Hyperhidrosis (DBCOND0012280)

Identifiers

Synonyms

Excessive sweating / Hyperhydrosis disorder (disorder) / Diaphoresis / Perspiration excessive / Sweating, function (observable entity) / Excess sweating / Heavy sweating / Drenching sweats / Excessive sweating (finding) / Sweating increased

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Aluminum chlorohydrate	A compound used as an antiperspirant.	No drug targets
Bornaprine	An anticholinergic drug indicated in the treatment of hyperhidrosis, dyskinesia, akathisia, parkinsonism, and Parkinson's disease.	No drug targets

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT05247333	Implementation of a Minor Ailment Service in Community Pharmacy Practice	No drug interventions	health_services_research	Not Available	completed
NCT01708551	Histological Analysis Following Ulthera System Treatment for Hyperhidrosis	No drug interventions	treatment	Not Available	completed
NCT02043145	Safety and Efficacy of BOTOX® (Botulinum Toxin Type A) in Korea	Botulinum toxin type A	Not Available	Not Available	completed
NCT04178161	Image Guided Targeted Photoablation for the Treatment of Localized Hyperhidrosis	No drug interventions	treatment	Not Available	unknown_status
NCT03694093	Assessing the Effect of Patient Characteristics on Treatment Response in Primary Hyperhidrosis	No drug interventions	Not Available	Not Available	completed
NCT05875285	Methotrexate Iontophoresis Versus Coal Tar Ointement in the Treatment of Primary Palmer Hyper Hidrosis	No drug interventions	treatment	Not Available	not_yet_recruiting
NCT01328015	A Study to Compare Oxybutynin to a Placebo in Women and the Effect on Plantar Hyperhidrosis	Oxybutynin	treatment	2	completed
NCT00168415	A Study Using Botulinum Toxin Type A in Adolescents With Axillary Hyperhidrosis	Botulinum toxin type A	treatment	4	completed
NCT01671800	Study to Assess the Efficacy of Botulinum Toxin B (Myobloc) for the Treatment of Prosthesis-associated Sweating	Botulinum toxin type B	treatment	1	completed
NCT01713959	Feasibility Study: Ulthera® System for the Treatment of Axillary Hyperhidrosis	No drug interventions	treatment	Not Available	completed
NCT02563899	Pharmacokinetic, Safety, Tolerability, and Clinical Effect of Topical Umeclidinium in Primary Axillary Hyperhidrosis	Umeclidinium	treatment	2	completed
NCT02552199	A Non-Interventional Study To Assess Sweating	No drug interventions	Not Available	Not Available	completed
NCT02479139	Clinical Trial To Evaluate ANT-1207 In Participants With Primary Axillary Hyperhidrosis	Botulinum toxin type A	treatment	2	completed
NCT03203174	The Use of Microneedles With Topical Botulinum Toxin for Treatment of Palmar Hyperhidrosis	Botulinum toxin type A	treatment	1	completed
NCT03647982	Anhidrotic Area and Safety of MEDITOXIN in Healthy Male Valunteers	Botulinum toxin type A	treatment	1	completed
NCT00004480	Study of Botulinum Toxin in Patients With Primary Hyperhidrosis	Botulinum toxin type A	treatment	Not Available	completed
NCT02854540	Management of Palmar Hyperhidrosis With Hydrogel-based Iontophoresis	No drug interventions	treatment	Not Available	completed
NCT01930604	Botulinum Toxin Treatment in Craniofacial, Inguinal, Palmar, Plantar and Truncal Hyperhidrosis	Botulinum toxin type A Botulinum toxin type B	treatment	2	unknown_status
NCT00228072	Liposuction as Treatment for Excessive Axillary Sweat	No drug interventions	treatment	2 / 3	completed
NCT04862546	Laser Acupuncture Versus Tap Water Iontophoresis on Hyperhidrosis	No drug interventions	treatment	Not Available	completed
NCT03816046	Hyperhydrosis Treatment Using Botulinum Toxin	Botulinum toxin type A	treatment	4	completed
NCT02099695	Evaluate the Efficacy of Oxybutynin Chloride in Patients With Primary Hyperhidrosis	Oxybutynin	treatment	3	withdrawn
NCT03024255	A Confirmatory Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis	Sofpironium	treatment	2	completed
NCT05108103	Determination of Longus Colli Muscle Thickness by Ultrasonography	No drug interventions	Not Available	Not Available	completed
NCT02336503	A Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis	Sofpironium	treatment	2	completed
NCT02058264	A Safety, Tolerability and Preliminary Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis	Sofpironium	treatment	1	completed
NCT00168402	A Study Using Botulinum Toxin Type A in Patients With Axillary Hyperhidrosis	Botulinum toxin type A	treatment	3	completed
NCT01934153	Characterization of Exposure From Topical Administration of [14C] Umeclidinium to Axilla or Palm of Healthy Male Subjects	Umeclidinium	treatment	1	completed
NCT02553798	Long-term Safety Study of Glycopyrronium in Subjects With Primary Axillary Hyperhidrosis	Ethanol Glycopyrronium	treatment	3	completed
NCT02733497	Cardiac Autonomic Changes After Endoscopic Thoracic Sympathectomy For Essential Palmar Hyperhidrosis	No drug interventions	treatment	Not Available	completed
NCT02728297	Staged Extended Thoracoscopic Sympathicotomy for Palmo-axillo-plantar Hyperhidrosis	No drug interventions	treatment	Not Available	completed
