Displaying drugs 2301 - 2325 of 8249 in total
Etavopivat
Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
Investigational
Matched Synonyms: … 1-propanone, 1-(5-((2,3-dihydro-1,4-dioxino(2,3-b)pyridin-7-yl)sulfonyl)-3,4,5,6-tetrahydropyrrolo(3,4 ... -c)pyrrol-2(1h)-yl)-3-hydroxy-2-phenyl-, (2s)- …
Matched Iupac: … (2S)-1-(5-{2H,3H-[1,4]dioxino[2,3-b]pyridine-7-sulfonyl}-1H,2H,3H,4H,5H,6H-pyrrolo[3,4-c]pyrrol-2-yl) ... -3-hydroxy-2-phenylpropan-1-one …
Matched Iupac: … (2S)-1-(5-{2H,3H-[1,4]dioxino[2,3-b]pyridine-7-sulfonyl}-1H,2H,3H,4H,5H,6H-pyrrolo[3,4-c]pyrrol-2-yl) ... -3-hydroxy-2-phenylpropan-1-one …
Irpagratinib
Irpagratinib (ABSK011) is a highly selective inhibitor of fibroblast growth factor receptor (FGFR) 4.
Investigational
Matched Synonyms: … )pyrido[3,4-d]pyrimidin-2-yl]amino]tetrahydro-2H-pyran-4-yl]- ... N-[(3S,4S)-3-[[6-(2,6-Difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methyl-1-azetidinyl)pyrido[3,4-d]pyrimidin ... -2-yl]amino]tetrahydro-2H-pyran-4-yl]-2-propenamide …
Matched Iupac: … N-[(3S,4S)-3-{[6-(2,6-difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methylazetidin-1-yl)pyrido[3,4-d]pyrimidin ... -2-yl]amino}oxan-4-yl]prop-2-enamide …
Matched Description: … Irpagratinib (ABSK011) is a highly selective inhibitor of fibroblast growth factor receptor (FGFR) 4. …
Matched Iupac: … N-[(3S,4S)-3-{[6-(2,6-difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methylazetidin-1-yl)pyrido[3,4-d]pyrimidin ... -2-yl]amino}oxan-4-yl]prop-2-enamide …
Matched Description: … Irpagratinib (ABSK011) is a highly selective inhibitor of fibroblast growth factor receptor (FGFR) 4. …
LGD-3303
An androgen receptor modulator.
Experimental
Matched Synonyms: … 9-Chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H-pyrrolo(3,2-F)quinolin-7(6H)-one …
Matched Iupac: … 9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H,6H,7H-pyrrolo[3,2-f]quinolin-7-one …
Matched Iupac: … 9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H,6H,7H-pyrrolo[3,2-f]quinolin-7-one …
Resveratrol
Resveratrol (3,5,4'-trihydroxystilbene) is a polyphenolic phytoalexin. It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. It exists as cis-(Z) and trans-(E) isomers. The trans- form can undergo isomerisation to the cis- form when heated or exposed to ultraviolet...
