Painful Diabetic Neuropathy (PDN) (DBCOND0085230)

Identifiers

Synonyms
Painful Diabetic Neuropathies / Diabetic Neuropathies, Painful / Painful Diabetic Neuropathy / Diabetic Neuropathy, Painful / Diabetic Neuralgia

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01475786
Safety and Efficacy Study for the Treatment of Painful Diabetic Neuropathytreatment2completed
NCT01928381
Safety, Tolerability and Preliminary Efficacy of AZD5213 in Combination With Pregabalin in Subjects With PDN and Good Pain Reporting Abilitytreatment2completed
NCT02842554
Training "Pain Connoisseurs" for Efficient Analgesic Proof-of-Concept StudiesNo drug interventionsNot Available4completed
NCT04005287
A 24-Week Study of Topical Pirenzepine or Placebo in Type 2 Diabetic Patients (T2DM) With Peripheral Neuropathytreatment2completed
NCT06463015
Posterior Tibial Nerve PRF for Diabetic Neuropathic PainNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03066570
Graded Exposure in Patients With Painful Diabetic NeuropathyNo drug interventionstreatmentNot Availablecompleted
NCT05480228
EPPIC-Net: Novaremed Painful Diabetic Peripheral Neuropathy ISANo drug interventionstreatment2recruiting
NCT06480786
SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial DiseaseNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05985291
BurstDR Stimulation for Painful Diabetic NeuropathyNo drug interventionsNot AvailableNot Availablerecruiting
NCT04678895
Low-Dose Naltrexone for the Treatment of Painful Diabetic Neuropathytreatment2recruiting
NCT00350103
A Trial to Assess the Efficacy and Safety of 400mg/Day Lacosamide in Subjects With Painful Diabetic Neuropathytreatment3completed
NCT03700502
Functional Magnetic Resonance Imaging of Brain Activity in Patients With Painful Diabetic NeuropathyNo drug interventionsNot AvailableNot Availableunknown_status
NCT06383702
A Study to Evaluate Pregabalin in Painful Diabetic Peripheral Neuropathytreatment3not_yet_recruiting
NCT04689984
The Benefits of Astaxanthin as Add on Therapy in the Management of Painful Diabetic Neuropathy Patienttreatment2 / 3unknown_status
NCT00861445
A Trial to Investigate Safety and Efficacy of SPM927 in Painful Diabetic Neuropathytreatment2completed
NCT03700528
The Development of Contextual Cognitive Behavioural Approach to PDNNo drug interventionstreatmentNot Availableunknown_status
NCT00220337
A Trial to Assess the Long-term Safety and Efficacy of Lacosamide in Subjects With Painful Diabetic Neuropathytreatment3completed
NCT05777317
Pain and Neurological Function Improvements With 10 kHz Spinal Cord Stimulation Treatment of Painful Diabetic NeuropathyNo drug interventionstreatmentNot Availablerecruiting
NCT04699734
Peripheral Nerve Block in Patients With Painful Diabetic PolyneuropathyNo drug interventionsdiagnosticNot Availablerecruiting
NCT00337324
Electromagnetic Stimulation (FREMS) in Patients With Painful Diabetic NeuropathyNo drug interventionstreatment2 / 3completed
NCT02355158
A Safety Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Painful Diabetic Neuropathytreatment2completed
NCT05080530
Vitamin D and Painful Diabetic NeuropathytreatmentNot Availableunknown_status
NCT00695565
Efficacy and Safety Study of ARC-4558 for Management of Pain Associated With Painful Diabetic Neuropathytreatment2completed
NCT02068027
Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Pain Associated With Diabetic Neuropathytreatment2completed
NCT04097691
