Aortic Stenosis (DBCOND0030894)

Identifiers

Synonyms
Stenosis, Aortic / Stenoses, Aortic / Aorta Stenosis / Aortic stenosis / Nonrheumatic aortic (valve) stenosis / Aortic Valve Stenosis / Aortic valve stenosis (disorder) / Stenosis aortic valve

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05768594
Omics in Valvular DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT05983458
SAfe and Fast Discharge With Acurate Valve in Low Risk tavI PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT04347603
Sedation or General Anesthesia During TAVRNo drug interventionstreatmentNot Availablecompleted
NCT05714293
CT-evaluation of Coronary Ostia Height After Surgical Aortic Valve Replacement.No drug interventionsbasic_scienceNot Availableenrolling_by_invitation
NCT04714268
Comparison of Aorto-iliac Endovascular Interventions With and Without the EndoNaut WorkstationNo drug interventionsNot AvailableNot Availableunknown_status
NCT03735667
ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve ReplacementNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT06470022
Comparison of Evolut FX Versus Sapien 3 Ultra Resilia.No drug interventionstreatmentNot Availablerecruiting
NCT06580158
AI in Outpatient Practice for Diagnosing Aortic Stenosis and Diastolic DysfunctionNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06652841
Feasibility Study of the transShield Embolic Protection SystemNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02088554
PERIGON Pivotal TrialNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT04204915
The Early Valve Replacement in Severe ASYmptomatic Aortic Stenosis StudyNo drug interventionspreventionNot Availablerecruiting
NCT06008080
Post-Market Clinical Follow Up Study with Navitor ValveNo drug interventionsNot AvailableNot Availablerecruiting
NCT06055751
Long Term Evaluation of Cardiac Arrhythmias After Transcatheter Aortic Valve Implantation -The LOCATE RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT06211296
The ShortCut™ Continued Access Study ProtocolNo drug interventionspreventionNot Availableactive_not_recruiting
NCT06638268
Transcatheter AortiC Valve Implantation in AorTic StenosIs CardiogenIc ShockNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06171737
Promoting Shared Decision Making for Severe Aortic StenosisNo drug interventionshealth_services_researchNot Availableenrolling_by_invitation
NCT05646381
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosistreatment2recruiting
NCT05384418
Cardiac Amyloidosis Prevalence and Outcome in Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve ImplantationNo drug interventionsdiagnosticNot Availablecompleted
NCT06007222
Non-antithrombotic Therapy After Transcatheter Aortic Valve Implantation Trialtreatment4recruiting
NCT06047561
The Scottish Aortic Stenosis LongiTudinal Imaging and biomarkeR (SALTIRE) ProgrammeNo drug interventionsNot AvailableNot Availablerecruiting
NCT06551610
CAN3T - Canadian TAVI Triage ToolNo drug interventionshealth_services_researchNot Availablenot_yet_recruiting
NCT06595407
Loss of Y Chromosome in Aortic StenosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT06597188
TAVR Vs. SAVR Study of VitaFlow Liberty® for Severe BAV StenosisNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02833090
The Plasma Serotonin and Aortic Stenosis: a Pilot Study.No drug interventionsdiagnosticNot Availablecompleted
NCT03883490
Role of Elastin Metabolites in Aortic Remodelling in ASNo drug interventionsNot AvailableNot Availablecompleted
NCT02545790
Cardiac Remodeling and Circulating Biomarkers in Pediatric Left Ventricular Pressure Loading LesionsNo drug interventionsNot AvailableNot Availablecompleted
NCT02768064
Temporary Pacemaker in Transcatheter Aortic Valve Implantation PatientsNo drug interventionstreatmentNot Availableunknown_status
NCT02786264
Association of Type of Anesthetic and Outcomes in Transfemoral Aortic Valve ReplacementNot AvailableNot Availablecompleted
NCT06121921
RESTORE-TAVI PilotNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT01742702
HaemoDYNAMICs in Primary and Secondary HypertensionNot AvailableNot Availablerecruiting
NCT03831087
Cardiac Magnetic Resonance Imaging Versus Computed Tomography to Guide Transcatheter Aortic Valve ReplacementNo drug interventionsdiagnosticNot Availablecompleted
NCT01000233
Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular CalcificationsNo drug interventionsprevention2 / 3unknown_status
NCT03666351
Study to Evaluate the Effect on Improvement of LVH by the Control of BP in Hypertension Patients With AV Diseasetreatment4completed
NCT00805051
Acquired Von Willebrand Syndrome in Severe Aortic StenosisNo drug interventionsNot AvailableNot Availablecompleted
NCT05739253
