Pituitary Hormones, Anterior

Name
Pituitary Hormones, Anterior
Accession Number
DBCAT000095
Description

Hormones secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Structurally, they include polypeptide, protein, and glycoprotein molecules.

Drugs
DrugDrug Description
TetracosactideA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
CorticotropinA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
Thyrotropin alfaA recombinant form of thyroid stimulating hormone used in diagnostic testing for thyroid cancer and alongside radioactive agents to destroy thyroid tissue.
MenotropinsA purified combination of human luteinizing hormone and follicle stimulating hormone used to treat female infertility.
SomatotropinA form of recombinant human growth hormone used to treat dwarfism, growth hormone deficiency, and acromegaly as well as to prevent weight loss in HIV patients.
FollitropinA form of recombinant human follicle stimulating hormone used to stimulate follicle development in women with primary ovarian hypogonadism and in men with hypogonadotropic hypogonadism.
PegvisomantA growth hormone receptor antagonist used to treat acromegaly.
UrofollitropinA form of purified human follicle stimulating hormone used to treat infertility in females by inducing follicle development in women without primary ovarian failure.
Corifollitropin alfaA FSH analogue indicated for Controlled Ovarian Stimulation (COS) in combination with a GnRH antagonist for the development of multiple follicles in women participating in an Assisted Reproductive Technology (ART) program.
SomatremA recombinant growth hormone used to treat adult growth hormone deficiency and treat disrupted growth in children due to growth hormone insufficiency or deficiency, turner's syndrome, chronic renal failure, and small stature for gestational age.
BremelanotideBremelanotide is indicated to treat premenopausal women with hypoactive sexual desire disorder that is not due to a medical or psychiatric condition, problems with the relationship, or the effects of...
SetmelanotideSetmelanotide has been investigated for the treatment of obesity.
AlsactideNot Annotated
Luteinizing hormoneNot Annotated
SomapacitanA human growth hormone analog subcutaneous injection indicated for adults with growth hormone deficiency.
Somatropin pegolSomatropin pegol is under investigation in clinical trial NCT00715689 (Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083).
ThyrotropinThyrotropin is under investigation in clinical trial NCT01348191 (Detection of Thyrotrophin Receptor in Human Myometrium).
AlbusomatropinAlbusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth Hormone Deficiency.
Drugs & Drug Targets
DrugTargetType
TetracosactideAdrenocorticotropic hormone receptortarget
CorticotropinAdrenocorticotropic hormone receptortarget
CorticotropinCorticoliberintarget
Corticotropin3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
Corticotropin25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
Corticotropin1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
CorticotropinCytochrome P450 3A4enzyme
Thyrotropin alfaThyrotropin receptortarget
MenotropinsFollicle-stimulating hormone receptortarget
MenotropinsLutropin-choriogonadotropic hormone receptortarget
SomatotropinGrowth hormone receptortarget
SomatotropinProlactin receptortarget
FollitropinFollicle-stimulating hormone receptortarget
PegvisomantGrowth hormone receptortarget
PegvisomantSterol 26-hydroxylase, mitochondrialenzyme
PegvisomantGlutamine synthetaseenzyme
PegvisomantCytochrome P450 2C18enzyme
PegvisomantCytochrome P450 3A4enzyme
PegvisomantCholinesteraseenzyme
PegvisomantCytochrome P450 4A11enzyme
UrofollitropinFollicle-stimulating hormone receptortarget
Corifollitropin alfaFollicle-stimulating hormone receptortarget
SomatremGrowth hormone receptortarget
SomatremInsulin-like growth factor 1 receptortarget
BremelanotideMelanocyte-stimulating hormone receptortarget
BremelanotideMelanocortin receptor 4target
BremelanotideMelanocortin receptor 3target
BremelanotideMelanocortin receptor 5target
BremelanotideAdrenocorticotropic hormone receptortarget
SomapacitanCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
SomapacitanCytochrome P450 2C12, female-specificenzyme
SomapacitanCytochrome P450 1A2enzyme
SomapacitanCytochrome P450 2C19enzyme
SomapacitanSerum albumincarrier
SomapacitanGrowth hormone receptortarget