Injection of Subcutaneous Glucose 10% in Small Shots is Effective in the Treatment of Diabetic Neuropathic PainNo drug interventionsNot AvailableNot Availablecompleted
NCT05624762
The Therapeutic Effect of Low-intensity Focused Ultrasound on Painful Diabetic Peripheral NeuropathyNo drug interventionstreatmentNot Availablerecruiting
NCT03331614
An Evaluation of an SCCD on the Symptomatology of Painful DPNNo drug interventionstreatmentNot Availableunknown_status
NCT05754190
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMANo drug interventionsNot AvailableNot Availablerecruiting
NCT04055090
Extension of Phase 3 Gene Therapy for Painful Diabetic NeuropathyNo drug interventionstreatment3completed
NCT02427464
Phase 3 Gene Therapy for Painful Diabetic Neuropathytreatment3completed
NCT05937984
Treatment for Painful Diabetic NeuropathyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06524284
Feasibility of Self-treatment of Painful Diabetic Neuropathy Using Electrical Vasomotor Nerve StimulationNo drug interventionstreatmentNot Availablerecruiting
NCT03202979
Trazodone in Painful Diabetic Neuropathytreatment2completed
NCT02643251
The Efficacy and Safety of Clonidine Hydrochloride Topical Gel, vs Clonidine Hydrochloride Gel Comparator to Treat Painful Diabetic Neuropathytreatment2completed
NCT00546351
Study Evaluating Long-term Safety and Efficacy of Lacosamide in Subjects With Painful Distal Diabetic Neuropathy.treatment3completed
NCT01521598
A Phase 2, Multicenter, Randomized, Double-blind, Placebo Controlled Study for the Pain of Diabetic Peripheral NeuropathyNo drug interventionstreatment2completed
NCT05993871
Diabetic Small Fiber Neuropathy: Clinical, Electrophysiological and Neurosonographic StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT04689971
The Benefits of Vitamin B Combination as Add on Therapy in the Management of Painful Diabetic Neuropathy Patienttreatment2 / 3unknown_status
NCT00703209
Study on the Role of Decompression of Lower Extremity Nerves for the Treatment of Patients With Symptomatic Diabetic Neuropathy With Chronic Nerve CompressionNo drug interventionstreatmentNot Availablecompleted
NCT01125215
Capsaicin Nanoparticle in Patient With Painful Diabetic Neuropathytreatment2 / 3unknown_status
NCT01056315
A Trial in Painful Diabetic Peripheral Neuropathy With GRT3983YNo drug interventionstreatment2terminated
NCT01556152
A Clinical Trial to Study the Effects of GRC 17536 in Patients With Painful Diabetic Neuropathy (Painful Extremities Due to Peripheral Nerve Damage in Diabetic Patients)No drug interventionstreatment2withdrawn
NCT03769675
Quantitative Assessment of Painful Diabetic Peripheral Neuropathy After High Frequency Spinal Cord StimulationNo drug interventionstreatmentNot Availablecompleted
NCT00861042
An Open-label follow-on Trial to Assess the Long-term Safety and Efficacy of Oral SPM 927 in Subjects With Diabetic Neuropathytreatment2completed
NCT03749642
Trazodone/Gabapentin Fixed Dose Combination Products in Painful Diabetic Neuropathytreatment2completed
NCT00837941
A Study of Single Dose Pain Therapy in Patients With Painful Diabetic Neuropathy (0000-115)treatment2withdrawn
NCT04087941
Efficacy and Safety of VM202 in Painful Diabetic Peripheral Neuropathy -The HOPES Trialtreatment2unknown_status
NCT05118217
Microvascular Dysfunction in Diabetic Peripheral NeuropathyNo drug interventionsNot AvailableNot Availableunknown_status
NCT03755934
Efficacy and Safety of MEDI7352 in Subjects With Painful Diabetic NeuropathyNo drug interventionstreatment2completed
NCT06495424