Changes of Ascending Aortic Diameter in Patients Undergoing Transcatheter Aortic Valve ReplacementNo drug interventionsNot AvailableNot Availablerecruiting
NCT02672553
EDWARDS INTUITY Valve System CADENCE-MIS StudyNo drug interventionstreatmentNot Availablecompleted
NCT00092677
An Investigational Drug on Clinical Outcomes in Patients With Aortic Stenosis (Narrowing of the Major Blood Vessel of the Heart)(MK-0653A-043 AM4)(COMPLETED)treatment3completed
NCT04454177
SMART Watch Facilitated Early Discharge in Patients Undergoing Transcatheter Aortic Valve ReplacementNo drug interventionsNot AvailableNot Availablerecruiting
NCT03383445
Transcatheter Aortic Valve Replacement Versu Surgical Aortix Valve Replacement for Treating Elderly Patients With Severe Aortic Stenosis and Small Aortic Annuli: A Prospective Randomized Study The VIVA TrialNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03332745
Mechanism of Decompensation Evaluation - Aortic StenosisNo drug interventionsNot AvailableNot Availablecompleted
NCT01658345
Microvascular Dysfunction in Aortic StenosisNo drug interventionsNot AvailableNot Availablecompleted
NCT03088098
Comparison of Left Atrial Appendage Occlusion vs Standard Medical Therapy in Patients in AF Undergoing TAVINo drug interventionstreatmentNot Availableactive_not_recruiting
NCT02673697
Perceval Sutureless Implant Versus Standard-Aortic Valve ReplacementNo drug interventionstreatmentNot Availableterminated
NCT04496297
Non-contrast 3-dimensional Cardiac Magnetic Resonance ImagingNo drug interventionsNot AvailableNot Availablecompleted
NCT00693797
Clinical Significance of Collagen Metabolism Changes in Left Cardiac VentricleNo drug interventionsNot AvailableNot Availablecompleted
NCT03325283
The PROTEMBO SF TrialNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT06204783
Real-time Pressure Volume Loop Monitoring as a Guide for Enhanced Understanding of Changes in Elemental Cardiovascular Physiology During Therapeutic Strategies Aiming for Hemodynamic Optimization. Cohort II: Structural Heart Interventions (PLUTO-II)No drug interventionsNot AvailableNot Availablerecruiting
NCT05712161
Use of DurAVR™ THV System in Subjects With Severe Aortic Stenosis: Early Feasibility StudyNo drug interventionsdevice_feasibilityNot Availableactive_not_recruiting
NCT02950428
ACURATE Neo™ TA Delivery System in Patient With Severe Aortic StenosisNo drug interventionstreatmentNot Availablecompleted
NCT06499428
Ventricular Pacing Rate in Follow-up of Patients Treated With Definitive PM Implantation Post TAVINo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02076711
Myocardial Efficiency of the Left Ventricle in Asymptomatic Patients With Aortic Valve Stenosis - a Prognostic Marker and a Target for Intervention?No drug interventionstreatment2completed
NCT02626871
Atrial Fibrillation, Stroke, and Bleeding in Patients Undergoing Aortic Biovalve ImplantationNo drug interventionsNot AvailableNot Availablecompleted
NCT03084978
Conscious Sedation vs General Anesthesia in TAVR PatientsNo drug interventionstreatmentNot Availablewithdrawn
NCT01272388
Aortic Stenosis and PhosphodiEsterase iNhibition With Aortic Valve Replacement (ASPEN-AVR): A Pilot Studytreatment4terminated
NCT02890407
Genetics of Aortic Stenosis: From Family Forms to the Common FormsNo drug interventionsNot AvailableNot Availablecompleted
NCT01115907
Freedom SOLO Stentless Heart Valve StudyNo drug interventionstreatment3completed
NCT01845207
Frailty Assessment Before Cardiac Surgery & Transcatheter InterventionsNo drug interventionsNot AvailableNot Availablecompleted
NCT05851209
Biomarkers and Mechanisms of Disease Progression and Outcome of Aortic Stenosis in HumansNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04968509
Effect of PCSK9 Inhibitors on Calcific Aortic Valve Stenosistreatment3recruiting
NCT01648309
Neuropsychological Testing in Patients Undergoing Transvascular Aortic Valve ImplantationNo drug interventionsNot AvailableNot Availablewithdrawn
NCT02909556
ACURATE Neo™ AS Aortic Bioprosthesis for Implantation Using the ACURATE neoTM AS TF Transfemoral Delivery System in Patients With Severe Aortic StenosisNo drug interventionstreatmentNot Availablecompleted
NCT01638156
Cardiac MRI for Severe Aortic StenosisNo drug interventionsNot AvailableNot Availablecompleted
NCT02597985
Prehabilitation to Improve Functional and Clinical Outcomes in Patients With Aortic StenosisNo drug interventionstreatmentNot Availablecompleted
NCT01775215
A Comparison of Advanced Imaging Techniques in Aortic StenosisNo drug interventionsNot AvailableNot Availablewithdrawn
NCT05958537
High Flow Nasal Oxygen Cannula in Transcatheter Aortic Valve Replacement: Complications and BiomarkersNo drug interventionstreatmentNot Availablecompleted
NCT00567437
