Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 (DBCOND0113388)

Identifiers

Synonyms

Not Available

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT06203600	Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial	Lexatumumab Nivolumab Paclitaxel Ramucirumab	treatment	2 / 3	recruiting
NCT06364410	Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors	Azenosertib Trastuzumab deruxtecan	treatment	1	recruiting
NCT04314401	National Cancer Institute "Cancer Moonshot Biobank"	No drug interventions	Not Available	Not Available	recruiting
NCT04535401	Testing the Addition of an Anticancer Drug, BAY 1895344, to the Usual Chemotherapy With FOLFIRI in Advanced or Metastatic Cancers of the Stomach and Intestines	Calcium Camptothecin Elimusertib Fluorouracil Irinotecan Leucovorin Levoleucovorin	treatment	1	active_not_recruiting
NCT04704661	Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Patients With Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial	Ceralasertib Trastuzumab deruxtecan	treatment	1	recruiting
NCT05041153	Pembrolizumab and Lenvatinib for the Treatment of Advanced, Unresectable, or Metastatic Gastroesophageal Adenocarcinoma	Lenvatinib Pembrolizumab	treatment	0	recruiting
NCT04522336	Pembrolizumab and Chemoradiotherapy for the Treatment of Unresectable Gastroesophageal Cancer	Docetaxel Fluorouracil Oxaliplatin Pembrolizumab	treatment	1	active_not_recruiting
NCT03641313	Berzosertib and Irinotecan in Treating Patients With Progressive, Metastatic, or Unresectable TP53 Mutant Gastric or Gastroesophageal Junction Cancer	Berzosertib Irinotecan	treatment	2	active_not_recruiting
NCT04771520	Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors	Avapritinib Benzalkonium	treatment	2	recruiting
NCT04007744	Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors	Pembrolizumab Sonidegib	treatment	1	recruiting
NCT05269381	Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors	Cyclophosphamide Pembrolizumab Sargramostim	treatment	1 / 2	recruiting
NCT05677490	mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma	Fluorouracil Irinotecan Leucovorin Nivolumab Oxaliplatin	treatment	3	recruiting
NCT04460937	Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers	Adavosertib	treatment	1	active_not_recruiting
NCT05733000	CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors	Devimistat Fluorouracil Gemcitabine Hydroxychloroquine Lipoic acid	treatment	2	recruiting
NCT03918499	IRX-2, Cyclophosphamide, and Pembrolizumab in Treating Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Cancer	Cyclophosphamide IRX-2 Pembrolizumab	treatment	1 / 2	completed
NCT03707574	Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study	No drug interventions	Not Available	Not Available	active_not_recruiting
NCT04220827	Paclitaxel for the Treatment of Gastric or Gastroesophageal Cancer	Paclitaxel	treatment	1	active_not_recruiting
NCT04660760	Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer	Lexatumumab Paclitaxel Ramucirumab TAS-102 Tipiracil Trifluridine	treatment	2	recruiting
NCT05651594	Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma	Fluorouracil Leucovorin Oxaliplatin Pembrolizumab Propranolol	treatment	2	recruiting