Displaying drugs 2376 - 2400 of 3060 in total
13-cis-12-(3'-Carboxyphenyl)retinoic acid
Experimental
Matched Name: … 13-cis-12-(3'-Carboxyphenyl)retinoic acid …
Matched Iupac: … 5E,7E)-1-carboxy-2,6-dimethyl-8-(2,6,6-trimethylcyclohex-1-en-1-yl)octa-1,3,5,7-tetraen-3-yl]benzoic acid …
Matched Iupac: … 5E,7E)-1-carboxy-2,6-dimethyl-8-(2,6,6-trimethylcyclohex-1-en-1-yl)octa-1,3,5,7-tetraen-3-yl]benzoic acid …
Linerixibat
GSK2330672 has been investigated for the treatment of Diabetes Mellitus, Type 2.
Investigational
Matched Synonyms: … 1,1-DIOXO-5-PHENYL-2,3,4,5-TETRAHYDRO- 1H-1.LAMBDA.6,4-BENZOTHIAZEPIN-8-YL)METHYL)AMINO)PENTANEDIOIC ACID ... PENTANEDIOIC ACID, 3-((((3R,5R)-3-BUTYL-3-ETHYL-2,3,4,5-TETRAHYDRO-7-METHOXY-1,1-DIOXIDO-5-PHENYL-1,4 …
Matched Iupac: … methoxy-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,4-benzothiazepin-8-yl]methyl}amino)pentanedioic acid …
Matched Categories: … Sulfur Compounds …
Matched Iupac: … methoxy-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,4-benzothiazepin-8-yl]methyl}amino)pentanedioic acid …
Matched Categories: … Sulfur Compounds …
JS-K
Investigational
Matched Synonyms: … 1-piperazinecarboxylic acid, 4-((2,4-dinitrophenoxy)-nno-azoxy)-, ethyl ester ... 1-piperazinecarboxylic acid, 4-(2-(2,4-dinitrophenoxy)-1-oxidodiazenyl)-, ethyl ester …
Benazeprilat
Experimental
Matched Synonyms: … (3S)-3-(((1S)-1-Carboxy-3-phenylpropyl)amino)-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid …
Matched Iupac: … 2S)-2-{[(3S)-1-(carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]amino}-4-phenylbutanoic acid …
Matched Iupac: … 2S)-2-{[(3S)-1-(carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]amino}-4-phenylbutanoic acid …
AGF-94
Investigational
Matched Synonyms: … (2-amino-4-oxo-4,7-dihydro-3 h-pyrrolo(2,3-d)pyrimidin-6-yl)propyl)thiophene-2-carbonyl)-l-glutamic acid …
Matched Iupac: … (3-{2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-6-yl}propyl)thiophen-2-yl]formamido}pentanedioic acid …
Matched Iupac: … (3-{2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-6-yl}propyl)thiophen-2-yl]formamido}pentanedioic acid …
Hydromorphone
Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Description: … the absence of a double bond between the carbon 7 and 8. ... hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and ... Due to these modifications, it presents a very high potency and comparable side effect profile to the …
Matched Salts name: … Hydromorphone sulfate …
Matched Categories: … hydromorphone and naloxone ... hydromorphone and antispasmodics …
Matched Products: … Bar-hydromorphone CR …
Matched Salts name: … Hydromorphone sulfate …
Matched Categories: … hydromorphone and naloxone ... hydromorphone and antispasmodics …
Matched Products: … Bar-hydromorphone CR …
Pemlimogene merolisbac
Pemlimogene merolisbac is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study of JNJ-64041757, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Nivolumab Versus Nivolumab Monotherapy in Participants With Advanced Adenocarcinoma of the Lung).