Utility of Exercise-induced N-terminal (NT) Pro-brain Natriuretic Peptide Levels in Predicting Prognosis in Asymptomatic Aortic StenosisNo drug interventionsdiagnosticNot Availableterminated
NCT06481137
Reversibility of Cardiac Conduction Disturbances Following TAVINo drug interventionsdiagnosticNot Availablerecruiting
NCT02986737
ACURATE Neo™ Aortic Bioprosthesis for Implantation Using the ACURATE TA™ LP Transapical Delivery System in Patients With Severe Aortic StenosisNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT02504632
Study of Platelet Activation by Severe Aortic Stenosis and Its Correction by Transcatheter Aortic Valve ImplantationNo drug interventionsotherNot Availablecompleted
NCT01161732
Early Surgery Versus Conventional Treatment in Very Severe Aortic StenosisNo drug interventionstreatmentNot Availablecompleted
NCT01794832
Severe Aortic Stenosis in Patients Referred for Valve SurgeryNo drug interventionsNot AvailableNot Availableunknown_status
NCT04860752
SAPIEN 3 Ultra EU PMSNo drug interventionsNot AvailableNot Availablecompleted
NCT03442400
A Prospective Study of Fractional Flow Reserve Assessment of Intermediate Coronary Stenoses in Severe Aortic StenosisNo drug interventionsdiagnosticNot Availableterminated
NCT03423459
CoreValve Evolut Pro Prospective RegistryNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02663375
ACURATE TA™ Valve Implantation Registry: SAVI 2No drug interventionsNot AvailableNot Availablecompleted
NCT04552275
The HALT Biomarker StudyNo drug interventionsdiagnostic1recruiting
NCT04913870
Angiotensin Receptor Blockers in Aortic Stenosistreatment4recruiting
NCT03557242
Strategies to Prevent Transcatheter Heart Valve Dysfunction in Low Risk Transcatheter Aortic Valve ReplacementNo drug interventionstreatmentNot Availableunknown_status
NCT00535899
Speckle Tracking Imaging in Patients With Low Ejection Fraction Aortic Stenosis (SPArKLE-AS)No drug interventionsNot AvailableNot Availableterminated
NCT02628899
Feasibility of Transcatheter Aortic Valve Replacement in Low-Risk Patients With Symptomatic, Severe Aortic StenosisNo drug interventionstreatmentNot Availablecompleted
NCT01755936
The Role of Myocardial Fibrosis in Patients With Aortic StenosisNo drug interventionsNot AvailableNot Availablecompleted
NCT04178213
First in Human Feasibility Study With ADAPT 3D - ALR for Aortic Leaflet RepairNo drug interventionstreatmentNot Availableunknown_status
NCT05484713
Feasibility of 3D Printed Models of Aortic Stenosis in Guiding TAVI ProcedureNo drug interventionsNot AvailableNot Availableunknown_status
NCT03095313
18-F Sodium Fluoride (18F-NaF) PET for the Assessment of Bioprosthetic Aortic Valve Durability and OutcomesNo drug interventionsdevice_feasibility2active_not_recruiting
NCT03466918
China S3: Safety and Effectiveness of Edwards Lifesciences SAPIEN 3 THV in the Chinese PopulationNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03424941
The TransCatheter Valve and Vessels TrialNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT04234841
Avr Thrombosis OutcoMe StudyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02073617
Aortic Valve and Root Measurements Under Real-Time 3-Dimensional Visualization During AngiographyNo drug interventionsdiagnosticNot Availablecompleted
NCT05886517
Transfemoral Transcatheter Aortic Valve Implementation at Hospital Without On-site Cardiac Surgery: Early Clinical Outcome in Patients With Prohibitive Surgical Risk.No drug interventionstreatmentNot Availablerecruiting
NCT02841917
Reactive Oxygen Species Following Aortic Valve ReplacementNo drug interventionsNot AvailableNot Availablecompleted
NCT02202434
Safety and Efficacy Study of Lotus Valve for Transcatheter Aortic Valve ReplacementNo drug interventionstreatmentNot Availableterminated
NCT04678934
Cerebral Lesion and Neurocognitive Status Changes After TAVRNo drug interventionsNot AvailableNot Availableunknown_status
NCT02058134
The CardioPAT Project: A Randomized TrialNo drug interventionstreatmentNot Availableterminated
NCT04564534
Impact of Pre-procedure Cognitive Status on Outcome at 3 Months After Transcatheter Aortic Valve ImplantationNo drug interventionsNot AvailableNot Availablecompleted
NCT04160624
Transcatheter Aortic Valve Replacement With Extracorporeal Life System SupportNo drug interventionstreatmentNot Availableunknown_status
NCT02617524
Dedicated Sheath Feasibility StudyNo drug interventionstreatmentNot Availableunknown_status
NCT00584116
Balloon Aortic Valvuloplasty During Surgical Aortic Valve ReplacementNo drug interventionsNot AvailableNot Availablecompleted
NCT02329496
REPRISE Next Generation Delivery SystemNo drug interventionstreatmentNot Availablecompleted
NCT03268135
Heart Failure and Aortic Stenosis TranscriptomeNo drug interventionsNot AvailableNot Availablerecruiting
