Penicillin-binding protein 1A

BE0004290ProteinStreptococcus pneumoniae (strain ATCC BAA-255 / R6)pbpA

Cell wall formation. It is acted on by 17 drugs in DrugBank.

Gene name
pbpA
UniProtKB entry
Q8DR59Swiss-Prot
Cellular location
Secreted
Residues / weight
719 residues · 79,701 Da
Also known as
exp2 · Exported protein 2 · PBP-1A · ponA

Resolves to

Protein
UniProtQ8DR59UniProt namePBPA_STRR6
Gene
NCBI Gene934791GenBank153767
Pharmacology
KEGGspr:spr0329
Structure
PDB2C5WPDB2C6WPDB2V2F
Drugs

What you can answer from here — as of September 07, 2019

17DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Penicillin-binding protein 1A, how selective are they, and which programs against it are still in active trials?

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