Investigational
Matched Synonyms: … of the lm acta protein (actan100), 5 tandem copies of a 21 amino acid fr ... monocytogenes (lm .delta.acta/.delta.inlb) expressing a fusion protein comprising the n-terminal 100 amino acids …
Matched Description: … Pemlimogene merolisbac is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study …
Matched Description: … Pemlimogene merolisbac is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study …
Verapamil
Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced ... drugs like [diltiazem] and [flunarizine], but is chemically unrelated to other cardioactive medications ... [L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer …
Matched Mixtures name: … Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Verapamil and analogues ... trandolapril and verapamil ... Calcium Channel Blockers ... Calcium Channel Blockers (Nondihydropyridine) …
Matched Products: … VERAPAMIL ACIS 240MG RETAR …
Matched Mixtures name: … Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Verapamil and analogues ... trandolapril and verapamil ... Calcium Channel Blockers ... Calcium Channel Blockers (Nondihydropyridine) …
Matched Products: … VERAPAMIL ACIS 240MG RETAR …
Immucin
Investigational
Matched Synonyms: … Synthetic Signal Peptide Of Human Mucin-1 (Amino Acids 1-21) …
Zinc phenolsulfonate
Approved
Experimental
Matched Synonyms: … p-hydroxybenzenesulfonic acid zinc salt …
Matched Iupac: … zinc(2+) bis(4-hydroxybenzene-1-sulfonate) …
Matched Iupac: … zinc(2+) bis(4-hydroxybenzene-1-sulfonate) …
Berdazimer
Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate entity. Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral cutaneous...
Approved
Matched Synonyms: … Silsesquioxanes, 3-(2-hydroxy-1-methyl-2-nitrosohydrazinyl)propyl 3-(methylamino)propyl, polymers with silicic acid …
Matched Description: … skin discoloration, and fear and anxiety in the pediatric population. ... molluscum contagiosum, a viral cutaneous infection mainly affecting children, sexually active adults, and ... pediatric molluscum contagiosum, and it is the first drug to be approved for this condition. …
Matched Salts name: … Berdazimer sodium …
Matched Description: … skin discoloration, and fear and anxiety in the pediatric population. ... molluscum contagiosum, a viral cutaneous infection mainly affecting children, sexually active adults, and ... pediatric molluscum contagiosum, and it is the first drug to be approved for this condition. …
Matched Salts name: … Berdazimer sodium …
Pyrazinamide
A pyrazine that is used therapeutically as an antitubercular agent.
Approved
Investigational
Matched Synonyms: … Pyrazinoic acid amide …
Matched Categories: … rifampicin, pyrazinamide and isoniazid ... rifampicin, pyrazinamide, ethambutol and isoniazid …
Matched Categories: … rifampicin, pyrazinamide and isoniazid ... rifampicin, pyrazinamide, ethambutol and isoniazid …
Pristimerin
Pristimerin is a quinone methide triterpenoid researched for its anti-cancer potential.
Investigational
Matched Synonyms: … .)-3-hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid ... 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9,13-dimethyl-2-oxo-, methyl ester, …
Sunobinop
Sunobinop is under investigation in clinical trial NCT04035200 (Safety, Tolerability and Efficacy Study of V117957 in Subjects With Insomnia Associated With Alcohol Cessation).
Investigational
Matched Synonyms: … 2-quinoxalinecarboxylic acid, 4-((3-endo)-9-(3-exo)-bicyclo(3.3.1)non-3-yl-9-azabicyclo(3.3.1)non-3-yl ... 3'r,5s,5's)-9'-aza(3,9'- bi(bicyclo(3.3.1)nonan))-3'-yl)-3-oxo-3,4- dihydroquinoxaline-2-carboxylic acid …
Matched Description: … Sunobinop is under investigation in clinical trial NCT04035200 (Safety, Tolerability and Efficacy Study …
Matched Description: … Sunobinop is under investigation in clinical trial NCT04035200 (Safety, Tolerability and Efficacy Study …
Opelconazole
Investigational
Matched Synonyms: … D-threo-pentitol, 2,5-anhydro-1,3,4-trideoxy-2-c-(2,4-difluorophenyl)-4-((4-(4-(4-(((4-fluorophenyl)amino …
Empagliflozin
Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for the reabsorption of glucose in the kidney. It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus. The first known inhibitor...