NCT02907463
EDWARDS INTUITY Elite Valve SystemNo drug interventionsNot AvailableNot Availablecompleted
NCT05614986
Prospective Evaluation of Neurocognition in Patients Undergoing Transcatheter Aortic Valve ReplacementNo drug interventionsNot AvailableNot Availablerecruiting
NCT05230225
Electronic Physician Notification to Facilitate the Recognition and Management of Severe Aortic Stenosis: The DETECT AS TrialNo drug interventionstreatmentNot Availablerecruiting
NCT04420325
COronary and MICrocirculatory Measurements in Patients With Aortic Valve Stenosis.No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04744857
Safety and Efficacy of TaurusOne® Transcatheter Aortic Valve Replacement System With Retrievable Delivery Catheter SystemNo drug interventionstreatmentNot Availablecompleted
NCT03314857
China XT: Safety and Effectiveness of Edwards Lifesciences SAPIEN XT THV in the Chinese PopulationNo drug interventionstreatmentNot Availablecompleted
NCT00774657
Ventricular Remodeling In Patients With Aortic Stenosis Assessed EchocardiographyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT02351726
Mitroflow DL Post Approval Study- North AmericaNo drug interventionstreatmentNot Availableterminated
NCT00830726
Water- and Salt-homeostasis in Healthy Humans, and in Patients With Heart- or Lung DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT02306226
Symetis ACURATE Neo™ Valve Implantation SAVI TF RegistryNo drug interventionsNot AvailableNot Availablecompleted
NCT03965065
Comparison of Sutureless Vs. Standard Biological Prostheses for Surgical Aortic Valve ReplacementNo drug interventionstreatmentNot Availableunknown_status
NCT02856620
The Role of Cardiac Mechanics, Biomarkers and Frailty in Aortic StenosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT04157920
Impact of Predilatation Between Self-expanding ValvesNo drug interventionstreatmentNot Availablecompleted
NCT01876420
The Medtronic CoreValve™ Evolut R™ CE Mark Clinical StudyNo drug interventionstreatmentNot Availablecompleted
NCT05721820
Aortic Cross-clamp and Opening After Transcatheter Aortic Valve Implantation: a Real Issue?No drug interventionsNot AvailableNot Availablecompleted
NCT01941420
Comparison of Blood and Crystalloid CardioplegiaNo drug interventionsNot AvailableNot Availablecompleted
NCT04166682
Impact of Home-based Cardiac Rehabilitation on Outcomes After TAVRNo drug interventionssupportive_careNot Availableunknown_status
NCT05539573
PROVE ACURATE neo2™ - Post Market Safety and Performance Surveillance in Aortic StenosisNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04915976
TAVI and Gender Outcomes Aortic Stenosis Undergoing Transfemoral Transcatheter Aortic Valve Implantation.No drug interventionsNot AvailableNot Availablesuspended
NCT00338676
Aortic Stenosis in Elderly : Determinant of ProgressionNo drug interventionsNot AvailableNot Availableunknown_status
NCT06248294
PRogression Of bicuSPid-rElated aoRtOpathy in Patients Undergoing Transcatheter Aortic Valve Implantation (PROSPERO-TAVI)No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02639494
Self-Centering Guide Catheter Feasibility StudyNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT06255691
10-year Follow-up After Aortic Valve Replacement SurgeryNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04899180
Prevalence of Transthyretin Cardiac Amyloidosis in Clinically Significant Aortic StenosisNo drug interventionsdiagnostic0completed
NCT02921880
Does Cardiac REhabilitation Improve Functional, Independence, Frailty and Emotional outCOmes Following Trans Catheter Aortic ValvE Replacement?No drug interventionssupportive_careNot Availablecompleted
NCT06136689
Role of Aortic Valve Composition in Pathophysiology and Diagnosis of Aortic StenosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT03352089
Positron Emission Tomography / Magnetic Resonance Imaging in Aortic StenosisNo drug interventionsNot AvailableNot Availablecompleted
NCT04636892
Evaluating Infrasonic HemodynographyNo drug interventionsdiagnosticNot Availablerecruiting
NCT01598844
JUPITER Study: Transapical Aortic Valve Implantation for Aortic RegurgitationNo drug interventionsNot AvailableNot Availablecompleted
NCT02005640
Transcatheter Heart Valve (THV) Sizing and Leakage After Transcatheter Aortic Valve Implantation (TAVI) Before and After Establishing Routine Preprocedure Multi Slice Computerized Tomography (MSCT) Aortic Assessment. A Retrospective Registry StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT03225001
PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - Nested Registry 3/Valve-in-ValveNo drug interventionstreatmentNot Availablecompleted
NCT01334801
Biomarkers in Aortic Stenosis - B.A.S.S.No drug interventionsNot AvailableNot Availablecompleted
NCT06372301
