Bradycardia-Causing Agents
- Name
- Bradycardia-Causing Agents
- Accession Number
- DBCAT002703
- Description
Not Available
- Drugs
Drug Drug Description Acebutolol A selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults. Agmatine Agmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety,... Alfentanil An opioid agonist used to induce and maintain anesthesia, as well as an analgesic. Alprenolol For the treatment of hypertension, angina, and arrhythmia Amiodarone A class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation. Amlodipine A calcium channel blocker used to treat hypertension and angina. Anisodamine Anisodamine has been investigated for the treatment of Intestinal Diseases. Aranidipine Aranidipine has been used for many years to treat angina pectoris and hypertension. Arotinolol Artinolol was introduced to be used as an antihypertensive agent since 1986. It has been studied for other functions like tremor control for patients with Parkinson disease and it is... Atenolol A synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients. Azelnidipine For the treatment of hypertension. Barnidipine A calcium channel blocker used to treat various forms of hypertension. Befunolol Used in the management of open angle glaucoma. PMID: 12480285. Bencyclane A vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels. Bendroflumethiazide A diuretic used to suppress lactation and to treat hypertension and edema. Benidipine A synthetic dihydropyridine calcium channel blocker used to treat hypertension and angina pectoris. Benzgalantamine A prodrug of galantamine, a competitive and reversible acetylcholinesterase inhibitor used in the management of mild-to-moderate dementia in patients with Alzheimer's disease. Bepridil For the treatment of hypertension, and chronic stable angina (classic effort-associated angina). Beractant A pulmonary surfactant used for the treatment and prevention of Respiratory Distress Syndrome (RDS) in premature infants. Betaxolol A cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically). Bevantolol For the treatment of angina pectoris and hypertension. Bioallethrin Bioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin. Bisoprolol A beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension. Bopindolol For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Bretylium A norepinephrine release inhibitor used for the prophylaxis and therapy of ventricular fibrillation, as well as the treatment of life-threatening ventricular arrhythmias. Bucindolol Bucindolol has been investigated in Heart Failure. Bufuralol Bufuralol is a new, non-selective -adrenoceptor blocking agent. Bupranolol Used to manage hypertension and tachycardia. Also used to treat glaucoma. Calfactant A lung surfactant for the prophylaxis of respiratory distress syndrome in high-risk infants. Carboxyamidotriazole Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others. Caroverine A calcium channel blocker indicated in the treatment of smooth muscle spasms, alcohol and drug withdrawal, and tinnitus. Carteolol A beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma. Carvedilol A non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients. Celiprolol A beta-blocker for the management of hypertension and angina pectoris. Ceritinib An antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib. Cilnidipine A dihydropyridine calcium channel blocker with action on both N- and L-type calcium channels used to treat hypertension. Cinnarizine A drug used for the management of labyrinthine disorder symptoms, including vertigo, tinnitus, nystagmus, nausea, and vomiting. Clevidipine A dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable. Clonidine An alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines. Cloranolol Not Annotated Crizotinib A receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive. Cyclandelate A vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis. Darodipine Darodipine is a calcium channel blocker. Dexmedetomidine An alpha-2 agonist used for sedation during various procedures. Dexniguldipine Not Annotated Dexverapamil Not Annotated Digoxin A cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation. Diltiazem A calcium channel blocker used to treat hypertension and to manage chronic stable angina. Donepezil An acetylcholinesterase inhibitor used to treat the behavioral and cognitive effects of Alzheimer's Disease and other types of dementia. Dotarizine A calcium antagonist used to treat and prevent migraines. Dronedarone An antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation. Efonidipine For the treatment of hypertension. Emopamil Prevents renal injury after warm & cold ischemia. Epanolol Epanolol is an beta blocker. Eperisone An antispasmodic that functions through voltage-gated channel blockade, notably with little to no sedation, effective in relaxing skeletal muscles and vascular smooth muscles. Esatenolol Esatenolol is a beta blocker. Esmolol A cardioselective beta-adrenergic blocker used for the short-term control of ventricular rate and heart rate in various types of tachycardia, including perioperative tachycardia and hypertension. Ethosuximide An anticonvulsant used to treat petit mal seizures. Felodipine A calcium channel blocker used to treat hypertension. Fendiline Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective. Fentanyl An opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management. Fingolimod A sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS) and studied to manage lung complications of COVID-19. Fish oil A source of essential fatty acids used as a source of calories in parenteral nutrition and as a dietary supplement. Flunarizine A selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments. Fluspirilene An antipsychotic agent used in the treatment of schizophrenia. Galantamine A cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease. Gallopamil Gallopamil has been used in trials studying the treatment of Asthma. Guanfacine An alpha-2A adrenergic receptor agonist used to treat ADHD. Indenolol Indenolol is a drug of the beta-adrenergic blocker class. Isradipine A dihydropyridine calcium channel blocker used for the treatment of hypertension. Ivabradine A HCN channel blocker used to reduce the risk of hospitalization for worsening heart failure in adult patients and for treatment of stable symptomatic heart failure as a result of dilated cardiomyopathy