Cytochrome P450 2C18

BE0003611ProteinHumansCYP2C18

A cytochrome P450 monooxygenase involved in retinoid metabolism. It is acted on by 31 drugs in DrugBank.

Gene name
CYP2C18
UniProtKB entry
P33260Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
490 residues · 55,710 Da
Also known as
1.14.14.1 · CYPIIC18 · Cytochrome P450-6b/29c

Resolves to

Protein
UniProtP33260UniProt nameCP2CI_HUMAN
Gene
HGNCHGNC:2620NCBI Gene1562GeneCardsCYP2C18
Pharmacology
IUPHAR/GtoPdb1327KEGGhsa:1562
Structure
PDB2CIKPDB2H6P
Drugs

What you can answer from here — as of September 07, 2019

31DrugsApproved to experimental, with action, bond type and pharmacological action
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21Metabolic reactionsDrug transformations it catalyses, substrate to product
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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52+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cytochrome P450 2C18, how selective are they, and which programs against it are still in active trials?

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