Investigational
Matched Synonyms: … 3,4',5-trihydroxystilbene ... 3,4',5-trihydroxy-trans-stilbene ... (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol …
Matched Iupac: … 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol …
Matched Iupac: … 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol …
7.beta.-hydroxycholesteryl-3-oleate
Investigational
Matched Synonyms: … Cholest-5-ene-3,7-diol, 3-(9z)-9-octadecenoate, (3.beta.,7.beta.)- ... -hydroxycholesterol 3-oleate ... -hydroxycholesteryl 3-oleate …
Matched Name: … -hydroxycholesteryl-3-oleate …
Matched Iupac: … ,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl (9Z)-octadec-9-enoate ... (1R,3aS,3bS,4R,7S,9aR,9bS,11aR)-4-hydroxy-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH …
Matched Name: … -hydroxycholesteryl-3-oleate …
Matched Iupac: … ,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl (9Z)-octadec-9-enoate ... (1R,3aS,3bS,4R,7S,9aR,9bS,11aR)-4-hydroxy-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH …
Deulinoleate ethyl
Investigational
Matched Synonyms: … 9-cis, 12-cis-11,11-d2-linoleic acid ethyl ester ... 9-cis,12-cis-11,11-D2-linoleic acid ethyl ester …
Soraprazan
Investigational
Matched Synonyms: … (7r,8r,9r)-7-(2-methoxyethoxy)-2,3-dimethyl-9-phenyl-7,8,9,10-tetrahydroimidazo(1,2-h)(1,7)naphtyridin …
Matched Iupac: … (7R,8R,9R)-7-(2-methoxyethoxy)-2,3-dimethyl-9-phenyl-7H,8H,9H,10H-imidazo[1,2-h]1,7-naphthyridin-8-ol …
Matched Iupac: … (7R,8R,9R)-7-(2-methoxyethoxy)-2,3-dimethyl-9-phenyl-7H,8H,9H,10H-imidazo[1,2-h]1,7-naphthyridin-8-ol …
Pristimerin
Pristimerin is a quinone methide triterpenoid researched for its anti-cancer potential.
Investigational
Matched Synonyms: … (9.beta.,13.alpha.,14.beta.,20.alpha.)-3-hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7 ... (9.beta.,13.alpha.,14.beta.,20.alpha ... 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9,13-dimethyl-2-oxo-, methyl ester, …
Valine-valine-ganciclovir
Investigational
Matched Synonyms: … L-valine, l-valyl-, 2-((2-amino-1,6-dihydro-6-oxo-9h-purin-9-yl)methoxy)-3-hydroxypropyl ester …
Matched Iupac: … (2R)-2-[(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)methoxy]-3-hydroxypropyl (2S)-2-[(2S)-2-amino-3-methylbutanamido ... ]-3-methylbutanoate …
Matched Iupac: … (2R)-2-[(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)methoxy]-3-hydroxypropyl (2S)-2-[(2S)-2-amino-3-methylbutanamido ... ]-3-methylbutanoate …
Idronoxil
Idronoxil is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called signal transduction inhibitors.
Investigational
Matched Synonyms: … (+/-)-cis-3-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-3,4-dihydro-2H-cromen-7-ol ... 3-(4-hydroxyphenyl)-2H-chromen-7-ol …
Matched Iupac: … 3-(4-hydroxyphenyl)-2H-chromen-7-ol …
Matched Iupac: … 3-(4-hydroxyphenyl)-2H-chromen-7-ol …
VPO-227
Investigational
Matched Synonyms: … (+-)-9-(5-bromofuran-2-yl)-12,14-dimethyl-13,15-dioxo-17-phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16 ... ]heptadeca-2(7),3,5,10,16-pentaene-4-carboxylic acid …
Matched Iupac: … 9-(5-bromofuran-2-yl)-12,14-dimethyl-13,15-dioxo-17-phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.0^{2,7 ... }.0^{11,16}]heptadeca-2,4,6,10,16-pentaene-4-carboxylic acid …
Matched Iupac: … 9-(5-bromofuran-2-yl)-12,14-dimethyl-13,15-dioxo-17-phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.0^{2,7 ... }.0^{11,16}]heptadeca-2,4,6,10,16-pentaene-4-carboxylic acid …
6-hydroxydopa quinone
Experimental
Matched Synonyms: … 6-Hydroxyphenylalanine-3,4-dione ... (S)-α-amino-4-hydroxy-3,6-dioxo-1,4-cyclohexadiene-1-propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3,6-dioxocyclohexa-1,4-dien-1-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3,6-dioxocyclohexa-1,4-dien-1-yl)propanoic acid …
RGX-121
RGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the central nervous system.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus (AAV) vector of serotype 9 expressing human iduronate …
Ongericimab
Ongericimab is under investigation in clinical trial NCT05325203 (A Study to Evaluate the Efficacy and Safety of JS002 in Patients With Heterozygous Familial Hypercholesterolemia (Hefh).).