Dobutamine Stress Echocardiography in LF/LG Aortic Stenosis and Wild-type Transthyretin Amyloid CardiomyopathyNo drug interventionsdiagnosticNot Availablerecruiting
NCT01672268
Interest of Cardiac Computed Tomography to Optimize and Improve the Procedure of TAVINo drug interventionstreatment3completed
NCT02146768
Low-dose-contrast Cardiac Computed TomographyNo drug interventionsNot AvailableNot Availablecompleted
NCT01605669
Correlation of Auscultatory Severity of Aortic Stenosis With Trans Thoracic EchocardiographyNo drug interventionsNot AvailableNot Availablecompleted
NCT04786769
Iron Supplementation in TAVI and SAVR Patients With Iron Deficiencytreatment4not_yet_recruiting
NCT01966146
Examination of Valve Insufficiency Before and After MitraClip or TAVI Procedure by 3D Echocardiography Compared to MRINo drug interventionsdiagnosticNot Availablecompleted
NCT05171712
Portico and Navitor India Clinical TrialNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT04930510
Coronary Artery Disease in Elderly People Referred for TAVINo drug interventionsNot AvailableNot Availableunknown_status
NCT03995914
Depression and Major Adverse Events in Older Patients Who Undergo a Transcatheter Aortic Valve ImplantationNo drug interventionsNot AvailableNot Availablewithdrawn
NCT02686814
PERIGON Japan TrialNo drug interventionstreatmentNot Availablecompleted
NCT02745314
Frailty and Mortality in Older Old With Severe Aortic StenosisNo drug interventionsNot AvailableNot Availablecompleted
NCT02491255
Safety and Efficacy Study of Lotus Valve for Transcatheter Aortic Valve Replacement (REPRISE Japan)No drug interventionstreatmentNot Availablecompleted
NCT05889208
Prophylactic Permanent Pacemaker in Patients With Right Bundle Branch Block Undergoing Transcatheter Aortic Valve ImplantationNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04827238
Standardized Invasive Hemodynamics for Elevated Gradients Post TAVR (DISCORDANCE TAVR)No drug interventionsNot AvailableNot Availablerecruiting
NCT01755338
Effect of Steroids on Cerebral Inflammation and Neuronal Damage After Surgical Aortic Valve ReplacementtreatmentNot Availablecompleted
NCT01237743
Microembolic Signals and Serum Markers of Neuronal Damage During Transcatheter Aortic Valve Implantation.No drug interventionsNot AvailableNot Availablecompleted
NCT01395303
Polymorphisms in the Vitamin D System and HealthNo drug interventionsNot AvailableNot Availablecompleted
NCT01448421
DEFLECT I: Keystone Heart Embolic Deflection TrialNo drug interventionspreventionNot Availablecompleted
NCT01645202
A Comparison of Transcatheter Heart Valves in High Risk Patients With Severe Aortic Stenosis: The CHOICE TrialNo drug interventionstreatmentNot Availablecompleted
NCT02390102
Erythropoietin + Iron Therapy for Anemic Patients Undergoing Aortic Valve Replacementtreatment3completed
NCT04068402
Vivio AS (Aortic Stenosis) Algorithm Optimization StudyNo drug interventionsdiagnosticNot Availablewithdrawn
NCT00329979
Femoral vs Radial Approach and MRI Evaluation of StrokesNo drug interventionsNot AvailableNot Availablecompleted
NCT04627987
Mechanisms of Excess Risk in Aortic StenosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT02739087
Radiation-Free Heart Catheterization Using MRINo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT02338154
EDWARDS INTUITY Valve System FOUNDATION StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT03600051
Automated Phonocardiography Analysis in AdultsNo drug interventionsNot AvailableNot Availablecompleted
NCT02688153
EDWARDS INTUITY Valve System CADENCE StudyNo drug interventionstreatmentNot Availablecompleted
NCT05035277
AntiCoagulation Versus AcetylSalicylic Acid After Transcatheter Aortic Valve Implantationprevention3recruiting
NCT02010177
Clinical Outcome of Patients With Low-gradient Severe Aortic StenosisNo drug interventionsNot AvailableNot Availablesuspended
NCT02695147
Direct Aortic vs Subclavian Access for TAVI: a Review of the Outcomes in the UKNo drug interventionsNot AvailableNot Availableunknown_status
NCT05224245
ACURATE Prime XL Human Feasibility StudyNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT02089945
Pilot Study of Cognitive and Functional Outcomes Following TAVINo drug interventionsNot AvailableNot Availablecompleted
NCT04406805
TMAO in Patients With Severe Aortic StenosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT06069661
U.S. Multicenter Feasibility Trial of the F2 Filter and Delivery System for Embolic Protection During TAVRNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02629328
CardioCel Tri-leaflet Repair StudyNo drug interventionstreatmentNot Availablecompleted
NCT04996693
On Dose Efficiency of Modern CT-scanners in Chest ScansNo drug interventionsdiagnosticNot Availablecompleted
