Accession Number

The glyceryl esters of a fatty acid, or of a mixture of fatty acids. They are generally odorless, colorless, and tasteless if pure, but they may be flavored according to origin. Fats are insoluble in water, soluble in most organic solvents. They occur in animal and vegetable tissue and are generally obtained by boiling or by extraction under pressure. They are important in the diet (DIETARY FATS) as a source of energy. (Grant & Hackh's Chemical Dictionary, 5th ed)

DrugDrug Description
Omega-3-acid ethyl estersA mixture of fatty acids used as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe hypertriglyceridemia.
alpha-Linolenic acidA polyunsaturated omega-3 fatty acid found in many supplements.
IcosapentA polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements.
Ricinoleic acidNot Available
DoconexentAn omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health.
Icosapent ethylAn ethyl ester of eicosapentaenoic acid (EPA) that reduces synthesis and enhances clearance of triglycerides that is used to treat patients with severe hypertriglyceridemia.
Soybean oilAn oil used as a source of calories and essential fatty acids in selected patients for total parenteral nutrition (TPN) therapy and prevention of essential fatty acid deficiency.
Safflower oilNo approved therapeutic indications.
Olive oilFor use in adults as a source of calories and fatty acids in total parenteral nutrition [FDA Label]. Sometimes used as an additive in cosmetic products.
Cocoa butterIndicated for topical use in over-the-counter skin products for the treatment of skin dryness and reduction of striae gravidarum (stretch marks).
Castor oilAn ingredient used in a variety of natural health products.
Omega-3 fatty acidsAn ingredient found in a variety of supplements and vitamins.
Sesame oilSesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic...
Cod liver oilAn ingredient found in a variety of nutritional products.
Linseed oilLinseed oil is a rich source of α-Linolenic acid extracted from the dried, ripened seeds of the flax plant Linum usitatissimum. Other fatty acids contained in linseed oil include palmitic...
Glyceryl TrioleateGlyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.
Resolvin E1Resolvin E1 (RX 10001) is under investigation in clinical trial NCT00941018 (Single and Multiple Ascending Oral Dose Study of Resolvin E1 in Healthy Volunteers).
Drugs & Drug Targets
Omega-3-acid ethyl estersSterol O-acyltransferase 1enzyme
Omega-3-acid ethyl estersSterol regulatory element-binding protein 1target
alpha-Linolenic acidFatty acid-binding protein, braincarrier
alpha-Linolenic acidFatty acid desaturase 1target
alpha-Linolenic acidFatty acid desaturase 2target
alpha-Linolenic acidSodium/calcium exchanger 1target
alpha-Linolenic acidTransient receptor potential cation channel subfamily V member 1target
alpha-Linolenic acidPeroxisome proliferator-activated receptor alphatarget
alpha-Linolenic acidBile acid receptortarget
alpha-Linolenic acidPeroxisome proliferator-activated receptor deltatarget
alpha-Linolenic acidPeroxisome proliferator-activated receptor gammatarget
alpha-Linolenic acidRetinoic acid receptor RXR-alphatarget
alpha-Linolenic acidElongation of very long chain fatty acids protein 2target
alpha-Linolenic acidElongation of very long chain fatty acids protein 5target
IcosapentProstaglandin G/H synthase 2target
IcosapentProstaglandin G/H synthase 1target
IcosapentFree fatty acid receptor 1target
IcosapentFatty acid desaturase 1target
IcosapentLong-chain-fatty-acid--CoA ligase 4target
IcosapentSodium/calcium exchanger 1target
IcosapentPeroxisome proliferator-activated receptor gammatarget
IcosapentPeroxisome proliferator-activated receptor deltatarget
IcosapentTransient receptor potential cation channel subfamily V member 1target
IcosapentPeroxisome proliferator-activated receptor alphatarget
IcosapentSerum albumincarrier
IcosapentFatty acid-binding protein, braintarget
IcosapentArachidonate 5-lipoxygenasetarget
Ricinoleic acidCannabinoid receptor 1target
Ricinoleic acidCannabinoid receptor 2target
Ricinoleic acidTransient receptor potential cation channel subfamily V member 1target
DoconexentCytochrome P450 2C9enzyme
DoconexentPeroxisome proliferator-activated receptor alphatarget
DoconexentPeroxisome proliferator-activated receptor gammatarget
DoconexentSterol regulatory element-binding protein 1target
DoconexentRetinoic acid receptor RXR-alphatarget
DoconexentRetinoic acid receptor RXR-betatarget
DoconexentRetinoic acid receptor RXR-gammatarget
DoconexentMyc proto-oncogene proteintarget
Soybean oilPeroxisome proliferator-activated receptor alphatarget
Castor oilProstaglandin E2 receptor EP3 subtypetarget
Castor oilProstaglandin E2 receptor EP4 subtypetarget
Omega-3 fatty acidsPeroxisome proliferator-activated receptor gammatarget
Omega-3 fatty acidsProstaglandin G/H synthase 2enzyme
Omega-3 fatty acidsArachidonate 5-lipoxygenaseenzyme
Omega-3 fatty acidsPeroxisome proliferator-activated receptor alphatarget
Omega-3 fatty acidsSterol regulatory element-binding protein 1target