Penicillin-binding protein 1b

BE0004335ProteinStreptococcus pneumoniae (strain ATCC BAA-255 / R6)pbp1b

Penicillin-binding protein 1b (Streptococcus pneumoniae (strain ATCC BAA-255 / R6)) is a protein target in DrugBank. It is acted on by 16 drugs in DrugBank.

Gene name
pbp1b
UniProtKB entry
Q7CRA4TrEMBL
Residues / weight
821 residues · 89,480 Da

Resolves to

Protein
UniProtQ7CRA4UniProt nameQ7CRA4_STRR6
Gene
NCBI Gene934893GenBank15457529
Pharmacology
KEGGspr:spr1909
Structure
PDB2UWXPDB2XD1PDB2XD5
Drugs

What you can answer from here — as of September 07, 2019

16DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Penicillin-binding protein 1b, how selective are they, and which programs against it are still in active trials?

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