Observational Study to Evaluate the Efficacy of Sustained QUTENZA® Use in Painful Diabetic Peripheral NeuropathyNot AvailableNot Availablenot_yet_recruiting
NCT04689958
The Benefits of Vitamin D 5000 IU as Add on Therapy in the Management of Painful Diabetic Neuropathy Patienttreatment2 / 3unknown_status
NCT01002235
Gene Therapy for Painful Diabetic Neuropathytreatment1 / 2completed
NCT05620225
Axon Therapy and Conventional Medical Management for Painful Diabetic Neuropathy Compared to Sham and Conventional Medical ManagementNo drug interventionstreatmentNot Availablecompleted
NCT04857957
Safety, Tolerability & Pharmacokinetics Study of CNTX-6016 in Healthy Subjects and Subjects With PDNNo drug interventionstreatment1completed
NCT03228420
Comparison of 10 kHz SCS Combined With CMM to CMM Alone in the Treatment of Neuropathic Limb PainNo drug interventionstreatmentNot Availableunknown_status
NCT05476276
EPPIC-Net: Platform Protocol to Assess Treatments for Painful Diabetic Peripheral NeuropathyNo drug interventionstreatment2recruiting
NCT01129960
Eslicarbazepine Acetate as Therapy in Diabetic Neuropathic Paintreatment3terminated
NCT03297294
Safety and Efficacy of EMA401 in Patients With Painful Diabetic Neuropathy (PDN)treatment2terminated
NCT06423391
Multimodal Intervention for Painful Diabetic Neuropathy: NeuOst Feasibility TrialNo drug interventionstreatmentNot Availablerecruiting
NCT04786340
A 12-Week Study of Topical Pirenzepine or Placebo in Type 2 Diabetic Patients (T2DM) With Painful Peripheral Neuropathytreatment2completed
NCT00781001
Efficacy of Inhaled Cannabis in Diabetic Painful Peripheral Neuropathytreatment1 / 2completed
NCT00980746
Efficacy and Safety of Eslicarbazepine Acetate as Therapy for Patients With Painful Diabetic Neuropathytreatment2completed
NCT00501202
Study for Safety and Effectiveness of RWJ-333369 (Carsibamate) for the Treatment of Diabetic Peripheral Neuropathy (DPN).treatment2completed
NCT00858351
Thermal Biofeedback for the Treatment of Diabetic NeuropathyNo drug interventionstreatmentNot Availablecompleted
NCT03315598
Evaluation of an Effectiveness and Safety of the Electroacupuncture in the Management of Intractable Neuropathic PainNo drug interventionstreatmentNot Availablecompleted
NCT05029297
Study With Two Capsaicin Topic Treatments in Diabetic Neuropathy.treatment3completed
NCT01057693
Study Of Pregabalin (Lyrica) In Patients With Painful Diabetic Peripheral Neuropathytreatment3completed
NCT00385671
An Open-Label Comparison of Duloxetine to Other Alternatives for the Management of Diabetic Peripheral Neuropathic Paintreatment4completed
NCT01089556
A Study in Painful Diabetic Neuropathytreatment3completed
NCT02215252
A Clinical Trial To Evaluate PF-05089771 On Its Own And As An Add-On Therapy To Pregabalin (Lyrica) For The Treatment Of Pain Due To Diabetic Peripheral Neuropathy (DPN)treatment2completed
NCT00553475
Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Pregabalin For Pain Associated With Diabetic Peripheral Neuropathytreatment3completed
NCT00539175
Treatment of Painful Diabetic Neuropathy With Photon StimulationNo drug interventionstreatmentNot Availablecompleted
NCT04469270
Study to Assess Safety and Efficacy of Engensis in Painful Diabetic Peripheral Neuropathytreatment3active_not_recruiting
NCT00507936
Safety and Efficacy Study in Subjects With Diabetic Neuropathic Paintreatment2completed
NCT00073034
Study Evaluating EAA-090 in Adult Outpatients With Neuropathic Pain Associated With Diabetic Neuropathytreatment2terminated