NCT04721483	T3-T4 Gray Sympathycotomy Versus Ramicotomy for Hyperhidrosis	No drug interventions	treatment	Not Available	completed
NCT00449683	Excessive Sweating Caused by Antidepressants: Measurement and Treatment With Terazosin	Terazosin	treatment	4	completed
NCT02633371	A Pilot Study Exploring the Efficacy and Safety of Topical Oxybutynin 3% Gel for Primary Focal Hyperhidrosis in Adolescents and Young Adults	Oxybutynin	treatment	Not Available	completed
NCT06113978	Thoracoscopic Sympathetic Chain Interruption for Palmar Hyperhidrosis in Patients Below 18	No drug interventions	treatment	Not Available	completed
NCT01855256	Treatment of Hyperhidrosis With Oxybutynin	Oxybutynin	treatment	3	completed
NCT02016885	A Dose-Ranging Study of the Effect of Glycopyrrolate in Subjects With Axillary Hyperhidrosis	Glycopyrronium	treatment	2	completed
NCT02565732	Safety and Efficacy of Botulinum Toxin Type A Topical Gel for Primary Axillary Hyperhidrosis	Botulinum toxin type A	treatment	2	completed
NCT03433859	Topical Aluminium Chloride vs OnabotulinumtoxinA Intradermal Injections in Residual Limb Hyperhidrosis (Lower Limbs)	Botulinum toxin type A	treatment	3	completed
NCT01140659	Objective Evaluation of Patients With Palmar Hyperhidrosis Submitted to Two Levels of Sympathectomy: T3 and T4.	No drug interventions	treatment	Not Available	completed
NCT02973659	The Use of Topical Oxybutynin 10% for Treating Primary Focal Hyperhidrosis-axillary, Palmar and Plantar.	Oxybutynin	treatment	Not Available	completed
NCT04924036	Qbrexza Cloths for Hyperhidrosis of Amputation Sites	Glycopyrronium	treatment	2	completed
NCT02673619	A Study to Evaluate Clinical Effect, Pharmacokinetics , Safety, and Tolerability of Umeclidinium in Palmar Hyperhidrosis Subjects	Umeclidinium	treatment	2	completed
NCT01588717	Excessive Sweating Caused by Antidepressants: Measurement and Treatment With Glycopyrrolate (AIDES-G)	Glycopyrronium	treatment	1	terminated
NCT05102396	Topical Oxybutynin for Treatment of Hyperidrosis: Local or Systemic Effect?	Oxybutynin	treatment	2	recruiting
NCT05805696	Treatment and Mapping of Impostor Phenomenon	No drug interventions	treatment	Not Available	recruiting
NCT00509886	Non-prescription Versus Prescription Topical Treatments Versus no Treatment in the Control of Sweating	No drug interventions	prevention	Not Available	completed
NCT02193139	Safety and Efficacy of an Anticholinergic Agent for Treatment of Primary Axillary Hyperhidrosis	No drug interventions	treatment	2	completed
NCT03416348	Hyperhidrosis, Developing a Treatment Approach Aims 1 & 2	Aluminum chloride Ethanol	treatment	1	completed
NCT01713673	Feasibility Study: Safety and Efficacy of the Ulthera® System for Treatment of Axillary Hyperhidrosis	No drug interventions	treatment	Not Available	completed
NCT02129660	Comparator Study of the Effect of Glycopyrrolate and Glycopyrronium in Subjects With Axillary Hyperhidrosis	Glycopyrronium	treatment	2	completed
NCT02530294	Study of Glycopyrronium in Subjects With Axillary Hyperhidrosis	Ethanol Glycopyrronium	treatment	3	completed
NCT01810991	Investigation of Hyperhidrosis Treatment Using the Nd: YAG 1440nm Wavelength Laser	No drug interventions	treatment	Not Available	completed
NCT01956591	Long Term Results of the Use of Oxybutynin for the Treatment of Hyperhidrosis	Oxybutynin	Not Available	Not Available	completed
NCT00168480	A Study Using Botulinum Toxin Type A in Patients With Axillary Hyperhidrosis	Botulinum toxin type A	treatment	4	completed
NCT05501444	Antiperspirant in the Treatment of Residual Limp Hyperhidrosis for Prosthetic Users	No drug interventions	treatment	Not Available	completed
NCT01811004	Evaluation of 1440nm Laser vs. Botulinum Toxin or miraDry® Microwave For Treatment of Axillary Hyperhidrosis	No drug interventions	treatment	Not Available	completed
NCT02100072	Evaluation of 1440nm Laser Assisted Selective Photothermolysis for Treatment of Axillary Hyperhidrosis	No drug interventions	treatment	Not Available	completed
NCT03236012	Hyperhidrosis in Patients With Amputations-Botox	Botulinum toxin type A Iodine	treatment	1	completed
NCT01310712	Use of Oxybutynin for Treating Hyperhidrosis: A Placebo-control Study	Oxybutynin	treatment	4	completed
NCT05403710	Botulinum Toxin Therapy in Hidradenitis Suppurativa	Botulinum toxin type A	Not Available	Not Available	recruiting
NCT05546710	miraDry Post Market Tumescent Anesthesia Study	No drug interventions	treatment	Not Available	withdrawn
NCT02530281	Study of Glycopyrronium in Axillary Hyperhydrosis	Ethanol Glycopyrronium	treatment	3	completed
NCT04906655	An Open Label Study for Palmar Hyperhydrosis	Glycopyrronium	treatment	2	completed
NCT04263623	Clinical Study to Assess the Efficacy and Safety of AT-5214 in the Treatment of Subjects With Palmar Hyperhidrosis	Dexmecamylamine	treatment	2	unknown_status
NCT02682238	A Safety, Tolerability and Preliminary Efficacy Study of BBI-4000 Gel in Subjects With Palmar Hyperhidrosis	Sofpironium	treatment	2	completed
NCT01128738	GSK1358820 (Botulinum Toxin A) PhIII DB & OL Study in Patients With Axillary Hyperhidrosis	No drug interventions	treatment	3	completed