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(neural apoptosis-regulated convertase 1) (human monoclonal js002 .gamma.4-chain ... Immunoglobulin g4-kappa, anti-(homo sapienspcsk9 (proprotein convertase subtilisin/kexin type 9, neural ... apoptosis-regulated convertase 1, narc1, narc-1, proprotein convertase 9, pc9)), humanized monoclonal …
Tenofovir amibufenamide
Investigational
Matched Synonyms: … Alanine, n-((s)-(((1r)-2-(6-amino-9h-purin-9-yl)-1-methylethoxy)methyl)phenoxyphosphinyl)-2-methyl-, …
SB 224289
SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.
Investigational
Matched Synonyms: … (1'-methyl-6,7-dihydro-5h-spiro(furo(2,3-f)indole-3,4'-piperidin)-5-yl)(2'-methyl-4'-(5-methyl-1,2,4- ... f)indole-3,4'-piperidine)-5-yl)methanone ... -f)indole-3,4'-piperidin)-5(2h)-yl)methanone …
Matched Iupac: … 1'-methyl-5-[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carbonyl]-2,5,6,7-tetrahydrospiro ... [furo[2,3-f]indole-3,4'-piperidine] …
Matched Description: … SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.[A253122] …
Matched Iupac: … 1'-methyl-5-[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carbonyl]-2,5,6,7-tetrahydrospiro ... [furo[2,3-f]indole-3,4'-piperidine] …
Matched Description: … SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.[A253122] …
Minnelide free acid
Investigational
Matched Synonyms: … Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl …
Ochromycinone
Ochromycinone is under investigation in clinical trial NCT01047943 (STA-21 Topical Efficacy on Psoriasis).
Investigational
Matched Synonyms: … Benz(a)anthracene-1,7,12(2h)-trione, 3,4-dihydro-8-hydroxy-3-methyl-, (s)- ... (3s)-3.beta.-methyl-8-hydroxy-1,2,3,4,7,12-hexahydrobenzo(a)anthracene-1,7,12-trione …
Matched Iupac: … (3S)-8-hydroxy-3-methyl-1,2,3,4,7,12-hexahydrotetraphene-1,7,12-trione …
Matched Iupac: … (3S)-8-hydroxy-3-methyl-1,2,3,4,7,12-hexahydrotetraphene-1,7,12-trione …
Pinometostat
Pinometostat has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others.
Investigational
Matched Synonyms: … 9H-PURIN-6-AMINE, 9-(5-DEOXY-5-((CIS-3-(2-(6-(1,1-DIMETHYLETHYL)-1H-BENZIMIDAZOL-2-YL)ETHYL)CYCLOBUTYL …
Matched Iupac: … (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-{[(propan-2-yl)[(1r,3s)-3-[2-(6-tert-butyl-1H-1,3-benzodiazol ... -2-yl)ethyl]cyclobutyl]amino]methyl}oxolane-3,4-diol …
Matched Iupac: … (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-{[(propan-2-yl)[(1r,3s)-3-[2-(6-tert-butyl-1H-1,3-benzodiazol ... -2-yl)ethyl]cyclobutyl]amino]methyl}oxolane-3,4-diol …
Rilzabrutinib
Rilzabrutinib is an oral, reversible covalent inhibitor of Bruton's tyrosine kinase being investigated for the treatment of immune disorders, such as immune thrombocytopenic purpura.[A259073, A259078]
Investigational
Matched Synonyms: … (e/z)-(r)-2-(3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1h-pyrazolo(3,4-d)pyrimidin-1-yl)piperidine-1-carbonyl ... 1-piperidinepropanenitrile, 3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1h-pyrazolo(3,4-d)pyrimidin-1-yl) ... )-4-methyl-4-(4-(oxetan-3-yl)piperazin-1-yl)pent-2-enenitrile …
Matched Iupac: … (2E)-2-[(E)-(3R)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine- ... 1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile …
Matched Iupac: … (2E)-2-[(E)-(3R)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine- ... 1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile …
1,3-bis-([3-[3-[3-(4-{3-[3-nitro-5-(galactopyranosyloxy)-benzoylamino]-propyl}-piperazin-1-yl)-propylamino-3,4-dioxo-cyclobutenyl]-amino-propoxy-ethoxy-ethoxy]-propyl-]amino-carbonyloxy)-2-amino-propane
Experimental
Matched Name: … 1,3-bis-([3-[3-[3-(4-{3-[3-nitro-5-(galactopyranosyloxy)-benzoylamino]-propyl}-piperazin-1-yl)-propylamino ... -3,4-dioxo-cyclobutenyl]-amino-propoxy-ethoxy-ethoxy]-propyl-]amino-carbonyloxy)-2-amino-propane …
Matched Iupac: … (Z)-N-[3-(4-{3-[(2-{14-[(E)-[(2-amino-3-{[(E)-{3-[2-(2-{3-[(2-{[3-(4-{3-[(Z)-[hydroxy(3-nitro-5-{[(2R ... -dioxocyclobut-1-en-1-yl)amino]propyl}piperazin-1-yl)propyl]-3-nitro-5-{[3,4,5-trihydroxy-6-(hydroxymethyl ... trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]amino]propyl}piperazin-1-yl)propyl]amino}-3,4 ... -C-hydroxycarbonimidoyl]oxy}propoxy)(hydroxy)methylidene]amino]-5,8,11-trioxa-1-azatetradecan-1-yl}-3,4 …
Matched Iupac: … (Z)-N-[3-(4-{3-[(2-{14-[(E)-[(2-amino-3-{[(E)-{3-[2-(2-{3-[(2-{[3-(4-{3-[(Z)-[hydroxy(3-nitro-5-{[(2R ... -dioxocyclobut-1-en-1-yl)amino]propyl}piperazin-1-yl)propyl]-3-nitro-5-{[3,4,5-trihydroxy-6-(hydroxymethyl ... trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]amino]propyl}piperazin-1-yl)propyl]amino}-3,4 ... -C-hydroxycarbonimidoyl]oxy}propoxy)(hydroxy)methylidene]amino]-5,8,11-trioxa-1-azatetradecan-1-yl}-3,4 …
Dihydrouridine
Investigational
Matched Synonyms: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione …
ESK981
Investigational
Matched Synonyms: … 4h-indazolo(5,4-a)pyrrolo(3,4-c)carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl) ... -8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1) …
Matched Iupac: … ^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4(9),5,7,11(15),17,20-octaen-14-one; 4-methylbenzene-1 ... 19-methyl-3-(2-methylpropyl)-7-[(pyrimidin-2-yl)amino]-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … ^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4(9),5,7,11(15),17,20-octaen-14-one; 4-methylbenzene-1 ... 19-methyl-3-(2-methylpropyl)-7-[(pyrimidin-2-yl)amino]-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Certepetide
Investigational
Matched Synonyms: … Ac-Cys-Arg-Gly-Asp-Lys-Gly-Pro-Asp-Cys-NH2 cyclic (1→9)-disulfide ... , N-acetyl-L-cysteinyl-L-arginylglycyl-L-α-aspartyl-L-lysylglycyl-L-prolyl-L-α-aspartyl-, cyclic (1→9) ... N-Acetyl-L-cysteinyl-L-arginylglycyl-L-α-aspartyl-L-lysylglycyl-L-prolyl-L-α-aspartyl-L-cysteinamide, cyclic (1→9) …
Ukrain cation
Investigational
Matched Synonyms: … (1,3)benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridinium, 13,13',13''-(phosphinothioylidynetris(imino ... Chelidoninium, 5,5',5''-(phosphinothioylidynetris(imino-2,1-ethanediyl))tris(5-methyl- ... -2,1-ethanediyl))tris(5b,6,7,12b,13,14-hexahydro-6-hydroxy-13-methyl-, (5br,5'br,5''br,6s,6's,6''s,12bs …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Heterocyclic Compounds with 4 or More Rings …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Heterocyclic Compounds with 4 or More Rings …
Displaying drugs 2301 - 2325 of 8249 in total