NCT02060071
Endothelial Progenitors in Aortic Stenosis: Association With Aortic Stenosis Progression and SeverityNo drug interventionshealth_services_research4unknown_status
NCT02174471
Regression of Myocardial Fibrosis After Aortic Valve ReplacementNo drug interventionsNot AvailableNot Availablecompleted
NCT03310671
Aortic Stenosis in Subjects With Heterozygous Familial Hypercholesterolemia on Prolonged Treatment With StatinsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02760771
Transfemoral Transcatheter Aortic Valve Implantation With or Without Predilation of the Aortic Valve (EASE-IT TF)No drug interventionsNot AvailableNot Availablecompleted
NCT04414878
VitaFlow™ II Transcatheter Aortic Valve System Pre-market TrialNo drug interventionstreatmentNot Availablerecruiting
NCT06009588
Comparison of Self- and Balloon-expandable Valves in Patients With Ascending Aortic Dilation Undergoing Transcatheter Aortic Valve Replacement: The AAD-CHOICENo drug interventionstreatmentNot Availablerecruiting
NCT02740088
18F-NaF Uptake and Aortic Stenosis ProgressionNo drug interventionsNot AvailableNot Availableunknown_status
NCT05002088
Portico Valve-in-Valve Retrospective RegistryNo drug interventionsNot AvailableNot Availablecompleted
NCT02628509
Von Willebrand Factor As a Biological Sensor of Blood Flow in Percutaneous Cardiac ProcedureNo drug interventionsNot AvailableNot Availableunknown_status
NCT01736956
Fetal Intervention for Aortic Stenosis and Evolving Hypoplastic Left Heart SyndromeNo drug interventionstreatmentNot Availablecompleted
NCT02698956
SOURCE 3: Observational Study to Evaluate Safety and Performance of SAPIEN 3 THV System in Real Life PracticeNo drug interventionsNot AvailableNot Availablecompleted
NCT02448485
High-Sensitivity Troponin T Plasma Levels in Patients With Aortic Stenosis (Tyrolean Aortic Stenosis Study-2)No drug interventionsNot AvailableNot Availablerecruiting
NCT04815785
Safety and Efficacy of TaurusOne® Transcatheter Aortic Valve System in Patients With Severe Calcific Aortic StenosisNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT04696185
Dapagliflozin After Transcatheter Aortic Valve Implantationtreatment4active_not_recruiting
NCT02321137
Left Atrial Appendage CLOSURE for the Prevention of Thromboembolisms in Patients Undergoing Aortic Bioprosthesis SurgeryNo drug interventionstreatmentNot Availablerecruiting
NCT04797832
IV Sodium Ferric Gluconate Complex in Patients Undergoing TAVItreatment4recruiting
NCT04056832
Left Ventricular Reverse Remodeling In Aortic Valve Replacement With Single Strip Pericardium Versus Mechanical ValveNo drug interventionstreatmentNot Availableunknown_status
NCT02122900
Prospective Balloon Aortic ValvuloplastyNo drug interventionsNot AvailableNot Availablecompleted
NCT02516800
Prevalence and Significance of Mutations in Genes Encoding NaPi-co-transporters in the Development of CAVDNo drug interventionsNot AvailableNot Availableunknown_status
NCT00800800
Effects of Rosuvastatin on Aortic Stenosis Progressiontreatment3completed
NCT01404975
TAVI Protocol - Paravertebral Block StudyNo drug interventionstreatmentNot Availablecompleted
NCT00788242
The Effect of Glucose-Insulin-Potassium Infusion in Patients Undergoing Cardiac SurgerytreatmentNot Availablecompleted
NCT03003299
PARTNER 3 Trial - Aortic Valve-in-ValveNo drug interventionstreatmentNot Availablerecruiting
NCT01319799
Microembolic Signals and Cerebrospinal Fluid Markers of Neuronal Damage After Surgical Aortic Valve ReplacementNo drug interventionsNot AvailableNot Availablecompleted
NCT03250806
Early Detection of Aortic Stenosis in the Community During Flu VaccinationNo drug interventionsNot AvailableNot Availablecompleted
NCT04982406
Transcatheter Aortic Valve Replacement (TAVR) Effects on Cardiac Conduction SystemNo drug interventionsNot AvailableNot Availablerecruiting
NCT01575249
Identification of Parameters in rapId-proGression Subgroup Patients With Moderate Aortic StenosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT00375336
Risk Factors Associated With Calcification of the Aortic ValveNo drug interventionsNot AvailableNot Availableunknown_status
NCT01358513
Role of Active Valvular Calcification and Inflammation in Patients With Aortic StenosisNo drug interventionsNot AvailableNot Availablecompleted
NCT02053818
Remifentanil/Sufentanil for CABG+/-AVR Evaluated by Recovery, Cognitive Function, Haemodynamics and Biochemical Markers.prevention4completed
NCT04126018
Comparative Imaging Assessment of Valvular Heart DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT02101619
Assessment of Myocardial Tissue Damage in Aortic StenosisNo drug interventionsNot AvailableNot Availablecompleted
NCT00252317
