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Displaying drugs 2351 - 2375 of 2437 in total
Istaroxime
Investigational
Matched Categories: … Sodium-Potassium-Exchanging ATPase, antagonists & inhibitors …
Limaprost
Limaprost (as Limaprost alfadex; CAS number 88852-12-4) is an oral prostaglandin E1 analog. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostaglandins have a wide variety of actions, including,...
Investigational
Matched Categories: … Platelet Aggregation Inhibitors Excl. Heparin …
Firocoxib
Firocoxib is a cycooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug. It currently approved for veterinary use in dogs and horses under the brand names Equioxx and Previcox. Firocoxib was the first COX-2 inhibitor approved by the U.S. Food and Drug Administration for horses. Firocoxib is not intended or approved for use...
Experimental
Vet approved
Matched Categories: … Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Masitinib
Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.
Investigational
Vet approved
Matched Categories: … Protein Kinase Inhibitors …
ONO-8539
ONO-8539 is under investigation in clinical trial NCT01707901 (A Study of the Effect of ONO-8539 on Oesophageal Pain Hypersensitivity in Patients With Non-erosive Reflux Disease).
Investigational
Matched Categories: … Receptors, Prostaglandin E, EP1 Subtype, antagonists & inhibitors …
Chelerythrine
A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.
Investigational
Matched Categories: … Protein Kinase C, antagonists & inhibitors …
Vinpocetine
Vinpocetine has been investigated for the treatment of Epilepsy.
Investigational
Matched Categories: … Enzyme Inhibitors ... Phosphodiesterase Inhibitors …
RI 624
RI 624 is a novel humanized monoclonal antibody that blocks nerve growth factor (NGF), a key mediator of acute and chronic pain. RI 624 is being developed by Rinat and is currently in Phase I clinical trials.
Investigational
Matched Categories: … Receptor, Nerve Growth Factor, antagonists & inhibitors …
Lufenuron
Lufenuron is used in veterinary for the control of flea.
Experimental
Vet approved
Matched Categories: … Chitin, antagonists & inhibitors …
Bombesin
Bombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and Healthy Volunteers).
Investigational
Matched Categories: … Bombesin, antagonists & inhibitors …
Fibrinolysin
Fibrinolysin consists of two polypeptide chains, one light and one heavy, linked by a disulfide bond. The light chain has a molecular weight of approximately 27,000 Da and contains the active center of Fibrinolysin; the heavy chain has a molecular weight of approximately 57,000 Da. Fibrinolysin is used as a...
Investigational
Matched Categories: … Fibrinolysin, antagonists & inhibitors …
N-Ethylmaleimide
A sulfhydryl reagent that is widely used in experimental biochemical studies. [PubChem]
Experimental
Matched Categories: … Enzyme Inhibitors …
Oglufanide
Oglufanide is a synthetic dipeptide immunomodulator in development for the treatment of chronic hepatitis C viral infection. Oglufanide was originally developed to treat severe infectious disease in Russia (where it is a registered pharmaceutical), and was extensively studied in cancer clinical trials in the United States before being acquired by...
Investigational
Matched Categories: … Growth Inhibitors …
Indirubin
Indirubin is under investigation in clinical trial NCT01735864 (Dosage Determination Trial for Indigo Naturalis Extract in Oil Ointment).
Investigational
Matched Categories: … Protein Kinase Inhibitors …
Pivhydrazine
Pivhydrazine, also known as pivazide, is a member of the hydrazine family with irreversible and non-selective inhibitory activity against monoamine oxidases. In 1960, it was widely used as an antidepressant agent but it is now discontinued.
Withdrawn
Matched Categories: … Monoamine Oxidase Inhibitors …
Buthionine sulfoximine
Buthionine sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin).
Investigational
Matched Categories: … Enzyme Inhibitors …
Sparfosic acid
Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen atom. This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein.
Experimental
Matched Categories: … Enzyme Inhibitors …
Sulfobromophthalein
Sulfobromophthalein or otherwise called bromsulphthalein is used as a test of liver function in humans .
Experimental
Matched Categories: … NTCP Inhibitors …
Afelimomab
Afelimomab (also known as Fab 2 or MAK 195F) is an anti-TNF-α monoclonal antibody. Administration of 195F reduces the concentration of interleukin-6 in patients with sepsis.
Investigational
Matched Categories: … Tumor necrosis factor alpha (TNF-alpha) inhibitors …
Proscillaridin
Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin, based on evidence of the drug potently disrupting topoisomerase I and II activity at nanomolar drug concentrations and triggering cell...
Experimental
Matched Categories: … Enzyme Inhibitors …
6-O-benzylguanine
6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others.
Investigational
Matched Categories: … Enzyme Inhibitors …
Telotristat
A tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat.
Experimental
Matched Categories: … Tryptophan Hydroxylase Inhibitors …
Clevudine
Investigational
Matched Categories: … Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Displaying drugs 2351 - 2375 of 2437 in total