Approved
Matched Synonyms: … (1S)-1,5-anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucitol …
Matched Description: … Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily ... [L13688] The first known inhibitor of SGLTs, phlorizin, was isolated from the bark of apple trees ... led to the FDA approval of [canagliflozin] in 2013 and both [dapagliflozin] and empagliflozin in 2014 …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors ... Alimentary Tract and Metabolism ... metformin and empagliflozin ... linagliptin and empagliflozin …
Matched Description: … Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily ... [L13688] The first known inhibitor of SGLTs, phlorizin, was isolated from the bark of apple trees ... led to the FDA approval of [canagliflozin] in 2013 and both [dapagliflozin] and empagliflozin in 2014 …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors ... Alimentary Tract and Metabolism ... metformin and empagliflozin ... linagliptin and empagliflozin …
Methylergometrine
A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Approved
Matched Synonyms: … D-lysergic acid 1-butanolamide …
Matched Categories: … Ergot Alkaloids and Derivatives ... methylergometrine and oxytocin ... Genito Urinary System and Sex Hormones …
Matched Categories: … Ergot Alkaloids and Derivatives ... methylergometrine and oxytocin ... Genito Urinary System and Sex Hormones …
(2R,4S)-2-[(1R)-1-{[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
Experimental
Matched Synonyms: … 2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Matched Name: … 2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Matched Iupac: … -[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Matched Name: … 2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Matched Iupac: … -[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Pixofisiran
Investigational
Matched Synonyms: … Cotsiranib tgf-.beta.1 si-rna free acid component ... Stp-705 component tgf-.beta.1 si-rna free acid ... Tgf-.beta.1 si-rna free acid component of cotsiranib …
Matched Salts name: … Pixofisiran sodium …
Matched Salts name: … Pixofisiran sodium …
Oxacillin
An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Approved
Investigational
Matched Synonyms: … 6β-(5-methyl-3-phenylisoxazol-4-yl)penicillanic acid ... 5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Salts name: … Oxacillin sodium ... Oxacillin sodium monohydrate …
Matched Categories: … Sulfur Compounds …
Matched Iupac: … dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Salts name: … Oxacillin sodium ... Oxacillin sodium monohydrate …
Matched Categories: … Sulfur Compounds …
Reserpine
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool,...
Approved
Investigational
Withdrawn
Matched Synonyms: … 16beta,17alpha,18beta,20alpha)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid …
Matched Description: … An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. ... serotonin from central and peripheral axon terminals. ... inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and …
Matched Categories: … reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …
Matched Description: … An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. ... serotonin from central and peripheral axon terminals. ... inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and …
Matched Categories: … reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …
VPO-227
Investigational
Matched Synonyms: … phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-4-carboxylic acid …
Matched Iupac: … -8-oxa-1,12,14-triazatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-2,4,6,10,16-pentaene-4-carboxylic acid …
Matched Iupac: … -8-oxa-1,12,14-triazatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-2,4,6,10,16-pentaene-4-carboxylic acid …
Carbenicillin
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Matched Synonyms: … N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid ... -6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … )-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Matched Categories: … Sulfur Compounds …
Matched Iupac: … )-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Matched Categories: … Sulfur Compounds …
Pirmitegravir
Pirmitegravir is under investigation in clinical trial NCT05869643 (A Clinical Trial of STP0404 in Treatment-naïve Adults With HIV-1 Infection).
Investigational
Matched Synonyms: … 1H-Pyrrolo[2,3-b]pyridine-5-acetic acid, 4-(4-chlorophenyl)-α-(1,1-dimethylethoxy)-2,3,6-trimethyl-1- ... dimethylethoxy)-2,3,6-trimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridine-5-acetic acid …
4,5-Dihydroxy-Tetrahydro-Pyran-2-Carboxylic Acid
Experimental
Matched Name: … 4,5-Dihydroxy-Tetrahydro-Pyran-2-Carboxylic Acid …
Matched Iupac: … (2S,4S,5S)-4,5-dihydroxyoxane-2-carboxylic acid …
Matched Iupac: … (2S,4S,5S)-4,5-dihydroxyoxane-2-carboxylic acid …
Displaying drugs 2376 - 2400 of 3060 in total