Acute Haemodynamic Effects of Treatment With Angiotensin Converting Enzyme (ACE)-Inhibitors in Patients With Symptomatic Aortic Stenosistreatment4unknown_status
NCT04009434
Treatment of Concomitant Mitral Regurgitation by Mitral Valve Clipping in Patients With Successful Transcatheter Aortic Valve Implantation.No drug interventionstreatmentNot Availableunknown_status
NCT06472934
Impact of Beta-blocker on Outcome Among Patients Undergoing Transcatheter Aortic Valve Replacement (B-TAVR)No drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04066634
Vivio AS (Aortic Stenosis) Detection StudyNo drug interventionsdiagnosticNot Availablecompleted
NCT03879824
Radial Versus Femoral Secondary Access During TAVINo drug interventionstreatmentNot Availableterminated
NCT06076824
Glucocorticoid Treatment in Transaortic Valve Replacement to Reduce the Incidence of Conduction Disturbances (GLUCO-TAVR).prevention4recruiting
NCT04722796
HANGZHOU Solution in Bicuspid AS Undergoing TAVRNo drug interventionstreatmentNot Availablerecruiting
NCT01579058
Effect of Bisoprolol on Progression of Aortic Stenosistreatment4terminated
NCT04350658
TAVR Without PredilatationNo drug interventionsNot AvailableNot Availableunknown_status
NCT03140735
Interest of Pulse Wave Velocity Measurement as a Predictor of Severity of Aortic StenosisNo drug interventionsotherNot Availablewithdrawn
NCT02687035
PARTNER II Trial: S3iCAPNo drug interventionstreatmentNot Availablecompleted
NCT06021535
Involvement of the Gut Microbiota in Calcified Aortic StenosisNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01275339
Aortic Stenosis and PhosphodiEsterase Type 5 iNhibition (ASPEN): A Pilot Studytreatment4terminated
NCT01144039
Glutamate and Diastolic Function in Patients Undergoing Aortic Valve RepairNo drug interventionstreatment4completed
NCT05673525
A Clinical Trial of the Transcatheter Aortic Valve Implantation System With a Prospective, Multi-Center, One-Arm Approach to Evaluate the Efficacy and Safety in the Treatment of Patients With Severe Aortic StenosisNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05070130
OpSens PRIME CLASSNo drug interventionsNot AvailableNot Availableterminated
NCT00722748
Genomic Investigation of Cardiovascular DiseasesNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03847948
Biological Factors Associated With Subclinical Valvular ThrombosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT03846557
PRospective Evaluation Complementing Investigation With Acurate Neo DeviceNo drug interventionsNot AvailableNot Availableunknown_status
NCT03029026
The Role of Occult Cardiac Amyloid in the Elderly With Aortic Stenosis.No drug interventionsNot AvailableNot Availableunknown_status
NCT01757665
ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New Tissue Treatment Platform (COMMENCE)No drug interventionstreatmentNot Availableactive_not_recruiting
NCT04031274
Transcatheter Treatment for Combined Aortic and Mitral Valve Disease. The Aortic+Mitral TRAnsCatheter (AMTRAC) Valve RegistryNo drug interventionsNot AvailableNot Availableunknown_status
NCT00348920
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve SurgeryNo drug interventionspreventionNot Availablecompleted
NCT01060020
Acute Hemodynamic Effects of Sildenafil in Patients With Severe Aortic Stenosistreatment4completed
NCT02974920
Rivaroxaban or Aspirin for Biological Aortic Prosthesisprevention4unknown_status
NCT02903420
A Clinical Trial of Transcatheter Aortic Valves in Dialysis Patients (Japan)No drug interventionstreatmentNot Availableactive_not_recruiting
NCT05603520
Phenotyping Heterogeneity and Regionality of the AortaNo drug interventionsNot AvailableNot Availablerecruiting
NCT05893082
Multicenter Feasibility Trial of the F2 Filter and Delivery System for Embolic Protection During TAVRNo drug interventionstreatmentNot Availablerecruiting
NCT05241431
Effect of Dapagliflozin on Myocardial and Renal Function Following Aortic Valve Stenosis InterventionNo drug interventionstreatment2 / 3unknown_status
NCT01991431
ROUTE Registry Of the Utilisation of the Transaortic (Tao) TAVI Approach Using the Edwards Sapien XT ValveNo drug interventionsNot AvailableNot Availablecompleted
NCT06129331
Aortic Stenosis and Cardiac AmyloidosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT01676727
ADVANCE Direct Aortic StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT06128876
CMR-AI and Outcomes in Aortic StenosisNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02023060
Functional and Quality of Life Improvement Following Transcatheter Heart Valve ImplantationNo drug interventionsNot AvailableNot Availablerecruiting
NCT04268160
GPx Activity in Subjects With Aortic Stenosis Undergoing TAVRNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03454360