NCT01628627
Frequency Modulated Neural Stimulation (FREMS) in Symptomatic Diabetic NeuropathyNo drug interventionstreatment4completed
NCT00553280
A Long-Term Study To Evaluate Safety And Efficacy Of Pregabalin For Pain Associated With Diabetic Peripheral Neuropathytreatment3completed
NCT00141401
Safety and Efficacy of Pregabalin in Patients With Diabetic Peripheral Neuropathy.treatment3completed
NCT01179672
A Study in Participants With Diabetic Peripheral Neuropathic Pain in Chinatreatment3completed
NCT01063868
A Long-term Safety Study With Tapentadol ER and Oxycodone CR in Patients With Moderate to Severe Pain Due to Chronic, Painful Diabetic Peripheral Neuropathy (DPN)treatment3terminated
NCT00058968
A Study for the Treatment of Painful Diabetic Neuropathytreatment3completed
NCT00150423
To Evaluate the Safety and Efficacy of Pregabalin in Patients With Painful Diabetic Peripheral Neuropathy.treatment3completed
NCT00266643
Tolerability of Switching to Duloxetine for the Management of Diabetic Nerve Paintreatment4completed
NCT01214590
Preliminary Assessment of the Efficacy of the VascuActive™ Device on Diabetic Peripheral NeuropathyNo drug interventionstreatmentNot Availableunknown_status
NCT04988321
Theta Burst Brain Stimulation in Diabetic Neuropathy Patients With Neuropathic Pain: Investigating Neural MechanismsNo drug interventionsbasic_scienceNot Availablecompleted
NCT00159679
Pregabalin in the Treatment of Pain Due to Diabetic Peripheral Neuropathytreatment4completed
NCT06152887
Noninvasive Cortical Neurostimulation For Diabetic Neuropathic PainNo drug interventionstreatmentNot Availablerecruiting
NCT00785577
A Study for Treatment of Pain in Patients With Diabetic Neuropathy.treatment2completed
NCT05623111
Perineural Injections of Incobotulinumtoxin-A for Diabetic Neuropathic Pain of the Lower ExtremitiesNo drug interventionstreatment2recruiting
NCT00156078
A Study To Evaluate Pregabalin In Patients With Painful Diabetic Peripheral Neuropathy (DPN)treatment4completed
NCT03047278
Transporters for Organic Cations and Glycemic Control in Patients With Neuropathic Pain.treatment4completed
NCT05670600
The Effect of Foot and Ankle Exercise on Pain and Quality of Life in Patients With Diabetic NeuropathyNo drug interventionssupportive_careNot Availablecompleted
NCT01564459
Study to Evaluate MK-6096 in the Treatment of Painful Diabetic Neuropathy (PDN) in Adults (MK-6096-021)treatment2completed
NCT01332149
Study To Evaluate Efficacy, Safety And Tolerability Of Lyrica In Patients With Painful Diabetic Peripheral Neuropathytreatment3completed
NCT05917249
Efficacy of Noninvasive Radiofrequency in Attenuating Diabetic Neuropathic PainNo drug interventionstreatmentNot Availablecompleted
NCT01050218
Study Evaluating the Long-Term Safety of Desvenlafaxine Succinate Sustained-Release (DVS SR) in Subjects With Pain Associated With Diabetic Peripheral Neuropathytreatment3terminated
NCT00381719
Safety and Efficacy of AGN 203818 in Patients With Painful Diabetic Peripheral Neuropathytreatment2completed
NCT05920434
The Effect of Foot Reflexology and Foot Bath on Paın And Qualıty of Lıfe Applıed to Dıabetıc Neuropathıc PaınNo drug interventionshealth_services_researchNot Availablecompleted
NCT05301816
PDN Post Market, Multicenter, Prospective, Global Clinical StudyNo drug interventionstreatmentNot Availablerecruiting
NCT01793350
Safety and Efficacy Study of BC-DN-01 in Painful Diabetic Peripheral Neuropathytreatment1 / 2withdrawn