investigational
Nutraceutical
Matched Description: … leafy vegetables such as spinach, kale and yellow carrots. ... Lutein is an xanthophyll and one of 600 known naturally occurring carotenoids. ... Lutein is synthesized only by plants and like other xanthophylls is found in high quantities in green …
Displaying drugs 2276 - 2300 of 15476 in total