CHANGE Neo™ TA Registry With ACURATE Neo™ Aortic Bioprosthesis and ACURATE Neo™ TA Transapical Delivery SystemNo drug interventionsNot AvailableNot Availableterminated
NCT01837160
Angiogenesis and Fibrosis in Aortic StenosisNo drug interventionsNot AvailableNot Availablecompleted
NCT03432494
Transmural Systems Transcaval Closure Device for Transcaval Access Ports During Transcatheter Aortic Valve ReplacementNo drug interventionstreatmentNot Availableterminated
NCT02389894
Neuroprotection in Patients Undergoing Aortic Valve ReplacementNo drug interventionspreventionNot Availablecompleted
NCT02987894
PRospective Observation of Aortic reGuRgitation aftEr TAVI and progreSS Over Time: PROGRESS PVL RegistryNo drug interventionsNot AvailableNot Availablecompleted
NCT05253794
Effect of Colchicine on the Progression of Aortic Valve Stenosis - A Pilot Studyprevention2 / 3recruiting
NCT04417829
Transcatheter Aortic Valve Implantation in Western NORwayNo drug interventionsNot AvailableNot Availablecompleted
NCT01187329
The Effect of the Hyperinsulinemic Normoglycemic Clamp on Myocardial Function and Utilization of GlucoseNo drug interventionstreatmentNot Availablecompleted
NCT04067089
Treatment of Aortic Stenosis in Brazil: Cost-Utility Analysis of TAVI vs SAVRNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT01422044
Risk Prediction in Aortic StenosisNo drug interventionsNot AvailableNot Availablecompleted
NCT05866640
Feasibility Trial of the F2 Filter and Delivery System for Embolic Protection During TAVRNo drug interventionsdevice_feasibility0recruiting
NCT04634240
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve ReplacementNo drug interventionstreatmentNot Availablerecruiting
NCT02486367
Inflammation and Thrombosis in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement (TAVR)basic_science4completed
NCT04388267
Fluid REsponsiveness and Arterial ELASTANCE in Patients With Septic Shock or After Aortic SurgeryNo drug interventionsNot AvailableNot Availableunknown_status
NCT00598767
Three Dimensional Imaging and Wireless Technologies to Enhance Medical Care in SpaceNo drug interventionsNot AvailableNot Availableterminated
NCT02404467
Feasibility And Safety of Early Discharge After Transfemoral Transcatheter Aortic Valve ImplantationNo drug interventionsNot AvailableNot Availablecompleted
NCT04231201
Aortic Stenosis Evaluated Via Modern Ballistocardiography and SeismocardiographyNo drug interventionsNot AvailableNot Availablesuspended
NCT05629104
Prediction of Long-term Outcome in Aortic Stenosis After Valve InterventionNo drug interventionsNot AvailableNot Availablerecruiting
NCT02679404
Sorin Universal REgistry on Aortic Valve ReplacementNo drug interventionsNot AvailableNot Availableterminated
NCT04026204
Reobtain Coronary Ostia Cannulation Beyond Transcatheter Aortic Valve Stent (RE-ACCESS)No drug interventionsNot AvailableNot Availablecompleted
NCT03043404
Performance and Safety of the Lotus™ Valve With a FLEXible Delivery SystemNo drug interventionstreatmentNot Availablecompleted
NCT05625269
The Effect of Education and Follow-up Program in Patients Undergoing TAVINo drug interventionssupportive_careNot Availablecompleted
NCT02207569
Medtronic CoreValve Evolut R U.S. Clinical StudyNo drug interventionstreatmentNot Availablecompleted
NCT01539746
Transcatheter Aortic Valve Implantation Without PredilationNo drug interventionstreatmentNot Availablecompleted
NCT04310046
Optimal Timing of Transcatheter Aortic Valve Implantation and Percutaneous Coronary Intervention - The TAVI PCI TrialNo drug interventionstreatmentNot Availablerecruiting
NCT04489095
Conduction Disease After Transcatheter Aortic Valve ReplacementNo drug interventionsdiagnosticNot Availablecompleted
NCT02675114
PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic StenosisNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT02436655
Aortic Valve Replacement Versus Conservative Treatment in Asymptomatic Severe Aortic StenosisNo drug interventionstreatmentNot Availablecompleted
NCT05235555
EffecTAVI RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT06212050
Feasibility, Safety, and Effectiveness of the ACURATE neo2 Transcatheter Heart Valve for Severe Bicuspid Aortic StenosisNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT02737150
SecOnd-generation seLf-expandable Versus Balloon-expandable Valves and gEneral Versus Local Anesthesia in TAVINo drug interventionstreatmentNot Availableunknown_status
NCT05756608
Fibrosis in Chronic and Delayed Myocardial InfarctionNo drug interventionsNot AvailableNot Availablerecruiting
NCT04585308
transShield Embolic Protection System Feasibility StudyNo drug interventionstreatmentNot Availablecompleted
NCT04307888
Spanish Percutaneous Aortic INtervention REGISTRY (SPAIN REGISTRY)No drug interventionsNot AvailableNot Availableunknown_status