in pediatric patients. Labetalol An alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome. Lacidipine A lipophilic dihydropyridine calcium channel blocker with a slow onset of action used to treat hypertension. Lacosamide An antiepileptic drug used to treat partial-onset seizures and primary generalized tonic-clonic seizures. Lamotrigine A phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder. Landiolol A rapid-acting selective beta-blocker used to reduce ventricular rate in supraventricular tachycardia in adults. Lanreotide A somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly. Lercanidipine A calcium channel blocker for the management of hypertension. Levobetaxolol Used in the treatment of open-angle glaucoma and ocular hypertension [FDA Label]. Levobunolol A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Levomenthol An organic compound used to treat mild to moderate muscle and joint pain. Lidoflazine Not Annotated Lomerizine Lomerizine is a diphenylmethylpiperazine calcium channel blocker with relatively selective central nervous system (CNS) effects. This drug is used to prophylactically treat migraines and is also being investigated against eye-related... Loperamide A long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis. Lucinactant Intended for the prevention of respiratory distress syndrome (RDS) in premature infants at high risk for RDS. Magnesium sulfate A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. Manidipine A dihydropyridine calcium channel blocker used to treat hypertension. Mepindolol Mepindolol is a 2-methyl derivative of pindolol. It is a beta blocker. Methsuximide A succinimide anticonvulsant that increases the seizure threshold. Primarily used for childhood absence seizures. Functions by suppressing paroxysmal spike-and-wave patterns associated with lapses of consciousness in absence seizures. Methyldopa A centrally-acting alpha-2 adrenergic agonist used to manage hypertension alone or in combination with hydrochlorothiazide, and to treat hypertensive crises. Metipranolol A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Metoprolol A beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction. Mibefradil For the treatment of angina and high blood pressure. Midodrine An alpha-adrenergic agonist used to treat orthostatic hypotension. Nadolol A non-selective beta-adrenergic antagonist used for the management of arrhythmias, angina pectoris, and hypertension. Naftopidil Naftopidil has been investigated for the treatment of Disorder of Urinary Stent. Nebivolol A beta blocking agent used to treat hypertension and aid in the management of heart failure. Nicardipine A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina. Nifedipine A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. Niguldipine Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties. Niludipine Niludipine is a calcium channel blocker. Nilvadipine A calcium channel blocker used to manage arterial hypertension. Nimesulide A cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea. Nimodipine A calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm. Nisoldipine A calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension. Nitrendipine A dihydropyridine calcium channel blocker indicated in the treatment of arterial hypertension. Nylidrin A vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders. Octreotide A peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors. Otilonium A spasmolytic medication used to treat irritable bowel syndrome (IBS). Oxprenolol A non-selective beta-adrenergic antagonist used to treat hypertension, angina pectoris, arrhythmias, and anxiety. Pasireotide A somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate. Penbutolol A beta-adrenergic antagonist used for the management of mild to moderate arterial hypertension, alone or in combination with other antihypertensive agents. Penfluridol Not Annotated Perhexiline For the management of severe angina pectoris. Pinaverium A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract. Pindolol A beta adrenoceptor antagonist used to treat hypertension, edema, ventricular tachycardias, and atrial fibrillation. Poractant alfa A pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Practolol Used in the emergency treatment of cardiac arrhythmias. Pregabalin An anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants. Prenylamine Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias. Propafenone A Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias. Propranolol A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma. Regorafenib A kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma. Remifentanil An opioid analgesic used in anesthesia. Rivastigmine A cholinesterase inhibitor used to treat mild to moderate dementia in Alzheimer's and Parkinson's. Seletracetam Investigated for use/treatment in epilepsy. Sotalol A methane sulfonanilide beta adrenergic antagonist used to treat life-threatening ventricular arrhythmias and to maintain sinus rhythm in atrial fibrillation or flutter. Sufentanil An opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain. Talinolol Talinolol has been investigated for the basic science of Gastrointestinal Motility Disorder. Terodiline Not Annotated Tertatolol Tertatolol is a beta blocker. Tetrahydropalmatine Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity). Tetrandrine Not Annotated Timolol A non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma. Tizanidine An alpha-2 adrenergic agonist used for the short-term treatment of muscle spasticity. Tofacitinib A Janus kinase (JAK) inhibitor used to treat rheumatic conditions, such as rheumatoid arthritis and ankylosing spondylitis, and ulcerative colitis. Tolfenamic acid In the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults. Tranilast For the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. Trimebutine A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery. Trimethadione An anticonvulsant agent indicated for the control of treatment-refractory petit mal seizures. Verapamil A non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension. Vinpocetine A synthetic derivative of a vinca alkaloid used to treat neurological symptoms of cerebrovascular disease. WIN 55212-2 WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It... Zonisamide A sulfonamide anticonvulsant used to treat partial seizures. - Drugs & Drug Targets